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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 方煒(Wei Fang) | |
| dc.contributor.author | Yi-Chia Shan | en |
| dc.contributor.author | 單益嘉 | zh_TW |
| dc.date.accessioned | 2022-11-25T03:06:22Z | - |
| dc.date.available | 2024-10-21 | |
| dc.date.copyright | 2021-11-02 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-10-22 | |
| dc.identifier.citation | 1. Aasthik Upadhyay, Abhimanyu S. Dhapola. Embedded Systems and its Application in Medical Field in Emerging Trends in Computer Science and Information Systems(NCETCSIS-2015), March 2015. 2. W. O. Tatum, A. M. Husain, S. R. Benbadis, and P. W. Kaplan. 2007. Handbook of EEG INTERPRETATION. 3. C. W. Mundt, K. N. Montgomery, U. E. Udoh et al. 2005. A Multiparameter Wearable Physiologic Monitoring System for Space and Terrestrial Applications. IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE. VOL. 9, NO. 3. 4. M. Teplan. 2002. FUNDAMENTALS OF EEG MEASUREMENT. MEASUREMENT SCIENCE REVIEW. Volume 2, Section 2. 5. C. Baker, K. Armijo, S. Belka, M. Benhabib, V. Bhargava, N. Burkhart, A. Der Minassians, G. Dervisoglu, L. Gutnik, M. Haick, C. Ho, M. Koplow, J. Mangold, S. Robinson, M. Rosa, M. Schwartz, C. Sims, H. Stoffregen, A. Waterbury, E. Leland, T. Pering, and P. Wright. 2007. 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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/81909 | - |
| dc.description.abstract | "本篇論文主要是利用嵌入式系統，進行低功率光生物刺激與生理訊號量測的相關性研究與應用，並開發醫療器材及導盲輔具。開發系統主要包括微處理器、光驅動電路、生理訊號量測模組。其中以低功率LED或laser做為光生物刺激源，探討低能量光刺激對人體的生理影響。生理訊號量測主要有腦電信號 (EEG)、心電信號 (ECG)及光體積變化信號 (PPG)。根據擷取的生理信號分析腦波、心律變異及自律神經狀態。設計的系統可將數位化的資料透過RS232通訊傳至外部電腦，做進一步儲存、分析與顯示。 實驗結果發現 LED (850 nm)刺激會引起大腦枕葉、頂葉和顳葉區域的alpha (8-13 Hz)活動發生顯著變化。Theta (4-7 Hz) 功率在大腦的後部區域也有顯著增加。當光刺激停止後，影響效果至少持續15分鐘。比較低功率LED (850 nm, 30 mW/pcs, pulse frequency 10 Hz)與低功率laser (830 nm, 7 mW/pcs, pulse frequency 10 Hz)刺激的研究，LED與laser對alpha (8-13 Hz)活動具有相似的影響。 在醫療器材開發方面，首先完成ECG量測和低功率LED驅動的裝置，以LED (850 nm) 光照射受測者內關穴，並使用ECG信號偵測心律變異 (HRV)。比較LED照射前後HRV數值，顯示自律神經 (ANS)狀態有影響。接著開發PPG信號量測和低功率LED刺激的裝置，比較PPG信號及市售的ECG的量測結果，發現兩者的HRV指標的一致性程度高。顯示健康的受測者安靜坐在椅子上，PPG信號可取代ECG信號來量測心律。另外實驗結果顯示以LED (850 nm) 光照射左手掌心，會影響自律神經系統 (ANS)，交感神經系統 (SNS)的狀態有提升，後續仍需做更多測試驗證。 此外，結合雷射光學與攝影機，開發一個具有偵測距離和障礙物寬度的導盲輔具，並將結果以語音方式通知使用者。實驗結果顯示，在40和120 cm範圍內，偵測距離的標準差小於5%，偵測障礙物寬度的標準差小於4.5%。設計系統具有架構簡單、非手持及低成本的優點。" | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-25T03:06:22Z (GMT). No. of bitstreams: 1 U0001-1410202121193500.pdf: 3547256 bytes, checksum: d37d714982120a0b3278aea0d9e50132 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | "誌謝 i 中文摘要 ii Abstract iv List of Figures x List of Tables xvii 1. Introduction 1 2. Literature review 5 2.1. Process and control system 5 2.1.1. Embedded system 5 2.2. Physiological signal monitoring (ECG, EEG, PPG) 9 2.2.1. Electrocardiography (ECG) 9 2.2.2. Photoplethysmography (PPG) 11 2.2.3. Electrocepholography (EEG) 13 2.3. Low power photobiostimulation (Laser and LED) 16 2.3.1. Photo effect 16 2.3.2. Low power photo therapy 20 2.3.3. ANS and brainwave activity by low power photo therapy 24 2.4. Guidnce system for blind 26 2.4.1. Laser range finders 26 2.4.2. Blind guidances 27 3. Materials and Methods 29 3.1. System design 29 3.1.1. Signal-processing module 29 3.1.2. ECG module 31 3.1.3. LED Array Arrangement and dose calculation 32 3.2. Calculation method 33 3.2.1. ECG heart rate calculation 33 3.2.2. PPG heart rate calculation 35 3.2.3. HRVcalculation 38 3.2.4. HRV metrics agreement 41 4. Researches and Discussion 43 4.1. Effect of Near-Infrared Pulsed Light on the Human Brain Using Electroencephalography. 43 4.1.1. Experimental Section 43 4.1.2. Results 48 4.1.3. Discussion 58 4.1.4. Brief conclusion 65 4.2. The Embedded System Integrated ECG Monitoring and Low Energy Led Light Stimulation 67 4.2.1. Experimental section 67 4.2.2. Result 69 4.2.3. Discussion 71 4.2.4. Conclusions 72 4.3. A system based on photoplethysmography and photo-biostimulation for HRV monitoring and ANS adjustment 73 4.3.1. Experimental section 73 4.3.2. Result 78 4.3.3. Discussion 86 4.3.4. Brief conclusion 91 4.4. Blind guidance system based on laser triangulation 92 4.4.1. Measurement Principle 92 4.4.2. Results 103 4.4.3. Brief conclusion 108 5. Conclusion 109 6. Future work 111 Reference 113 Appendices 127" | |
| dc.language.iso | en | |
| dc.subject | 心電信號 | zh_TW |
| dc.subject | 嵌入式系統 | zh_TW |
| dc.subject | 光體積描述信號 | zh_TW |
| dc.subject | 心律變異 | zh_TW |
| dc.subject | 自律神經系統 | zh_TW |
| dc.subject | 腦電信號 | zh_TW |
| dc.subject | 低功率光生物刺激 | zh_TW |
| dc.subject | PPG | en |
| dc.subject | embedded system | en |
| dc.subject | low-power photobiostimulation | en |
| dc.subject | HRV | en |
| dc.subject | ANS | en |
| dc.subject | EEG | en |
| dc.subject | ECG | en |
| dc.title | 嵌入式系統於光生物刺激與醫療器材及輔具應用 | zh_TW |
| dc.title | "The applications of embedded system in photobiostimulation, medical and assistive devices" | en |
| dc.date.schoolyear | 109-2 | |
| dc.description.degree | 博士 | |
| dc.contributor.author-orcid | 0000-0002-0852-690X | |
| dc.contributor.advisor-orcid | 方煒(0000-0002-9724-898X) | |
| dc.contributor.oralexamcommittee | 吳季華(Hsin-Tsai Liu),江昭皚(Chih-Yang Tseng),鄭宗記,林啟萬 | |
| dc.subject.keyword | 嵌入式系統,低功率光生物刺激,心律變異,自律神經系統,腦電信號,心電信號,光體積描述信號, | zh_TW |
| dc.subject.keyword | embedded system,low-power photobiostimulation,HRV,ANS,EEG,ECG,PPG, | en |
| dc.relation.page | 133 | |
| dc.identifier.doi | 10.6342/NTU202103734 | |
| dc.rights.note | 同意授權(全球公開) | |
| dc.date.accepted | 2021-10-25 | |
| dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
| dc.contributor.author-dept | 生物機電工程學系 | zh_TW |
| dc.date.embargo-lift | 2024-10-21 | - |
| 顯示於系所單位： | 生物機電工程學系 | |
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| U0001-1410202121193500.pdf | 3.46 MB | Adobe PDF | 檢視/開啟 |
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