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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/8297
標題: | 基於深度學習之老鼠腦部磁振影像中風區域分割研究 Stroke Lesion Segmentation in Rat Brain MR Images Based on Deep Learning |
作者: | Shih-Hsin Ho 何世馨 |
指導教授: | 張恆華(Herng-Hua Chang) |
關鍵字: | 深度學習,卷積神經網路,磁共振成像,缺血型腦中風,影像分割, deep learning,convolutional neural network (CNN),magnetic resonance imaging (MRI),ischemic stroke,image segmentation, |
出版年 : | 2020 |
學位: | 碩士 |
摘要: | 腦中風長期是造成人類死亡的主要原因之一,依型態可以分為腦缺血及腦出血兩大類,而磁共振成像 ( Magnetic Resonance Imaging, MRI ) 之影像可以作為初步之腦中風判讀依據。在相關實驗中,齧齒動物老鼠時常選擇為實驗動物,以其中風腦部影像作為研究基礎。而在研究上,腦中風影像之中風區域選取及判讀需要腦神經專家處置,這是一件繁鎖且耗時的任務,並有標準一致性上的問題。本研究以深度學習為基礎,針對磁共振成像中 T2 加權成像及擴散加權成像 ( Diffusion Weighted Imaging, DWI ) 之影像,開發腦中風影像自動分割中風區域之模型。透過全卷積神經網路為基礎架構,當中加入本研究所提出之混合殘差塊,並使用 3528 張 T2 和 3024 張 DWI 增強後之影像分別進行訓練。檢視實驗結果,以本架構針對兩種影像各別訓練之模型,能在訓練資料以外之測試資料有優異的分割結果。在分割 T2 影像中風區域中達到 86.84% 的準確度,並在 DWI 影像中達到了 87.36% 的準確度。 Stroke has been one of the main causes of human deaths for a long time. Stroke can be divided into two types: ischemic and hemorrhagic. Magnetic Resonance Imaging (MRI) can be used as a preliminary interpretation basis for stroke. In related experiments, mice are often selected as experimental animals, and their brain images are used for research. Usually, the determination and segmentation of stroke areas in rat brain stroke images requires manual processing by neurological experts. This process is complicated and time-consuming, and may have different standards. This thesis develops a model based on deep learning for automatically segmenting stroke regions in T2 Weighted and Diffusion Weighted image (DWI) images. Into the fully convolutional network as the basic structure, the mix block proposed by this thesis is incorporated. The network is trained using 3528 T2 and 3024 DWI augmented images. The experimental results show that the two models trained separately for the two types of rat images with this architecture have excellent stroke segmentation results in the test data. The T2 image segmentation result has 86.84% accuracy, and the DWI image achieved 87.36% accuracy. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/8297 |
DOI: | 10.6342/NTU202002636 |
全文授權: | 同意授權(全球公開) |
顯示於系所單位: | 工程科學及海洋工程學系 |
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U0001-0708202014502200.pdf | 6.92 MB | Adobe PDF | 檢視/開啟 |
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