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標題: | 角膜基質層結構之光學特性分析以及架設Shack-Hartmann 波前量測系統並利用於量測水凝膠樣品折射率 Analysis of Optical Properties of Corneal Stroma Structure and Measuring refractive index of Hydrogel Sample by the Shack-Hartmann Wavefront Sensor System |
作者: | Jia-Hong Jian 簡嘉鋐 |
指導教授: | 李佳翰(Jia-Han Li) |
關鍵字: | 角膜基質層,時域有限差分法,澤尼克多項式,波前像差成像分析,Shack-Hartmann波前傳感器, Corneal stroma,finite-difference time-domain method,Zernike polynomials,Analysis imaging of wavefront aberration,Shack-Hartmann wavefront sensor, |
出版年 : | 2020 |
學位: | 碩士 |
摘要: | 在本論文中,為了解角膜基質層結構對角膜透光率的影響,我們採用時域有限差分法模擬了基質層膠原纖維結構的穿透率。在角膜基質層結構中,膠原蛋白纖維在基質中的排列方式、膠原蛋白纖維和其他填充材料的折射率差異以及基質層結構的堆疊方式都會影響角膜基質層的光學特性。因此,我們設置了以不同角度排列的基質層結構,並模擬了不同的結構。我們的模擬結果表明使用特定的角膜基質層堆疊結構可以得到較好的穿透率。這模擬結果對於設計人工角膜可做為一項參考。
我們也設置了Shack-Hartmann波前量測系統,以測量隱形眼鏡的光學特性以及由壓克力模具製成的水凝膠待測物的波前像差。因為難以量測水凝膠材料的折射率,故我們使用Shack-Hartmann波前量測系統量測水凝膠材料的波前像差,並利用公式推導,估算出此材料的折射率。此套系統可以幫助我們在將材料用於人造角膜之前了解材料的光學特性。 In this thesis, to understand the effects of the corneal stroma structures on the optical transmissions for the cornea, we use the finite-difference time-domain method to simulate the transmittance of the stroma collagen fiber structures. The effects of arrangement of collagen fiber in the stroma, the different refractive index between the collagen fiber and filler, and the arrangement of the stroma structure will change the transmittance of corneal stroma. Therefore, we setup the stroma structures which are arranged at different angles and simulate the different structures. Our simulation results show that the better transmittance can be achieved by using a specific stack arranging structure of corneal stroma. This finding can be useful for further design of artificial cornea. We also constructed the Shack-Hartmann wavefront sensor to measure the optical properties of the contact lenses and wavefront aberrations of hydrogel samples which were made by acrylic molds. Because it is hard to measure the refractive index of hydrogel material, we used the Shack-Hartmann wavefront measurement system to measure the wavefront aberration of the hydrogel material and used the formula to estimate the refractive index of the material. This system helps us understand the optical properties of the material before applying it to the artificial cornea. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/7374 |
DOI: | 10.6342/NTU202000381 |
全文授權: | 同意授權(全球公開) |
電子全文公開日期: | 2025-02-17 |
顯示於系所單位: | 工程科學及海洋工程學系 |
文件中的檔案:
檔案 | 大小 | 格式 | |
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ntu-109-1.pdf 此日期後於網路公開 2025-02-17 | 2.56 MB | Adobe PDF |
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