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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 王兆麟 | |
| dc.contributor.author | Chi-Lin Yang | en |
| dc.contributor.author | 楊奇林 | zh_TW |
| dc.date.accessioned | 2021-06-15T04:56:10Z | - |
| dc.date.available | 2012-08-06 | |
| dc.date.copyright | 2010-08-06 | |
| dc.date.issued | 2010 | |
| dc.date.submitted | 2010-07-29 | |
| dc.identifier.citation | Ch1
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46162 | - |
| dc.description.abstract | Computed Tomography (CT)-guided intervention has become an integral component of modern patient care. However, due to the lack of real-time visualization feedback, the workflow of the CT-guided intervention involves repeated CT scans, that often lead to prolong operation time and higher radiation dose to the patient.
The objective of this dissertation is to propose a navigation system to streamline the current CT-guided intervention workflow. The goal is to develop a miniature patient-mount navigation system for spinal diseases. The miniature design is the key concept of the system to enable tracking capability without the lost of the accuracy. Another important feature is the auto-registration technique to eliminate the cumbersome registration procedure. To further improve the performance, an intuitive user interface utilizing the virtual bi-plane fluoroscopy technique is proposed. The integrated user interface allows surgeons to follow their already-mastered interventional technique without learning a new protocol. To evaluate the feasibility of the system, three validations are conducted. The first two validations, one with physical phantom and the other with in vitro porcine model, are used to validate machine accuracy and operation error, respectively. The third validation, involving an in vivo clinical human trial, is used to validate the clinical feasibility and efficacy of the system on percutaneous pulsed radiofrequency stimulation of dorsal root ganglion (PRF-DRG). The in vivo human trial shows machine position error 4.6 mm and tilting error 3.6°, which are within the range of conventional fluoro-guided technique. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T04:56:10Z (GMT). No. of bitstreams: 1 ntu-99-D92548002-1.pdf: 3449640 bytes, checksum: 0125d30a7ea85f188f31cd28b3e61a2d (MD5) Previous issue date: 2010 | en |
| dc.description.tableofcontents | Abstract i
List of Figures iv List of Tables vi Chapters: 1 INTRODUCTION 1 1.1 Background and Motivation 1 1.2 Research Objectives and Scopes 3 1.3 Literature Review 4 1.3.1 Image-guided Intervention 4 1.3.2 CT-guided Intervention 5 1.3.3 CT-navigation System for Interventions 9 1.4 Dissertation Organization 11 1.5 Reference 11 2 FAST AND HIGH PRECISION DIGITALLY RECONSTRUCTED RADIOGRAPH GENERATION 14 2.1 Introduction 14 2.2 Background 15 2.2.1. Digitally Reconstructed Radiograph (DRR) Calculation 15 2.2.2. GPU-based DRR Generation 16 2.2.3. Compensation Filter 18 2.3 Materials and Methods 18 2.3.1 Distribution 21 2.3.2 Accumulation 21 2.3.3 Reconstruction 21 2.4 Results 22 2.5 Discussions 25 2.6 Reference 26 3 VIRTUAL FLUOROSCOPY 29 3.1 Introduction 29 3.2 Materials and Methods 30 3.2.1 System description 30 3.2.2 Radiation-Free Training System for Fluoroscopic-guided Intervention 33 3.2.3 Fluoroscopy Interface for CT-navigation System 36 3.3 Results 37 3.4 Discussions 39 3.5 Reference 40 4 DEVELOPMENT OF MINIATURE PATIENT-MOUNTED NAVIGATION SYSTEM 42 4.1 Introduction 42 4.2 Materials and Methods 43 4.2.1 System Overview 43 4.2.2 Miniature Tracking Unit 44 4.2.3 Reference Frame Unit 45 4.2.4 Image Processing Unit 46 4.2.5 Physical Phantom Model 47 4.2.6 In Vitro Porcine Model 48 4.3 Results 50 4.3.1 Registration Accuracy 50 4.3.2 Physical Phantom Model (Mechanical Accuracy) 50 4.3.4 In Vitro Porcine Model (Operative Accuracy) 50 4.4 Discussions 50 4.5 Reference 55 5 CLINICAL TRIAL FOR PERCUTANEOUS PULSED RADIOFREQUENCY STIMULATION OF DORSAL ROOT GANGLION 58 5.1 Introduction 58 5.2 Materials and Methods 60 5.3 Results 66 5.4 Discussions 67 5.5 Reference 71 6 CONCLUSION AND FUTURE WORK 76 6.1 Conclusion 76 6.2 Feature Work 77 | |
| dc.language.iso | en | |
| dc.title | 一個用於電腦斷層導引介入性治療的微型導航系統 | zh_TW |
| dc.title | A Miniature Navigation System for CT-guided Intervention | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 98-2 | |
| dc.description.degree | 博士 | |
| dc.contributor.oralexamcommittee | 曾清秀,方晶晶,顏炳郎,賴達明,溫永銳,楊炳德 | |
| dc.subject.keyword | 手術導航,電腦輔助手術,電腦斷層,雙平面螢光攝影,影像定位, | zh_TW |
| dc.subject.keyword | Surgery navigation,Computer aided surgery,Computed tomography,Bi-plane fluoroscopy,Image registration, | en |
| dc.relation.page | 77 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2010-07-30 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 醫學工程學研究所 | zh_TW |
| 顯示於系所單位： | 醫學工程學研究所 | |
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