請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80958完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 郭育良 | zh_TW |
| dc.contributor.advisor | Yue Leon Guo | en |
| dc.contributor.author | 施屏 | zh_TW |
| dc.contributor.author | Ping Shih | en |
| dc.date.accessioned | 2022-11-24T03:23:39Z | - |
| dc.date.available | 2025-09-01 | - |
| dc.date.copyright | 2021-10-01 | - |
| dc.date.issued | 2021 | - |
| dc.date.submitted | 2002-01-01 | - |
| dc.identifier.citation | Aasheim, V., Waldenström, U., Hjelmstedt, A., Rasmussen, S., Pettersson, H., & Schytt, E. (2012). Associations between advanced maternal age and psychological distress in primiparous women, from early pregnancy to 18 months postpartum. Bjog, 119(9), 1108-1116. doi:10.1111/j.1471-0528.2012.03411.x Akincigil, A., Munch, S., & Niemczyk, K. C. (2010). Predictors of Maternal Depression in the First Year Postpartum: Marital Status and Mediating Role of Relationship Quality. Social Work in Health Care, 49(3), 227-244. doi:10.1080/00981380903213055 Allen, J. L., Liu, X., Weston, D., Prince, L., Oberdörster, G., Finkelstein, J. N., . . . Cory-Slechta, D. A. (2014). Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation. Toxicological sciences : an official journal of the Society of Toxicology, 140(1), 160-178. doi:10.1093/toxsci/kfu059 American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR): AmericanPsychiatricAssociation. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders. Arlington, VA: American Psychiatric Association. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders : DSM-IV: Fourth edition. Washington, DC : American Psychiatric Association, 1994. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, 4th Edition, Text Revision (DSM-IV-TR). Washington, DC : American Psychiatric Association. Babenko, O., Kovalchuk, I., & Metz, G. A. (2015). Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health. Neurosci Biobehav Rev, 48, 70-91. doi:10.1016/j.neubiorev.2014.11.013 Banerjee, T. D., Middleton, F., & Faraone, S. V. (2007). Environmental risk factors for attention-deficit hyperactivity disorder. Acta Paediatr, 96(9), 1269-1274. doi:10.1111/j.1651-2227.2007.00430.x Biederman, J., & Faraone, S. V. (2005). Attention-deficit hyperactivity disorder. Lancet, 366(9481), 237-248. doi:10.1016/s0140-6736(05)66915-2 Block, M. L., & Calderón-Garcidueñas, L. (2009). Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences, 32(9), 506-516. doi:https://doi.org/10.1016/j.tins.2009.05.009 Boath, E. H., Pryce, A. J., & Cox, J. L. (1998). Postnatal depression: The impact on the family. Journal of Reproductive and Infant Psychology, 16(2-3), 199-203. doi:10.1080/02646839808404568 Brockmeyer, S., & D'Angiulli, A. (2016). How air pollution alters brain development: the role of neuroinflammation. Translational neuroscience, 7(1), 24-30. doi:10.1515/tnsci-2016-0005 Brummelte, S., & Galea, L. A. M. (2016). Postpartum depression: Etiology, treatment and consequences for maternal care. Hormones and Behavior, 77, 153-166. doi:https://doi.org/10.1016/j.yhbeh.2015.08.008 Calderón-Garcidueñas, L., Mora-Tiscareño, A., Ontiveros, E., Gómez-Garza, G., Barragán-Mejía, G., Broadway, J., . . . Engle, R. W. (2008). Air pollution, cognitive deficits and brain abnormalities: A pilot study with children and dogs. Brain and Cognition, 68(2), 117-127. doi:https://doi.org/10.1016/j.bandc.2008.04.008 Chang, L.-Y., Lin, Y.-H., Lin, S.-J., & Chiang, T.-l. (2021). Cohort Profile: Taiwan Birth Cohort Study (TBCS). International Journal of Epidemiology. doi:10.1093/ije/dyab048 Chen, M. H., Lan, W. H., Bai, Y. M., Huang, K. L., Su, T. P., Tsai, S. J., . . . Hsu, J. W. (2016). Influence of Relative Age on Diagnosis and Treatment of Attention-Deficit Hyperactivity Disorder in Taiwanese Children. J Pediatr, 172, 162-167.e161. doi:10.1016/j.jpeds.2016.02.012 Chen, N.-T., Lin, P.-H., & Guo, Y.-L. L. (2019). Long-term exposure to high temperature associated with the incidence of major depressive disorder. Science of The Total Environment, 659, 1016-1020. doi:https://doi.org/10.1016/j.scitotenv.2018.12.434 Chen, T.-H., Hsu, Y.-C., Zeng, Y.-T., Candice Lung, S.-C., Su, H.-J., Chao, H. J., & Wu, C.-D. (2020). A hybrid kriging/land-use regression model with Asian culture-specific sources to assess NO2 spatial-temporal variations. Environmental Pollution, 259, 113875. doi:https://doi.org/10.1016/j.envpol.2019.113875 Chiang, M. C. (2015). Effects of Maternal Stress During Pregnancy on Birth Outcome and Stress-related Hormones. Pediatr Neonatol, 56(6), 365-366. doi:10.1016/j.pedneo.2015.08.004 Chiu, Y.-H. M., Hsu, H.-H. L., Coull, B. A., Bellinger, D. C., Kloog, I., Schwartz, J., . . . Wright, R. J. (2016). Prenatal particulate air pollution and neurodevelopment in urban children: Examining sensitive windows and sex-specific associations. Environment International, 87, 56-65. doi:https://doi.org/10.1016/j.envint.2015.11.010 Class, Q. A., Abel, K. M., Khashan, A. S., Rickert, M. E., Dalman, C., Larsson, H., . . . D'Onofrio, B. M. (2014). Offspring psychopathology following preconception, prenatal and postnatal maternal bereavement stress. Psychol Med, 44(1), 71-84. doi:10.1017/s0033291713000780 Clifford, A., Lang, L., Chen, R., Anstey, K. J., & Seaton, A. (2016). Exposure to air pollution and cognitive functioning across the life course--A systematic literature review. Environ Res, 147, 383-398. doi:10.1016/j.envres.2016.01.018 Coussons-Read, M. E., Okun, M. L., & Nettles, C. D. (2007). Psychosocial stress increases inflammatory markers and alters cytokine production across pregnancy. Brain Behav Immun, 21(3), 343-350. doi:10.1016/j.bbi.2006.08.006 Coussons-Read, M. E., Okun, M. L., Schmitt, M. P., & Giese, S. (2005). Prenatal stress alters cytokine levels in a manner that may endanger human pregnancy. Psychosom Med, 67(4), 625-631. doi:10.1097/01.psy.0000170331.74960.ad Cowell, W. J., Bellinger, D. C., Coull, B. A., Gennings, C., Wright, R. O., & Wright, R. J. (2015). Associations between prenatal exposure to black carbon and memory domains in urban children: modification by sex and prenatal stress. PLoS One, 10(11). doi:10.1371/journal.pone.0142492 Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008). From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Reviews Neuroscience, 9(1), 46-56. doi:10.1038/nrn2297 Dawson, M., Ph. D, Ted M, & Dawson, P. D., Valina L. (1996). Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system. Annual review of medicine, 47(1), 219-227. Egger, H. L., Kondo, D., & Angold, A. (2006). The Epidemiology and Diagnostic Issues in Preschool Attention-Deficit/Hyperactivity Disorder: A Review. Infants & Young Children, 19(2), 109-122. doi:10.1097/00001163-200604000-00004 Fan, S.-J., Bloom, M., Zhao, T., Shi, T.-X., Feng, W.-R., Sun, Y., . . . Dong, G.-H. (2020). Ambient air pollution and depression: A systematic review with meta-analysis up to 2019. Science of The Total Environment, 701, 134721. doi:10.1016/j.scitotenv.2019.134721 Flanigan, C., Sheikh, A., DunnGalvin, A., Brew, B. K., Almqvist, C., & Nwaru, B. I. (2018). Prenatal maternal psychosocial stress and offspring's asthma and allergic disease: A systematic review and meta-analysis. Clin Exp Allergy, 48(4), 403-414. doi:10.1111/cea.13091 Fonken, L. K., Xu, X., Weil, Z. M., Chen, G., Sun, Q., Rajagopalan, S., & Nelson, R. J. (2011). Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology. Mol Psychiatry, 16(10), 987-995, 973. doi:10.1038/mp.2011.76 Forns, J., Sunyer, J., Garcia-Esteban, R., Porta, D., Ghassabian, A., Giorgis-Allemand, L., . . . Guxens, M. (2018). Air Pollution Exposure During Pregnancy and Symptoms of Attention Deficit and Hyperactivity Disorder in Children in Europe. Epidemiology, 29(5), 618-626. doi:10.1097/ede.0000000000000874 Fuertes, E., Standl, M., Forns, J., Berdel, D., Garcia-Aymerich, J., Markevych, I., . . . Heinrich, J. (2016). Traffic-related air pollution and hyperactivity/inattention, dyslexia and dyscalculia in adolescents of the German GINIplus and LISAplus birth cohorts. Environ Int, 97, 85-92. doi:https://doi.org/10.1016/j.envint.2016.10.017 Galea, S., & Tracy, M. (2007). Participation rates in epidemiologic studies. Ann Epidemiol, 17(9), 643-653. doi:10.1016/j.annepidem.2007.03.013 Gallo, E. F., & Posner, J. (2016). Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms. Lancet Psychiatry, 3(6), 555-567. doi:10.1016/S2215-0366(16)00096-1 Gan, Z., Li, Y., Xie, D., Shao, C., Yang, F., Shen, Y., . . . Zhang, J. (2012). The impact of educational status on the clinical features of major depressive disorder among Chinese women. Journal of Affective Disorders, 136(3), 988-992. doi:https://doi.org/10.1016/j.jad.2011.06.046 Gau, S. S., Chong, M. Y., Chen, T. H., & Cheng, A. T. (2005). A 3-year panel study of mental disorders among adolescents in Taiwan. Am J Psychiatry, 162(7), 1344-1350. doi:10.1176/appi.ajp.162.7.1344 Gershon, J. (2002). A meta-analytic review of gender differences in ADHD. J Atten Disord, 5(3), 143-154. doi:10.1177/108705470200500302 Ginsberg, Y., Khatib, N., Weiner, Z., & Beloosesky, R. (2017). Maternal Inflammation, Fetal Brain Implications and Suggested Neuroprotection: A Summary of 10 Years of Research in Animal Models. Rambam Maimonides Med J, 8(2). doi:10.5041/rmmj.10305 Gitau, R., Cameron, A., Fisk, N. M., & Glover, V. (1998). Fetal exposure to maternal cortisol. Lancet, 352(9129), 707-708. doi:10.1016/s0140-6736(05)60824-0 Glynn, L. M., Davis, E. P., & Sandman, C. A. (2013). New insights into the role of perinatal HPA-axis dysregulation in postpartum depression. Neuropeptides, 47(6), 363-370. doi:https://doi.org/10.1016/j.npep.2013.10.007 Goasdoue, K., Miller, S. M., Colditz, P. B., & Bjorkman, S. T. (2017). Review: The blood-brain barrier; protecting the developing fetal brain. Placenta, 54, 111-116. doi:10.1016/j.placenta.2016.12.005 Gomez-Sanchez, E. P. (2014). Brain mineralocorticoid receptors in cognition and cardiovascular homeostasis. Steroids, 91, 20-31. doi:10.1016/j.steroids.2014.08.014 Gong, T., Almqvist, C., Bölte, S., Lichtenstein, P., Anckarsäter, H., Lind, T., . . . Pershagen, G. (2014). Exposure to Air Pollution From Traffic and Neurodevelopmental Disorders in Swedish Twins. Twin Research and Human Genetics, 17(6), 553-562. doi:10.1017/thg.2014.58 Goyal, D., Gay, C., & Lee, K. A. (2010). How much does low socioeconomic status increase the risk of prenatal and postpartum depressive symptoms in first-time mothers? Women's health issues : official publication of the Jacobs Institute of Women's Health, 20(2), 96-104. doi:10.1016/j.whi.2009.11.003 Goyal, D., Gay, C., Torres, R., & Lee, K. (2018). Shortening day length: a potential risk factor for perinatal depression. J Behav Med, 41(5), 690-702. doi:10.1007/s10865-018-9971-2 Grandjean, P., & Landrigan, P. J. (2014). Neurobehavioural effects of developmental toxicity. Lancet Neurol, 13(3), 330-338. doi:10.1016/s1474-4422(13)70278-3 Grizenko, N., Fortier, M. E., Gaudreau-Simard, M., Jolicoeur, C., & Joober, R. (2015). The Effect of Maternal Stress during Pregnancy on IQ and ADHD Symptomatology. J Can Acad Child Adolesc Psychiatry, 24(2), 92-99. Guxens, M., Lubczyńska, M. J., Muetzel, R. L., Dalmau-Bueno, A., Jaddoe, V. W. V., Hoek, G., . . . El Marroun, H. (2018). Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children. Biological Psychiatry, 84(4), 295-303. doi:https://doi.org/10.1016/j.biopsych.2018.01.016 Hahad, O., Lelieveld, J., Birklein, F., Lieb, K., Daiber, A., & Munzel, T. (2020). Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress. International Journal of Molecular Sciences. doi:10.3390/ijms21124306 Haynes, R. B., Sackett, D. L., Richardson, W. S., Rosenberg, W., & Langley, G. R. (1997). Evidence-based medicine: How to practice & teach EBM. Canadian Medical Association. Journal, 157(6), 788. Heh, S. S. (2001). Validation of the Chinese version of the Edinburgh Postnatal Depression Scale: detecting postnatal depression in Taiwanese women. [中文版愛丁堡産後憂鬱量表之效度評估－台灣婦女産後憂鬱之測定]. Hu Li Yan Jiu, 9(2), 105-113. doi:10.7081/NR.200104.0105 Heinrichs, M., Neumann, I., & Ehlert, U. (2002). Lactation and Stress: Protective Effects of Breast-feeding in Humans. Stress, 5(3), 195-203. doi:10.1080/1025389021000010530 Hjortebjerg, D., Andersen, A. M. N., Christensen, J. S., Ketzel, M., Raaschou-Nielsen, O., Sunyer, J., . . . Sørensen, M. (2016). Exposure to Road Traffic Noise and Behavioral Problems in 7-Year-Old Children: A Cohort Study. Environmental Health Perspectives, 124(2), 228-234. doi:doi:10.1289/ehp.1409430 Hou, P.-c., Tu, S.-H., Liao, P., Hung, Y.-T., & Chang, Y.-H. (2008). The typology of townships in Taiwan: the analysis of sampling stratification of the 2005–2006 “Taiwan Social Change Survey”. [台灣鄉鎮市區類型之研究：「台灣社會變遷基本調查」第五期計畫之抽樣分層效果分析]. Survey Research—Method and Application, 23(1), 7-32. doi:10.7014/TCYCFFYYY.200804.0007 Hou, P. H., Lin, C. C., Chi, C. S., & Chan, C. H. (2003). Prevalence of ADHD in an elementary school sample of Taiwanese children in Taichung. [臺中地區某國小低年級學童注意力不足過動症候群盛行率初探]. 15, 163-167. doi:10.6440/TZUCMJ.200306.0163 Huang, C. C., Wen, H. J., Chen, P. C., Chiang, T. L., Lin, S. J., & Guo, Y. L. (2015). Prenatal air pollutant exposure and occurrence of atopic dermatitis. Br J Dermatol, 173(4), 981-988. doi:10.1111/bjd.14039 Huang, C. L., Chu, C. C., Cheng, T. J., & Weng, S. F. (2014). Epidemiology of treated attention-deficit/hyperactivity disorder (ADHD) across the lifespan in Taiwan: a nationwide population-based longitudinal study. PLoS One, 9(4), e95014. doi:10.1371/journal.pone.0095014 Huang, Y. C., & Mathers, N. (2001). Postnatal depression - Biological or cultural? A comparative study of postnatal women in the UK and Taiwan. Journal of Advanced Nursing, 33, 279-287. doi:10.1046/j.1365-2648.2001.01664.x Hunter, C. M., & Figueiro, M. G. (2017). Measuring light at night and melatonin levels in shift workers: a review of the literature. Biological research for nursing, 19(4), 365-374. doi:10.1177/1099800417714069 Hurley, L. L., & Tizabi, Y. (2013). Neuroinflammation, Neurodegeneration, and Depression. Neurotoxicity Research, 23(2), 131-144. doi:10.1007/s12640-012-9348-1 Ikeda, S., Tamaoki, H., Akahane, M., & Nebashi, Y. (1984). Effects of Ritodrine Hydrochloride, a Beta2-Adrenoceptor Stimulant, on Uterine Motilities in Late Pregnancy. Japanese Journal of Pharmacology, 35(3), 319-326. doi:https://doi.org/10.1254/jjp.35.319 Iwata, H., Mori, E., Sakajo, A., Aoki, K., Maehara, K., & Tamakoshi, K. (2016). Prevalence of postpartum depressive symptoms during the first 6 months postpartum: Association with maternal age and parity. Journal of Affective Disorders, 203, 227-232. doi:https://doi.org/10.1016/j.jad.2016.06.002 Jensen Peña, C., Monk, C., & Champagne, F. A. (2012). Epigenetic Effects of Prenatal Stress on 11β-Hydroxysteroid Dehydrogenase-2 in the Placenta and Fetal Brain. PLoS One, 7(6), e39791. doi:10.1371/journal.pone.0039791 Jo, S.-J., Yim, H. W., Bang, M. H., Lee, M. O., Jun, T.-Y., Choi, J.-S., . . . Park, Y.-M. (2011). The Association between Economic Status and Depressive Symptoms: An Individual and Community Level Approach. Psychiatry Investig, 8(3), 194-200. doi:10.4306/pi.2011.8.3.194 Jolley, S. N., Elmore, S., Barnard, K. E., & Carr, D. B. (2007). Dysregulation of the hypothalamic-pituitary-adrenal axis in postpartum depression. Biol Res Nurs, 8(3), 210-222. doi:10.1177/1099800406294598 Jui-Fen Rachel Lu, H.-M. T., Yih-Jian Tsai. (2003). Assessment of health-related quality of life in Taiwan (I): development and psychometric testing of SF-36 Taiwan version. [國人生活品質評量(Ⅰ)：SF-36台灣版的發展及心理計量特質分析]. Taiwan J Public Health, 22(6), 501-511. doi:10.6288/TJPH2003-22-06-09 Kalisa, E., Fadlallah, S., Amani, M., Nahayo, L., & Habiyaremye, G. (2018). Temperature and air pollution relationship during heatwaves in Birmingham, UK. Sustainable Cities and Society, 43, 111-120. doi:https://doi.org/10.1016/j.scs.2018.08.033 Kim, H. W., Cho, S. C., Kim, B. N., Kim, J. W., Shin, M. S., & Kim, Y. (2009). Perinatal and familial risk factors are associated with full syndrome and subthreshold attention-deficit hyperactivity disorder in a korean community sample. Psychiatry Investig, 6(4), 278-285. doi:10.4306/pi.2009.6.4.278 Kingsbury, M., Weeks, M., MacKinnon, N., Evans, J., Mahedy, L., Dykxhoorn, J., & Colman, I. (2016). Stressful Life Events During Pregnancy and Offspring Depression: Evidence From a Prospective Cohort Study. J Am Acad Child Adolesc Psychiatry, 55(8), 709-716.e702. doi:10.1016/j.jaac.2016.05.014 Korhonen, R., Lahti, A., Kankaanranta, H., & Moilanen, E. (2005). Nitric oxide production and signaling in inflammation. Curr Drug Targets Inflamm Allergy, 4(4), 471-479. doi:10.2174/1568010054526359 Lahey, B. B., Pelham, W. E., Loney, J., Lee, S. S., & Willcutt, E. (2005). Instability of the DSM-IV Subtypes of ADHD from preschool through elementary school. Arch Gen Psychiatry, 62(8), 896-902. doi:10.1001/archpsyc.62.8.896 Lau, Y. (2013). The effect of maternal stress and health-related quality of life on birth outcomes among Macao Chinese pregnant women. J Perinat Neonatal Nurs, 27(1), 14-24. doi:10.1097/JPN.0b013e31824473b9 Layton, T. J., Barnett, M. L., Hicks, T. R., & Jena, A. B. (2018). Attention Deficit–Hyperactivity Disorder and Month of School Enrollment. New England Journal of Medicine, 379(22), 2122-2130. doi:10.1056/NEJMoa1806828 Levesque, S., Taetzsch, T., Lull, M. E., Kodavanti, U., Stadler, K., Wagner, A., . . . Block, M. L. (2011). Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity. Environmental Health Perspectives, 119(8), 1149-1155. doi:doi:10.1289/ehp.1002986 Li-Yu Hung, Y.-N. C., Yu-Wen Chang, Ying-Ru Meng. (2001). The final report for educational placement and counseling for children with ADHD in Taiwan. A proposal from Ministry of Education, Taiwan. [注意力缺陷過動症學生發現與安置輔導工作─第三年期末報告。（教育部特殊教育工作小組委託專案) ]. Lin, P.-Y., Chiu, T.-H., Ho, M., Pei-Chen Chang, J., Hui-Chih Chang, C., & Su, K.-P. (2019). Major depressive episodes during pregnancy and after childbirth: A prospective longitudinal study in Taiwan. Journal of the Formosan Medical Association, 118(11), 1551-1559. doi:https://doi.org/10.1016/j.jfma.2019.03.003 Lin, Y., Zhou, L., Xu, J., Luo, Z., Kan, H., Zhang, J., . . . Zhang, J. (2017). The impacts of air pollution on maternal stress during pregnancy. Scientific reports, 7, 40956-40956. doi:10.1038/srep40956 Liu, Q., Wang, W., Gu, X., Deng, F., Wang, X., Lin, H., . . . Wu, S. (2021). Association between particulate matter air pollution and risk of depression and suicide: a systematic review and meta-analysis. Environ Sci Pollut Res Int, 28(8), 9029-9049. doi:10.1007/s11356-021-12357-3 Mancuso, C., Navarra, P., & Preziosi, P. (2010). Roles of nitric oxide, carbon monoxide, and hydrogen sulfide in the regulation of the hypothalamic–pituitary–adrenal axis. Journal of Neurochemistry, 113(3), 563-575. doi:10.1111/j.1471-4159.2010.06606.x Manning, J. R., Bailey, M. A., Soares, D. C., Dunbar, D. R., & Mullins, J. J. (2010). In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence. Physiol Genomics, 42(3), 319-330. doi:10.1152/physiolgenomics.00053.2010 McMahon, C. A., Barnett, B., Kowalenko, N. M., & Tennant, C. C. (2006). Maternal attachment state of mind moderates the impact of postnatal depression on infant attachment. Journal of Child Psychology and Psychiatry and Allied Disciplines, 47(7), 660-669. doi:10.1111/j.1469-7610.2005.01547.x Min, J.-y., & Min, K.-b. (2017). Exposure to ambient PM10 and NO2 and the incidence of attention-deficit hyperactivity disorder in childhood. Environment International, 99, 221-227. doi:https://doi.org/10.1016/j.envint.2016.11.022 Monk, C., Feng, T., Lee, S., Krupska, I., Champagne, F. A., & Tycko, B. (2016). Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior. Am J Psychiatry, 173(7), 705-713. doi:10.1176/appi.ajp.2015.15091171 Mortamais, M., Pujol, J., Martínez-Vilavella, G., Fenoll, R., Reynes, C., Sabatier, R., . . . Sunyer, J. (2019). Effects of prenatal exposure to particulate matter air pollution on corpus callosum and behavioral problems in children. Environ Res, 178, 108734. doi:https://doi.org/10.1016/j.envres.2019.108734 Moura, D., Canavarro, M. C., & Figueiredo-Braga, M. (2016). Oxytocin and depression in the perinatal period—a systematic review. Archives of Women's Mental Health, 19(4), 561-570. doi:10.1007/s00737-016-0643-3 Mukaka, M. M. (2012). Statistics corner: A guide to appropriate use of correlation coefficient in medical research. Malawi medical journal : the journal of Medical Association of Malawi, 24(3), 69-71. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/PMC3576830/ Niedzwiecki, M. M., Rosa, M. J., Solano-González, M., Kloog, I., Just, A. C., Martínez-Medina, S., . . . Wright, R. J. (2020). Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City. Environment International, 134, 105325. doi:https://doi.org/10.1016/j.envint.2019.105325 Norhayati, M. N., Nik Hazlina, N. H., Asrenee, A. R., & Wan Emilin, W. M. A. (2015). Magnitude and risk factors for postpartum symptoms: A literature review. Journal of Affective Disorders, 175, 34-52. doi:https://doi.org/10.1016/j.jad.2014.12.041 Novik, T. S., Hervas, A., Ralston, S. J., Dalsgaard, S., Rodrigues Pereira, R., & Lorenzo, M. J. (2006). Influence of gender on attention-deficit/hyperactivity disorder in Europe--ADORE. Eur Child Adolesc Psychiatry, 15 Suppl 1, I15-24. doi:10.1007/s00787-006-1003-z O'Hara, M. W., & McCabe, J. E. (2013). Postpartum depression: current status and future directions. Annu Rev Clin Psychol, 9, 379-407. doi:10.1146/annurev-clinpsy-050212-185612 Okano, L., Ji, Y., Riley, A. W., & Wang, X. (2018). Maternal psychosocial stress and children's ADHD diagnosis: a prospective birth cohort study. J Psychosom Obstet Gynaecol, 1-9. doi:10.1080/0167482x.2018.1468434 Okano, L., Ji, Y., Riley, A. W., & Wang, X. (2019). Maternal psychosocial stress and children's ADHD diagnosis: a prospective birth cohort study. J Psychosom Obstet Gynaecol, 40(3), 217-225. doi:10.1080/0167482x.2018.1468434 Okutomi, T., Nomoto, K., Nakamura, K., & Goto, F. (1997). Nitric oxide metabolite in pregnant women before and after delivery. Acta Obstet Gynecol Scand, 76(3), 222-226. Oudin, A., Frondelius, K., Haglund, N., Källén, K., Forsberg, B., Gustafsson, P., & Malmqvist, E. (2019). Prenatal exposure to air pollution as a potential risk factor for autism and ADHD. Environment International, 133, 105149. doi:https://doi.org/10.1016/j.envint.2019.105149 Owusu Darkwa, E., Djagbletey, R., Sottie, D., Owoo, C., Vanderpuye, N. M., Essuman, R., & Aryee, G. (2018). Serum nitric oxide levels in healthy pregnant women: a case- control study in a tertiary facility in Ghana. Maternal health, neonatology and perinatology, 4, 3-3. doi:10.1186/s40748-017-0072-y Payne, J. L., & Maguire, J. (2019). Pathophysiological mechanisms implicated in postpartum depression. Frontiers in Neuroendocrinology, 52, 165-180. doi:https://doi.org/10.1016/j.yfrne.2018.12.001 Perera, F. P., Chang, H. W., Tang, D., Roen, E. L., Herbstman, J., Margolis, A., . . . Rauh, V. (2014). Early-life exposure to polycyclic aromatic hydrocarbons and ADHD behavior problems. PLoS One, 9(11), e111670. doi:10.1371/journal.pone.0111670 Polanczyk, G., de Lima, M. S., Horta, B. L., Biederman, J., & Rohde, L. A. (2007). The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry, 164(6), 942-948. doi:10.1176/ajp.2007.164.6.942 Pope, C. J., & Mazmanian, D. (2016). Breastfeeding and Postpartum Depression: An Overview and Methodological Recommendations for Future Research. Depression research and treatment, 2016, 4765310-4765310. doi:10.1155/2016/4765310 Pulatova, M., Sharygin, V., Rikhireva, G., Mitrokhin, Y. I., & Todorov, I. (2006). The mechanisms of nitric oxide production from exogenous and endogenous NO-donating compounds in cells of higher animals and the influence of nitric oxide on deoxyribonucleotide and DNA synthesis. Biology Bulletin, 33(5), 441-456. doi:https://doi.org/10.1134/S1062359006050049 Racicot, K., Kwon, J. Y., Aldo, P., Silasi, M., & Mor, G. (2014). Understanding the complexity of the immune system during pregnancy. Am J Reprod Immunol, 72(2), 107-116. doi:10.1111/aji.12289 Reimelt, C., Wolff, N., Holling, H., Mogwitz, S., Ehrlich, S., Martini, J., & Roessner, V. (2018). Siblings and Birth Order-Are They Important for the Occurrence of ADHD? J Atten Disord, 1087054718770020. doi:10.1177/1087054718770020 Reuter, M., Markett, S., Melchers, M., & Montag, C. (2012). Interaction of the cholinergic system and the hypothalamic-pituitary-adrenal axis as a risk factor for depression: evidence from a genetic association study. Neuroreport, 23(12), 717-720. doi:10.1097/WNR.0b013e32835671ba Risom, L., Møller, P., & Loft, S. (2005). Oxidative stress-induced DNA damage by particulate air pollution. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 592(1), 119-137. doi:https://doi.org/10.1016/j.mrfmmm.2005.06.012 Rodriguez, A., & Bohlin, G. (2005). Are maternal smoking and stress during pregnancy related to ADHD symptoms in children? J Child Psychol Psychiatry, 46(3), 246-254. doi:10.1111/j.1469-7610.2004.00359.x Ronald, A., Pennell, C. E., & Whitehouse, A. J. O. (2011). Prenatal Maternal Stress Associated with ADHD and Autistic Traits in early Childhood. Frontiers in psychology, 1, 223-223. doi:10.3389/fpsyg.2010.00223 Rumana, H. S., Sharma, R. C., Beniwal, V., & Sharma, A. K. (2014). A retrospective approach to assess human health risks associated with growing air pollution in urbanized area of Thar Desert, western Rajasthan, India. J Environ Health Sci Eng, 12(1), 23. doi:10.1186/2052-336x-12-23 Russell, A. E., Ford, T., Williams, R., & Russell, G. (2016). The Association Between Socioeconomic Disadvantage and Attention Deficit/Hyperactivity Disorder (ADHD): A Systematic Review. Child Psychiatry Hum Dev, 47(3), 440-458. doi:10.1007/s10578-015-0578-3 Rylander, C., Odland, J. Ø., & Sandanger, T. M. (2013). Climate change and the potential effects on maternal and pregnancy outcomes: an assessment of the most vulnerable--the mother, fetus, and newborn child. Global health action, 6, 19538-19538. doi:10.3402/gha.v6i0.19538 Sappenfield, E., Jamieson, D. J., & Kourtis, A. P. (2013). Pregnancy and susceptibility to infectious diseases. Infect Dis Obstet Gynecol, 2013, 752852. doi:10.1155/2013/752852 Sayal, K., Chudal, R., Hinkka-Yli-Salomaki, S., Joelsson, P., & Sourander, A. (2017). Relative age within the school year and diagnosis of attention-deficit hyperactivity disorder: a nationwide population-based study. Lancet Psychiatry, 4(11), 868-875. doi:10.1016/s2215-0366(17)30394-2 Schiller, C. E., Meltzer-Brody, S., & Rubinow, D. R. (2015). The role of reproductive hormones in postpartum depression. CNS spectrums, 20(1), 48-59. doi:10.1017/S1092852914000480 Sciberras, E., Mulraney, M., Silva, D., & Coghill, D. (2017). Prenatal Risk Factors and the Etiology of ADHD-Review of Existing Evidence. Curr Psychiatry Rep, 19(1), 1. doi:10.1007/s11920-017-0753-2 Sheffield, P. E., Speranza, R., Chiu, Y. M., Hsu, H. L., Curtin, P. C., Renzetti, S., . . . Wright, R. J. (2018). Association between particulate air pollution exposure during pregnancy and postpartum maternal psychological functioning. PLoS One, 13(4), e0195267. doi:10.1371/journal.pone.0195267 Shih, P., Huang, C. C., Pan, S. C., Chiang, T. L., & Guo, Y. L. (2020). Hyperactivity disorder in children related to traffic-based air pollution during pregnancy. Environ Res, 188, 109588. doi:10.1016/j.envres.2020.109588 Shih, P., Wu, C.-D., Chiang, T.-l., Chen, P.-C., Su, T.-C., Cheng, T.-J., . . . Guo, Y. L. (2021). The association between postpartum depression and air pollution during pregnancy and postpartum period: a national population study in Taiwan. Environmental Research Letters, 16(8), 084021. doi:10.1088/1748-9326/ac1224 Shin, J., Park, J. Y., & Choi, J. (2018). Long-term exposure to ambient air pollutants and mental health status: A nationwide population-based cross-sectional study. PLoS One, 13(4), e0195607. doi:10.1371/journal.pone.0195607 Siddique, S., Banerjee, M., Ray, M. R., & Lahiri, T. (2011). Attention-deficit hyperactivity disorder in children chronically exposed to high level of vehicular pollution. European Journal of Pediatrics, 170(7), 923-929. doi:10.1007/s00431-010-1379-0 Silverman, M. E., Reichenberg, A., Savitz, D. A., Cnattingius, S., Lichtenstein, P., Hultman, C. M., . . . Sandin, S. (2017). The risk factors for postpartum depression: A population-based study. Depression and anxiety, 34(2), 178-187. doi:10.1002/da.22597 Skrundz, M., Bolten, M., Nast, I., Hellhammer, D. H., & Meinlschmidt, G. (2011). Plasma oxytocin concentration during pregnancy is associated with development of postpartum depression. Neuropsychopharmacology, 36(9), 1886-1893. doi:10.1038/npp.2011.74 Slomian, J., Honvo, G., Emonts, P., Reginster, J.-Y., & Bruyère, O. (2019). Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes. Women's health (London, England), 15, 1745506519844044-1745506519844044. doi:10.1177/1745506519844044 Soares-Cunha, C., Coimbra, B., Borges, S., Domingues, A. V., Silva, D., Sousa, N., & Rodrigues, A. J. (2018). Mild Prenatal Stress Causes Emotional and Brain Structural Modifications in Rats of Both Sexes. Front Behav Neurosci, 12, 129. doi:10.3389/fnbeh.2018.00129 Soma-Pillay, P., Nelson-Piercy, C., Tolppanen, H., & Mebazaa, A. (2016). Physiological changes in pregnancy. Cardiovascular journal of Africa, 27(2), 89-94. doi:10.5830/CVJA-2016-021 Teng, H.-W., Hsu, C.-S., Shih, S.-M., Lu, M.-L., Pan, J.-J., & Shen, W. W. (2005). Screening postpartum depression with the Taiwanese version of the Edinburgh Postnatal Depression Scale. Comprehensive Psychiatry, 46(4), 261-265. doi:https://doi.org/10.1016/j.comppsych.2004.10.003 Thomas, R., Sanders, S., Doust, J., Beller, E., & Glasziou, P. (2015). Prevalence of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Pediatrics, 135(4), e994-1001. doi:10.1542/peds.2014-3482 Varshavsky, J., Smith, A., Wang, A., Hom, E., Izano, M., Huang, H., . . . Woodruff, T. J. (2020). Heightened susceptibility: A review of how pregnancy and chemical exposures influence maternal health. Reproductive Toxicology, 92, 14-56. doi:https://doi.org/10.1016/j.reprotox.2019.04.004 Vert, C., Sánchez-Benavides, G., Martínez, D., Gotsens, X., Gramunt, N., Cirach, M., . . . Gascon, M. (2017). Effect of long-term exposure to air pollution on anxiety and depression in adults: A cross-sectional study. Int J Hyg Environ Health, 220(6), 1074-1080. doi:10.1016/j.ijheh.2017.06.009 Visser, S. N., Danielson, M. L., Bitsko, R. H., Holbrook, J. R., Kogan, M. D., Ghandour, R. M., . . . Blumberg, S. J. (2014). Trends in the Parent-report of Health Care Provider Diagnosed and Medicated ADHD: United States, 2003—2011. Journal of the American Academy of Child and Adolescent Psychiatry, 53(1), 34-46.e32. doi:10.1016/j.jaac.2013.09.001 Vrachnis, N., Malamas, F. M., Sifakis, S., Deligeoroglou, E., & Iliodromiti, Z. (2011). The oxytocin-oxytocin receptor system and its antagonists as tocolytic agents. International journal of endocrinology, 2011, 350546-350546. doi:10.1155/2011/350546 Wang, L. J., Lee, S. Y., Yuan, S. S., Yang, C. J., Yang, K. C., Huang, T. S., . . . Shyu, Y. C. (2017). Prevalence rates of youths diagnosed with and medicated for ADHD in a nationwide survey in Taiwan from 2000 to 2011. Epidemiology and Psychiatric Sciences, 26(6), 624-634. doi:10.1017/S2045796016000500 Watkins, S., Meltzer-Brody, S., Zolnoun, D., & Stuebe, A. (2011). Early breastfeeding experiences and postpartum depression. Obstet Gynecol, 118(2 Pt 1), 214-221. doi:10.1097/AOG.0b013e3182260a2d Wei, C. F., Chen, M. H., Lin, C. C., Guo, Y. L., Lin, S. J., Liao, H. F., . . . Chen, P. C. (2019). Association between maternal shift work and infant neurodevelopmental outcomes: results from the Taiwan Birth Cohort Study with propensity-score-matching analysis. Int J Epidemiol. doi:10.1093/ije/dyz045 Willcutt, E. G. (2012). The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. Neurotherapeutics, 9(3), 490-499. doi:10.1007/s13311-012-0135-8 Wong, P.-Y., Hsu, C.-Y., Wu, J.-Y., Teo, T.-A., Huang, J.-W., Guo, H.-R., . . . Spengler, J. D. (2021). Incorporating land-use regression into machine learning algorithms in estimating the spatial-temporal variation of carbon monoxide in Taiwan. Environmental Modelling & Software, 139, 104996. doi:https://doi.org/10.1016/j.envsoft.2021.104996 World Health Organization Regional Office for Europe. (2006). Air quality guidelines: global update 2005: particulate matter, ozone, nitrogen dioxide, and sulfur dioxide. Copenhagen: World Health Organization Regional Office for Europe. Wu, C.-D., Zeng, Y.-T., & Lung, S.-C. C. (2018). A hybrid kriging/land-use regression model to assess PM2.5 spatial-temporal variability. Science of The Total Environment, 645, 1456-1464. doi:https://doi.org/10.1016/j.scitotenv.2018.07.073 Xie, R. H., Yang, J., Liao, S., Xie, H., Walker, M., & Wen, S. W. (2010). Prenatal family support, postnatal family support and postpartum depression. Aust N Z J Obstet Gynaecol, 50(4), 340-345. doi:10.1111/j.1479-828X.2010.01185.x Xu, H., Ding, Y., Ma, Y., Xin, X., & Zhang, D. (2017). Cesarean section and risk of postpartum depression: A meta-analysis. Journal of Psychosomatic Research, 97, 118-126. doi:https://doi.org/10.1016/j.jpsychores.2017.04.016 Yolton, K., Khoury, J. C., Burkle, J., LeMasters, G., Cecil, K., & Ryan, P. (2019). lifetime exposure to traffic-related air pollution and symptoms of depression and anxiety at age 12 years. Environ Res, 173, 199-206. doi:10.1016/j.envres.2019.03.005 Yu, G., Chen, H., Wu, X., Matta, S. G., & Sharp, B. M. (2010). Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress. J Neurochem, 113(4), 919-929. doi:10.1111/j.1471-4159.2010.06654.x Zeng, Y., Lin, R., Liu, L., Liu, Y., & Li, Y. (2019). Ambient air pollution exposure and risk of depression: A systematic review and meta-analysis of observational studies. Psychiatry Res, 276, 69-78. doi:10.1016/j.psychres.2019.04.019 Zijlema, W. L., Wolf, K., Emeny, R., Ladwig, K. H., Peters, A., Kongsgård, H., . . . Rosmalen, J. G. (2016). The association of air pollution and depressed mood in 70,928 individuals from four European cohorts. Int J Hyg Environ Health, 219(2), 212-219. doi:10.1016/j.ijheh.2015.11.006 | - |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80958 | - |
| dc.description.abstract | 空氣污染物暴露及環境職業因素可能有神經毒性或影響心理健康，而懷孕者及胎兒更是相關危害暴露的易感族群。父母對孩童健康，常主訴有生長發育障礙，而其中注意力不足過動症是全球最常見的孩童神經行為疾患；產後憂鬱症是產後母親普遍且嚴重的心理健康問題，易引發個人及家庭的負面影響。雖然近年來流行病學研究顯示，懷孕期間空氣污染物暴露及母親環境因素皆會增加上述疾病的罹病風險，但相關實驗設計及結果尚未能有一致性結論，且亦欠缺本土性流行病學資料。本研究期望能利用本土性世代研究資料，評估母親於早期的環境職業因子與空氣污染暴露是否會增加孩童過動症或產後憂鬱症之風險，具體目標為： 1.評估妊娠階段空氣污染物暴露濃度高低，對於出生後孩童罹患過動症（Hyperactivity disorder）的影響。 2.比較懷孕期間持續工作的母親於高工作壓力的環境，對於此胎未來發生過動症（Hyperactivity disorder）的關聯。 3.探討懷孕時期空氣污染物對於產後憂鬱症（Postpartum depression）的潛在效應。 本研究使用台灣出生世代研究（Taiwan Birth Cohort Study），評估母親及孩童相關疾病與危險因子狀況，並針對2004年至2005年的台灣環保署空氣品質監測網（Air Quality Monitoring Network）的空氣污染物數據，使用地理資訊系統（Geographic Information System）的空間分析方法，進行個人懷孕不同時期的空污暴露狀況配對，以探討懷孕時期的環境職業差異對於孩童與母親後續的健康效應之關聯強度。 第一部分研究結果發現，在納入最終分析的16376對母嬰中，有374名（2.3%）兒童在8歲之前曾被診斷出過動症。過動症的發生與妊娠時氮氧化物（NOx）暴露顯著相關，但與直徑小於或等於10微米的顆粒物（PM10）或二氧化硫無關。進一步以二氧化氮（NO2）以及一氧化氮（NO）分析，則只有NO與過動性成顯著相關（aOR per 3.14 ppb=1.26，95% CI= 1.09-1.46）。第二部分研究結果，在10,559名於懷孕期間繼續工作的母親中，與沒有工作壓力者相比，若在懷孕期間從事“非常有壓力的工作”者的孩童有1.91倍的機率將於8歲前被診斷過動症（95% CI: 1.21-3.04)，而具有“相當壓力的工作”者的孩童則有1.53倍的風險（95% CI: 1.04- 2.25）。而第三部分研究結果我們發現，在21,205名婦女間有3,654名（17.2％）在產後6個月內發生了產後憂鬱症。產後憂鬱症發生與懷孕期間暴露於一氧化碳（CO）和二氧化氮（NO2）顯著相關，但與直徑≤2.5μm的顆粒物(PM2.5)無關。經過反向逐步選擇探討不同時期空氣污染物暴露情況，懷孕早期的NO2暴露仍與產後憂鬱症呈現顯著相關（aOR per 10.7 ppb=1.081，95% CI= 1.003-1.165）。 綜上，我們發現懷孕時期若暴露到較高濃度的特定空氣汙染物或高壓力的工作，確實會影響出生後孩童的神經行為疾患以及母親產後心理狀態。因此，確切的治病機轉及其長期健康效應值得持續研究並進一步釐清。 | zh_TW |
| dc.description.abstract | Air pollutant exposure and environmental and occupational factors have neurotoxicity or affect mental health. For pregnant women and fetuses, they are susceptible to related hazards. Growth and development disorders are common complaints for children’s parents. Among them, attention deficit hyperactivity disorder is the most common neurobehavioral disorder in children around the world. Postpartum depression is a common and serious mental health problem for mothers after delivery, and easily causing negative impacts on individuals and families. Though recent epidemiological studies indicated air pollutions and environmental exposures during pregnancy may increase risks of the diseases, literature shows controversies, and most of previous researches were done in other countries with lacking of data in Taiwan. By using Taiwanese cohort studies, we aim to determine whether perinatal environmental risk factors, like air pollutants and maternal environmental factors, increase risk of childhood hyperactivity disorder and postpartum depression. The specific goals of the study include: 1.Evaluate the risk of gestational exposure to air pollution on offspring hyperactivity disorders. 2.Compare the strength of the relationship between work-related job stress during pregnancy and the future occurrence of children hyperactivity disorder. 3.Explore the potential roles of maternal air pollutants during pregnancy in postpartum depression. The national database-Taiwan birth cohort study was used to assess mothers and children related diseases and risk factors. Based on the air pollutant data of the Environmental Protection Agency's Air Quality Monitoring Network from 2004 to 2005, the spatial analysis method of Geographic Information System was used to match the air pollution exposure condition of individuals in different periods of pregnancy. We then explored the correlation of environmental and occupational differences during pregnancy on the subsequent health effects of the child and the mother. In the first part of the study, a total of 16,376 mother–infant pairs were included and 374 (2.3%) of the children had received a diagnosis of hyperactivity before 8 years of age. The occurrence of hyperactivity was significantly related to prenatal nitrogen oxide (NOx), but not to particulate matter 10 micrometers or less in diameter (PM10) or sulfur dioxide. Further analysis to separate effects by nitrogen dioxide (NO2) and/or nitrogen monoxide (NO) showed that only NO was significantly related to hyperactivity (aOR per 3.14 ppb=1.26，95% CI= 1.09-1.46). Secondly, 10,559 mothers who continued working during pregnancy were included in the final analysis. Compared with mothers without job stress, the adjusted odds ratio of child hyperactivity was 1.91 (95% CI: 1.21-3.04) for mothers with “very stressful” jobs during pregnancy and 1.53 (95% CI: 1.04- 2.25) for mothers with “rather stressful” jobs. Lastly, 3,654 (17.2%) developed Postpartum depression within 6 months postpartum among 21,205 participants. The occurrence of postpartum depression was significantly related to exposure to ambient concentrations of carbon monoxide (CO) and NO2 during pregnancy, but not to particulate matter ≤2.5µm in diameter (PM2.5). While relationship between postpartum depression and exposure during different periods was investigated using backward stepwise selection, NO2 exposure in the first trimester remained significantly related to postpartum depression (aOR per 10.7 ppb=1.081，95% CI= 1.003-1.165). In conclusion, we have found that exposure to higher levels of specific air pollutants or higher job stress during pregnancy do affect the children neurobehavioral outcome and the mental health status of the mothers after childbirth. Future investigation is indicated to elucidate the possible underlying mechanisms and long-term health effects. | en |
| dc.description.provenance | Made available in DSpace on 2022-11-24T03:23:39Z (GMT). No. of bitstreams: 1 U0001-0909202109524600.pdf: 5093860 bytes, checksum: ad1da031277f64c1e5a3509edcff277c (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 論文口試委員審定書 i 謝辭 vi 摘要 vii Abstract ix Contents xii List of Figures xv List of Tables xvi Glossary xvii Chapter 1 Introduction 1 Maternal health during pregnancy 1 Attention-deficit hyperactivity disorder 1 Postpartum depression 2 Air pollution and attention-deficit hyperactivity disorder 3 Stress and attention-deficit hyperactivity disorder 4 Air pollution and postpartum depression 5 Objectives 7 Chapter 2 Material and Methods 8 2.1 Air pollution during pregnancy and offspring hyperactivity in Taiwan 8 2.1.1 Cohort Description, study population and sampling 8 2.1.2 Questionnaire and neurodevelopmental outcome 9 2.1.3 Exposure assessment 9 2.1.4 Covariates 11 2.1.5 Statistical analysis 11 2.2 Maternal job stress during pregnancy and offspring hyperactivity in Taiwan 12 2.2.1 Study population and sampling 12 2.2.2 Exposure, covariates, and neurodevelopmental outcome 12 2.2.3 Statistical analysis 14 2.3 Air pollution during pregnancy and postpartum depression in Taiwan 14 2.3.1 Study population and sampling 14 2.3.2 Questionnaire and dependent outcome 15 2.3.3 Exposure assessment 16 2.3.4 Statistical analysis 17 Chapter 3 Results 19 3.1 Air pollution during pregnancy and offspring hyperactivity in Taiwan 19 3.1.1 Characteristics of the enrolled cohort 19 3.1.2 Distribution of air pollutants 20 3.1.3 Risk of hyperactivity 20 3.2 Maternal job stress during pregnancy and offspring hyperactivity in Taiwan 20 3.2.1 Characteristics of the enrolled cohort 20 3.2.2 Distribution of job stress 21 3.2.3 Risk of hyperactivity 22 3.3 Air pollution during pregnancy and postpartum depression in Taiwan 22 3.3.1 Characteristics of the enrolled cohort 22 3.3.2 Distribution of air pollutants 23 3.3.3 Risk of postpartum depression 23 Chapter 4 Discussion 25 4.1 Air pollution during pregnancy and offspring hyperactivity in Taiwan 25 4.1.1 Major findings 25 4.1.2 Consistency with previous knowledge 25 4.1.3 Possible mechanism 27 4.2 Maternal job stress during pregnancy and offspring hyperactivity in Taiwan 28 4.2.1 Major findings 28 4.2.2 Consistency with previous knowledge 29 4.2.3 Possible mechanism 31 4.3 Air pollution during pregnancy and postpartum depression in Taiwan 32 4.3.1 Major findings 32 4.3.2 Consistency with previous knowledge 33 4.3.3 Possible mechanism 37 4.4 Limitations 38 4.5 Strengths 40 Chapter 5 Conclusion 43 Reference 44 Publication List 88 Appendix 90 | - |
| dc.language.iso | en | - |
| dc.subject | Hyperactivity disorder | zh_TW |
| dc.subject | Job stress | zh_TW |
| dc.subject | Pregnancy | zh_TW |
| dc.subject | Air pollution | zh_TW |
| dc.subject | Postpartum depression | zh_TW |
| dc.subject | Cohort study | zh_TW |
| dc.subject | 過動症 | en |
| dc.subject | 產後憂鬱症 | en |
| dc.subject | 空氣污染 | en |
| dc.subject | 懷孕時期 | en |
| dc.subject | 工作壓力 | en |
| dc.subject | 世代追蹤研究 | en |
| dc.title | 懷孕期間環境職業因素對胎兒及母親健康之影響 | zh_TW |
| dc.title | Maternal and Fetal Health Effects of Prenatal Environmental and Occupational Factors | en |
| dc.type | Thesis | - |
| dc.date.schoolyear | 109-2 | - |
| dc.description.degree | 博士 | - |
| dc.contributor.coadvisor | 陳保中 | zh_TW |
| dc.contributor.coadvisor | Pau-Chung Chen | en |
| dc.contributor.oralexamcommittee | 鄭尊仁;江東亮;李中一;陳怡樺;蘇大成;吳治達 | zh_TW |
| dc.contributor.oralexamcommittee | Tsun-Jen Cheng;Tung-liang Chiang;Chung-Yi Li;Yi-Hua Chen;Ta-Chen Su;Chih-Da Wu | en |
| dc.subject.keyword | Hyperactivity disorder,Postpartum depression,Air pollution,Pregnancy,Job stress,Cohort study, | zh_TW |
| dc.subject.keyword | 過動症,產後憂鬱症,空氣污染,懷孕時期,工作壓力,世代追蹤研究, | en |
| dc.relation.page | 91 | - |
| dc.identifier.doi | 10.6342/NTU202103077 | - |
| dc.rights.note | 未授權 | - |
| dc.date.accepted | 2021-09-11 | - |
| dc.contributor.author-college | 公共衛生學院 | - |
| dc.contributor.author-dept | 環境與職業健康科學研究所 | - |
| dc.date.embargo-lift | N/A | - |
| 顯示於系所單位： | 環境與職業健康科學研究所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-109-2.pdf 未授權公開取用 | 4.97 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。