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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 林信甫(Hsin-Fu Lin) | |
| dc.contributor.author | I-Chen Su | en |
| dc.contributor.author | 蘇羿蓁 | zh_TW |
| dc.date.accessioned | 2022-11-24T03:35:05Z | - |
| dc.date.available | 2021-08-10 | |
| dc.date.available | 2022-11-24T03:35:05Z | - |
| dc.date.copyright | 2021-08-10 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-08-04 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/81187 | - |
| dc.description.abstract | "背景:近年研究發現骨骼分泌之骨鈣素 (osteocalcin) 具有似荷爾蒙的功能，其中未羧 化骨鈣素 (undercarboxylated osteocalcin, ucOC) 可能與運動能力和動脈硬化有關。中高齡者 規律從事阻力訓練能預防骨質疏鬆和肌少症，不過有文獻指出阻力訓練對心血管系統會造成 負面的影響。目的:探討中老年人規律高強度阻力訓練介入後，對不同結構骨鈣素和血管硬 化指標與骨密度的影響，以及骨鈣素和血管硬化指標、骨密度是否具有相關性。方法:受試 者為 28 位無規律運動習慣的健康中老年人(年齡 64.0±5.8 歲，身高 164.5±8.4 公分，體重 64.5±11.2 公斤)，分為規律運動組 (N=14) 和控制組 (N=14)，進行 8 週，每週 3 次，80% 1RM (one repetition maximum, 1RM) 之全身高強度機械式阻力訓練，測量訓練前、後及停止 訓練 4 週後的骨鈣素濃度、血管硬化指標及骨密度。結果:高強度阻力訓練介入對血管硬化 指標肱踝脈波傳導速度(brachial-ankle pulse wave velocity, baPWV)、頸股脈波傳導速度 (carotid-femoral PWV, cfPWV)、頸動脈脈波傳導速度(local pulse wave velocity, local PWV) 和 血清總骨鈣素(total osteocalcin, tOC)、ucOC 濃度及骨密度皆無顯著影響;tOC、ucOC 和血 管硬化指標也不具有相關性。不過在骨密度變化量方面，運動組整體和控制組有顯著差異 (p=0.01)，運動組在訓練後和四周停止訓練的變化量皆是些微增加 (訓練後 0.005±0.012 g/cm2，停止訓練 0.006±0.011 g/cm2)，而控制組則皆是些微下降 (訓練後−0.004±0.009 g/cm2，停止訓練−0.005±0.008 g/cm2);而 tOC 和骨密度在訓練後和停止訓練 2 個時間點， 呈現顯著負相關 (訓練後 r = −0.48，p=0.01;停止訓練 r = −0.43，p=0.02)。結論:健康中老 年人規律進行高強度阻力訓練 8 週後，動脈硬化指標 PWV、骨鈣素和骨密度皆未有顯著改 變，不過可能有維持骨密度的效果。中老年人從事短期高強度阻力訓練，並未影響骨鈣素及 動脈硬化指標，但對骨質密度可能有正面影響;骨鈣素和動脈硬化指標及骨密度變化之間的 相關性，未來還需更多研究證實。" | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-24T03:35:05Z (GMT). No. of bitstreams: 1 U0001-0308202112150500.pdf: 2015146 bytes, checksum: af2b6902461b717da50e1a438b577287 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 口試委員會審定書.............................................................................................i 中文摘要.........................................................................................................ii 英文摘要.........................................................................................................iii 目錄...............................................................................................................iv 圖次...............................................................................................................vi 表次............................................................................................................vii 第壹章 緒論................................................................................................... 1 第一節 研究背景....................................................................................... 4 第二節 研究目的.......................................................................................10 第三節 研究假設.......................................................................................10 第四節 名詞操作型定義..............................................................................11 第五節 研究範圍與限制..............................................................................11 第六節 研究重要性....................................................................................12 第貳章 研究方法.............................................................................................13 第一節 研究對象.......................................................................................13 第二節 研究設計.......................................................................................14 第三節 實驗測量方法.................................................................................17 第四節 統計方法.......................................................................................19 第參章 研究結果.............................................................................................20 第一節 受試者基本資料..............................................................................20 第二節 血壓及血管硬化指標化.....................................................................21 第三節 骨鈣素濃度變化..............................................................................23 第四節 骨密度變化....................................................................................27 第五節 不訓練 4 週後指標差異.....................................................................29 第肆章 討論...................................................................................................30 第一節 阻力訓練介入對血管硬化的影響.........................................................30 第二節 阻力訓練介入對骨鈣素濃度的影響......................................................32 第三節 血管硬化與骨鈣素的相關性...............................................................34 第四節 阻力訓練介入對骨密度變化的影響......................................................37 第五節 骨鈣素和骨密度的關聯性..................................................................38 第六節 結論與建議....................................................................................40 參考文獻.........................................................................................................41 附錄 附錄一 tOC 和 ucOC 停止訓練的變化量.........................................................53 附錄二 骨密度變化量.................................................................................54 附錄三 肌肉量相關分析..............................................................................55 | |
| dc.language.iso | zh-TW | |
| dc.subject | 脈波傳導速度 | zh_TW |
| dc.subject | 未羧化骨鈣素 | zh_TW |
| dc.subject | 動脈硬化 | zh_TW |
| dc.subject | 高強度阻力訓練 | zh_TW |
| dc.subject | 骨密度 | zh_TW |
| dc.subject | atherosclerosis | en |
| dc.subject | high-intensity resistance training | en |
| dc.subject | bone mineral density | en |
| dc.subject | undercarboxylated osteocalcin | en |
| dc.subject | pulse wave velocity | en |
| dc.title | 中老年人高強度阻力運動訓練與血清骨鈣素變化、動脈硬化指標及骨密度變化之探討 | zh_TW |
| dc.title | "The Impact of High-intensity Resistance Training on Serum Osteocalcin, Arterial Stiffness and Bone Mineral Density in Middle-aged to Older Adults" | en |
| dc.date.schoolyear | 109-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 王順正(Hsin-Tsai Liu),林原佑(Chih-Yang Tseng) | |
| dc.subject.keyword | 未羧化骨鈣素,動脈硬化,高強度阻力訓練,骨密度,脈波傳導速度, | zh_TW |
| dc.subject.keyword | undercarboxylated osteocalcin,atherosclerosis,high-intensity resistance training,bone mineral density,pulse wave velocity, | en |
| dc.relation.page | 55 | |
| dc.identifier.doi | 10.6342/NTU202102034 | |
| dc.rights.note | 同意授權(限校園內公開) | |
| dc.date.accepted | 2021-08-05 | |
| dc.contributor.author-dept | 共同教育中心 | zh_TW |
| dc.contributor.author-dept | 運動設施與健康管理碩士學位學程 | zh_TW |
| 顯示於系所單位： | 運動設施與健康管理碩士學位學程 | |
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