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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 陳立仁(Li-Jen Chen) | |
| dc.contributor.author | Zhi-Ting Liao | en |
| dc.contributor.author | 廖芝婷 | zh_TW |
| dc.date.accessioned | 2021-06-17T08:40:45Z | - |
| dc.date.available | 2026-01-19 | |
| dc.date.copyright | 2021-01-22 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-01-19 | |
| dc.identifier.citation | 1.Myers, D. Surfaces, interfaces, and colloids: principles and applications. Second edition, vol. 4, John Wiley Sons, Inc., (1999). 2.Li, Y., Chen, X., Zhang, M., Luo, W., Yang, J. Zhu, F. Macromolecular aggregation of aqueous polyacrylic acid in the presence of surfactants revealed by resonance rayleigh scattering. Macromolecules 41, 4873–4880 (2008). 3.Wang, X., Li, Y., Li, J,. Wang, J., Wang, Y., Guo, Z. Yan, H. Salt effect on the complex formation between polyelectrolyte and oppositely charged surfactant in aqueous solution. J. Phys. Chem. B 109, 10807–10812 (2005). 4.Nagarajan, R. Amphiphilic surfactants and amphiphilic polymers: Principles of molecular assembly. ACS Symp. Ser. 1070, 1–22 (2011). 5.Alexandridis, P. Alan Hatton, T. Poly(ethylene oxide)poly(propylene oxide)poly(ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure, dynamics, and modeling. Colloids Surfaces A Physicochem. Eng. Asp. 96, 1–46 (1995). 6.Liu, S., Hu, C., Huang, J. Yan, Y. Fluorescent polyion complex for the detection of sodium dodecylbenzenesulfonate. Polymers 10, 657–568 (2018). 7.Rosen, M. J. Kunjappu, J. T. Surfactants and interfacial phenomena. Fourth edition, John Wiley Sons, Inc., (2012). 8.Van der Meeren, P. Verstraetet, W. Surfactants in relation to bioremediation and wastewater treatment. Curr. Opin. Colloid Interface Sci. 1, 624–634 (1996). 9.Han, Y., Wei, Y., Wang, H., Mei, Y. Zhou, H. Contrasting the effects of hydrophobicity and counterion size on anionic wormlike micelle growth. J. Surfactants Deterg. 16, 139–145 (2013). 10.Dautzenberg, H. Polyelectrolyte complex formation in highly aggregating systems. 1. Effect of salt: Polyelectrolyte complex formation in the presence of NaCl. Macromolecules 30, 7810–7815 (1997). 11.Lindman, B., Antunes, F., Aidarova, S., Miguel, M. Nylander, T. Polyelectrolyte-surfactant association—from fundamentals to applications. Colloid J. 76, 585–594 (2014). 12.Pinotti, A., Bevilacqua, A. Zaritzky, N. Comparison of the performance of chitosan a cationic polyacrylamide as flocculants of emulsion systems. J. Surfactants Deterg. 4, 57–63 (2001). 13.Shulevich, Y. V., Nguyen, T. H., Tutaev, D. S., Navrotskii, A. V. Novakov, I. A. Purification of fat-containing wastewater using polyelectrolyte-surfactant complexes. Sep. Purif. Technol. 113, 18–23 (2013). 14.Petzold, G., Mende, M. Kochurova, N. Polymer-surfactant complexes as flocculants. Colloids Surfaces A Physicochem. Eng. Asp. 298, 139–144 (2007). 15.Goddard, E. D. Polymer/surfactant interaction-Its relevance to detergent systems. J. Am. Oil Chem. Soc. 71, 1–16 (1994). 16.Goddard, E. D. Polymer/surfactant interaction: Interfacial aspects. J. Colloid Interface Sci. 256, 228–235 (2002). 17.Llamas, S., Guzmán, E., Ortega, F., Baghdadli, N., Cazeneuve, C., Rubio, R. G. Luengo, G. S. Adsorption of polyelectrolytes and polyelectrolytes-surfactant mixtures at surfaces: A physico-chemical approach to a cosmetic challenge. Adv. Colloid Interface Sci. 222, 461–487 (2015). 18.Penfold, J., Thomas, R. K., Bradbury, R., Tucker, I., Petkov, J. T., Jones, C. W. Webster, J. R. P. Probing the surface of aqueous surfactant-perfume mixed solutions during perfume evaporation. Colloids Surfaces A Physicochem. Eng. Asp. 520, 178–183 (2017). 19.Zhang, P., Zheng, P. Y., Zhao, F. Y., An, Q. F. Gao, C. J. Preparation and pervaporation characteristics of novel ethanol permselective polyelectrolyte-surfactant complex membranes. RSC Adv. 5, 63545–63552 (2015). 20.Budhathoki, M., Barnee, S. H. R., Shiau, B. J. Harwell, J. H. Improved oil recovery by reducing surfactant adsorption with polyelectrolyte in high saline brine. Colloids Surfaces A Physicochem. Eng. Asp. 498, 66–73 (2016). 21.Aoudia, M. Zana, R. Aggregation behavior of sugar surfactants in aqueous solutions: Effects of temperature and the addition of nonionic polymers. J. Colloid Interface Sci. 206, 158–167 (1998). 22.Alargova, R., Petkov, J., Petsev, D., Ivanov, I. B., Broze, G. Mehreteab, A. Light scattering study of sodium dodecyl polyoxyethylene-2-sulfate micelles in the presence of multivalent counterions. Langmuir 11, 1530–1536 (1995). 23.Yardimci, H., Chung, B., Harden, J. L. Leheny, R. L. Phase behavior and local dynamics of concentrated triblock copolymer micelles. J. Chem. Phys. 123, 244908 (2005). 24.Liu, S. Li, L. Multiple phase transition and scaling law for poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer in aqueous solution. ACS Appl. Mater. Interfaces 7, 2688–2697 (2015). 25.Phillips, J. N. The energetics of micelle formation. Trans. Faraday Soc. 51, 561–569 (1955). 26.Chen, L. J., Lin, S. Y. Huang, C. C. Effect of hydrophobic chain length of surfactants on enthalpy-entropy compensation of micellization. J. Phys. Chem. B 102, 4350–4356 (1998). 27.Franks, F. Water: A comprehensive treatise: Volume 4: Aqueous solutions of amphiphiles and macromolecules. vol. 4, Plenum Press, (1975). 28.Paula, S., Süs, W., Tuchtenhagen, J. Blume, A. Thermodynamics of micelle formation as a function of temperature: A high sensitivity titration calorimetry study. J. Phys. Chem. 99, 11742–11751 (1995). 29.Seymour, K. G. Surfactants and interfacial phenomena. Third edition, vol. 62, John Wiley Sons, Inc., (1979). 30.Nakama, Y. Surfactants. Cosmetic science and technology: Theoretical principles and applications. Elsevier Inc., 231–244 (2017). 31.Roy, J. C., Islam, M. N. Aktaruzzaman, G. The effect of NaCl on the Krafft temperature and related behavior of cetyltrimethylammonium bromide in aqueous solution. J. Surfactants Deterg. 17, 231–242 (2014). 32.Ohta, A., Murakami, R., Takiue, T., Ikeda, N. Aratono, M. Calorimetric study of micellar solutions of pentaethylene glycol monooctyl and moriodecyl ethers. J. Phys. Chem. B 104, 8592–8597 (2000). 33.Lee, E. S., Lee, E. S., Oh, Y. T., Youn, Y. S., Nam, M., Park, B., Yun, J., Kim, J. H., Song, H. T. Oh, K. T. Binary mixing of micelles using Pluronics for a nano-sized drug delivery system. Colloids Surfaces B Biointerfaces 82, 190–195 (2011). 34.Danson, S., Ferry, D., Alakhov, V., Margison, J., Kerr, D., Jowle, D., Brampton, M., Halbert, G. Ranson, M. Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer. British Journal of Cancer 90, 2085–2091 (2004). 35.Matsumura, Y. Preclinical and clinical studies of anticancer drug-incorporated polymeric micelles. J. Drug Target. 15, 507–517 (2007). 36.Adhikari, U., Goliaei, A., Tsereteli, L. Berkowitz, M. L. Properties of poloxamer molecules and poloxamer micelles dissolved in water and next to lipid bilayers: Results from computer simulations. J. Phys. Chem. B 120, 5823–5830 (2016). 37.Basak, R. Bandyopadhyay, R. Encapsulation of hydrophobic drugs in pluronic F127 micelles: Effects of drug hydrophobicity, solution temperature, and pH. Langmuir 29, 4350–4356 (2013). 38.Chen, Y., Zhang, W., Gu, J., Ren, Q., Fan, Z., Zhong, W., Fang, X. Sha, X. Enhanced antitumor efficacy by methotrexate conjugated Pluronic mixed micelles against KBv multidrug resistant cancer. Int. J. Pharm. 452, 421–433 (2013). 39.Kadam, Y., Yerramilli, U. Bahadur, A. Solubilization of poorly water-soluble drug carbamezapine in Pluronic® micelles: Effect of molecular characteristics, temperature and added salt on the solubilizing capacity. Colloids Surfaces B Biointerfaces 72, 141–147 (2009). 40.Gaisford, S., Beezer, A. E. Mitchell, J. C. Diode-array UV spectrometric evidence for cooperative interactions in binary mixtures of pluronics F77, F87, and F127. Langmuir 13, 2606–2607 (1997). 41.Oh, K. T., Bronich, T. K. Kabanov, A.V. Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers. J. Control. Release 94, 411–422 (2004). 42.Wei, Z., Hao, J., Yuan, S., Li, Y., Juan, W., Sha, X. Fang, X. Paclitaxel-loaded Pluronic P123/F127 mixed polymeric micelles: Formulation, optimization and in vitro characterization. Int. J. Pharm. 376, 176–185 (2009). 43.Zhang, M., Djabourov, M., Bourgaux, C. Bouchemal, K. Nanostructured fluids from pluronic® mixtures. Int. J. Pharm. 454, 599–610 (2013). 44.Pragatheeswaran, A. M., Chen, S. B., Chen, C. F. Chen, B. H. Micellization and gelation of PEO-PPO-PEO binary mixture with non-identical PPO block lengths in aqueous solution. Polymer 55, 5284–5291 (2014). 45.Meznarich, N. A. K., Juggernauth, K. A., Batzli, K. M. Love, B. J. Structural changes in PEO-PPO-PEO gels induced by methylparaben and dexamethasone observed using time-resolved SAXS. Macromolecules 44, 7792–7798 (2011). 46.Drummond, C. J. Fong, C. Surfactant self-assembly objects as novel drug delivery vehicles. Curr. Opin. Colloid Interface Sci. 4, 449–456 (1999). 47.Kaasgaard, T. Drummond, C. J. Ordered 2-D and 3-D nanostructured amphiphile self-assembly materials stable in excess solvent. Phys. Chem. Chem. Phys. 8, 4957–4975 (2006). 48.Negrini, R. Mezzenga, R. PH-responsive lyotropic liquid crystals for controlled drug delivery. Langmuir 27, 5296–5303 (2011). 49.Yang, Y., Wang, J. C., Zhang, X., Lu, W. L. Zhang, Q. A novel mixed micelle gel with thermo-sensitive property for the local delivery of docetaxel. J. Control. Release 135, 175–182 (2009). 50.Meznarich, N. A. K. Love, B. J. The kinetics of gel formation for PEO-PPO-PEO triblock copolymer solutions and the effects of added methylparaben. Macromolecules 44, 3548–3555 (2011). 51.Dobrynin, A.V. Rubinstein, M. Theory of polyelectrolytes in solutions and at surfaces. Prog. Polym. Sci. 30, 1049–1118 (2005). 52.Macknight, W. J., Ponomarenko, E. A. Tirrell, D. A. Self-assembled polyelectrolyte - surfactant complexes in nonaqueous solvents and in the solid state. Acc. Chem. Res. 31, 781–788 (1998). 53.Kabanov, V. A., Zezin, A. B., Kasaikin, V. A., Zakharova, J. A., Litmanovich, E. A. Ivleva, E. M. Self-assembly of ionic amphiphiles on polyelectrolyte chains. Polym. Int. 52, 1566–1572 (2003). 54.Lim, P. F. C., Chee, L. Y., Chen, S. B. Chen, B. H. Study of interaction between cetyltrimethylammonium bromide and poly(acrylic acid) by rheological measurements. J. Phys. Chem. B 107, 6491–6496 (2003). 55.Wang, C. Tam, K. C. New insights on the interaction mechanism within oppositely charged polymer/surfactant systems. Langmuir 18, 6484–6490 (2002). 56.Pojjaźk, K., Bertalanits, E. Meźszaźros, R. Effect of salt on the equilibrium and nonequilibrium features of polyelectrolyte/surfactant association. Langmuir 27, 9139–9147 (2011). 57.Wang, C. Tam, K. C. Interactions between poly(acrylic acid) and sodium dodecyl sulfate: Isothermal titration calorimetric and surfactant ion-selective electrode studies. J. Phys. Chem. B 109, 5156–5161 (2005). 58.Bromberg, L., Temchenko, M. Colby, R. H. Interactions among hydrophobically modified polyelectrolytes and surfactants of the same charge. Langmuir 16, 2609–2614 (2000). 59.Zhang, C., Geng, T., Jiang, Y., Zhao, L., Ju, H. Wang, Y. Impact of NaCl concentration on equilibrium and dynamic surface adsorption of cationic surfactants in aqueous solution. J. Mol. Liq. 238, 423–429 (2017). 60.Tseng, H. W., Chen, P. C., Tsui, H. W., Wang, C. H., Hu, T. Y. Chen, L. J. Effect of molecular weight of poly(acrylic acid) on the interaction of oppositely charged ionic surfactant–polyelectrolyte mixtures. J. Taiwan Inst. Chem. Eng. 92, 50–57 (2018). 61.Park, M. J., Char, K., Kim, H. D., Lee, C. H., Seong, B. S. Han, Y. S. Phase behavior of a peo-ppo-peo triblock copolymer in aqueous solutions: Two gelation mechanisms. Macromol. Res. 10, 325–331 (2002). 62.Lee, C. F., Wang, M. R., Lin, T. L., Yang, C. H. Chen, L. J. Dynamic behavior of the structural phase transition of hydrogel formation induced by temperature ramp and addition of ibuprofen. Langmuir 36, 8929–8938 (2020). 63.陳柏嘉, 碩士學位論文, 聚丙烯酸與離子型界面活性劑作用之熱力學性質探討, 國立台灣大學化學工程研究所 2008 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/74526 | - |
| dc.description.abstract | 本研究主要分成兩部分，第一部分探討聚電解質/界面活性劑系統中的交互作用情形，第二部分探討界面活性劑Pluronics由溫度改變所引起水凝膠的生成行為。 在第一部份中，透過恆溫滴定熱卡計、表面張力儀以及電導度計研究聚電解質聚丙烯酸於半稀釋纏繞區間濃度下與陽離子型界面活性劑溴化十六烷基三甲銨 (C16TAB)添加鹽類後之間的交互作用，並改變系統溫度 (25 oC及35 oC)、鹽類濃度 (0.001 m及0.005 m)以及鹽類種類 (氯化鈉及溴化鈉)觀察其變化。我們發現當鹽類存在於聚電解質/界面活性劑 (PES)系統時，各特徵濃度會隨鹽類濃度上升而下降，但臨界聚集濃度 (CAC)則相反，另一方面，添加NaBr相對於NaCl對系統的影響較為劇烈，使單體分子排列更緊密，進而促使界面活性劑形成微胞。 第二部分中使用普朗尼克 (Pluronic)三段式共聚合物，因為其雙親性及生物可分解的特質，應用十分廣泛。本實驗研究高濃度共聚物溶液隨溫度升高疏水作用上升，促使微胞堆疊成水凝膠，我們使用Pluronic F108、F108+P103 (2:1)、F108+P103 (1:2)和P103皆在30 wt%濃度下研究由溫度改變所引起的水凝膠生成行為，有趣的是，30 wt% P103系統在不同溫度區間會出現兩個凝膠態，其獨特的相行為變化值得我們持續深入研究。除了巨觀的相行為變化外，同時也探討巨觀行為背後水凝膠晶相微觀結構的轉變，當升溫速度上升，系統凝膠化的範圍會縮小。另一方面，根據小角X光散射實驗 (SAXS)，不同升溫速度會影響水凝膠在不同溫度下的晶相結構變化，但晶體結構的整體轉變最終會趨於平衡態的結果。 | zh_TW |
| dc.description.abstract | This study is divided into two parts. The first part discusses the interaction between the polyelectrolyte/surfactant system, and the second part discusses the hydrogel formation behavior of the Pluronic induced by temperature changes. The first part of this work, we explore the effect of adding salt on the interaction between cationic surfactant and anionic polyelectrolyte in the semi-dilute unentangled regime through different techniques such as isothermal titration calorimetry, surface tensiometer and conductometry. We established three different perspectives to observe: system temperature (25 oC and 35 oC), salt concentration (0.001 m and 0.005 m) and the type of salt (NaCl and NaBr). It is found that the values of characteristic concentration decrease as the salts concentration increase except the critical aggregation concentration in the polyelectrolyte/surfactant system. On the other hand, the addition of NaBr effects the system more dramatically than NaCl, which makes the unimer molecules close packing and promote surfactant form into micelles. In the second part of this work, we use Pluronic, a series of amphiphilic and biodegradable tri-block copolymer, has been widely used. First, we study hydrogel formed by the packing of micelles in concentrated solution, raising temperature of the system induces the hydrophobic effect and promotes packing of micelles into hard gel. We focused on the temperature induced changes of gel formation using Pluronic F108, F108+P103 (2:1), F108+P103 (1:2) and P103 in the concentration of 30 wt%. Interestingly, 30 wt% P103 system shows apparent two gel states in different temperature region and its unique phase behavior changes are worthy of further study. In addition to the changes of macroscopic phase behavior, the transformation of the hydrogel crystal phase microstructure behind the macroscopic behavior is also discussed. As heating rate increases, gelation window becomes smaller. On the other hand, according to the small-angle X-ray scattering experiment (SAXS), different heating rates lead to microstructural changes of crystalline structure at different temperatures, but all the structural evolutions are the continuous process toward equilibration for hydrogel. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-17T08:40:45Z (GMT). No. of bitstreams: 1 U0001-1901202115504700.pdf: 9090874 bytes, checksum: 2059e3f293fedf63d1128b7e9b4d1d9f (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 口試委員會審定書 i 誌謝 ii 摘要 iv ABSTRACT v 目 錄 vii 表目錄 x 圖目錄 xi 第一章 緒論 1 第二章 文獻回顧 8 2.1 界面活性劑與微胞 8 2.1.1 界面活性劑形成微胞之機制 8 2.1.2 Pluronic 形成微胞之機制 9 2.1.3 臨界微胞濃度和臨界微胞溫度 9 2.1.4 影響微胞化過程的因素 10 2.2 微胞化過程之熱力學模型 13 2.2.1 相變模型 13 2.2.2 由ITC實驗分析微胞化過程 15 2.3 雙成分Pluronic系統 17 2.4 Pluronic 水凝膠 19 2.5 聚電解質/界面活性劑系統 20 2.5.1 帶相反電性之聚電解質/界面活性劑系統 21 2.5.2 帶相同電性之聚電解質/界面活性劑系統 26 2.6 表面張力之探討 26 第三章 實驗設備及方法 29 3.1 實驗藥品 29 3.2 實驗方法 30 3.2.1 恆溫滴定熱卡計 (ITC) 34 3.2.2 表面張力儀 36 3.2.3 導電度計 38 3.2.4 界面電位分析儀 38 3.2.5 高感度微分掃描式熱卡計 (HSDSC) 39 3.2.6 管反轉法 (Tube Inversion) 42 3.2.7 流變儀 42 3.2.8 小角X光散射 (SAXS) 42 第四章 PAA/C16TAB添加鹽類系統 43 4.1 恆溫滴定熱卡計 (ITC)數據處理 43 4.1.1 ITC實驗數據的理論與計算 43 4.1.2 ITC積分基線的決定 44 4.1.3 微胞化過程之臨界微胞濃度及熱焓變化的計算 44 4.1.4 PES系統添加鹽類之交互作用探討與熱力學性質判定 46 4.2 表面張力數據處理 48 4.3 電導度量測之臨界微胞濃度和解離度的決定方法 49 4.4 PAA+C16TAB添加鹽類系統結果討論 50 4.4.1 PAA+C16TAB添加鹽類系統ITC結果討論 50 4.4.2 PAA+C16TAB添加鹽類系統表面張力結果討論 60 4.4.3 C16TAB添加鹽類系統電導度結果討論 64 4.5 PAA+C16TAB添加鹽類系統結果歸納 69 第五章 雙成分Pluronic水凝膠: F108+P103 76 5.1 不同濃度比例下雙成分Pluronic系統的凝膠化行為 76 5.2 F108+P103系統之動力學效應 79 5.3 晶體相的結構改變 85 5.4 F108+P103系統結果統整 90 第六章 結論 94 參考文獻 96 附錄 102 | |
| dc.language.iso | zh-TW | |
| dc.subject | 水凝膠 | zh_TW |
| dc.subject | 恆溫滴定熱卡計 | zh_TW |
| dc.subject | 混合微胞 | zh_TW |
| dc.subject | 聚電解質 | zh_TW |
| dc.subject | 界面活性劑 | zh_TW |
| dc.subject | 動態效應 | zh_TW |
| dc.subject | Kinetic effect | en |
| dc.subject | Polyelectrolyte | en |
| dc.subject | Surfactant | en |
| dc.subject | Mixed micelles | en |
| dc.subject | Isothermal titration calorimetry | en |
| dc.subject | Pluronic | en |
| dc.subject | Gel | en |
| dc.title | 帶相反電性之聚電解質/界面活性劑系統添加鹽類的效應其熱力學性質探討與雙成分共聚物高分子形成水凝膠之動態效應 | zh_TW |
| dc.title | A Study on Thermodynamic Properties of Oppositely Charged Polyelectrolyte/Surfactant system in the Presence of Salts and Dynamic Effect of Hydrogel Formation for Binary Copolymer System | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 109-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 崔宏瑋(Hung-Wei Tsui),蔡瑞瑩(Ruey-Yug Tsay),林析右(Shi-Yow Lin) | |
| dc.subject.keyword | 聚電解質,界面活性劑,混合微胞,恆溫滴定熱卡計,水凝膠,動態效應, | zh_TW |
| dc.subject.keyword | Polyelectrolyte,Surfactant,Mixed micelles,Isothermal titration calorimetry,Pluronic,Gel,Kinetic effect, | en |
| dc.relation.page | 114 | |
| dc.identifier.doi | 10.6342/NTU202100091 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2021-01-20 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 化學工程學研究所 | zh_TW |
| 顯示於系所單位： | 化學工程學系 | |
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