穀類擠壓產品對糖尿病大白鼠生理代謝之影響

Abstract

糖尿病是指體內胰島素分泌或作用異常，因而造成血糖過高的現象，並可能引起許多併發症的發生。衛生署最新公佈的民國97年台灣地區的十大死亡原因中，糖尿病為第五位，顯示糖尿病是現今台灣社會所極需關心的健康問題。本實驗選擇一些已知為低升糖指數（glycemic index, GI）或是已經實驗證實具有調節血糖功效的穀物，如：糙米、米麩皮、糙薏仁、薏仁麩皮作為產品原料，以雙軸擠壓機製造成膨發性穀類擠壓產品。而本實驗的主要目的是要評估穀類擠壓產品對STZ（streptozotocin）誘導之糖尿病大白鼠生理代謝的影響。結果顯示，攝取穀類擠壓產品無論有無添加膳食纖維，對STZ誘導之糖尿病大白鼠的醣類及脂質代謝皆無任何影響。但攝取穀類擠壓產品能顯著降低STZ誘導之糖尿病大白鼠的血漿TBARS濃度（p＜0.05）。

Diabetes mellitus（DM）is the disease in which the body dose not produce enough insulin or can’t use its own insulin as well as it should. It causes sugar to accumulate in the blood（hyperglycemia）, and leading to various complication. The Department of Health in Taiwan reported that diabetes was the 5th leading cause of death in Taiwan in 2008. It represents that diabetes is coming to a serious health problem that we have to concern. In present study, I used some cereals that have been concerned with hypoglycemic effect as material to produce expansible extruded cereal products. The contents of the formula are brown rice, rice bran, dehulled adlay and adlay bran. And the objective of this study was to evaluate the effect of extruded cereal product on physiological metabolism in STZ induced diabetic rats. The results of this study demonstrated that the extruded cereal product with or whithout resistance maltodextrin wouldn’t affect the carbohydrate and lipid metabolism of STZ induced diabetic rats. But taking the extruded cereal product could reduce plasma TBARS of STZ induced diabetic rats.