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標題: | 用於人耳成像的小型手持式光學同調斷層掃描儀裝置開發 Development of a Small Handheld Optical Coherence Tomography Device for Human Ear Imaging |
作者: | 康博 Bo Kang |
指導教授: | 李翔傑 Hsiang-Chieh Lee |
關鍵字: | 光學同調斷層掃描術,小型化OCT系統,微機電掃描技術,人體耳蝸植入術,中耳炎, optical coherence tomography,miniature OCT system,otitis media,microelectromechanical system scanning technologies,human cochlear implantation, |
出版年 : | 2023 |
學位: | 碩士 |
摘要: | 在此論文研究中,我們提出了一種用於人耳成像的手持式SS-OCT系統。系統光源為中心波長1060 nm、掃描速率100 kHz和頻寬100 nm的掃頻雷射光源,通過微機電掃描技術和梯度折射率棒(GRIN)的結合可以為成像平台提供2.5 mm × 2.5 mm的掃描範圍,此系統的軸向解析度和橫向解析度分別是13.3 μm和20 μm。我們開發此系統預期用於在人工耳蝸植入術中判斷耳蝸內各種內膜及腔室的位置,進行實時監控以保證人工電極陣列的正確放置;以及通過耳道對鼓膜和中耳進行成像來輔助診斷,以提高中耳疾病的診斷準確率。我們針對膠帶及人類手指進行OCT成像,分別展示了各樣品的結構特徵,這些結果成功地顯示了所開發之成像平台於人耳成像的可行性。基於此論文結果,在未來的展望上,我們將進一步從優化所開發之成像平台,增加引導攝像頭縮小其體積,以及嘗試與極化OCT系統整合,以助於其在臨床應用的早日實現。 In this thesis work, we report a handheld swept-source OCT (SS-OCT) system for imaging the human ear. Using a laser light source with a central wavelength of 1060 nm, an optical bandwidth of 100 nm, and an A-scan rate of 100 kHz. The axial and lateral resolutions of the OCT system were measured to be 13.3 μm and 20 μm, respectively. The small footprint imaging platform can support an imaging field-of-view (FOV) of 2.5 mm × 2.5 mm using a MEMS scanner and gradient index (GRIN) optical components. We developed this system for judging the position of various inner membranes and chambers in the cochlea during cochlear implantation, and performing real-time monitoring to ensure the correct placement of artificial electrodes. And we use the ear canal to image the tympanic membrane and middle ear to assist in diagnosis, so as to improve the diagnostic accuracy of middle ear diseases. We performed OCT imaging on tape and human fingers, which respectively showed the structural characteristics of each sample. These results successfully demonstrated the feasibility of the developed imaging platform for imaging the human ear. Based on the results of this paper, in the future we will further optimize the developed imaging platform, reduce its size by adding a guiding camera, and try to integrate it with a polarized OCT system to achieve clinical application as soon as possible. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/87732 |
DOI: | 10.6342/NTU202301014 |
全文授權: | 同意授權(限校園內公開) |
顯示於系所單位: | 光電工程學研究所 |
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