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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/39050
標題: | 模組化微流元件的優化與效能分析 The Optimization and Performance Analysis of Components of a Modular Microfluidic Chip |
作者: | Meng-Hei Wong 黃銘希 |
指導教授: | 陳炳煇(Ping-Hei Chen) |
關鍵字: | PDMS,模組化元件,微流元件,微流幫浦,微流閥門,微流混合器, PDMS,modular design,micro-fluidic device,micro-pump,micro-valve,micro-mixer, |
出版年 : | 2011 |
學位: | 碩士 |
摘要: | 本研究利用PDMS與CNC加工製作的模具,希望可以製造出以操作簡單、價格低廉、模組化設與計不需要外加電力操控的微流元件。針對微流系統元件(microfluidic devices)中負責流體動力傳輸的微流幫浦(micro-pump)、負責控制流體方向的微流閥門(micro-valve)與負責不同液體混合的微流混合器(micro-mixer),本研究分別研發出微流薄膜幫浦、微流單向閥門和渦漩式半球形微混合器等三大微流元件。
微流薄膜幫浦透過凸輪機構擠壓幫浦的腔室來驅動液體,經實驗證明微流薄膜幫浦的薄膜可以重複按壓最少200次而薄膜不會出現任何破裂;同時微流薄膜幫浦有著穩定的流量與低於7%的液體殘留量(Dead Volume)。微流單向閥門腔室中控制閥門開關的薄膜彈片在關閉的狀態下可以抵受0.4 atm 大氣壓而不會出現任何的滲漏與破裂。最後渦漩式半球形微混合器在特定的雷諾數操作條件下可以達到最高92%的混合效率。 In this study, an attempt is made to use flexible material PDMS with CNC machined mould to fabricate modular mircofluidic devices which are cheap, easy to use and require no electric power. In microfluidc devices, a micro-pump is used for driving the working fluid, a micro-valve is used to control the direction of flow of the working fluid and micro-mixer is used for mixing different kinds of testing fluid. This study designed the above microfluidic devices based on modular concepts : a membrane pump, a unidirectional valve and a vortex-type micromixer. The membrane pump can be pressed by at least 200 times without recognizing any significant damage and have a dead volume below 7% with stable flow rate. The unidirectional valve can withstand a pressure of around 0.4 atm atmospheric pressure without any significant leakage when the valve is closed. And the vortex-type micromixer can have a mixing efficiency as high as 92% under certain Reynolds numbers. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/39050 |
全文授權: | 有償授權 |
顯示於系所單位: | 機械工程學系 |
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