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  1. NTU Theses and Dissertations Repository
  2. 公共衛生學院
  3. 環境與職業健康科學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80531
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dc.contributor.advisor陳志傑(Chih-Chieh Chen)
dc.contributor.authorChun-Ting Liuen
dc.contributor.author劉俊廷zh_TW
dc.date.accessioned2022-11-24T03:08:42Z-
dc.date.available2021-11-05
dc.date.available2022-11-24T03:08:42Z-
dc.date.copyright2021-11-05
dc.date.issued2021
dc.date.submitted2021-10-26
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Effect of added dead‐space on pulmonary ventilation during sub‐maximal, steady‐state exercise. Quarterly Journal of Experimental Physiology and Cognate Medical Sciences: Translation and Integration 58:305-313. Lee, W. (2013). Development of a design methodology of pilot oxygen mask using 3d facial scan data: Pohang University of Science and Technology, Korea. Lin, Y.-C. and C.-P. Chen. (2017). Characterization of small-to-medium head-and-face dimensions for developing respirator fit test panels and evaluating fit of filtering facepiece respirators with different faceseal design. PLOS ONE 12:e0188638. Makowski, K. and M. Okrasa. (2019). Application of 3d scanning and 3d printing for designing and fabricating customized half-mask facepieces: A pilot study. Work 63:125-135. Messina, Z. and H. Patrick. 2021. Partial pressure of carbon dioxide, in Statpearls. Treasure Island (FL): StatPearls Publishing Copyright © 2021, StatPearls Publishing LLC. Murias, G., L. Blanch, U. Lucangelo. (2014). The physiology of ventilation. Respiratory Care 59:1795-1807. Ngo, T. D., A. Kashani, G. Imbalzano, K. T. Q. Nguyen, D. Hui. (2018). Additive manufacturing (3d printing): A review of materials, methods, applications and challenges. Composites Part B: Engineering 143:172-196. NIOSH. (1995). 42 cfr part 84 - approval of respiratory protective devices. Oestenstad, R. K., H. K. Dillion, L. L. Perkins. (1990). Distribution of faceseal leak sites on a half-mask respirator and their association with facial dimensions. American Industrial Hygiene Association Journal 51:285-290. Plowman, S. A. and D. L. Smith. (2017). Exercise physiology for health, fitness, and performance: Wolters Kluwer. Provenzano, D., Y. J. Rao, K. Mitic, S. N. Obaid, D. Pierce, J. Huckenpahler, J. Berger, S. Goyal, M. H. Loew. (2020). Rapid prototyping of reusable 3d-printed n95 equivalent respirators at the george washington university. Sackner, J. D., A. J. Nixon, B. Davis, N. Atkins, M. A. Sackner. (1980). Effects of breathing through external dead space on ventilation at rest and during exercise. Ii. American Review of Respiratory Disease 122:933-940. Sietsema, K. E., D. Y. Sue, W. W. Stringer, S. Ward. (2020). Wasserman whipp's principles of exercise testing and interpretation: Wolters Kluwer. Spies, A., K. S. Wilson, R. Ferrie. (2011). Respirator fit of a medium mask on a group of south africans: A cross-sectional study. Environmental health 10:17. Swennen, G. R., L. Pottel, P. E. Haers. (2020). Custom-made 3d-printed face masks in case of pandemic crisis situations with a lack of commercially available ffp2/3 masks. International Journal of Oral and Maxillofacial Surgery. Wang, X., M. Jiang, Z. Zhou, J. Gou, D. Hui. (2017). 3d printing of polymer matrix composites: A review and prospective. Composites Part B: Engineering 110:442-458. Ward, S. A. and B. J. Whipp. (1980). Ventilatory control during exercise with increased external dead space. Journal of Applied Physiology 48:225-231. West, J. B. and A. M. Luks. (2021). West's respiratory physiology the essentials Wolters Kluwer. Whipp, B. J. (2014). When is 863 actually 863? Whitesell, R., C. Asiddao, D. Gollman, J. Jablonski. (1981). Relationship between arterial and peak expired carbon dioxide pressure during anesthesia and factors influencing the difference. Anesth Analg 60:508-512. Xu, M., Z. Lei, J. Yang. (2015). Estimating the dead space volume between a headform and n95 filtering facepiece respirator using microsoft kinect. Journal of Occupational and Environmental Hygiene 12:538-546. Zhuang, Z., S. Benson, D. Viscusi. (2010). Digital 3-d headforms with facial features representative of the current us workforce. Ergonomics 53:661-671. Zhuang, Z. and B. Bradtmiller. (2005). Head-and-face anthropometric survey of u.S. Respirator users. Journal of Occupational and Environmental Hygiene 2:567-576. Zhuang, Z., B. Bradtmiller, R. E. Shaffer. (2007). New respirator fit test panels representing the current us civilian work force. Journal of occupational and environmental hygiene 4:647-659. Zhuang, Z., C. C. Coffey, R. B. Ann. (2005). The effect of subject characteristics and respirator features on respirator fit. Journal of Occupational and Environmental Hygiene 2:641-649. 吳念國. (2016). 以臉的大小及深度尺碼分群設計半面型呼吸面罩, in 工業工程與工程管理學系: 國立清華大學. 陳宏洋. (2020). 客製化半面式呼吸防護具之效能評估, in 環境與職業健康科學研究所: 國立臺灣大學. 游承恩. (2016). 改進顏面硬骨部位貼合的呼吸面罩設計方法, in 工業工程與工程管理學系: 國立清華大學. 楊宜學. (2002). 勞工3d頭型資料庫之建立與頭部防護具之設計應用, in 工業工程與工程管理學系: 國立清華大學. 廖秀珍. (2005). 應用3d顱顏資料庫設計呼吸面罩, in 工業工程與工程管理學系: 國立清華大學. 盧靖安. (2019). 新世代呼吸防護具的研發, in 職業醫學與工業衛生研究所: 國立臺灣大學.
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80531-
dc.description.abstract"客製化呼吸防護具可以提供比制式化面罩更好的密合度。客製化面罩的設計流程可分為3D掃描頭模、建立3D面罩模型、3D列印出面罩此三個部分。此外,客製化面罩還可以控制面罩的死腔體積。本研究之目的為建立一個設計客製化面罩的標準流程,同時在設計過程中將面罩死腔最小化,並且瞭解佩戴最小死腔面罩的可接受程度,以及探討面罩死腔最小化對於呼吸生理反應造成的影響。 本研究招募十一名受試者,使用EinScan 3D掃描儀(Shining 3D, Hangzhou, China)取得受試者頭部3D資料,使用鼻樑長度、鼻尖到嘴唇長度、下臉長度、鼻寬度與嘴唇寬度,共五個臉部特徵長度來設計客製化面罩。同時使用1.1、1.2、1.3三個嘴唇寬度的倍數來決定三種不同的左右吸氣閥距離,並結合三種不同呼氣閥底部連接方式(與呼氣閥同高、低5 mm、低10 mm),來調整面罩死腔體積大小,設計出九款不同大小的最小死腔客製化面罩,接著以3D列印機(Apollo 2.0, Prolink)製作出面罩。將面罩給受試者佩戴後,以問卷調查佩戴體驗。呼吸生理反應的部分,由一名受試者佩戴死腔分別為38, 132, 330 mL的三款面罩,進行運動心肺功能測試(CPX testing),在運動負荷0到100 W的狀況下,測量佩戴不同面罩運動時,潮氣容積、呼吸頻率、每分鐘通氣量、心率、吸入二氧化碳濃度與潮氣末二氧化碳分壓的變化。 研究結果顯示可以最小化面罩死腔,又不會使呼吸阻抗超過NIOSH標準的最佳閥直徑為25 mm。本研究設計最小死腔客製化面罩,體積約為30 – 50 mL,與市售面罩相比,可降低70 %以上的面罩死腔。根據問卷調查結果,受試者大多都認為最小死腔客製化面罩的佩戴體驗可以接受,且得分最高的面罩之佩戴體驗已經接近市售面罩。運動心肺功能測試方面,結果顯示與市售半面罩相比,佩戴最小死腔面罩,可以降低吸入二氧化碳的濃度(FICO2)達1 %以上,且在相同的運動負荷下,潮氣容積可以降低至少20 %。在運動負荷為100 W時,38與132 mL面罩的每分鐘通氣量比330 mL面罩低約20 %。 總結來說,使用鼻樑長度、鼻尖到嘴唇長度、下臉長度、鼻寬度與嘴唇寬度足以建立一個標準化的最小死腔客製化面罩設計流程。本研究設計之面罩可降低70 %以上的死腔,且大多數的使用者都認為佩戴體驗可以接受。在將面罩死腔最小化之後,能降低面罩內二氧化碳濃度、潮氣容積以及每分鐘通氣量,減輕呼吸的負擔。"zh_TW
dc.description.provenanceMade available in DSpace on 2022-11-24T03:08:42Z (GMT). No. of bitstreams: 1
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Previous issue date: 2021
en
dc.description.tableofcontents口試委員會審定書 2 致謝 4 摘要 5 Abstract 7 目錄 10 表目錄 13 圖目錄 14 第一章、研究背景與目的 15 1.1 研究背景 15 1.2 研究目的 16 第二章、文獻回顧 17 2.1 設計呼吸防護具面罩需考量的臉部特徵 17 2.2 3D掃描技術 17 2.3 3D列印技術 18 2.4 現行3D掃描與3D列印製作呼吸防護具方法 19 2.5 市售面罩與客製化面罩的密合程度 20 2.6 面罩尺寸分類 21 2.7 3D人體計測於呼吸防護具設計的應用 22 2.8 面罩死腔的影響 23 2.9 文獻回顧小結 24 第三章、研究材料與方法 26 3.1 研究架構 26 3.2 受試者頭模資料 26 3.3 最小死腔客製化面罩設計 27 3.3.1 頭模擺正 27 3.3.2 臉部特徵點選取 27 3.3.3 臉部特徵長度量測 28 3.3.4 臉部特徵長度投影長度計算 29 3.3.5 面罩連接點計算 30 3.3.6 貝茲曲線調整 31 3.3.7 呼氣閥與吸氣閥直徑 32 3.3.8 面罩主體結構:左右吸氣閥距離 33 3.3.9 面罩主體結構:呼氣閥底部連接方式 34 3.3.10 九種不同尺寸面罩之死腔體積計算 35 3.4 不同尺寸面罩佩戴體驗調查 35 3.4.1 3D列印九種不同尺寸的面罩 35 3.4.2 佩戴體驗問卷調查 35 3.5 最小化面罩死腔體積之生理影響實驗 36 3.5.1 運動心肺功能測試 (CPX testing) 36 3.5.2 模式計算面罩死腔體積、潮氣容積與動脈血二氧化碳分壓的關係 36 第四章、結果與討論 39 4.1 臉部特徵長度測量結果 39 4.2 呼氣閥與吸氣閥開口直徑 39 4.3 面罩死腔體積大小 40 4.4 最小死腔之客製化面罩接受度問卷調查結果 40 4.5 不同死腔體積面罩之運動心肺功能測試結果 41 4.5.1 吸入二氧化碳濃度 41 4.5.2 潮氣容積、呼吸頻率、每分鐘通氣量與心率 42 4.5.3 潮氣末二氧化碳分壓 44 4.5.4 面罩死腔與生理反應:與其他研究之比較 45 4.5.5 運動心肺功能測試結果與模式計算結果之比較 46 4.6 研究限制 47 第五章、結論與建議 48 第六章、參考文獻 49 附錄一、面罩舒適度評估問卷 81 附錄二、面罩機能性評估問卷 82
dc.language.isozh-TW
dc.subject口罩zh_TW
dc.subject客製化zh_TW
dc.subject呼吸防護zh_TW
dc.subject3D掃描zh_TW
dc.subject3D列印zh_TW
dc.subject死腔zh_TW
dc.subject面罩zh_TW
dc.subject3D printingen
dc.subjectmasken
dc.subjectdead spaceen
dc.subjectcustomized respiratorsen
dc.subject3D scanningen
dc.title最小死腔之客製化呼吸防護具研發zh_TW
dc.titleDevelopment of Customized Respirators with Minimal Dead Spaceen
dc.date.schoolyear109-2
dc.description.degree碩士
dc.contributor.oralexamcommittee吳章甫(Hsin-Tsai Liu),鄭尊仁(Chih-Yang Tseng),黃耀輝,黃盛修
dc.subject.keyword客製化,呼吸防護,3D掃描,3D列印,死腔,面罩,口罩,zh_TW
dc.subject.keywordcustomized respirators,3D scanning,3D printing,dead space,mask,en
dc.relation.page82
dc.identifier.doi10.6342/NTU202104232
dc.rights.note同意授權(限校園內公開)
dc.date.accepted2021-10-26
dc.contributor.author-college公共衛生學院zh_TW
dc.contributor.author-dept環境與職業健康科學研究所zh_TW
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