智能專利：快速草擬化學專利範圍的智慧系統

Abstract

要自動生成化學專利的草稿，首先必須草擬用來定義專利範圍的馬庫斯結構與取代基列表，目前這項工作重度仰賴有經驗的專利律師或事務所，能用的輔助工具也很少，「智慧專利」的用途便是加速這項程序。使用者只需上傳結構相似的化合物，智慧專利便會自動分析出共通的主結構並生成專利範圍的文字定義。此程式也能在所有結構變化處新增常見於過去美國銷售排行前30名的藥物專利的取代基，藉此延伸專利保護範圍。程式輸入的檔案格式為SDF檔，其中不變的核心結構和可變的取代基將分別輸出成馬庫斯結構中最初的骨架以及取代基，運算結果能下載成word(.docx)檔。「智慧專利」是能快速生成建議專利範圍的網路工具，可從網址(https://intellipatent.cmdm.tw/)免費造訪。

The first step of automating composition patent drafting is to draft the claims around a Markush structure with substituents. Currently, this process depends heavily on experienced attorneys or patent agents, and few tools are available. IntelliPatent was created to accelerate this process. Users can simply upload a series of analogs of interest, and IntelliPatent will automatically extract the general structural scaffold and generate the patent claim text. The program can also extend the patent claim by adding commonly seen R groups from historical lists of the top 30 selling drugs in the US for all R substituents. The program takes MDL SD file formats as inputs, and the invariable core structure and variable substructures will be identified as the initial scaffold and R groups in the output Markush structure. The results can be downloaded in MS Word format (.docx). The suggested claims can be quickly generated with IntelliPatent. This web-based tool is freely accessible at https ://intellipatent.cmdm.tw/.