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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
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dc.contributor.advisor | 管傑雄(Chieh-Hsiung Kuan) | |
dc.contributor.author | Cheng-Han Lee | en |
dc.contributor.author | 李承翰 | zh_TW |
dc.date.accessioned | 2021-05-20T20:20:56Z | - |
dc.date.available | 2015-08-15 | |
dc.date.available | 2021-05-20T20:20:56Z | - |
dc.date.copyright | 2011-08-15 | |
dc.date.issued | 2011 | |
dc.date.submitted | 2011-08-11 | |
dc.identifier.citation | [1] Yu-Tai Tao, “Structural Comparison of Self-Assembled Monolayers of n-Alkanoic Acids on the Surfaces of Silver, Copper, and Aluminum”, J . Am. Chem. SOC. 1993,115, 4350-4358
[2] M. Kahl and E. Voges, “Analysis of plasmon resonance and surface-enhanced Raman scattering on periodic silver structures”, PHYSICAL REVIEW B 15 VOLUME 61, NUMBER 20MAY 2000 [3] Gang L. Liu and Luke P. Lee, “Nanowell surface enhanced Raman scattering arrays fabricated by soft-lithography for label-free biomolecular detections in integrated microfluidics”, APPLIED PHYSICS LETTERS 87, 074101 (2005) [4] ANDREAS OTTO, “Excitation of Nonradiative Surface Plasma Waves in Silver by the Method of Frustrated Total Reflection”, Zeitschrift ffir Physik 216, 398--410 (1968) [5] H. Fujimaki, Y. , Suzuki and A. Hatta, “Enhanced Raman Scattering from Silver Metal Gratings Coated with p-Nitrobenzoic Acid Films”, JOURNAL OF RAMAN SPECTROSCOPY, VOL. 25, 303-306 (1994) [6] GUAN ZhiQiang , HÅKANSON Ulf , ANTTU Nicklas , WEI Hong , XU HongQi , MONTELIUS Lars & XU HongXing, ” Surface-enhanced Raman scattering on dual-layer metallic grating structures” , Chinese Sci Bull Vol.55 No.24 August (2010) [7] 吳民耀、劉威志, “表面電漿子理論與模擬”, 物理雙月刊(廿八卷二期)2006 年 4 月 [8] Yu-Tai Tao,* Geoffrey D. Hietpas, + and David L. Allara, “HCl Vapor-Induced Structural Rearrangements of n-AlkanoateSelf-Assembled Monolayers on Ambient Silver, Copper, and Aluminum Surfaces”, J. Am. Chem. Soc. 1996, 118, 6724-6735 [9] Mustafa Culha, David Stokes, Leonardo R. Allain, and Tuan Vo-Dinh, ” Surface-Enhanced Raman Scattering Substrate Based on a Self-Assembled Monolayer for Use in Gene Diagnostics”, Anal. Chem. 2003, 75, 6196-6201 [10] NORIO KANEKO, MIHARU KANEKO and HIROAKI TAKAHASHI, “Infrared and Raman spectra and vibrational assignment of some metal tartrates”, Specnochimico Aclo, Vol. 40A. No. I. pp. 3342. (1984) [11] 邱宗凱,錢正浩,連偉男,林奇宏 ”全反射螢光顯微術於生物物理的應用” 物理雙月刊(廿四卷三期)2001年6月 [12] 高書燕,張數霞,楊恕霞,張洪杰 “表面增强拉曼散射活性基底” 《化学通报》2007年 [13] Martin J. Mulvihill, Xing Yi Ling, Joel Henzie, and Peidong Yang “Anisotropic Etching of Silver Nanoparticles for Plasmonic Structures Capable of Single-Particle SERS” J. AM. CHEM. SOC. 2010, 132, 268–274 [14] Cheng Yang, Yu-Tao Xie, Matthew M. F. Yuen, Xiaomin Xiong and C. P. Wong “A facile chemical approach for preparing a SERS active silver substrate” Phys. Chem. Chem. Phys., 2010, 12, 14459–14461 [15] G. MATTEI, L.G.QUAGLIANO and M. PAGANNO, “Surface-Enhanced Raman Scattering (SERS) on Silver Surfaces Activated by a Simple Chemical Treatment.” Europhys. Lett., 11 (4) pp. 373-378 (1990) [16] David L. Allara, Ralph G. Nuzzo, “Spontaneously Organized Molecular Assemblies Quantitative Infrared Spectroscopic Determination of Equilibrium Structures of Solution-Adsorbed n -Alkanoic Acids on an Oxidized Aluminum Surface” Langmuir, Vol. 1, No. 1, 1985 [17] N.E.SCHLO’ITER, Marc D.PORTER’, T.B. BRIGHT and David L.ALLARA, “FORMATION AND STRUCTURE OF A SPONTANEOUSLY ADSORBED MONOLAYER OF ARACHIDIC ON SILVER” CHEMICAL PHYSICS LETTERS Volume 132, number 1, 28 November 1986 [18] Nobuyuki Nishi, Takakazu Nakabayashi and Kentaroh Kosugi, “Raman Spectroscopic Study on Acetic Acid Clusters in Aqueous Solutions: Dominance of Acid-Acid Association Producing Microphases” J. Phys. Chem. A 1999, 103, 10851-10858 [19] NORIO KANEKO, MIHARU KANEKO and HIROAKI TAKAHASHI, “Infrared and Raman spectra and vibrational assignment of some metal tartrates” Specnochimico Aclo, Vol. 40A. No. I. pp. 3342. 1984 [20] 柯富祥,”奈米製造之化學反應及分子元件應用” CHEMISTRY(THE CHINESE CHEM. SOC., TAIPEI)June. 2006 Vol. 64, No.2, pp.273~284 [21] 陳俊顯,蔡東谷 “硫醇自主分子薄膜的形成機制” CHEMISTRY (THE CHINESE CHEM. SOC., TAIPEI) SEP. 2002 Vol. 60, No. 3, pp.391~397 [22] Li-Li Bao, Shannon M. Mahurin, Cheng-Du Liang and Sheng Dai “Study of silver films over silica beads as a surface-enhanced Raman scattering (SERS) substrate for detection of benzoic acid” J. Raman Spectrosc. 2003; 34: 394–398 [23] Alan Campion and Patanjali Kambhampati “Surface-enhanced Raman scattering” Chemical Society Reviews, 1998, volume 27 [24] Jeffrey L. Perry Æ Satish G. Kandlikar “Review of fabrication of nanochannels for single phase liquid flow” Microfluid Nanofluid (2006) 2: 185–193 DOI 10.1007/s10404-005-0068-1 [25] Wen-Pin Shih and Chung-Yuen Hui, “Collapse of microchannels during anodic bonding: Theory and experiments” JOURNAL OF APPLIED PHYSICS VOLUME 95, NUMBER 5 1 MARCH 2004 | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/9402 | - |
dc.description.abstract | 拉曼增強效應是目前理論上與研究上熱門的議題,並廣泛的被應用在各個領域,如生物上的蛋白質研究、醫藥領域的免疫檢測等,這都是因為拉曼增強效應具有快速且準確分析單分子的能力,也因此各種拉曼增強的技術不斷推陳出新,如表面增強拉曼效應、針尖拉曼增強效應等,但至目前為止,能夠將拉曼增強效應「量化」的研究尚無人能夠突破,即拉曼增強的倍數仍然無法定量。本篇論文的目的是透過實驗室新開發的光學模擬計算方法,並搭配合適的實驗環境及量測技巧,期望在拉曼量測下,可以得到訊號增強倍數量化的結果。
本實驗室光學計算方法主要針對週期性光柵結構做模擬,我們發現光柵會因其材質不同、線寬週期不同、深度不同或代測物之介電常數不同,而導致光柵周圍局部電磁場的分佈不一樣,透過模擬,我們找到一個能夠將能量放大的光柵環境,這個環境是設法將水這個物質引入光柵溝槽中,藉由水-介電常數大的特質,將垂直入射光柵的光侷限在水中,也就是說入射能量在水中會產生共振增強的現象,若待測物的分子存在水中,此分子即可得到訊號的放大,這個現象在論文本文中會詳細說明,而依據此模擬,我設計了拉曼即時(real-time)的量測方法來達成此模擬條件。在實驗過程中我們另外發現,在光柵表面有自組裝單層薄膜的產生對於拉曼訊號增強有一定的影響,因此,為驗證此現象,我分別在金光柵及銀光柵表面生成化合物,並加水覆蓋在其上,在此環境下做拉曼即時量測,我們確實得到了訊號增強的結果。在模擬和實驗的數據比較中,我們雖然無法精準預測實驗結果,但模擬和實驗兩者仍有一定的相依性存在。 | zh_TW |
dc.description.abstract | Raman scattering enhancement has been a popular research topic and applied to various fields such as biological protein research and medical immune examination. Raman scattering have the character of rapidly and precisely analyzing molecular structure. Moreover, new techniques of Raman scattering have constantly been invented including surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS) etc. However, there is no research dealing with quantifying the effect of Raman enhancement, that is to say that the enhancement of Raman signal cannot be quantitatively determined. Therefore, under proper experimental environment and gauging skills, the research aims to quantify the enhancement of Raman signal using our lab’s newly developed Optical Computing Method.
The newly developed Optical Computing Method is to simulate periodic grating structure first. We found that grating due to their different materials, different line width period, depth, or different dielectric constant of measuring target, which lead to different local electromagnetic field distribution around grating. By simulating grating structure, we discover a grating environment which can enhance signal. Because of the large dielectric constant of water, making water into the trench of grating will restrict the vertical incident light within the water. The indecent energy will generate resonance in the water and thereby enhance signal. The more detailed phenomena are articulated in the thesis. Based on the simulation, I designed a real-time gauging method to create the simulated condition. During the experiment, I noticed that the self-assemble monolayer (SAM )on the surface of grating influences the effect of Raman enhancement. Therefore, I produced compound on the surface of golden grating and silver grating respectively and cover them by water. Doing the Raman real-time gauging in the aforementioned environment successfully generated the result of signal enhancement. | en |
dc.description.provenance | Made available in DSpace on 2021-05-20T20:20:56Z (GMT). No. of bitstreams: 1 ntu-100-R98945045-1.pdf: 2556880 bytes, checksum: 663a7acc502e4f99b56667cf69bc06e3 (MD5) Previous issue date: 2011 | en |
dc.description.tableofcontents | 論文審定書 I
誌謝 II 中文摘要 III 英文摘要 IV 圖目錄 VIII 表目錄 XI 第一章 導論 1 1-1 前言 1 1-2 論文架構 2 第二章 基本原理介紹 3 2-1 光學模擬計算方法介紹 3 2-2 自組裝單層薄膜介紹 6 2-3量測儀器及量測方法介紹 8 2-3-1 掃描式電子顯微鏡(Scanning Electron Microscope,SEM ) 8 2-3-2 原子力顯微鏡(Atomic Force Microscopic,AFM) 9 2-3-3 聚焦離子束顯微EDS元素分析(Focused Ion Beam – Energy Dispersive Spectrometers) 10 2-3-4 拉曼光譜介紹(Raman Spectrum) 11 第三章 製程與量測方法介紹 13 3-1 晶片製作流程 13 3-1-1 基板清洗(Clean Wafer) 13 3-1-2 光阻塗佈(Spin coating) 14 3-1-3 電子束直寫(E-beam direct write) 15 3-1-4 顯影(Develop) 16 3-1-5 反應性離子蝕刻(Reactive Ion Etching)製程 17 3-1-6 去光阻(PR-remove) 17 3-1-7 真空鍍膜(Evaporation)製程 18 3-2 樣品量測方法 19 3-2-1 純溶液定性量測方法 19 3-2-2 水溶液在晶片上量測方法 20 3-3 製備自組性單層薄膜 22 第四章 模擬結果與實驗結果討論 23 4-1 模擬計算模型分析 23 4-1-1 光柵能量分布的模擬結果 24 4-2 拉曼量測非固態材料實驗結果 26 4-3 拉曼量測實驗結果與模擬比較 30 4-3-1 拉曼即時量測(real-time)結果 30 4-3-2 發現自組性單層薄膜生成 32 4-3-3 自組性單層薄膜對拉曼訊號增強的影響 34 4-3-4 水、光柵、薄膜對拉曼訊號增強之影響 37 4-3-5 自組裝薄膜在銀光柵上之實驗與模擬比較 39 4-3-6 自組裝薄膜在金光柵上之實驗與模擬比較 42 第五章 結論 46 參考文獻 47 | |
dc.language.iso | zh-TW | |
dc.title | 以銀光柵和金光柵模擬與驗證拉曼增強效應 | zh_TW |
dc.title | Simulation and Verification Raman Enhancement with Silver and Gold Grating | en |
dc.type | Thesis | |
dc.date.schoolyear | 99-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 孫允武(Yuen-Wun Suen),孫建文(Kien-Wen Sun),林致庭(Chih-Ting Lin),田維誠(Wei-Cheng Tian) | |
dc.subject.keyword | 拉曼散射增強效應,週期性光柵,光學計算,共振,自組裝單層薄膜, | zh_TW |
dc.subject.keyword | Raman scattering enhancement,grating,optical computing method,resonance,self-assemble monolayer, | en |
dc.relation.page | 50 | |
dc.rights.note | 同意授權(全球公開) | |
dc.date.accepted | 2011-08-11 | |
dc.contributor.author-college | 電機資訊學院 | zh_TW |
dc.contributor.author-dept | 生醫電子與資訊學研究所 | zh_TW |
顯示於系所單位: | 生醫電子與資訊學研究所 |
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