整合電化學檢測功能的雙模態石英微天平振盪器之開拓與研究

Abstract

本研究結合研究團隊所提出之新式電化學交流檢測技術，並且結合石英微天平振盪器，與SC-cut石英晶體切片之技術，成功發展出SC-EQCM，因此取得同時量測電化學(電流、血糖濃度)、SC-cut B模態量取樣本溫度變化、SC-cut C模態量取樣本黏滯性與質量特性等三種主要參數的量測能力。於電化學方面，本論文成功証明了於QCM上可以使用弦波交流供電或直流供電來做電化學反應，而此反應又不會影響到QCM的量測。而在QCM量測上更發展出一種新系統，利用SC- cut 石英晶體之特性，可不用外加溫度感測器來量取自我溫度，在實驗中更建立了SC-cut B模態溫度曲線資料庫，並且利用簡單的酸鹼中和實驗驗証了系統的多變數量測能力。 最後在整合SC-EQCM量測系統中，設計出兩種不同的白金電極探針(流道式與滴定式)，並且利用LabVIEW的程式成功設計出可以同量測三種參數的人機介面，在電化學方面確認出電流與不同濃度葡萄糖呈現線性關係，而B 模態在不同濃度中可以檢測出氧化還原現象，而C模態則可以量測到黏滯性的關係。

A SC-EQCM has been developed in this thesis by integrating a dual-mode SC-quartz and a Electrochemistry detection capabilities. The SC-EQCM depicts that SC-quartz can use B-mode signals as a self- temperature sensor to achieve a - 550HzΔf/°C linearity, and can use C-mode signals as a mass (viscosity..) sensor. In addition, the Electrochemistry sub-system, which was demonstrated to integrate well with the QCM as its input AC or AC ride on DC signals will not influence QCM signals, provides the newly developed system with many new found biochemistry detection capabilities. In SC-EQCM experiment, what was equipped with two platinum electrode, used LabVIEW to measure the B-mode and the C-mode frequency and electric current simultaneously. Experimental results indicated that the current is linearly proportional the concentration of glucose, the B-mode frequency can measure the redox phenomenon, and the C-mode frequency can detect the viscosity variations.