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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 周呈霙(Cheng-Ying Chou) | |
| dc.contributor.author | Chien-Han Tsou | en |
| dc.contributor.author | 鄒建瀚 | zh_TW |
| dc.date.accessioned | 2022-11-24T09:26:41Z | - |
| dc.date.available | 2022-11-24T09:26:41Z | - |
| dc.date.copyright | 2021-11-03 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-10-27 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/81748 | - |
| dc.description.abstract | "冠狀動脈疾病是最常見的心血管疾病，並且為全球最致命的疾病。而心導管檢查是最有效的冠狀動脈疾病檢查手段，冠狀動脈造影 (coronary angiography image, CAG)影像以及血流儲備分數(fractional flow reserve, FFR)會在檢查中取得。本研究應用影像三維重建演算法，利用多個冠狀動脈造影影像重建出三維冠狀動脈結構。並與電腦斷層冠狀動脈血管攝影(coronary computed tomography angiography, CCTA)中的血管結構做對位，結合兩影像診斷工具之優勢，電腦斷層冠狀動脈血管攝影可以提供斑塊的資訊，而冠狀動脈造影擁有更準確的管徑資訊，兩影像融合的結果可以提供診斷上更多的參考依據。計算流體力學(Computational fluid dynamics, CFD)方法將用於模擬動脈內的壓力分佈，作為判斷心肌缺血可能性的依據。兩種不同的血液質量流率估算方法將於本研究中應用，模擬出的結果可作為判斷冠狀動脈疾病之依據。其中方法一從冠狀動脈造影影像中提取出血液流速資訊，因不需要電腦斷層冠狀動脈血管攝影資訊，使其應用上的限制更少，而方法二從電腦斷層冠狀動脈血管攝影影像中提取出心肌大小資訊，擁有更好的分類準確率。透過上的述重建演算法，所得到的結果可應用於多個面相，藉以輔助冠狀動脈疾病檢查。" | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-24T09:26:41Z (GMT). No. of bitstreams: 1 U0001-2510202110532000.pdf: 11972045 bytes, checksum: 7c737049e227eb616be95e642f4dfc6f (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | Verification Letter from the Oral Examination Committee i Acknowledgements ii 摘要 iii Abstract iv Contents vi List of Figures viii List of Tables x Chapter 1 Introduction 1 1.1 Coronary artery disease 1 1.2 Diagnosis and treatment 1 1.3 Objective 2 Chapter 2 Literature Review 4 2.1 Image acquisition geometry 5 2.2 Deal with cardiac motion 6 2.3 Model-based reconstruction 7 2.3.1 Forward-projection-based methods 8 2.3.2 Back-projection-based methods 10 2.4 Lumen reconstruction 11 Chapter 3 Materials and Methods 12 3.1 Materials 12 3.1.1 Study population 12 3.1.2 Coronary angiography (CAG) 13 3.1.3 Coronary computed tomography angiography (CCTA) 14 3.1.4 ANSYS Fluent system 16 3.2 Methods 16 3.2.1 Coronary angiography preprocessing 18 3.2.2 Coronary angiography lumen labeling 25 3.2.3 Coronary artery Lumen reconstruction 27 3.2.4 Registration of 3D CAG and 3D CCTA coronary artery 37 3.2.5 Fractional flow reserve simulation 39 Chapter 4 Results and Discussion 43 4.1 Comparison with CAG 44 4.2 Comparison with CCTA 52 4.3 Comparison between FFR values 57 4.4 Discussion 59 Chapter 5 Conclusions 61 References 63 | |
| dc.language.iso | en | |
| dc.subject | 冠狀動脈導管檢查 | zh_TW |
| dc.subject | 血流儲備分數 | zh_TW |
| dc.subject | 三維重建 | zh_TW |
| dc.subject | Fractional flow reserve | en |
| dc.subject | Three dimensional reconstruction | en |
| dc.subject | Coronary Angiography | en |
| dc.title | 心導管影像之三維重建與計算流體力學之應用 | zh_TW |
| dc.title | Three Dimensional Lumen Reconstruction and Computational Fluid Dynamics Application of Coronary Angiography | en |
| dc.date.schoolyear | 109-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 王偉仲(Hsin-Tsai Liu),傅楸善(Chih-Yang Tseng),黃裕城 | |
| dc.subject.keyword | 冠狀動脈導管檢查,三維重建,血流儲備分數, | zh_TW |
| dc.subject.keyword | Coronary Angiography,Three dimensional reconstruction,Fractional flow reserve, | en |
| dc.relation.page | 68 | |
| dc.identifier.doi | 10.6342/NTU202104120 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2021-10-28 | |
| dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
| dc.contributor.author-dept | 生物機電工程學系 | zh_TW |
| 顯示於系所單位： | 生物機電工程學系 | |
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