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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 林致廷 | |
| dc.contributor.author | Hua Cheng | en |
| dc.contributor.author | 鄭樺 | zh_TW |
| dc.date.accessioned | 2021-06-15T13:29:04Z | - |
| dc.date.available | 2021-03-08 | |
| dc.date.copyright | 2016-03-08 | |
| dc.date.issued | 2016 | |
| dc.date.submitted | 2016-02-04 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51270 | - |
| dc.description.abstract | 隨著科技持續的進步與醫療概念的演進，重點式照護診斷的儀器成為研究發展的一個重點，在許多發展中的重點式照護診斷技術當中，奈米線場效電晶體是一個以高靈敏度與快速檢出著稱相當有潛力的一支技術，而心肌冠狀動脈綜合症在現代已成為一個嚴重影響人類壽命與生活品質的一個疾病，因此仔細的探索將奈米線場效電晶體應用於急性冠狀動脈診斷的市場是有必要的，同時這個分析也顯示一些當前以奈米線場效電晶體作為重點式照護檢測技術所需克服的議題。
基於市場分析的結果，本論文採用標準商業CMOS製程製作多晶矽奈米線場效電晶體，用於心血管疾病檢測，為了改善由市場分析所總結出的重要議題，本論文以電腦模擬不同摻雜濃度、通道厚度、氧化層厚度的結果，並以實驗測試所製作之奈米線場效電晶體。 | zh_TW |
| dc.description.abstract | As technologies continuously developed, point-of-care testing (POCT) has become an important research direction. Among different developed POCT technologies, nanowire field effect transistor (NW-FET) is one of promising technologies featuring high sensitivity and rapid diagnosis. On the other hand, acute coronary syndrome (ACS) has become a serious cardiovascular disease following developments of human societies. As a consequence, it is intriguing to have a detail market analysis for using NW-FET POCT technology in ACS diagnosis. At the same time, this analysis also shows important issues for the development of NW-FET based POCT technologies.
Based on previous research results, commercial-available CMOS processes can be used to implement poly-silicon NW-FET for cardiovascular biomarker diagnosis. Since the market analysis shows several important issues for the development of NW-FET based PCT technologies, in this work, these issues, such as different doping concentration, oxide thickness, and channel depth, are addressed and verified in simulations. In addition, experiments are also employed to examine the fabricated devices. Based on this work, some of the major obstacles of CMOS-based NW-FET biosensors for POCT applications can be raised and evaluated. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T13:29:04Z (GMT). No. of bitstreams: 1 ntu-105-R02945007-1.pdf: 8307874 bytes, checksum: cd86068f638424705fff6f37e5a78332 (MD5) Previous issue date: 2016 | en |
| dc.description.tableofcontents | 誌謝 i
摘要 ii Abstract iii 目錄 iv 圖目錄 vi 表目錄 viii 第一章 序論 1 第一節 序言 1 第二節 研究動機 2 第三節 論文架構 7 第二章 文獻回顧與原理介紹 8 第一節 生物感測器技術演進 8 第二節 場效電晶體生物感測器原理 9 第三節 奈米線場效電晶體感測器 12 第四節 奈米線場效電晶體生物量測方式與感測影響參數 14 第五節 奈米線場效電晶體生物感測器設計參數 17 第三章 市場與技術評估 19 第一節 產業背景 19 第二節 目標市場 22 第三節 競爭比較 26 第四章 元件設計與實驗方法 30 第一節 奈米線生物感測晶片設計 30 第二節 晶片後製程步驟 33 第三節 生物材料介紹 34 第四節 量測實驗架設與方法 36 第五節 元件模擬 41 第五章 實驗結果與討論 44 第一節 奈米線場效電晶體感測元件 44 第二節 奈米線場效電晶體元件電路量測 48 第三節 訊號正規化處理 50 第四節 空白量測 51 第五節 酸鹼值量測 52 第六節 元件模擬分析 54 第六章 結論與未來展望 64 第一節 結論 64 第二節 未來展望 64 參考文獻 65 | |
| dc.language.iso | zh-TW | |
| dc.title | 奈米線生物感測器感測參數分析與其未來應用於市場之挑戰 | zh_TW |
| dc.title | Factor analysis of nanowire biosensor and its challenges for future application in market | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 104-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 黃念祖,黃榮山,許聿翔 | |
| dc.subject.keyword | 矽奈米線,生物感測器,心臟酵素, | zh_TW |
| dc.subject.keyword | nanowire,biosensor,cardiac enzyme, | en |
| dc.relation.page | 67 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2016-02-05 | |
| dc.contributor.author-college | 電機資訊學院 | zh_TW |
| dc.contributor.author-dept | 生醫電子與資訊學研究所 | zh_TW |
| 顯示於系所單位： | 生醫電子與資訊學研究所 | |
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| ntu-105-1.pdf 目前未授權公開取用 | 8.11 MB | Adobe PDF |
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