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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 葉安義 | |
| dc.contributor.author | Kai-En Chuang | en |
| dc.contributor.author | 莊鍇恩 | zh_TW |
| dc.date.accessioned | 2021-06-17T01:18:15Z | - |
| dc.date.available | 2020-07-27 | |
| dc.date.copyright | 2017-08-24 | |
| dc.date.issued | 2017 | |
| dc.date.submitted | 2017-08-12 | |
| dc.identifier.citation | 陳時欣。蔗糖酯對奈米/次微米纖維素懸浮液穩定性之研究。國立台灣大學食品科技所碩士論文：台北市，2006。
駱威達。卵磷脂與麥芽糊精對奈米/次微米纖維素懸浮液穩定性及其凍乾粉末覆水性之研究。國立台灣大學食品科技所碩士論文：台北市，2009。 張力文。介質研磨纖維素經不同條件噴霧乾燥的形貌及包覆效用。國立台灣大學食品科技所碩士論文：台北市，2015。 羅少君。介質研磨纖維素經噴霧乾燥後的形貌及包覆。國立台灣大學食品科技所碩士論文：台北市，2015。 高絹智。多孔性纖維素之製備及其特性。國立台灣大學食品科技研究所碩士論文：：台北市，2013。。 A yranci, G.; Tuetuencueler, A., Preparation, storage and stability of juices from different carrot species. Nahrung 1993, 37. Agoda-Tandjawa, G.; Durand, S.; Berot, S.; Blassel, C.; Gaillard, C.; Garnier, C.; Doublier, J. L., Rheological characterization of microfibrillated cellulose suspensions after freezing. Carbohydr. Polym. 2010, 80, 677-686. Anderson, J. W.; Zeigler, J. A.; Deakins, D. A.; Floore, T. L.; Dillon, D. W.; Wood, C. L.; Oeltgen, P. R.; Whitley, R. J., Metabolic effects of high-carbohydrate, high-fiber diets for insulin-dependent diabetic individuals. Am. J. Clin. Nutr. 1991, 54, 936-943. Anderson, J. W.; Baird, P.; Davis, R. H.; Ferreri, S.; Knudtson, M.; Koraym, A.; Waters, V.; Williams, C. L., Health benefits of dietary fiber. Nutr. Rev. 2009, 67, 188-205. Andresen, M., Water-in-oil Emulsions Stabilized by Hydrophobized Microfibrillated Cellulose. J DISPER SCI TECHNOL 2007, 28, 837-844. Aulin, C.; ̈llstedt, M. G.; ̈m, T. L., Oxygen and oil barrier properties of microfibrillated cellulose films and coatings. Cellulose 2010, 17, 559–574. Baruffaldi, R.; Vessoni-Penna, T. C.; Colombo, A. J.; Pitombo, R. N., Effect of storage under ambient conditions on the quality of carrots. Ciencia e tecnologia de alimentos 1983, 3. Boon, C. S.; McClements, D. J.; Weiss, J.; Decker, E. A., Factors influencing the chemical stability of carotenoids in foods. Crit Rev Food Sci Nutr 2010, 50, 515-32. Brown, R. M.; Saxena, I. M.; Kudlicka, K., Cellulose biosynthesis in higher plants. Trends Plant Sci. 1996, 1, 149-156. Chen, B. H.; Peng, H. Y.; Chen, H. E., Changes of carotenoids color, and vitamins content during processing of carrot juice. J. Agric. Food Chem. 1995, 43. Chou, H.-e.; Breene, W. M., Oxidative decoloration of β-carotene in low-moisture model systems. J. Food Sci. 1972, 37, 66-68. Crivelli, G.; Polello, A., Research on quick- freezing of vegetables. III. Suitability of car- rot varieties. Fredoo 1973, 27, 29-30. Deng, X.-X.; Chen, Z.; Huang, Q.; Fu, X.; Tang, C.-H., Spray-drying microencapsulation of β-carotene by soy protein isolate and/or OSA-modified starch. J. Appl. Polym. Sci. 2014, 131. Desobry, S. A.; Netto, F. M.; Labuza, T. P., Preservation of beta-carotene from carrots. Crit Rev Food Sci Nutr 1998, 38, 381-96. Eastwood, M. A.; Kirkpatrick, J. R.; Mitchell, W. D.; Bone, A.; Hamilton, T., Effects of Dietary Supplements of WVheat Bran and Cellulose on Faeces and Bowel Function. Br. Med. J. 1973, 4, 392-394. Fang, X.; Shima, M.; Adachi, S., E#ects of Drying Conditions on the Oxidation of Linoleic Acid Encapsulated with Gum Arabic by Spray-drying. Food Sci. Technol. Res. 2005, 11, 380-384. Gloria, M. B. A.; Grulke, E. A.; Gray, J. l., Effect of type of oxidation on beta-carotene loss and volatile products formation in model systems. Food Chem. 1993, 46, 401-406. Greenberg, E. R.; Baron, J. A.; Tosteson, T. D.; Freeman, D. H.; Beck, G. J.; Bond, J. H.; Colacchio, T. A.; Coller, J. A.; Frankl, H. D.; Haile, R. W.; Mandel, J. S.; Nierenberg, D. W.; Rothstein, R.; Snover, D. C.; Stevens, M. M.; Summers, R. W.; Stolk, R. U. v., A clinical trial of antioxidant vitamins to prevent colorectal adenoma. Polyp Prevention Study Group. N. Engl. J. Med. 1994, 331, 141-147. Habibi, Y.; Lucia, L. A.; Rojas, O. J., Cellulose Nanocrystals: Chemistry, Self-Assembly, and Applications. Chem. Rev 2010, 100, 3479-3500. Haralampu, S. G.; Karel, M., Kinetic Models for Moisture Dependence of Ascorbic Acid and β-Carotene Degradation in Dehydrated Sweet Potato. J. Food Sci. 1983, 48, 1872-1873. Herrick, F. W.; Casebier, R. L.; Hamilton, J. K.; Sandberg, K. R., Microfibrillated Cellulose: Morphology and accessibility. In 9.Cellulose conference, syracuse, NY, USA, 1983; Vol. 37, pp 797-813. Hogan, S. A.; McNamee, B. F.; O’Riordan, E. D.; O’Sullivan, M., <Microencapsulating Properties of Sodium Caseinate.pdf>. J. Agric. Food Chem. 2001, 49, 1934-1938. Iwamoto, S.; Nakagaito, A. N.; Yano, H.; Nogi, M., Optically transparent composites reinforced with plant fiber-based nanofibers. Appl. Phys. A 2005, 81, 1109–1112. Jafari, S. M.; Assadpoor, E.; He, Y.; Bhandari, B., Encapsulation Efficiency of Food Flavours and Oils during Spray Drying. Dry. Technol. 2008, 26, 816-835. Kearsley, M. W.; Rodriguez, N., The stability and use of natural colours in foods: anthocyanin, β-carotene and riboflavin. J. Fd Technol. 1981, 16, 421-431. Koh-Banerjee, P.; Franz, M.; Sampson, L.; Liu, S.; Jr, D. R. J.; Spiegelman, D.; Willett, W.; Rimm, E., Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men. Am. J. Clin. Nutr. 2004, 80, 1237-1245. Kolakovica, R.; Laaksonena, T.; Peltonena, L.; Laukkanenb, A.; Hirvonena, J., Spray-dried nanofibrillar cellulose microparticles for sustained drug release. Int. J. Pharm. 2012, 430, 47-55. Lavoine, N.; Desloges, I.; Dufresne, A.; Bras, J., Microfibrillated cellulose - its barrier properties and applications in cellulosic materials: a review. Carbohydr. Polym. 2012, 90, 735-64. Lee, S.-Y.; Chun, S.-J.; Kang, I.-A.; Park, J.-Y., Preparation of cellulose nanofibrils by high-pressure homogenizer and cellulose-based composite films. Journal of Industrial and Engineering Chemistry 2009, 15, 50-55. Lessin, W. J.; Catigani, G. L.; Schwartz, S. J., Quantification of cis-trans Isomers of Provitamin A Carotenoids in Fresh and Processed Fruits and Vegetables. J. Agr. Food Chem. 1997, 45, 3728–3732. Li, J.-Y.; Taylor, P. R.; Li, B.; Dawsey, S.; Wang, G.-Q.; Ershow, A. G.; Guo, W.; Liu, S.-F.; Yang, C. S.; Shen, Q.; Wang, W.; Mark, S. D.; Zou, X.-N.; Greenwald, P.; Wu, Y.-P.; Blot, W. J., Nutrition intervention trials in Linxian, China: multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia. J. Nati. Cancer Inst. 1993, 85, 1492-1498. Lin, C.-c.; Lin, S.-y.; hwang, L.-s., Microencapsulation of Squid Oil with Hydrophilic Macromolecules for Oxidative and Thermal Stabilization. J. Food Sci. 1995, 60, 36-39. Lin, D.; Li, R.; Lopez-Sanchez, P.; Li, Z., Physical properties of bacterial cellulose aqueous suspensions treated by high pressure homogenizer. Food Hydrocolloids. 2015, 44, 435-442. Lu, J.; Wang, T.; Drzal, L. T., Preparation and properties of microfibrillated cellulose polyvinyl alcohol composite materials. Compos Part A Appl Sci Manuf 2008, 39, 738-746. Menkes, M. S.; Comstock, G. W.; Vuilleumier, J. P.; Helsing, K. J.; Rider, A. A.; Brookmeyer, R., Serum Beta-Carotene, Vitamins a and E, Selenium, and the Risk of Lung Cancer. N. Engl. J. Med. 1986, 315, 1250-1254. Merisko-Liversidge, E.; Liversidge, G. G.; Cooper, E. R., Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur. J. Pharm 2003, 18, 113-120. Mongenot, N.; Charrier, S.; Chalier, P., Effect of Ultrasound Emulsification on Cheese Aroma Encapsulation by Carbohydrates. J. Agr. Food Chem. 2000, 48, 861-867. Muller, R. H.; Peters, K., Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique. Int. J. Pharm. 1998, 160, 229-237. Murray, R., Dietary Fiber. 1977. Olson, J. A., Provitamin A Function of Carotenoids: The Coversion of beta-carotene into Vitamin A. J. Nutr. 1989, 105. Paakko, M.; Ankerfors, M.; Kosonen, H.; Nykanen, A.; Ahola, S.; Osterberg, M.; Ruokolainen, J.; Laine, J.; Larsson, P. T.; Ikkala, O.; Lindstrom, T., Enzymatic Hydrolysis Combined with Mechanical Shearing and High-Pressure Homogenization for Nanoscale Cellulose Fibrils and Strong Gels. Biomacromolecules 2007, 8, 1934-1941. Pasupuleti, V. K.; Anderson, J. W., Nutraceuticals, Glycemic Health and Type 2 Diabetes. 2009. Patravale, V. B.; Date, A. A.; Kulkarni, R. M., Nanosuspensions: a promising drug delivery strategy. J Pharm Pharmacol 2004, 56, 827-40. Peter Kleinebudde, M. J., Firas El Saleh, Influence of Degree of Polymerization on Behavior of Cellulose During Homogenization and Extrusion/Spheronization. AAPS Pharmsci 2000, 2(2), 1-10. Raiva, S. A. R.; Russell, R. M., b-Carotene and Other Carotenoids as Antioxidants. J. Am. Coll. Nutr. 1999, 18, 428-433. Rao, C. N. R.; Cheetham, A. K., Science and technology of nanomaterials: current status and future prospects. J. Mater. Chem 2001, 11, 2887-2894. Re, M. I., MICROENCAPSULATION BY SPRAY DRYING. Dry. Technol. 1998, 16, 1195-1236. Risch, S.; Reineccius, G., Flavor encapsulation. Amer Chem Soc.: Washington DC, 1988. Schultz, S.; Wagner, G.; Urban, K.; Ulrich, J., High-Pressure Homogenization as a Process for Emulsion Formation. Chem. Eng. Technol. 2004, 27, 361-368. Shahidi, F.; Han, X. Q., Encapsulation of food ingredients. Crit. Rev. Food Sci. Nutr. 1993, 33, 501-47. Siems, W.; Salerno, C.; Crifò, C.; Sommerburg, O.; Wiswedel, I., β-Carotene Degradation Products – Formation, Toxicity and Prevention of Toxicity. karger: Basel, 2009; Vol. 61. Siró, I.; Plackett, D., Microfibrillated cellulose and new nanocomposite materials: a review. Cellulose 2010, 17, 459-494. Smith, J.; Steinemann, T., Vitamin A Deficiency and the Eye. Int. ophthalmol clin. 2000, 40, 83-91. Soottitantawat, A.; Yoshii, H.; Furuta, T.; Ohkawara, M.; Linko, P., Microencapsulation by Spray Drying: Influence of Emulsion Size on the Retention of Volatile Compounds. J. Food Sci. 2003, 68, 2256-2262. Stampfer, M. J.; Hu, F. B.; Manson, J. E.; Rimm, E. B.; Willett, W. C., Primary prevention of coronary heart disease in women through diet and lifestyle. The New England Journal of Medicine 2000, 343, 16-22. Syverud, K.; Stenius, P., Strength and barrier properties of MFC films. Cellulose 2009, 16, 75-85. Tajiri, T.; Matsumoto, K.; Hara, K., Storage stability of freeze dried carrots. III The content of carotene as affected by the addition of L-cysteine hydrochloride at various temperature. J. Japanese Soc. Horticultural Sci. 1976, 45. Udawatte, C. S.; Sotheeswaran, S., Immobilization of Selected Microbes at Some Selected Solid Supports for Enhanced Fermentation Process. Ferment Technol. 2015, 4, 1-4. Wagner, L. A.; Warthesen, J. J., Stability of spray dried encapsulation beta-carotenes. J. Food Sci. 1995, 60, 1048-1053. Walker, A. R. P., Crude Fiber, Bowel Motility, and Patten of Diet. S. Afr. Med. J. 1961, 35, 114-115. Wang, S.; Langrish, T., A review of process simulations and the use of additives in spray drying. Food Res. Int. 2009, 42, 13-25. Willett, W. C.; Polk, B. F.; Underwood, B. A.; Stampfer, M. J.; Pressel, S.; Rosner, B.; Taylor, J. O.; Schneider, K.; Hames, a. C. G., Relation of Serum Vitamins a and E and Carotenoids to the Risk of Cancer. N. Engl. J. Med. 1984, 310, 430-434. Wolk, A. M., J. E.; Stampfer, M. J.; Colditz, G. A.; Speizer, F. E.; Hennekens, C. H.; Willett, W. C, Long-term intake of dietary fiber and decreased risk of coronary heart disease among women. JAMA. 1999, 281, 1998-2004. Yu, J.; Anchordoquy, T. J., Effects of Moisture Content on the Storage Stability of Dried Lipoplex Formulations. J Pharm Sci. 2009, 98, 3278-3289. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/67043 | - |
| dc.description.abstract | 包覆技術（encapsulation）目前在食品工業中被廣為應用，利用壁材（wall material）包裹於心材（core）之外，隔絕外界環境如：光照、氧氣、溫度對目標物質之影響，提供保護以提升其化學安定性。前人研究指出濕式介質研磨（Media milling）纖維素有做為包覆壁材之潛力，且文獻亦指出微纖化纖維素具有很好的阻隔性質（barrier property）。因此本實驗透過介質研磨，並加上數次循環之高壓均質作為將纖維素微纖化的方法，以其作為壁材，使用噴霧乾燥（spray drying）包覆β-胡蘿蔔素，探討其對於包覆效果的影響；並藉由儲存安定性試驗，來評估研磨纖維素給予β-胡蘿蔔素的保護效果。
在本實驗中，以經過45分鐘介質研磨的5.5 %（w/w）的纖維素，以高剪切均質（Ploytron）5分鐘或1-5次循環之20000 psi高壓均質（HPH1-5）的方式與 β-胡蘿蔔素混合，接著以進料溫度130 oC進行噴霧乾燥包覆。隨著高壓均質循環次數的增加，研磨纖維素與微纖化程度提高，電子顯微鏡之觀察影像可以看到其形貌從成團的組織，變成細長的微纖維，並且在機械力的作用下有纏繞的現象。且懸浮液黏度隨著均質程度上升而提高。經光學顯微鏡可以看到高壓均質處理後的β-胡蘿蔔素能被均勻的分散成碎片散佈於研磨纖維素中。包覆效果部分以HPH1最佳，裝載率、包覆率與β-胡蘿蔔素回收率分別達54.24 %、37.70 %及69.50 %。儲存安定性實驗的結果顯示，在冷藏及室溫的避光條件下，研磨纖維素的包覆能提升β-胡蘿蔔素的安定性，以HPH1效果最佳，分別達86.84 %及25.75 %。而光照儲存下保護效果則有限。研磨纖維素為具有潛力的β-胡蘿蔔素包覆材料，且綜合包覆效果及儲存安定性的實驗結果，顯示高壓均質一次能得到較佳產物。 | zh_TW |
| dc.description.abstract | Encapsulation is an expanding technique used in food industry. By coating sensitive target ingredient with wall material, many benefits will be provided. And one of the most important advantages is to improve the chemical stability. Light, heat and oxygen can be resisted by wall material, and extend shelf life of core. In this study, milled cellulose, a potential wall material, is used to encapsulate β-carotene by spray-drying. The influence of different homogenization methods of spray-dried infeed solution on encapsulation efficiency is investigated. And the effect of protection to β-carotene will be evaluated through storage stability analysis.
5.5 %(w/w) cellulose was media milled for 45 minutes, and then 3 % (cellulose base) β-carotene was added. The mixtures were processed by rotor-stator mixing (polytron) or 1-5 passes high pressure homogenization (HPH 1-5) to be infeed solution, and spray dried at 130 oC. It showed that the viscosity of infeed solution increased when HPH times increased, and particle size of cellulose became larger. HPH disperse β-carotene more evenly. HPH1 show highest effect of Encapsulation of β-carotene. During 28 days storage at dark conditions, β-carotene retention were increased after encapsulated. And half-life value was prolonged. It indicates that encapsulation can protect β-carotene from degradation when storage, and HPH1 is the best method to preparation the mixture. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-17T01:18:15Z (GMT). No. of bitstreams: 1 ntu-106-R03641024-1.pdf: 9936762 bytes, checksum: d668fbfee6bd75992208c3149f645b75 (MD5) Previous issue date: 2017 | en |
| dc.description.tableofcontents | 壹、前言 1
貳、文獻回顧 2 2.1 纖維素 2 2.1.1 纖維素之基本結構 2 2.1.2 微纖化纖維素 4 2.1.2 纖維素之生理功效 6 2.2 β-胡蘿蔔素 8 2.2.1 β-胡蘿蔔素的基本結構與性質 8 2.2.2 β-胡蘿蔔素的生理功效 8 2.2.3 β-胡蘿蔔素的儲存安定性 9 2.3奈米材料 12 2.3.1 奈米材料的定義 12 2.3.2 奈米材料的製備 13 2.3.3 介質研磨 15 2.4 包覆 16 2.4.1 噴霧乾燥 16 2.4.2 噴霧乾燥過程中影響包覆效果之因子 18 2.5 均質技術 20 2.5.1 高剪切均質 20 2.5.2 高壓均質 20 參、材料與方法 22 3.1 實驗材料 22 3.2 實驗藥品與溶劑 22 3.3 實驗方法 22 3.3.1 纖維素懸浮液製備 22 3.3.2 介質研磨 22 3.3.3 水分含量測定與調整 23 3.3.4 粒徑分析 23 3.3.5 黏度測定 24 3.3.6 β-胡蘿蔔素與研磨纖維素懸浮液之均質 24 3.3.7 噴霧乾燥 25 3.3.8 乾燥粉末之水分含量測定 26 3.3.9 乾燥粉末之回收率 26 3.3.10 表面性質測定 26 3.3.11 掃描式電子顯微鏡觀察 27 3.3.12 纖維素之長寬比 27 3.3.13 穿透式電子顯微鏡觀察 29 3.3.14 包覆率測定 29 3.3.15 β-胡蘿蔔素之定量 30 3.3.16 儲存安定性 31 3.3.17 統計分析 31 3.4 英文代號說明 32 肆、實驗架構 33 伍、結果與討論 34 5.1 掃描式電子顯微鏡觀察 34 5.2穿透式電子顯微鏡觀察 49 5.3纖維素懸浮液之黏度變化 54 5.4粒徑大小與分佈 57 5.5噴乾粉末之密度與孔洞分析 65 5.6 噴霧乾燥粉末的水分含量與回收率 67 5.7 β-胡蘿蔔素之包覆效果 68 5.8 β-胡蘿蔔素之儲存安定性 71 結論 89 參考文獻 91 附錄 100 | |
| dc.language.iso | zh-TW | |
| dc.subject | 高壓均質 | zh_TW |
| dc.subject | 包覆技術 | zh_TW |
| dc.subject | 儲存安定性 | zh_TW |
| dc.subject | β-胡蘿蔔素 | zh_TW |
| dc.subject | 噴霧乾燥 | zh_TW |
| dc.subject | 纖維素 | zh_TW |
| dc.subject | high-pressure homogenization | en |
| dc.subject | beta-carotene | en |
| dc.subject | encapsulation | en |
| dc.subject | cellulose | en |
| dc.subject | storage stability | en |
| dc.subject | spray drying | en |
| dc.title | 微纖化纖維素對β-胡蘿蔔素之包覆作用 | zh_TW |
| dc.title | Encapsulation of β-Carotene by microfabrillated Cellulose | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 105-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 盧訓,張永和,張志欽 | |
| dc.subject.keyword | 纖維素,β-胡蘿蔔素,包覆技術,高壓均質,噴霧乾燥,儲存安定性, | zh_TW |
| dc.subject.keyword | cellulose,beta-carotene,encapsulation,spray drying,high-pressure homogenization,storage stability, | en |
| dc.relation.page | 118 | |
| dc.identifier.doi | 10.6342/NTU201702756 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2017-08-14 | |
| dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
| dc.contributor.author-dept | 食品科技研究所 | zh_TW |
| 顯示於系所單位： | 食品科技研究所 | |
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