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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 曾明宗(Ming-Tsung Tseng) | |
| dc.contributor.author | Kulvara Lapanan | en |
| dc.contributor.author | 張雨菲 | zh_TW |
| dc.date.accessioned | 2022-11-24T03:37:49Z | - |
| dc.date.available | 2021-08-18 | |
| dc.date.available | 2022-11-24T03:37:49Z | - |
| dc.date.copyright | 2021-08-18 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-07-29 | |
| dc.identifier.citation | Atlas, L. Y., Bolger, N., Lindquist, M. A., Wager, T. D. (2010). Brain mediators of predictive cue effects on perceived pain. J Neurosci, 30(39), 12964-12977. doi:10.1523/jneurosci.0057-10.2010 Bechara, A., Damasio, H., Damasio, A. R. (2000). Emotion, decision making and the orbitofrontal cortex. Cereb Cortex, 10(3), 295-307. doi:10.1093/cercor/10.3.295 Benedetti, F., Pollo, A., Lopiano, L., Lanotte, M., Vighetti, S., Rainero, I. (2003). Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses. J Neurosci, 23(10), 4315-4323. doi:10.1523/jneurosci.23-10-04315.2003 Casey, K. L. (1999). Forebrain mechanisms of nociception and pain: analysis through imaging. Proc Natl Acad Sci U S A, 96(14), 7668-7674. doi:10.1073/pnas.96.14.7668 Delgado, M. R., Jou, R. L., Phelps, E. A. (2011). Neural systems underlying aversive conditioning in humans with primary and secondary reinforcers. Front Neurosci, 5, 71. doi:10.3389/fnins.2011.00071 Delgado, M. R., Nearing, K. I., Ledoux, J. E., Phelps, E. A. (2008). Neural circuitry underlying the regulation of conditioned fear and its relation to extinction. Neuron, 59(5), 829-838. doi:10.1016/j.neuron.2008.06.029 Dörfel, D., Lamke, J. P., Hummel, F., Wagner, U., Erk, S., Walter, H. (2014). Common and differential neural networks of emotion regulation by Detachment, Reinterpretation, Distraction, and Expressive Suppression: a comparative fMRI investigation. Neuroimage, 101, 298-309. oi:10.1016/j.neuroimage.2014.06.051 Gross, J. J. (1998). Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. J Pers Soc Psychol, 74(1), 224-237. doi:10.1037//0022-3514.74.1.224 Kim, H., Somerville, L. H., Johnstone, T., Alexander, A. L., Whalen, P. J. (2003). Inverse amygdala and medial prefrontal cortex responses to surprised faces. Neuroreport, 14(18), 2317-2322. doi:10.1097/00001756-200312190-00006 Kim, S. H., Hamann, S. (2007). Neural correlates of positive and negative emotion regulation. J Cogn Neurosci, 19(5), 776-798. doi:10.1162/jocn.2007.19.5.776 Koyama, T., McHaffie, J. G., Laurienti, P. J., Coghill, R. C. (2005). The subjective experience of pain: where expectations become reality. Proc Natl Acad Sci U S A, 102(36), 12950-12955. doi:10.1073/pnas.0408576102 LaBar, K. S., LeDoux, J. E., Spencer, D. D., Phelps, E. A. (1995). Impaired fear conditioning following unilateral temporal lobectomy in humans. J Neurosci, 15(10), 6846-6855. doi:10.1523/jneurosci.15-10-06846.1995 Leknes, S., Berna, C., Lee, M. C., Snyder, G. D., Biele, G., Tracey, I. (2013). The importance of context: when relative relief renders pain pleasant. Pain, 154(3), 402-410. doi:10.1016/j.pain.2012.11.018 Lungu, O. V., Binenstock, M. M., Pline, M. A., Yeaton, J. R., Carey, J. R. (2007). Neural changes in control implementation of a continuous task. J Neurosci, 27(11), 3010-3016. doi:10.1523/jneurosci.5051-06.2007 McRae, K., Hughes, B., Chopra, S., Gabrieli, J. D., Gross, J. J., Ochsner, K. N. (2010). The neural bases of distraction and reappraisal. J Cogn Neurosci, 22(2), 248-262. doi:10.1162/jocn.2009.21243 Merskey, H. a. B., N. (1986). Classification of chronic pain. Descriptions of chronic pain syndromes and definitions of pain terms. Prepared by the International Association for the Study of Pain, Subcommittee on Taxonomy. Pain Suppl, 3, S1-226. Ochsner, K. N., Bunge, S. A., Gross, J. J., Gabrieli, J. D. (2002). Rethinking feelings: an FMRI study of the cognitive regulation of emotion. J Cogn Neurosci, 14(8), 1215-1229. doi:10.1162/089892902760807212 Ochsner, K. N., Gross, J. J. (2005). The cognitive control of emotion. Trends Cogn Sci, 9(5), 242-249. doi:10.1016/j.tics.2005.03.010 Ochsner, K. N., Knierim, K., Ludlow, D. H., Hanelin, J., Ramachandran, T., Glover, G., Mackey, S. C. (2004). Reflecting upon feelings: an fMRI study of neural systems supporting the attribution of emotion to self and other. J Cogn Neurosci, 16(10), 1746-1772. doi:10.1162/0898929042947829 Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D., Gross, J. J. (2004). For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. Neuroimage, 23(2), 483-499. doi:10.1016/j.neuroimage.2004.06.030 Peyron, R., García-Larrea, L., Grégoire, M. C., Costes, N., Convers, P., Lavenne, F., . . . Laurent, B. (1999). Haemodynamic brain responses to acute pain in humans: sensory and attentional networks. Brain, 122 ( Pt 9), 1765-1780. doi:10.1093/brain/122.9.1765 Peyron, R., Laurent, B., García-Larrea, L. (2000). Functional imaging of brain responses to pain. A review and meta-analysis (2000). Neurophysiol Clin, 30(5), 263-288. doi:10.1016/s0987-7053(00)00227-6 Picó-Pérez, M., Alemany-Navarro, M., Dunsmoor, J. E., Radua, J., Albajes-Eizagirre, A., Vervliet, B., . . . Fullana, M. A. (2019). Common and distinct neural correlates of fear extinction and cognitive reappraisal: A meta-analysis of fMRI studies. Neurosci Biobehav Rev, 104, 102-115. doi:10.1016/j.neubiorev.2019.06.029 Ploghaus, A., Narain, C., Beckmann, C. F., Clare, S., Bantick, S., Wise, R., . . . Tracey, I. (2001). Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci, 21(24), 9896-9903. doi:10.1523/jneurosci.21-24-09896.2001 Ploghaus, A., Tracey, I., Gati, J. S., Clare, S., Menon, R. S., Matthews, P. M., Rawlins, J. N. (1999). Dissociating pain from its anticipation in the human brain. Science, 284(5422), 1979-1981. doi:10.1126/science.284.5422.1979 Price, D. D., Milling, L. S., Kirsch, I., Duff, A., Montgomery, G. H., Nicholls, S. S. (1999). An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm. Pain, 83(2), 147-156. doi:10.1016/s0304-3959(99)00081-0 Sawamoto, N., Honda, M., Okada, T., Hanakawa, T., Kanda, M., Fukuyama, H., . . . Shibasaki, H. (2000). Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulate cortex and parietal operculum/posterior insula: an event-related functional magnetic resonance imaging study. J Neurosci, 20(19), 7438-7445. doi:10.1523/jneurosci.20-19-07438.2000 Shih, Y. W., Tsai, H. Y., Lin, F. S., Lin, Y. H., Chiang, C. Y., Lu, Z. L., Tseng, M. T. (2019). Effects of Positive and Negative Expectations on Human Pain Perception Engage Separate But Interrelated and Dependently Regulated Cerebral Mechanisms. J Neurosci, 39(7), 1261-1274. doi:10.1523/jneurosci.2154-18.2018 Tracey, I., Ploghaus, A., Gati, J. S., Clare, S., Smith, S., Menon, R. S., Matthews, P. M. (2002). Imaging attentional modulation of pain in the periaqueductal gray in humans. J Neurosci, 22(7), 2748-2752. doi:10.1523/jneurosci.22-07-02748.2002 Treede, R. D., Kenshalo, D. R., Gracely, R. H., Jones, A. K. (1999). The cortical representation of pain. Pain, 79(2-3), 105-111. doi:10.1016/s0304-3959(98)00184-5 Villemure, C., Bushnell, C. M. (2002). Cognitive modulation of pain: how do attention and emotion influence pain processing? Pain, 95(3), 195-199. doi:10.1016/s0304-3959(02)00007-6 Wood, K. H., Ver Hoef, L. W., Knight, D. C. (2014). The amygdala mediates the emotional modulation of threat-elicited skin conductance response. Emotion, 14(4), 693-700. doi:10.1037/a0036636 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/81235 | - |
| dc.description.abstract | 人類主要的感官經驗被認為是由預期與所接收到訊息互相交互作用而形成。儘管過去的研究皆指出，當大腦區域在調節疼痛時，感知功能與掌控情緒的大腦區域皆會被活化，例如眶額皮層（orbitofrontal cortex）和前扣帶皮層 (anterior cingulate cortex)。然而，到目前為止，情緒處理是否會影響疼痛調節仍不清楚。在本篇研究當中，我們採用功能性磁振造影（fMRI）來了解人類疼痛受到預期調節時扮演的角色。在本實驗中，我們使用視覺刺激以及情緒調節（重新評估）來操弄受試者的情緒。當實驗參與者預期到即將到來的疼痛刺激時，我們發現情緒調節策略能有效地減少負面和正面預期對痛覺調節的效應，且這兩種類型的預期效應包含不同的組成部分。我們發現負面預期包含情感和認知成分，而正面預期僅包含認知成分。當負面預期增痛的效果被情緒調節減少時，伴隨著右背前額葉皮質、右前扣帶皮質和左眶額皮質的活性減少，這表示這些區域可能構成負面預期的情感和認知成分。當正面預期減痛的效果被情緒調節減少時，伴隨著右背前額葉皮質活性增加，顯示此腦區可能構成正面預期的認知成分。這些實驗的結果顯示情緒對疼痛預期的作用在負面和正面的預期之間是不同的，增進了目前對人類疼痛認知調節的了解。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-24T03:37:49Z (GMT). No. of bitstreams: 1 U0001-2807202118105700.pdf: 1271888 bytes, checksum: 8f0a0919114091f65788468fb3719564 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 口試委員會審定書 i Acknowledgement ii 中文摘要 iii Abstract iv Table of Contents v List of Figures vii List of Tables viii Introduction 1 Materials and Methods 3 Participants 3 Pain stimulation 3 Procedure 4 Post-scanning rating 7 Physiological set-up and assessment 7 fMRI data acquisition 8 Analysis of fMRI data 8 Results 10 Behavioral results 10 Validation 10 Influence of expectations on pain 10 Influence of cognitive emotion regulation on the effects of expectations on pain 11 Emotion and cognitive ratings modulated by cognitive emotion regulation 12 Physiological assessment 13 Imaging results 13 Activations in afferent pain circuits 13 Brain activations associated with the modulation of expectations on pain 14 Modulation of cognitive emotion regulation on effects of pain expectancy 14 Discussion 16 Emotional and cognitive components of pain expectancy 16 Common brain activations underlie pain expectancy 16 Distinct neural responses between the effects of negative and positive expectations 17 References 19 | |
| dc.language.iso | en | |
| dc.subject | 功能性磁振造影 | zh_TW |
| dc.subject | 疼痛 | zh_TW |
| dc.subject | 情感 | zh_TW |
| dc.subject | 認知 | zh_TW |
| dc.subject | 期望 | zh_TW |
| dc.subject | fMRI | en |
| dc.subject | emotion | en |
| dc.subject | cognition | en |
| dc.subject | pain | en |
| dc.subject | expectation | en |
| dc.title | 探討情緒在預期影響痛覺之角色 | zh_TW |
| dc.title | Investigating the Role of Emotion in the Modulation of Expectations on Pain | en |
| dc.date.schoolyear | 109-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.advisor-orcid | 曾明宗(0000-0003-3763-9548) | |
| dc.contributor.oralexamcommittee | 吳恩賜 (Hsin-Tsai Liu),張立鴻(Chih-Yang Tseng) | |
| dc.subject.keyword | 疼痛,期望,情感,認知,功能性磁振造影, | zh_TW |
| dc.subject.keyword | pain,expectation,emotion,cognition,fMRI, | en |
| dc.relation.page | 40 | |
| dc.identifier.doi | 10.6342/NTU202101864 | |
| dc.rights.note | 同意授權(限校園內公開) | |
| dc.date.accepted | 2021-07-30 | |
| dc.contributor.author-college | 醫學院 | zh_TW |
| dc.contributor.author-dept | 腦與心智科學研究所 | zh_TW |
| 顯示於系所單位： | 腦與心智科學研究所 | |
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