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標題: | 樂高模組化微流元件應用於微流晶片之研究 Development and Research on Lego-Type Modular Components for the Application of Microfluidic Chips |
作者: | Dar-Sun Liou 劉達生 |
指導教授: | 陳炳煇(Ping-Hei Chen) |
關鍵字: | 微幫普,微閥門,微流裝置,模組化設計,顆粒分離, micropump,microvalve,microfluidic device,modular design,particles sieving, |
出版年 : | 2009 |
學位: | 博士 |
摘要: | 請參閱英文摘要 A new modular design concept for microfluidic devices is proposed and demonstrated in this work. I design three key modular microfluidic components: membrane pumps, unidirectional membrane valves and guiding-fluid reservoirs, and demonstrate that a microfluidic device with specific functions can be easily assembled with those key modular components. Since all components are combination maneuverable similar to the concept of Lego, this design is named Lego-Type Modular Components or LTMC. My pumps run on man-power so that the assembled microfluidic devices require no other power sources like expensive syringe pumps or air compressors. This feature makes the assembled microfluidic devices completely portable. I also successfully combine my assembled device with other existing mixing microchannels, to serve as the mixing and loading system in PCR experiment to amplify DNA. Besides, I design a simple microchannel to separate particles in fluids by size. With integration of particles sieving chip and LTMC unit to have the control in switching channels, it is successfully found that the size distribution of the head part is different from that of the tail part. This result shows that these modular components can be integrated into other microchannels, implying great potential applications of the modular design. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/43063 |
全文授權: | 有償授權 |
顯示於系所單位: | 機械工程學系 |
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