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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/75494完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.author | Mei Chen | en |
| dc.contributor.author | 陳玫 | zh_TW |
| dc.date.accessioned | 2021-07-01T08:13:30Z | - |
| dc.date.available | 2021-07-01T08:13:30Z | - |
| dc.date.issued | 1983 | |
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Partial trisomy 14q- and parental translocation of No. 14 chromosome. J. Med. Genet., 14, 124-127. 51. Simpson, J. L. (1981). Antenatal diagnosis of cytogenetic abnormalities. In Clinical Obstetrics and Gynecology. 24(4), 1023-1039. (Simpson, J. L. and J. D. Thompson Eds.) 52. Smith, A., C.D. Dulk and C. Elliott (1980). A severely retarded 18-year-old boy with tertiary partial trisomy 14. J. Med. Cenet., 17, 230-232. 53. Smith, A. and C. Elliott (1980). Occurrence of sex chromosome mosaicism and translocation Down’s syndrome in the same family. Clinic. Cenet., 17, 341-348. 54. Stenchever, M.A., J. A. Jarvis and M. N. Maclntyre (1968). Cytogenetics of habitual abortion. Obstet. Gynecol., 32(4), 548-555. 55. Stenchever, M. A., K. J. Parks, T. L. Daines, M. A. Allen and M. R. Stenchever (1977). Cytogenetics of habitual abortion and other reproductive wastage. Amer. J. Obstet. Gynecol., 127(2), 143-150. 56. Stoll, C. (1980). Nonrandom distribution of exchange points in patients with reciprocal translocations. Hum. Genet., 56, 89-93. 57. Stoll, C. (1981). Cytogenetic findings in 122 couples with recurrent abortions. Hum. Genet., 57, 101-103. 58. Subrt, I. (1980). Reciprocal translocation with special.reference to reproductive failure. Hum. Genet., 55, 303-307. 59. Swanson, C. P., T. Merz, W. J. Young (1981). Variation : sources and consequences involving chromosome numbers. In Cytogenetics The Chromosome in Division, Inheritance and Evolution 2nd ed. Prentice-Hall, Inc., Englewood Cliffs. 60. Tsenghi, C., C. Metaxotou-stavridaki, M. Strataki-Benetou, A. Kalpini-Mavrou and Matsaniotis (1976). Chromosome studies in couples with repeated spontaneous abortions. Obstet. Gynecol., 47(4), 463-468. 61. Ward, B.E., G. P. Henry and A. Robinson (1980). Cytogenetic studies in 100 couples with recurrent spontaneous abortions. Am. J. Hum. Genet., 32, 549-554. 62. Wisniewski, K., M. Dambska, E. C. Jenkins, S. 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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/75494 | - |
| dc.description.abstract | 以吉氏紋帶染色法及固有異染色質染色法檢查重複性流產夫婦的核型及異常染色體的遺傳。 在35位重複性流產夫婦檢樣中發現兩例平衡的染色體相互轉位核型:(a) 46，XY，t(3；16)(3qter→3p2l::l6p12 →l6pter;l6qter →16p12::3p21→3pter)；及 (b) 46,XY,t(7;18)(7qter →7p14::18q23→l8qter;l8pter →18q23::7p14 →7pter)。 重複性流產夫婦中核型異常的頻率為 5 . 7 ％。配偶之一具有異常核型時，女性平衡轉位攜帶者的家庭較男性攜帶者的家庭有較高的懷孕成功率。 另一對無流產記錄的夫婦，其妻及女胎具平衡羅氏轉位核型 45 , XX, t (14 ; 21) (14qter→cen →21qter ) 。具羅氏轉位 t ( 14q2lq ）的家庭中，平衡轉位核型的子女多於正常核型者。 文中討論異常染色體的形成，重複性流產與核型異常，平衡轉位染色體攜帶者的性別與懷孕成功率及異常染色體的遺傳，並與相關文獻綜合比較。 | zh_TW |
| dc.description.abstract | G-banding and C-bonding techniques were employed to study the karyotype and the transmission of the aberrant chromosomes in recurrent aborters. Two cases of balanced autosomal reciprocal translocations were discovered: (a). 46,XY,t(3;16)(3qter →3p2l::l6p12 →l6pter;l6qter →16p12::3p21 →3pter) and (b). 46,XY,t(7;18)(7qter →7p14::18q23 →l8qter;l8pter →18q23::7p14 →7pter) in 35 studies. The frequency of chromosome anomalies in recurrent aborters is 5.7%. Female carriers of the aberrant chromosome revealed higher reproductive successes than male carriers. In a family with no spontaneous abortions, both the mother and the female fetus were carriers of a Robertsonian translocation chromosome, t(14q21q). Their karyotype is 45,XX,t(14;21)(l4qter-cen-2lqter). There were more balanced carriers than normal ones in the family with Rob.t(14q21q). The formation of aberrant chromosomes and chromosome anomaly in recurrent aborters were discussed. The reproductive performance and inheritance of the aberrant chromosomes in male and female carriers were analyzed and comparisons were made with others. | en |
| dc.description.provenance | Made available in DSpace on 2021-07-01T08:13:30Z (GMT). No. of bitstreams: 0 Previous issue date: 1983 | en |
| dc.description.tableofcontents | (Ⅰ) 前言…………………………………………………………………………………………………1 (Ⅱ) 材料與方法 (一) 淋巴球培養……………………………………………………………………………………3 (二) 有絲分裂細胞風乾片製備……………………………………………………………………4 (三) 染色體染色……………………………………………………………………………………5 (四) 染色體的觀察及記錄…………………………………………………………………………6 (Ⅲ) 結果 (一) 受檢人一般特徵………………………………………………………………………………7 (二) 受檢人的核型…………………………………………………………………………………7 (三) 轉位染色體的遺傳及其攜帶者的懷孕成功率………………………………………………10 (Ⅳ) 討論 (一) 異常染色體的形成……………………………………………………………………………13 (二) 重複性流產與核型異常………………………………………………………………………15 (三) 平衡轉位者的懷孕成功率……………………………………………………………………17 (四) 轉位染色體的遺傳……………………………………………………………………………20 (Ⅴ) 英文摘要………………………………………………………………………………………………24 (Ⅵ) 參考文獻………………………………………………………………………………………………25 | |
| dc.language.iso | zh-TW | |
| dc.title | 重複流產夫婦的異常染色體和其遺傳 | zh_TW |
| dc.title | Aberrant Chromosomes and Their Transmissions in Couples with Recurrent Abortions | en |
| dc.date.schoolyear | 71-2 | |
| dc.description.degree | 碩士 | |
| dc.relation.page | 55 | |
| dc.rights.note | 未授權 | |
| dc.contributor.author-dept | 生命科學院 | zh_TW |
| dc.contributor.author-dept | 動物學研究所 | zh_TW |
| 顯示於系所單位： | 動物學研究所 | |
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