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標題: | 圓錐形離子通道的離子電流整流: 溫度效應與金屬離子偵測 Ionic Current Rectification of Conical Nanochannels: Effect of Temperature and Metal Ions Detection |
作者: | Yung-Che Chen 陳永哲 |
指導教授: | 徐治平 |
關鍵字: | 離子電流整流,圓錐形奈米通道,溫度閘門,重金屬離子偵測, ion current rectification,conical nanochannel,thermal gate,heavy metal detection, |
出版年 : | 2019 |
學位: | 碩士 |
摘要: | 離子電流整流效應(ICR)在奈米孔道內是很重要且有趣的現象。近年來,由於此效應帶來的實際應用讓許許多多科學家紛紛投入這個領域,使得這個領域著實成為奈米科技的一股熱潮。接下來的兩個章節中,我們將會介紹此效應帶來的兩種應用——溫度閘門與重金屬離子的偵測。在第一個章節中,我們透過數值模擬分析來探討電滲透流現象,溶液鹽濃度與溫度在圓錐形奈米孔道中對於離子電流整流效應所造成的影響。我們發現如果忽略電滲透流現象會造成大約90%的偏差。普遍而言,當我們把溶液的溫度提升時,電導會升高而離子電流整流的效應則是變差。當改變溶液鹽濃度時,離子電流整流效應則是會隨濃度呈現一個局部高峰的現象。透過濃度和溫度對於此效應的改變,我們可以設計一個溫度閘門來控制孔道開關。在第二個章節中,我們提出一個新的重金屬離子檢測方法來測量人體內不正常的重金屬離子濃度。利用表面改質,讓奈米孔道內的表面可以吸附重金屬離子並且觀察離子電流整流現象的變化來做偵測。我們透過改變溶液鹽濃度,鉛離子濃度和表面改質情況去檢視不同情況下重金屬離子偵測的表現並且經由數值回歸來找出可偵測的重金屬離子濃度範圍與靈敏度。本實驗結果發現此重金屬離子偵測的方法是可以達到測量人體對於重金屬離子濃度的最低限度。 Ion current rectification (ICR) is interesting and important phenomena in nanochannels and many researchers have been studied this due to its applications in the past few decades. In the following chapter, two kind of application will be introduced, thermal gate and heavy metal ion detection. In Chapter 1, the influence of electroosmotic flow (EOF), bulk concentration and temperature on the degree of ICR are investigated in the conical nanochannel by a thorough numerical simulation. Assuming that the bulk salt concentration ranges from 1 to 1000 mM and temperature from 278 to 313 K, we show that neglecting the EOF effect can lead to ca. 90 % deviation in the degree of ICR. In general, the higher the temperature the greater the conductance and the less significant the ICR effect, and the degree of this effect has a local maximum as the bulk salt concentration varies. A three-dimensional plot correlating the degree of ICR effect on the bulk salt concentration and the temperature is prepared for designing a thermal gate for ionic transport. In Chapter 2, a new way of heavy metal detection is introduced due to the health problem caused by abnormal metal ion concentration in human body. We propose an ion sensing method based on the ion current rectification behavior of a conical nanochannel, using a polyethylene terephthalate nanochannel surface modified by 18-crown-6 to estimate the level of Pb2+ concentration as an example. Numerical simulation is conducted to examine the performance of such as nanochannel under various conditions by varying the bulk LiCl concentration, the level of Pb2+ concentration, and the degree of surface modification. Regression analysis is also conducted to obtain the range of Pb2+ concentration suitable for detection and its lower limit. We show that the performance of the nanochannel proposed is satisfactory. The possibility of detecting Cu2+ by this nanochannel is also discussed. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/72969 |
DOI: | 10.6342/NTU201901560 |
全文授權: | 有償授權 |
顯示於系所單位: | 化學工程學系 |
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