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標題: | 具拉力控制之高靈敏度連續脈波量測系統 Highly Sensitive Continuous Blood Pulse Wave Monitoring System with Tension Control |
作者: | Yi-Che Tsai 蔡宜哲 |
指導教授: | 楊燿州 |
關鍵字: | 壓力感測器,拉力感測器,動脈張力法,連續脈波偵測,導電高分子,奈米碳管,尼龍濾膜,聚二甲基矽氧烷(PDMS), Pressure sensor,tension sensor,tonometric method,continuous blood pulse wave measurement,conductive polymer,carbon nanotube,nylon membrane filter,polydimethylsiloxane(PDMS), |
出版年 : | 2017 |
學位: | 碩士 |
摘要: | 本研究開發了一具拉力控制之脈壓感測裝置,並將其應用在以動脈張力法之理論基礎之非侵入式連續脈波監測上。此脈波量測裝置由壓力與拉力感測器所組成,將壓力感測器放置於手腕橈動脈上方,並對其施加一固定外力,根據動脈張力法,其所量測到之脈波訊號會與血壓成正關係。而拉力感測器能量化量測時之拉力,使壓力感測器之預壓程度能固定,更能使受試者在最佳與舒適之拉力下量測到穩定且清晰之脈搏訊號,更能標準化量測之預壓,並增加感測效率與完整度。
本研究之壓力與拉力感測器之基礎材料皆為多壁奈米碳管及PDMS聚合物所構成之具微結構的導電高分子與電極所組成,其表面之微結構是以尼龍濾膜為模具,並將其表面之孔隙翻模轉印而成。實驗結果顯示出,本研究之元件具有快速之動態反應,且在脈搏量測之預壓範圍內有線性電阻變化,更重要的是其製程簡單且製造成本低。本研究也成功利用此脈壓感測系統,量測出最適當預壓下之脈搏訊號,並利用後端之訊號處理分析以消除低頻訊號之飄移和高頻雜訊,證實其為可靠之脈壓訊號。而在未來研究中,將可利用此脈搏壓力訊號與連續動態血壓資訊做比較與轉換,並且提供給學術與臨床醫學上做使用。 In this work, a tension controlled pulse wave sensing device for continuous blood pulse wave monitoring based on the tonometric method was presented. The pulse wave sensing device consists of a pressure sensor and a tension sensor installed on a strap. According to the tonometric method, the pressure sensor is placed on the skin above a radial artery by wrapping a strap around the wrist of a patient. The arterial pressure estimated by the pressure sensor. The tension of the strap could be measured by the tension sensor so that the preload of the pressure sensor can be regulated in an appropriate range for measuring a stable and clear pulse wave signals. The sensing element of the proposed pressure and tension sensor consisted of the conductive polymer film made by dispersing multiple carbon nanotubes into polydimethylsiloxane (PDMS) polymer patterned with microdome structures by using the nylon membrane filter as a mold. The proposed device features a rapid dynamic response and the linear resistance changes in the preload range. In addition, the fabricated process of the device was simple and low cost. The drift and high-frequency noise of the pulse wave signals were resolved by Fast Fourier Transform (FFT) and Hilbert Huang Transform (HHT). The measured pulse wave signals can be transformed into continuous dynamic blood pressure signals in the future. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/66924 |
DOI: | 10.6342/NTU201703254 |
全文授權: | 有償授權 |
顯示於系所單位: | 機械工程學系 |
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