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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
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dc.contributor.advisor | 蔡甫昌(Daniel Fu-Chang Tsai) | |
dc.contributor.author | Sin-Bao Huang | en |
dc.contributor.author | 黃馨葆 | zh_TW |
dc.date.accessioned | 2021-05-13T08:36:07Z | - |
dc.date.available | 2016-08-26 | |
dc.date.available | 2021-05-13T08:36:07Z | - |
dc.date.copyright | 2016-08-26 | |
dc.date.issued | 2016 | |
dc.date.submitted | 2016-08-18 | |
dc.identifier.citation | 1. Ko WJ, Chen YS, Tsai PR, Lee PH: Extracorporeal membrane oxygenation support of donor abdominal organs in non-heart-beating donors. Clin Transplant 2000, 14(2):152-156.
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A definition of irreversible coma. Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death. JAMA : the journal of the American Medical Association 1968, 205(6):337-340. 10. Kita Y, Aranami Y, Aranami Y, Nomura Y, Johnson K, Wakabayashi T, Fukunishi I: Japanese organ transplant law: a historical perspective. Prog Transplant 2000, 10(2):106-108. 11. Tojimbara T, Fuchinoue S, Iwadoh K, Koyama I, Sannomiya A, Kato Y, Nanmoku K, Kai K, Nakajima I, Toma H et al: Improved outcomes of renal transplantation from cardiac death donors: a 30-year single center experience. Am J Transplant 2007, 7(3):609-617. 12. Kimura R: Organ transplantation and brain-death in Japan. Cultural, legal and bioethical background. Ann Transplant 1998, 3(3):55-58. 13. The Declaration of Istanbul on organ trafficking and transplant tourism. Transplantation 2008, 86(8):1013-1018. 14. Rhodes R, Schiano T: Transplant tourism in China: a tale of two transplants. 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National Protocol for Donation after Cardiac Death. In.: Australian Organ and Tissue Donation and Transplantation Authority (AOTDTA); July 2010. 22. Shemie SD, Baker AJ, Knoll G, Wall W, Rocker G, Howes D, Davidson J, Pagliarello J, Chambers-Evans J, Cockfield S et al: National recommendations for donation after cardiocirculatory death in Canada: Donation after cardiocirculatory death in Canada. CMAJ 2006, 175(8):S1. 23. Detry O, Le Dinh H, Noterdaeme T, De Roover A, Honore P, Squifflet JP, Meurisse M: Categories of donation after cardiocirculatory death. Transplant Proc 2012, 44(5):1189-1195. 24. Wind J, Faut M, van Smaalen TC, van Heurn EL: Variability in protocols on donation after circulatory death in Europe. Critical care (London, England) 2013, 17(5):R217. 25. Ho TW, Tsai YJ, Ruan SY, Huang CT, Lai F, Yu CJ: In-hospital and one-year mortality and their predictors in patients hospitalized for first-ever chronic obstructive pulmonary disease exacerbations: a nationwide population-based study. PloS one 2014, 9(12):e114866. 26. Hui C, Lin MC, Liu TC, Wu RG: Mortality and readmission among ventilator-dependent patients after successful weaned discharge from a respiratory care ward. Journal of the Formosan Medical Association = Taiwan yi zhi 2010, 109(6):446-455. 27. Yang SM, Huang SC, Kuo SW, Huang PM, Pan SC, Lee JM, Lai HS, Hsu HH: Long-term outcome after bilateral lung transplantation - a retrospective study from a low-volume center experience. BMC Surg 2015, 15:28. 28. Krutsinger D, Reed RM, Blevins A, Puri V, De Oliveira NC, Zych B, Bolukbas S, Van Raemdonck D, Snell GI, Eberlein M: Lung transplantation from donation after cardiocirculatory death: a systematic review and meta-analysis. J Heart Lung Transplant 2015, 34(5):675-684. 29. Daemen JW, Kootstra G, Wijnen RM, Yin M, Heineman E: Nonheart-beating donors: the Maastricht experience. Clin Transpl 1994:303-316. 30. Ledinh H, Bonvoisin C, Weekers L, de Roover A, Honore P, Squifflet JP, Meurisse M, Detry O: Results of kidney transplantation from donors after cardiac death. Transplant Proc 2010, 42(7):2407-2414. 31. Doshi MD, Hunsicker LG: Short- and long-term outcomes with the use of kidneys and livers donated after cardiac death. Am J Transplant 2007, 7(1):122-129. 32. Pine JK, Aldouri A, Young AL, Davies MH, Attia M, Toogood GJ, Pollard SG, Lodge JP, Prasad KR: Liver transplantation following donation after cardiac death: an analysis using matched pairs. Liver Transpl 2009, 15(9):1072-1082. 33. Foley DP, Fernandez LA, Leverson G, Anderson M, Mezrich J, Sollinger HW, D'Alessandro A: Biliary complications after liver transplantation from donation after cardiac death donors: an analysis of risk factors and long-term outcomes from a single center. Ann Surg 2011, 253(4):817-825. 34. Foley DP, Fernandez LA, Leverson G, Chin LT, Krieger N, Cooper JT, Shames BD, Becker YT, Odorico JS, Knechtle SJ et al: Donation after cardiac death: the University of Wisconsin experience with liver transplantation. Ann Surg 2005, 242(5):724-731. 35. Doyle MB, Collins K, Vachharajani N, Lowell JA, Shenoy S, Nalbantoglu I, Byrnes K, Garonzik-Wang J, Wellen J, Lin Y et al: Outcomes Using Grafts from Donors after Cardiac Death. J Am Coll Surg 2015, 221(1):142-152. 36. Blok JJ, Detry O, Putter H, Rogiers X, Porte RJ, van Hoek B, Pirenne J, Metselaar HJ, Lerut JP, Ysebaert DK et al: Long-term results of liver transplantation from donation after circulatory death. Liver Transpl 2016. 37. Oniscu GC, Randle LV, Muiesan P, Butler AJ, Currie IS, Perera MT, Forsythe JL, Watson CJ: In situ normothermic regional perfusion for controlled donation after circulatory death--the United Kingdom experience. Am J Transplant 2014, 14(12):2846-2854. 38. Shapey IM, Muiesan P: Regional perfusion by extracorporeal membrane oxygenation of abdominal organs from donors after circulatory death: a systematic review. Liver Transpl 2013, 19(12):1292-1303. 39. Magliocca JF, Magee JC, Rowe SA, Gravel MT, Chenault RH, 2nd, Merion RM, Punch JD, Bartlett RH, Hemmila MR: Extracorporeal support for organ donation after cardiac death effectively expands the donor pool. J Trauma 2005, 58(6):1095-1101; discussion 1101-1092. 40. Yang HY, Lin CY, Tsai YT, Lee CY, Tsai CS: Experience of heart transplantation from hemodynamically unstable brain-dead donors with extracorporeal support. Clin Transplant 2012, 26(5):792-796. 41. Kootstra G, Kievit J, Nederstigt A: Organ donors: heartbeating and non-heartbeating. World J Surg 2002, 26(2):181-184. 42. Johnson RJ, Bradbury LL, Martin K, Neuberger J: Organ donation and transplantation in the UK-the last decade: a report from the UK national transplant registry. Transplantation 2014, 97 Suppl 1:S1-S27. 43. Hsu CC, Lee CH, Hwang SJ, Huang SW, Yang WC, Chang YK, Tsai DF, Kuo KN: Outcomes of overseas kidney transplantation in chronic haemodialysis patients in Taiwan. Nephrology (Carlton) 2011, 16(3):341-348. 44. Human organ and tissue transplantation: WHA57.18. In: . Edited by Assembly WH; 22 May 2004. 45. Hasegawa T, Maeda Y, Yamakawa K, Tsuchida T, Oshima S: Donor card registration system in Japan: an obstacle to procuring kidneys for transplantation. Health Policy 1995, 33(3):169-177. 46. Siminoff LA, Arnold RM, Hewlett J: The process of organ donation and its effect on consent. Clin Transplant 2001, 15(1):39-47. 47. Rodrigue JR, Cornell DL, Howard RJ: Organ donation decision: comparison of donor and nondonor families. Am J Transplant 2006, 6(1):190-198. 48. Hulme W, Allen J, Manara AR, Murphy PG, Gardiner D, Poppitt E: Factors influencing the family consent rate for organ donation in the UK. Anaesthesia 2016. 49. Williams MA, Lipsett PA, Rushton CH, Grochowski EC, Berkowitz ID, Mann SL, Shatzer JH, Short MP, Genel M: The physician's role in discussing organ donation with families. Critical care medicine 2003, 31(5):1568-1573. 50. Marck CH, Neate SL, Skinner M, Dwyer B, Hickey BB, Radford ST, Weiland TJ, Jelinek GA: Potential donor families' experiences of organ and tissue donation-related communication, processes and outcome. Anaesthesia and intensive care 2016, 44(1):99-106. 51. Tsai DF, Tsai MK, Ko WJ: Organs by firing squad: the medical and moral implausibility of death penalty organ procurement. The American journal of bioethics : AJOB 2011, 11(10):11-13. 52. Caplan A: The use of prisoners as sources of organs--an ethically dubious practice. The American journal of bioethics : AJOB 2011, 11(10):1-5. 53. Bagheri A, Shoji S: The model and moral justification for organ procurement in Japan. J Int Bioethique 2005, 16(1-2):79-90, 194-195. 54. Organ donation [http://www.japantimes.co.jp/news/2014/07/18/reference/organ-donation/] 55. [http://www.jotnw.or.jp/donation/method.html] 56. Wilkinson D: Is it in the best interests of an intellectually disabled infant to die? Journal of medical ethics 2006, 32(8):454-459. 57. Boucek MM, Mashburn C, Dunn SM, Frizell R, Edwards L, Pietra B, Campbell D: Pediatric heart transplantation after declaration of cardiocirculatory death. The New England journal of medicine 2008, 359(7):709-714. 58. Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G et al: An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death. American journal of respiratory and critical care medicine 2013, 188(1):103-109. 59. Ethical controversies in organ donation after circulatory death. Pediatrics 2013, 131(5):1021-1026. 60. . In: Non-Heart-Beating Organ Transplantation: Practice and Protocols. edn. Washington DC: 2000 by the National Academy of Sciences; 2000. 61. Colleges AoMR: A code of practice for the diagnosis and confirmation of death. AMRC, London; 2008. 62. 陳聰富: 民法總則. 台北市: 元照出版公司; 2014. 63. 王皇玉: 刑法上死亡之認定-評最高法院九十五年度台上字第一六九二號判決. 月旦法學雜誌 2010, 185:257-270. 64. Sanchez-Fructuoso AI: Kidney transplantation from non-heart-beating donors. Transplant Proc 2007, 39(7):2065-2067. 65. Domínguez-Gil B, Duranteau J, Mateos A, Núñez JR, Cheisson G, Corral E, De Jongh W, Del Río F, Valero R, Coll E et al: Uncontrolled donation after circulatory death: European practices and recommendations for the development and optimization of an effective programme. Transplant International 2016:n/a-n/a. 66. Karimian N, Matton AP, Westerkamp AC, Burlage LC, Op den Dries S, Leuvenink HG, Lisman T, Uygun K, Markmann JF, Porte RJ: Ex Situ Normothermic Machine Perfusion of Donor Livers. J Vis Exp 2015(99):e52688. 67. Dalle Ave AL, Shaw DM, Bernat JL: Ethical Issues in the Use of Extracorporeal Membrane Oxygenation in Controlled Donation After Circulatory Determination of Death. Am J Transplant 2016, 16(8):2293-2299. 68. Ridley S, Bonner S, Bray K, Falvey S, Mackay J, Manara A: UK guidance for non-heart-beating donation. Br J Anaesth 2005, 95(5):592-595. 69. Miller HC, Alexander JW, Smith EJ, Fidler JP: Salutary effect of phentolamine (Regitine) on renal vasoconstriction in donor kidneys. Experimental and clinical studies. Transplantation 1974, 17(2):201-210. 70. Gould L, Reddy CV, Becker W, Kim SG, Oh KC: Hemodynamic consequences of afterload reduction in patients with valvular abnormalities. J Chronic Dis 1980, 33(7):445-458. 71. Childress JF: Non-heart-beating donors of organs: are the distinctions between direct and indirect effects & between killing and letting die relevant and helpful? Kennedy Inst Ethics J 1993, 3(2):203-216. 72. Carter T, Bodzin AS, Hirose H, West S, Hasz R, Maley WR, Cavarocchi NC: Outcome of organs procured from donors on extracorporeal membrane oxygenation support: an analysis of kidney and liver allograft data. Clin Transplant 2014, 28(7):816-820. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/3709 | - |
dc.description.abstract | 歷史上,器官捐贈移植的發展是從心死後捐贈,其後才有腦死後捐贈,近年來因各國器官供給與需求差距日益擴大,許多國家已經重啟心死後捐贈流程。心死後捐贈在2014年之台北市長選舉中成為焦點,然而,許多對心死後捐贈的批評並非為了理性討論與相互對話,也可能傷害社會大眾對器官移植的信任。本文的目標在於開啟理性對話,以重建社會信任。
本論文之內容在於: 第一、釐清何謂心死後捐贈。從歷史、供需、各國制度的角度看探討台灣施行心死後捐贈的必要性。 第二、從社會對話的角度,討論如何落實民眾之器官捐贈意願徵詢與註記。 第三、從病人自主的角度,建議應該增加器官捐贈意願之選項徵詢,例如是否接受心死後捐贈、願意捐贈的器官種類、是否接受改善器官品質之死亡前介入措施。 第四、探討心死後捐贈曾有過的倫理爭議,包括死亡判定、利益衝突的迴避、死亡前及死亡後介入措施。 第五、探討心死後捐贈是否如何符合台灣現行法律,並比較英、美法律對死亡之定義,以釐清概念。 最後,本文認為心死後捐贈需完善之法規與倫理規範,現在的台灣,已經具備這樣的可能性。然而,在執行上應循序漸進,確保器官捐贈能更公開透明,在尊重病人自主的前提下,用更多的對話重建社會信任。 | zh_TW |
dc.description.abstract | Historically, the development of organ donation began with donation after circulatory death (DCD), followed by donation after brain death (DBD). Many countries reestablished DCD protocol due to the increasing gap between vital organs demand and supply in recent years. DCD became a focus of debates in the 2014 Taipei City mayor election. However, many criticisms of DCD were not intended for rational discussion and dialogue and have hurt the trust for organ donation in the society. The goals of this thesis are to invite a rational dialogue and repair the damaged social trust.
The thesis emphasizes the following: First, to clarify the definition and content of DCD. The necessity to apply DCD in Taiwan was explored, considering history, supply and demand, and global trends. Second, to facilitate mutual dialogue in the society, the methods to implement inquiry and registry of the willingness for organ donation in the general public were discussed. Third, to fulfill the principle of respect for autonomy, additional options in the organ donation registration form were suggested. For example, would the patient accept death determination based on circulatory death criteria, kinds of organ the patient wish to donate, and would the patient accept interventions intended to improve organ quality in end-of-life care. Fourth, to explore the ethical issues arising from DCD, including the determination of death, how to avoid conflict of interests, and antemortem and postmortem interventions. Fifth, to explore if the practice of DCD is legal under current Taiwanese laws. Relevant U.K. and U.S.A. laws were compared to clarify the concepts. Finally, I argue that the implementation of DCD needs comprehensive laws and ethical norms, and Taiwanese society already possesses such potential for the introduction and practice of DCD now. We should make sure, however, that DCD be established on an open and transparent basis and performed in a stepwise and orderly way. Under the premise of respect for autonomy, further mutual dialogue is needed to rebuild social trust. | en |
dc.description.provenance | Made available in DSpace on 2021-05-13T08:36:07Z (GMT). No. of bitstreams: 1 ntu-105-R03457002-1.pdf: 1635652 bytes, checksum: 770276331e6b686d685eb47b9fd70d46 (MD5) Previous issue date: 2016 | en |
dc.description.tableofcontents | 第一章 緒論……………………………………………………………1
第一節 研究背景及動機……………………………………………1 第二節 章節編排……………………………………………………4 第二章 心死後捐贈之意義及推動之理由……………………………6 第一節 名詞釋義……………………………………………………6 第二節 器官捐贈之歷史源流………………………………………9 第三節 心死後器官捐贈之正式分類及各國制度整理……………12 第四節 台灣施行心死後捐贈之必要性……………………………13 第五節 其他增加器官供給,促進公眾利益之方法………………17 第三章 心死後捐贈在倫理與法律上之論證…………………………22 第一節 理論說明……………………………………………………22 第二節 死亡---器官捐贈的倫理與法律基礎………………………24 第三節 控制下心死後捐贈的倫理與法律基礎……………………31 第四節 死亡後介入措施的倫理與法律議題………………………33 第五節 死亡前介入措施的倫理與法律議題………………………43 第四章 對我國心死後捐贈移植制度之建議…………………………49 參考文獻…………………………………………………………………52 | |
dc.language.iso | zh-TW | |
dc.title | 心死後器官捐贈之倫理與法律議題—
開啟對話重建社會信任 | zh_TW |
dc.title | Ethical and Legal Deliberation on Organ Donation after Circulatory Death in Taiwan—
Open the Dialogues and Repair the Social Trust | en |
dc.type | Thesis | |
dc.date.schoolyear | 104-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 陳聰富(Tsung-Fu Chen),徐紹勛(Hsao-Hsun Hsu) | |
dc.subject.keyword | 器官捐贈,心死後捐贈,腦死後捐贈,倫理,法律,人體器官移植條例, | zh_TW |
dc.subject.keyword | organ donation,donation after circulatory death,donation after brain death,ethics,law,Human Organ Transplant Act, | en |
dc.relation.page | 57 | |
dc.identifier.doi | 10.6342/NTU201602624 | |
dc.rights.note | 同意授權(全球公開) | |
dc.date.accepted | 2016-08-18 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 醫學教育暨生醫倫理研究所 | zh_TW |
顯示於系所單位: | 醫學教育暨生醫倫理學科所 |
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