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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 林璧鳳 | |
dc.contributor.author | Pei-Ting Shen | en |
dc.contributor.author | 沈蓓婷 | zh_TW |
dc.date.accessioned | 2021-07-11T14:43:40Z | - |
dc.date.available | 2021-10-14 | |
dc.date.copyright | 2016-10-14 | |
dc.date.issued | 2016 | |
dc.date.submitted | 2016-08-10 | |
dc.identifier.citation | 史維廉、黃伯超 (1987),我國足月產婦的母乳營養成分之研究,中國文化大學家政學研究所碩士論文
行政院衛福部 (2002),食品化學檢驗方法之確效規範 行政院衛福部 (2008),食品中維生素D之檢驗方法,食字第0971800323號公告訂定 行政院衛福部 (2011),國人膳食營養素參考攝取量修訂第七版 許喬琳、吳碧娟、陳怡吟、杜明勳 (2005),哺乳的營養需求及對母親的影響,家庭醫學與基層醫療 陳冠如、林璧鳳、林以勤、潘文涵 (2008),台灣十年來國人葉酸營養狀況的變遷: 由 NASHIT 1993-1996 到 2005-2008 賴智豪、高美丁 (2011),台灣地區女性鐵攝取與鐵營養狀況及其影響因子之研究,靜宜大學食品營養學系碩士論文 Abe, E., Miyaura, C., Sakagami, H., Takeda, M., Konno, K., Yamazaki, T., et al. (1981). Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A 78(8): 4990-4994. Adorini, L., Penna, G., Giarratana, N., Roncari, A., Amuchastegui, S., Daniel, K. C., et al. (2004). Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligands. J Steroid Biochem Mol Biol 89-90(1-5): 437-441. Agmon-Levin, N., Theodor, E., Segal, R. M. and Shoenfeld, Y. (2013). Vitamin D in systemic and organ-specific autoimmune diseases. Clin Rev Allergy Immunol 45(2): 256-266. Alm, B., Aberg, N., Erdes, L., Mollborg, P., Pettersson, R., Norvenius, S. G., et al. (2009). Early introduction of fish decreases the risk of eczema in infants. Arch Dis Child 94(1): 11-15. Amestejani, M., Salehi, B. S., Vasigh, M., Sobhkhiz, A., Karami, M., Alinia, H., et al. (2012). Vitamin D supplementation in the treatment of atopic dermatitis: a clinical trial study. J Drugs Dermatol 11(3): 327-330. Andreas, N. J., Kampmann, B. and Mehring Le-Doare, K. (2015). Human breast milk: A review on its composition and bioactivity. Early Hum Dev 91(11): 629-635. Aranow, C. (2011). Vitamin D and the immune system. J Investig Med 59(6): 881-886. Asher, M. I., Montefort, S., Bjorksten, B., Lai, C. K., Strachan, D. P., Weiland, S. K., et al. (2006). Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 368(9537): 733-743. Baek, J. H., Shin, Y. H., Chung, I. H., Kim, H. J., Yoo, E. G., Yoon, J. W., et al. (2014). The link between serum vitamin D level, sensitization to food allergens, and the severity of atopic dermatitis in infancy. J Pediatr 165(4): 849-854 e841. Ballard, O. and Morrow, A. L. (2013). Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am 60(1): 49-74. Benson, M. J., Pino-Lagos, K., Rosemblatt, M. and Noelle, R. J. (2007). All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med 204(8): 1765-1774. Bieber, T. (2008). Atopic dermatitis. N Engl J Med 358(14): 1483-1494. Bohme, M., Wickman, M., Lennart Nordvall, S., Svartengren, M. and Wahlgren, C. F. (2003). Family history and risk of atopic dermatitis in children up to 4 years. Clin Exp Allergy 33(9): 1226-1231. Boonstra, A., Barrat, F. J., Crain, C., Heath, V. L., Savelkoul, H. F. and O'Garra, A. (2001). 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol 167(9): 4974-4980. Bottcher, M. F., Jenmalm, M. C., Garofalo, R. P. and Bjorksten, B. (2000). Cytokines in breast milk from allergic and nonallergic mothers. Pediatr Res 47(1): 157-162. Brooker, B. E. (1980). The epithelial cells and cell fragments in human milk. Cell Tissue Res 210(2): 321-332. Brown, C. C. and Noelle, R. J. (2015). Seeing through the dark: New insights into the immune regulatory functions of vitamin A. Eur J Immunol 45(5): 1287-1295. Castellote, C., Casillas, R., Ramirez-Santana, C., Perez-Cano, F. J., Castell, M., Moretones, M. G., et al. (2011). Premature delivery influences the immunological composition of colostrum and transitional and mature human milk. J Nutr 141(6): 1181-1187. Chang, A., Robison, R., Cai, M. and Singh, A. M. (2016). Natural history of food-triggered atopic dermatitis and development of immediate reactions in children. J Allergy Clin Immunol Pract 4(2): 229-236 e221. Chen, S., Sims, G. P., Chen, X. X., Gu, Y. Y. and Lipsky, P. E. (2007). Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation. J Immunol 179(3): 1634-1647. Cheng, H. M., Kim, S., Park, G. H., Chang, S. E., Bang, S., Won, C. H., et al. (2014). Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population. J Allergy Clin Immunol 133(4): 1048-1055. Combs, G. F. (2008). The vitamins – Fundamental aspect in nutrition and health. Conradi, S., Malzahn, U., Paul, F., Quill, S., Harms, L., Then Bergh, F., et al. (2013). Breastfeeding is associated with lower risk for multiple sclerosis. Mult Scler 19(5): 553-558. Consensus Report of the European Task Force on Atopic Dermatitis. (1993). Severity scoring of atopic dermatitis: the SCORAD index. Dermatology 186(1): 23-31. de Pee, S. and Dary, O. (2002). Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. J Nutr 132(9 Suppl): 2895S-2901S. Dogruel, D., Bingol, G., Altintas, D. U., Yilmaz, M. and Kendirli, S. G. (2016). Prevalence of and risk factors for atopic dermatitis: A birth cohort study of infants in southeast Turkey. Allergol Immunopathol (Madr) 44(3): 214-220. Elias, K. M., Laurence, A., Davidson, T. S., Stephens, G., Kanno, Y., Shevach, E. M., et al. (2008). Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111(3): 1013-1020. Fujita, M., Roth, E., Lo, Y. J., Hurst, C., Vollner, J. and Kendell, A. (2012). In poor families, mothers' milk is richer for daughters than sons: a test of Trivers-Willard hypothesis in agropastoral settlements in Northern Kenya. Am J Phys Anthropol 149(1): 52-59. Garritsen, F. M., Brouwer, M. W., Limpens, J. and Spuls, P. I. (2014). Photo(chemo)therapy in the management of atopic dermatitis: an updated systematic review with implications for practice and research. Br J Dermatol 170(3): 501-513. Gdalevich, M., Mimouni, D., David, M. and Mimouni, M. (2001). Breast-feeding and the onset of atopic dermatitis in childhood: a systematic review and meta-analysis of prospective studies. J Am Acad Dermatol 45(4): 520-527. Gidrewicz, D. A. and Fenton, T. R. (2014). A systematic review and meta-analysis of the nutrient content of preterm and term breast milk. BMC Pediatr 14: 216. Gillman, M. W. (2005). Developmental origins of health and disease. N Engl J Med 353(17): 1848-1850. Giwercman, C., Halkjaer, L. B., Jensen, S. M., Bonnelykke, K., Lauritzen, L. and Bisgaard, H. (2010). Increased risk of eczema but reduced risk of early wheezy disorder from exclusive breast-feeding in high-risk infants. J Allergy Clin Immunol 125(4): 866-871. Goldman, A. S. and Goldblum, R. M. (1997). Transfer of maternal leukocytes to the infant by human milk. Curr Top Microbiol Immunol 222: 205-213. Goldman, A. S., Hopkinson, J. M. and Rassin, D. K. (2007). Benefits and risks of breastfeeding. Adv Pediatr 54: 275-304. Grant, W. B. and Holick, M. F. (2005). Benefits and requirements of vitamin D for optimal health: a review. Altern Med Rev 10(2): 94-111. Green, M. H., Green, J. B., Akohoue, S. A. and Kelley, S. K. (2001). Vitamin A intake affects the contribution of chylomicrons vs. retinol-binding protein to milk vitamin A in lactating rats. J Nutr 131(4): 1279-1282. Gregori, S., Casorati, M., Amuchastegui, S., Smiroldo, S., Davalli, A. M. and Adorini, L. (2001). Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 167(4): 1945-1953. Gurlek, A., Pittelkow, M. R. and Kumar, R. (2002). Modulation of growth factor/cytokine synthesis and signaling by 1alpha,25-dihydroxyvitamin D(3): implications in cell growth and differentiation. Endocr Rev 23(6): 763-786. Hartmann, B., Heine, G., Babina, M., Steinmeyer, A., Zugel, U., Radbruch, A., et al. (2011). Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response. Allergy 66(4): 540-548. Hassiotou, F., Hepworth, A. R., Metzger, P., Tat Lai, C., Trengove, N., Hartmann, P. E., et al. (2013). Maternal and infant infections stimulate a rapid leukocyte response in breastmilk. Clin Transl Immunology 2(4): e3. Hewison, M. (2011). Vitamin D and innate and adaptive immunity. Vitam Horm 86: 23-62. Hewison, M., Freeman, L., Hughes, S. V., Evans, K. N., Bland, R., Eliopoulos, A. G., et al. (2003). Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells. J Immunol 170(11): 5382-5390. Houghton, L. A. and Vieth, R. (2006). The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr 84(4): 694-697. Hozyasz, K. K., Chelchowska, M., Laskowska-Klita, T., Ruszkowska, L. and Milanowski, A. (2004). [Low concentration of alpha-tocopherol in erythrocytes of atopic dermatitis patients]. Med Wieku Rozwoj 8(4 Pt 1): 963-969. Hwang, C. Y., Chen, Y. J., Lin, M. W., Chen, T. J., Chu, S. Y., Chen, C. C., et al. (2010). Prevalence of atopic dermatitis, allergic rhinitis and asthma in Taiwan: a national study 2000 to 2007. Acta Derm Venereol 90(6): 589-594. Ichikawa, M., Sugita, M., Takahashi, M., Satomi, M., Takeshita, T., Araki, T., et al. (2003). Breast milk macrophages spontaneously produce granulocyte-macrophage colony-stimulating factor and differentiate into dendritic cells in the presence of exogenous interleukin-4 alone. Immunology 108(2): 189-195. Indumathi, S., Dhanasekaran, M., Rajkumar, J. S. and Sudarsanam, D. (2013). Exploring the stem cell and non-stem cell constituents of human breast milk. Cytotechnology 65(3): 385-393. Irene, N. T. and Jaykumary, M. M. (2010). How Significant is Family History in Atopic Dermatitis? A study on the role of family history in atopic dermatitis in children in ajman, united arab emirates. Egyptian Dermatology Online Journal 6(2): 4. Ismail, I. H., Licciardi, P. V., Oppedisano, F., Boyle, R. J. and Tang, M. L. (2013). Relationship between breast milk sCD14, TGF-beta1 and total IgA in the first month and development of eczema during infancy. Pediatr Allergy Immunol 24(4): 352-360. Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C. and Song, S. Y. (2004). Retinoic acid imprints gut-homing specificity on T cells. Immunity 21(4): 527-538. Jain, L., Vidyasagar, D., Xanthou, M., Ghai, V., Shimada, S. and Blend, M. (1989). In vivo distribution of human milk leucocytes after ingestion by newborn baboons. Arch Dis Child 64(7 Spec No): 930-933. Jenness, R. (1979). The composition of human milk. Semin Perinatol 3(3): 225-239. Jepsen, A. A., Chawes, B. L., Carson, C. G., Schoos, A. M., Thysen, A. H., Waage, J., et al. (2016). High breast milk IL-1beta level is associated with reduced risk of childhood eczema. Clin Exp Allergy. Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walters, P. (2002). Molecular Biology of the Cell. Joshi, D., Center, J. R. and Eisman, J. A. (2010;). Vitamin D deficiency in adults. Aust Prescr 33: 103-106. Julia, V., Macia, L. and Dombrowicz, D. (2015). The impact of diet on asthma and allergic diseases. Nat Rev Immunol 15(5): 308-322. Kadaoui, K. A. and Corthesy, B. (2007). Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment. J Immunol 179(11): 7751-7757. Kamao, M., Tsugawa, N., Suhara, Y. and Okano, T. (2007). Determination of Fat-soluble vitamins in human plasma, breast milk and food samples: application in nutrition survey for establishment of “dietary reference intakes for japanese”. J Health Sci 53(3): 257-262. Kasalova, E., Aufartova, J., Krcmova, L. K., Solichova, D. and Solich, P. (2015). Recent trends in the analysis of vitamin D and its metabolites in milk--a review. Food Chem 171: 177-190. Kim, S. Y., Sim, S., Park, B., Kim, J. H. and Choi, H. G. (2016). High-Fat and Low-carbohydrate diets are associated with allergic rhinitis but not asthma or atopic dermatitis in children. PLoS One 11(2): e0150202. Klement, E., Cohen, R. V., Boxman, J., Joseph, A. and Reif, S. (2004). Breastfeeding and risk of inflammatory bowel disease: a systematic review with meta-analysis. Am J Clin Nutr 80(5): 1342-1352. Klevor, M. K., Haskell, M. J., Lartey, A., Adu-Afarwuah, S., Zeilani, M. and Dewey, K. G. (2016). Lipid-based nutrient supplements providing approximately the recommended daily intake of vitamin a do not increase breast milk retinol concentrations among ghanaian women. J Nutr 146(2): 335-342. Koch, C., Dolle, S., Metzger, M., Rasche, C., Jungclas, H., Ruhl, R., et al. (2008). Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial. Br J Dermatol 158(4): 786-792. Komine, M., Watabe, Y., Shimaoka, S., Sato, F., Kake, K., Nishina, H., et al. (1999). The action of a novel vitamin D3 analogue, OCT, on immunomodulatory function of keratinocytes and lymphocytes. Arch Dermatol Res 291(9): 500-506. Kuby, J. (2007). Immunology. Kucerova, B., Krcmova, L., Solichova, D., Plisek, J. and Solich, P. (2013). Comparison of a new high-resolution monolithic column with core-shell and fully porous columns for the analysis of retinol and alpha-tocopherol in human serum and breast milk by ultra-high-performance liquid chromatography. J Sep Sci 36(14): 2223-2230. Kull, I., Bohme, M., Wahlgren, C. F., Nordvall, L., Pershagen, G. and Wickman, M. (2005). Breast-feeding reduces the risk for childhood eczema. J Allergy Clin Immunol 116(3): 657-661. Kulski, J. K. and Hartmann, P. E. (1981). Changes in human milk composition during the initiation of lactation. Aust J Exp Biol Med Sci 59(1): 101-114. Kunz, B., Oranje, A. P., Labreze, L., Stalder, J. F., Ring, J. and Taieb, A. (1997). Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology 195(1): 10-19. Lamni-Keefe, C. J., Couch, S. C. and Philipson, E. H. (2008). Handbook of nutrition and pregnancy. Laske, N. and Niggemann, B. (2004). Does the severity of atopic dermatitis correlate with serum IgE levels? Pediatr Allergy Immunol 15(1): 86-88. Lemire, J. M., Archer, D. C., Beck, L. and Spiegelberg, H. L. (1995). Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. J Nutr 125(6 Suppl): 1704S-1708S. Leung, D. Y., Boguniewicz, M., Howell, M. D., Nomura, I. and Hamid, Q. A. (2004). New insights into atopic dermatitis. J Clin Invest 113(5): 651-657. Lund-Blix, N. A., Stene, L. C., Rasmussen, T., Torjesen, P. A., Andersen, L. F. and Ronningen, K. S. (2015). Infant feeding in relation to islet autoimmunity and type 1 diabetes in genetically susceptible children: the MIDIA Study. Diabetes Care 38(2): 257-263. Mahon, B. D., Wittke, A., Weaver, V. and Cantorna, M. T. (2003). The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells. J Cell Biochem 89(5): 922-932. McKenna, S. P. and Doward, L. C. (2008). Quality of life of children with atopic dermatitis and their families. Curr Opin Allergy Clin Immunol 8(3): 228-231. Minniti, F., Comberiati, P., Munblit, D., Piacentini, G. L., Antoniazzi, E., Zanoni, L., et al. (2014). Breast-milk characteristics protecting against allergy. Endocr Metab Immune Disord Drug Targets 14(1): 9-15. Mohr, S. B., Garland, C. F., Gorham, E. D. and Garland, F. C. (2008). The association between ultraviolet B irradiance, vitamin D status and incidence rates of type 1 diabetes in 51 regions worldwide. Diabetologia 51(8): 1391-1398. Mucida, D., Park, Y., Kim, G., Turovskaya, O., Scott, I., Kronenberg, M., et al. (2007). Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 317(5835): 256-260. Muehleisen, B. and Gallo, R. L. (2013). Vitamin D in allergic disease: shedding light on a complex problem. J Allergy Clin Immunol 131(2): 324-329. Mutgi, K. and Koo, J. (2013). Update on the role of systemic vitamin D in atopic dermatitis. Pediatr Dermatol 30(3): 303-307. Nakamura, Y., Miyata, M., Ando, T., Shimokawa, N., Ohnuma, Y., Katoh, R., et al. (2009). The latent form of transforming growth factor-beta administered orally is activated by gastric acid in mice. J Nutr 139(8): 1463-1468. Newson, R. B., Shaheen, S. O., Henderson, A. J., Emmett, P. M., Sherriff, A. and Calder, P. C. (2004). Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema. J Allergy Clin Immunol 114(3): 531-537. Novak, N. and Bieber, T. (2003). Allergic and nonallergic forms of atopic diseases. J Allergy Clin Immunol 112(2): 252-262. Novak, N. and Bieber, T. (2005). The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis. J Am Acad Dermatol 53(2 Suppl 2): S171-176. Nurmatov, U., Devereux, G. and Sheikh, A. (2011). Nutrients and foods for the primary prevention of asthma and allergy: systematic review and meta-analysis. J Allergy Clin Immunol 127(3): 724-733 e721-730. Nutten, S. (2015). Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab 66 Suppl 1: 8-16. O'Byrne, S. M. and Blaner, W. S. (2013). Retinol and retinyl esters: biochemistry and physiology. J Lipid Res 54(7): 1731-1743. Ochiai, S., Shimojo, N., Morita, Y., Tomiita, M., Arima, T., Inoue, Y., et al. (2013). Cytokine biomarker candidates in breast milk associated with the development of atopic dermatitis in 6-month-old infants. Int Arch Allergy Immunol 160(4): 401-408. Oddy, W. H., Holt, P. G., Sly, P. D., Read, A. W., Landau, L. I., Stanley, F. J., et al. (1999). Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study. BMJ 319(7213): 815-819. Oh, S. Y., Chung, J., Kim, M. K., Kwon, S. O. and Cho, B. H. (2010). Antioxidant nutrient intakes and corresponding biomarkers associated with the risk of atopic dermatitis in young children. Eur J Clin Nutr 64(3): 245-252. Oien, T., Storro, O. and Johnsen, R. (2010). Do early intake of fish and fish oil protect against eczema and doctor-diagnosed asthma at 2 years of age? A cohort study. J Epidemiol Community Health 64(2): 124-129. Olliver, M., Spelmink, L., Hiew, J., Meyer-Hoffert, U., Henriques-Normark, B. and Bergman, P. (2013). Immunomodulatory effects of vitamin D on innate and adaptive immune responses to Streptococcus pneumoniae. J Infect Dis 208(9): 1474-1481. Oren, E., Banerji, A. and Camargo, C. A., Jr. (2008). Vitamin D and atopic disorders in an obese population screened for vitamin D deficiency. J Allergy Clin Immunol 121(2): 533-534. Parigi, S. M., Eldh, M., Larssen, P., Gabrielsson, S. and Villablanca, E. J. (2015). Breast Milk and Solid Food Shaping Intestinal Immunity. Front Immunol 6: 415. Penttila, I. A. (2010). Milk-derived transforming growth factor-beta and the infant immune response. J Pediatr 156(2 Suppl): S21-25. Perez de Lema, G., Lucio-Cazana, F. J., Molina, A., Luckow, B., Schmid, H., de Wit, C., et al. (2004). Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease. Kidney Int 66(3): 1018-1028. Peroni, D. G., Piacentini, G. L., Cametti, E., Chinellato, I. and Boner, A. L. (2011). Correlation between serum 25-hydroxyvitamin D levels and severity of atopic dermatitis in children. Br J Dermatol 164(5): 1078-1082. Pesonen, M., Kallio, M. J., Siimes, M. A. and Ranki, A. (2007). Retinol concentrations after birth are inversely associated with atopic manifestations in children and young adults. Clin Exp Allergy 37(1): 54-61. Plum, L. A. and DeLuca, H. F. (2010). Vitamin D, disease and therapeutic opportunities. Nat Rev Drug Discov 9(12): 941-955. Ross, A. C., Chen, Q. and Ma, Y. (2011). Vitamin A and retinoic acid in the regulation of B-cell development and antibody production. Vitam Horm 86: 103-126. Rudloff, S., Niehues, T., Rutsch, M., Kunz, C. and Schroten, H. (1999). Inflammation markers and cytokines in breast milk of atopic and nonatopic women. Allergy 54(3): 206-211. Saint, L., Smith, M. and Hartmann, P. E. (1984). The yield and nutrient content of colostrum and milk of women from giving birth to 1 month post-partum. Br J Nutr 52(1): 87-95. Saito, K., Yokoyama, T., Miyake, Y., Sasaki, S., Tanaka, K., Ohya, Y., et al. (2010). Maternal meat and fat consumption during pregnancy and suspected atopic eczema in Japanese infants aged 3-4 months: the Osaka Maternal and Child Health Study. Pediatr Allergy Immunol 21(1 Pt 1): 38-46. Sakurai, T., Furukawa, M., Asoh, M., Kanno, T., Kojima, T. and Yonekubo, A. (2005). Fat-soluble and water-soluble vitamin contents of breast milk from Japanese women. J Nutr Sci Vitaminol (Tokyo) 51(4): 239-247. Samur, G., Topcu, A. and Turan, S. (2009). Trans fatty acids and fatty acid composition of mature breast milk in turkish women and their association with maternal diet's. Lipids 44(5): 405-413. Sanclemente, T., Marques-Lopes, I., Puzo, J. and Garcia-Otin, A. L. (2009). Role of naturally-occurring plant sterols on intestinal cholesterol absorption and plasmatic levels. J Physiol Biochem 65(1): 87-98. Segaert, S. (2008). Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology? J Invest Dermatol 128(4): 773-775. Shaheen, S. O., Newson, R. B., Henderson, A. J., Emmett, P. M., Sherriff, A. and Cooke, M. (2004). Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema. Eur Respir J 24(2): 292-297. Sheldrake, R. F. and Husband, A. J. (1985). Intestinal uptake of intact maternal lymphocytes by neonatal rats and lambs. Res Vet Sci 39(1): 10-15. Snijders, B. E., Thijs, C., Dagnelie, P. C., Stelma, F. F., Mommers, M., Kummeling, I., et al. (2007). Breast-feeding duration and infant atopic manifestations, by maternal allergic status, in the first 2 years of life (KOALA study). J Pediatr 151(4): 347-351, 351 e341-342. Sokolovski, I. B. (2010). Atopic dermatitis and family history of allergic diseases in asthmatic and no asthmatic children. Pediatric Research 2010(68): 360. Stephensen, C. B. (2001). Vitamin A, infection, and immune function. Annu Rev Nutr 21: 167-192. Sun, J. (2010). Vitamin D and mucosal immune function. Curr Opin Gastroenterol 26(6): 591-595. Tariq, S. M., Matthews, S. M., Hakim, E. A., Stevens, M., Arshad, S. H. and Hide, D. W. (1998). The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study. J Allergy Clin Immunol 101(5): 587-593. Thiele, D. K., Senti, J. L. and Anderson, C. M. (2013). Maternal vitamin D supplementation to meet the needs of the breastfed infant: a systematic review. J Hum Lact 29(2): 163-170. Tomiya, M. T., de Arruda, I. K., da Silva Diniz, A., Santana, R. A., da Silveira, K. C. and Andreto, L. M. (2015). The effect of vitamin A supplementation with 400 000 IU vs 200 000 IU on retinol concentrations in the breast milk: A randomized clinical trial. Clin Nutr. doi: 10.1016. Turck, D. (2005). [Breast feeding: health benefits for child and mother]. Arch Pediatr 12 Suppl 3: S145-165. Turfkruyer, M. and Verhasselt, V. (2015). Breast milk and its impact on maturation of the neonatal immune system. Curr Opin Infect Dis 28(3): 199-206. Verhasselt, V., Milcent, V., Cazareth, J., Kanda, A., Fleury, S., Dombrowicz, D., et al. (2008). Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma. Nat Med 14(2): 170-175. vieth Streym, S., Hojskov, C. S., Moller, U. K., Heickendorff, L., Vestergaard, P., Mosekilde, L., et al. (2016). Vitamin D content in human breast milk: a 9-mo follow-up study. Am J Clin Nutr 103(1): 107-114. Wall, C. R., Stewart, A. W., Camargo, C. A., Jr., Scragg, R., Mitchell, E. A., Ekeroma, A., et al. (2016). Vitamin D activity of breast milk in women randomly assigned to vitamin D3 supplementation during pregnancy. Am J Clin Nutr 103(2): 382-388. Weiland, S. K., Husing, A., Strachan, D. P., Rzehak, P. and Pearce, N. (2004). Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children. Occup Environ Med 61(7): 609-615. Wetzig, H., Schulz, R., Diez, U., Herbarth, O., Viehweg, B. and Borte, M. (2000). Associations between duration of breast-feeding, sensitization to hens' eggs and eczema infantum in one and two year old children at high risk of atopy. Int J Hyg Environ Health 203(1): 17-21. Willett, W. C., Howe, G. R. and Kushi, L. H. (1997). Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr 65(4 Suppl): 1220S-1228S; discussion 1229S-1231S. Williams, H., Stewart, A., von Mutius, E., Cookson, W. and Anderson, H. R. (2008). Is eczema really on the increase worldwide? J Allergy Clin Immunol 121(4): 947-954 e915. Xanthou, M. (1998). Immune protection of human milk. Biol Neonate 74(2): 121-133. Xiao, S., Jin, H., Korn, T., Liu, S. M., Oukka, M., Lim, B., et al. (2008). Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J Immunol 181(4): 2277-2284. Yagi, Y., Watanabe, E., Watari, E., Shinya, E., Satomi, M., Takeshita, T., et al. (2010). Inhibition of DC-SIGN-mediated transmission of human immunodeficiency virus type 1 by Toll-like receptor 3 signalling in breast milk macrophages. Immunology 130(4): 597-607. Yasmin, R., Williams, R. M., Xu, M. and Noy, N. (2005). Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer. J Biol Chem 280(48): 40152-40160. Zhang, J. Y., Lucey, A. J., Galvin, K., Nolan, L., Cashman, K. D., Higgins, J. R., et al. (2012). Vitamin D content of human milk and associations with milk fat content and maternal serum 25-hydroxyvitamin D concentrations. Pro Nutri Soc 71(OCE2): E54. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/78144 | - |
dc.description.abstract | 異位性皮膚炎 (atopic dermatitis, atopic eczema) 為常見過敏性皮膚炎疾病,全球約有15-20%孩童及1-3%成人罹患此病。近年來免疫相關疾病的研究指出,飲食為異位性皮膚炎罹患風險及嚴重程度的影響因子。維生素A與D具有免疫調節作用,國人維生素A與D攝取有缺乏之虞,維生素A與D的營養狀況與過敏疾病發生率是否有關聯性,值得探討。已知哺乳能降低嬰兒異位性皮膚炎罹患率,然而近年門診發現異位性皮膚炎嬰兒也多有哺餵母乳,因此,推測是否與母乳的營養成分有關。故本研究目的為探討嬰兒異位性皮膚炎是否與母乳的營養素的含量有關,尤其是維生素A和D3。本研究與台大醫院小兒科過敏門診合作,收募受試者為六個月齡以下異位性皮膚炎嬰兒48位為病例組,健康嬰兒47位作為控制組,測定母親之母乳的 retinol、25-hydroxyvitamin D3 (25-(OH) D3) 及細胞激素含量,並對母親進行一個月的飲食頻率問卷調查。結果顯示,母親的鉀、鋅、維生素B1、菸鹼素、維生素B6及酒精攝取量,與嬰兒的SCORAD呈顯著正相關。中重度AD組的母親熱量攝取較health組少,與輕度AD組相比,母親的鋅、維生素B1及膽固醇攝取量較高。此外,中重度AD組的母乳25-(OH) D3與TGF-β含量顯著低於health組,而母乳retinol含量有較輕度AD組低的趨勢。綜合以上,六個月齡以下嬰兒所攝取母乳的維生素D及TGF-β含量越少,可能增加嬰兒罹患異位性皮膚炎的風險及嚴重程度。 | zh_TW |
dc.description.abstract | Atopic dermatitis, also known as atopic eczema, is a common allergic skin disease. There are 15-20% children and 1-3% adults suffer from atopic dermatitis all over the world. Some studies showed that diet affects the risk and severity of atopic dermatitis. It had been known that vitamin A and D regulate immune response. There are high proportion of people have the status of vitamin A and D deficiency in Taiwan, while the correlation between the vitamins and incidences of allergic diseases is still unclear. Also, studies had showed that breastfeeding can lower the risk of atopic dermatitis. However, there are many breastfed infants suffer from atopic dermatitis nowadays, we hypothesize that breast milk nutrition might affect the morbidity rate and severe of atopic dermatitis. Therefore, the aim of this research is to investigate the association between human breast milk vitamin levels and atopic dermatitis status. We cooperate with the department of the pediatric allergy at NTU hospital. There are 48 infants with atopic dermatitis and 47 health infants who are under 6-months of age participated in this research, we collected breast milk from all infants’ mothers to detect retinol, 25-hydroxyvitamin D3 (25-(OH) D3) and cytokine levels, and we also analyzed maternal diet by FFQ (food frequency questionnaire). Results showed that the correlation between K, Zn, vitamin B1, niacin or alcohol from maternal diet in AD group and SCORAD (SCORing Atopic Dermatitis) were significantly positive. The moderate-AD group took less energy than the health group did, but it took more in Zn, vitamin B1 and cholesterol than the mild-AD group did. In addition, breast milk 25-(OH) D3 and TGF-β levels in the moderate-AD group were significantly lower than they were in the health group. We also found that breast milk retinol levels in the moderate-AD group were lower than they were in the mild-AD group. In conclusion, if the infants under 6 months of age take lower breast milk 25-(OH) D3 and TGF-β, it might increase the risk and severe of atopic dermatitis. | en |
dc.description.provenance | Made available in DSpace on 2021-07-11T14:43:40Z (GMT). No. of bitstreams: 1 ntu-105-R03b22020-1.pdf: 3160835 bytes, checksum: f427ba1e9ece32a066a346c8cb4f4948 (MD5) Previous issue date: 2016 | en |
dc.description.tableofcontents | 目錄
口試委員會審定書 i 摘要 ii Abstract iii 圖目錄 vi 表目錄 vii 縮寫對照表 viii 第一章、緒論 1 第一節、文獻回顧 1 一、異位性皮膚炎 1 二、母乳 7 三、維生素A 9 四、維生素D 13 第二節、研究動機與架構 19 第二章、材料與方法 21 第一節、母親飲食頻率問卷調查 21 一、研究對象及病情分數 21 二、飲食頻率問卷 (food frequency questionnaire, FFQ) 21 第二節、母乳的維生素A (retinol) 檢測與分析 22 一、檢體收集與處理 22 二、檢測方法 23 第三節、母乳的維生素D (25-(OH) D3)檢測與分析 24 一、檢體收集與處理 24 二、檢測方法 24 第四節、母乳的細胞激素檢測 27 一、檢體收集與處理 27 二、檢測方法 27 三、統計分析 28 第三章、結果與討論 29 第一節、母親飲食頻率問卷調查 29 一、嬰兒家族成員病史與異位性皮膚炎關聯性 29 二、母親營養攝取狀況 31 三、母親飲食與嬰兒異位性皮膚炎 33 第二節、母乳的維生素A 與D3含量 40 一、母乳的維生素A (retinol) 含量 40 二、母乳視網醇含量對嬰兒異位性皮膚炎影響 42 三、母乳的維生素D (25-(OH) D3) 含量 44 四、母乳25-(OH) D3含量對嬰兒異位性皮膚炎影響 46 第三節、母親飲食對母乳維生素A和D含量影響 48 第四節、母乳的細胞激素濃度 50 第四章、綜合討論與總結 54 第一節、實驗限制 54 第二節、綜合討論 54 一、母乳維生素D的方法檢測 54 二、嬰兒維生素A與D攝取狀況 55 三、飲食維生素D與母乳 56 第三節、總結 56 第五章、參考文獻 57 附錄 69 | |
dc.language.iso | zh-TW | |
dc.title | 母乳維生素A和D含量與嬰兒異位性皮膚炎關聯性之探討 | zh_TW |
dc.title | Study on association of human breast milk vitamin A and D levels with atopic dermatitis in the breastfed infants | en |
dc.type | Thesis | |
dc.date.schoolyear | 104-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 江伯倫,蘇南維,王麗潔,洪永瀚 | |
dc.subject.keyword | 異位性皮膚炎,母乳,維生素A,維生素D,TGF-β,母親飲食, | zh_TW |
dc.subject.keyword | atopic dermatitis,breast milk,vitamin A,vitamin D,TGF-β,maternal diet, | en |
dc.relation.page | 80 | |
dc.identifier.doi | 10.6342/NTU201602208 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2016-08-11 | |
dc.contributor.author-college | 生命科學院 | zh_TW |
dc.contributor.author-dept | 生化科技學系 | zh_TW |
顯示於系所單位: | 生化科技學系 |
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