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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/64086
Title: | 狹瓣華八仙枝葉之成分研究 Studies on the Constituents from Leaves and Twigs of Hydrangea angustipetala Hayata |
Authors: | Priyanka Jagannath Patil 帕雅佳 |
Advisor: | 沈雅敬(Ya-Ching Shen) |
Keyword: | 狹瓣華八仙,裂環烯醚萜,苷,山柰酚苷, Hydrangea angustipetala Hayata,secoiridoid glycosides,kaempferol diglycoside, |
Publication Year : | 2012 |
Degree: | 碩士 |
Abstract: | This research consists of isolation and structural elucidation of chemical constituents from Hydrangea angustipetala Hayata. Four known secoiridoid glycosides called hydrangenosides C, D, E, and F (1, 2, 3, 4); 5-O-p-coumaroylquinic acid methyl ester (5) and one kaempferol diglycoside called nicotiflorin (6) were isolated from the ethanol extract of leaves and twigs of Hydrangea angustipetala Hayata by using extensive column chromatography.
Based on the spectroscopic methods such as 1H-NMR and 13C-NMR, including 2D NMR (COSY, HMQC, HMBC and NOESY) experiments, and physical methods such as optical rotation, IR, UV, HRESIMS, the structures of the compounds 1-6 were identified. All the isolated secoiridoid glycosides sent for bioactivity viz. cytotoxicity, anti-inflammatory, antiviral activity. They did not show any significant activity. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/64086 |
Fulltext Rights: | 有償授權 |
Appears in Collections: | 藥學系 |
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File | Size | Format | |
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ntu-101-1.pdf Restricted Access | 2.97 MB | Adobe PDF |
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