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  1. NTU Theses and Dissertations Repository
  2. 醫學院
  3. 國際三校農業生技與健康醫療碩士學位學程
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80709
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dc.contributor.advisor詹長權(Chang-Chuan Chan)
dc.contributor.authorNien-Chen Linen
dc.contributor.author林念蓁zh_TW
dc.date.accessioned2022-11-24T03:13:39Z-
dc.date.available2021-11-03
dc.date.available2022-11-24T03:13:39Z-
dc.date.copyright2021-11-03
dc.date.issued2021
dc.date.submitted2021-10-18
dc.identifier.citationAllen, J., Balfour, R., Bell, R., Marmot, M. (2014). Social determinants of mental health. International review of psychiatry, 26(4), 392-407. Berger, M., Gray, J. A., Roth, B. L. (2009). The expanded biology of serotonin. Annual review of medicine, 60, 355-366. Bhugra, D., Till, A., Sartorius, N. (2013). What is mental health? In: SAGE Publications Sage UK: London, England. Charlson, F. J., Baxter, A. J., Dua, T., Degenhardt, L., Whiteford, H. A., Vos, T. (2015). Excess mortality from mental, neurological and substance use disorders in the Global Burden of Disease Study 2010. Epidemiology and psychiatric sciences, 24(2), 121-140. Conference, I. H. (2002). Constitution of the World Health Organization. 1946. Bulletin of the World Health Organization, 80(12), 983. Gale, C. R., Robinson, S. M., Godfrey, K. M., Law, C. M., Schlotz, W., O’Callaghan, F. (2008). Oily fish intake during pregnancy–association with lower hyperactivity but not with higher full‐scale IQ in offspring. Journal of Child Psychology and Psychiatry, 49(10), 1061-1068. Gould, N. (2016). Mental health social work in context: Routledge. Hassanzadeh, A., Heidari, Z., Feizi, A., Hassanzadeh Keshteli, A., Roohafza, H., Afshar, H., Adibi, P. (2017). Association of stressful life events with psychological problems: a large-scale community-based study using grouped outcomes latent factor regression with latent predictors. Computational and mathematical methods in medicine, 2017. Hornykiewicz, O. (1966). Dopamine (3-hydroxytyramine) and brain function. Pharmacological reviews, 18(2), 925-964. Kadawathagedara, M. (2018). Maternal diet during pregnancy and early growth: Focus on diet duality and food chemicals exposure. Université Paris-Saclay, Kadawathagedara, M., TRAORE, T., Carles, S., Charles, M.-A., Heude, B., Hulin, M., Sirot, V., de Lauzon-Guillain, B., Crépet, A., Botton, J. (2016). Maternal Exposure to Mixtures of Food Chemicals in Relation with Offspring Birthweight and Postnatal Growth. Paper presented at the ISEE Conference Abstracts. Liese, B. H., Gribble, R. S., Wickremsinhe, M. N. (2019). International funding for mental health: a review of the last decade. International health, 11(5), 361-369. Litin, S. C., Nanda, S. (2009). Mayo clinic family health book: Time Incorporated Home Entertainment. Metrics, I. f. H., Evaluation. (2017). Global Burden of Disease Collaborative Network. Global Burden of Disease Study 2016 (GBD 2016) Results. In: Institute for Health Metrics and Evaluation Seattle. Organization, W. H. (2018). Suicide rate estimates, age-standardised Estimates by country. In. Organization, W. H. (2019). The WHO special initiative for mental health (‎‎‎ 2019-2023)‎‎‎‎: universal health coverage for mental health. Retrieved from Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T., Keck Jr, P. E., Leverich, G. S. (2018). Multigenerational transmission of liability to psychiatric illness in offspring of parents with bipolar disorder. Bipolar disorders, 20(5), 432-440. Rehm, J., Shield, K. D. (2019). Global burden of disease and the impact of mental and addictive disorders. Current psychiatry reports, 21(2), 1-7. Richardson, A. J. (2003). The importance of omega-3 fatty acids for behaviour, cognition and mood. Scandinavian Journal of Nutrition, 47(2), 92-98. Sacker, A. (2013). Mental health and social relationships. Evidence Briefing of the Economic and Social Research Council. Schiffer, B., Leygraf, N., Müller, B. W., Scherbaum, N., Forsting, M., Wiltfang, J., Gizewski, E. R., Hodgins, S. (2013). Structural brain alterations associated with schizophrenia preceded by conduct disorder: a common and distinct subtype of schizophrenia? Schizophrenia bulletin, 39(5), 1115-1128. Urbanoski, K., Inglis, D. (2019). Performance measurement in mental health and addictions systems: A scoping review. Journal of Studies on Alcohol and Drugs, Supplement(s18), 114-130. Walker, E. R., McGee, R. E., Druss, B. G. (2015). Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA psychiatry, 72(4), 334-341. 全國自殺防治中心. (2020). 全國自殺死亡資料統計. 心理及口腔健康司 Retrieved from https://dep.mohw.gov.tw/domhaoh/cp-4904-8883-107.html
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80709-
dc.description.abstract食品中污染物質與毒素對於孕婦的健康危害在過去許多研究中不斷被探討,然而,以懷孕期間暴露於食品污染物為主軸,探討其影響新生兒早期心智發展的統整性研究,較少被納入營養流行病學中。 這份研究旨在透過量化工具,探究食品污染物與毒素之產前暴露量與孩童3至8歲間心理健康發展的關聯性。本研究中的1289位母嬰配對樣本資料,是來自法國國家衛生研究院與2家分別位於普瓦捷與南錫之大學附屬醫院合作,所做的婦幼出生世代研究。研究主要分為兩部分,第一部分利用系列研究中,已透過社交行為表現量表評估、群體化軌跡模式計算之新生兒早期心理健康發展傾向,來清理資料並進行分組分析,包含注意力不足過動症、焦慮與憂鬱症狀、行為規範障礙症、利社會行為,以及上述症狀之綜合評估等應變項。第二部分則採用符合法國民情的飲食頻率問卷,所量化取得之454種食品污染物與毒素於孕期間被攝取的含量,作為自變項。進而透過機器學習演算法,探勘各污染物與毒素和負向心理健康發展之關聯強度,並剔除低重要性之自變項,以較保守之估計進行多元邏輯斯回歸分析。 本研究結果反映母體孕期間飲食習慣可能影響孩童心理健康發展,可作為未來學界進行實驗研究之數據參考,也為相關介入性研究的方法和指南奠下基礎。zh_TW
dc.description.provenanceMade available in DSpace on 2022-11-24T03:13:39Z (GMT). No. of bitstreams: 1
U0001-1810202106553800.pdf: 2632289 bytes, checksum: 977015c835ce9c6ec7ec95f7babeb32a (MD5)
Previous issue date: 2021
en
dc.description.tableofcontents致謝....................ii Acknowledgements........iii 中文摘要..................v Abstract................vi Comprehensive Report......1 A.Introduction......1 B.Materials and Methods......5 C.Results......8 D.Discussion......16 E.Limitations......16 F.Conclusion......17 References................18
dc.language.isoen
dc.subject邏輯斯回歸zh_TW
dc.subject食品污染物與毒素zh_TW
dc.subject母嬰配對zh_TW
dc.subject兒童心理衛生zh_TW
dc.subject機器學習zh_TW
dc.subjectFood contaminantsen
dc.subjectLogistic regressionen
dc.subjectMachine learningen
dc.subjectEarly mental healthen
dc.subjectMother-child cohorten
dc.title孕期間母體飲食暴露對其胎兒早期心理衛生發展之影響:世代分析研究zh_TW
dc.titleExposure to Food Contaminants and the Associated Early Childhood Mental Health in France: The EDEN Cohorten
dc.date.schoolyear109-2
dc.description.degree碩士
dc.contributor.oralexamcommittee李財坤(Hsin-Tsai Liu),林先和(Chih-Yang Tseng)
dc.subject.keyword食品污染物與毒素,母嬰配對,兒童心理衛生,機器學習,邏輯斯回歸,zh_TW
dc.subject.keywordFood contaminants,Mother-child cohort,Early mental health,Machine learning,Logistic regression,en
dc.relation.page20
dc.identifier.doi10.6342/NTU202103805
dc.rights.note同意授權(限校園內公開)
dc.date.accepted2021-10-19
dc.contributor.author-college醫學院zh_TW
dc.contributor.author-dept國際三校農業生技與健康醫療碩士學位學程zh_TW
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