請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/73095
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 詹長權(Chang-Chuan Chan) | |
dc.contributor.author | MengTing Yu | en |
dc.contributor.author | 余孟庭 | zh_TW |
dc.date.accessioned | 2021-06-17T07:17:17Z | - |
dc.date.available | 2020-01-01 | |
dc.date.copyright | 2019-08-26 | |
dc.date.issued | 2019 | |
dc.date.submitted | 2019-07-11 | |
dc.identifier.citation | ASSESSMENT, D.-R. IPCS. Environmental Health Criteria, 214. Banerjee, D., Banerjee, H. (2012). Thiacloprid residues and its safety evaluation in Darjeeling tea. Bull Environ Contam Toxicol, 89(3), 598-601. doi:10.1007/s00128-012-0731-7 Blacquiere, T., Smagghe, G., van Gestel, C. A., Mommaerts, V. (2012). Neonicotinoids in bees: a review on concentrations, side-effects and risk assessment. Ecotoxicology, 21(4), 973-992. doi:10.1007/s10646-012-0863-x Chia-Hsin Tsai, (2017). Development of a rapid immune-detection method for residual. neonicotinoid pesticides. Retrieved from https://hdl.handle.net/11296/bj8gfv Chen, H., Wang, Q., Jiang, Y., Wang, C., Yin, P., Liu, X., Lu, C. (2015). Monitoring and risk assessment of 74 pesticide residues in Pu-erh tea produced in Yunnan, China. Food Addit Contam Part B Surveill, 8(1), 56-62. doi:10.1080/19393210.2014.972471 David, D., George, I. A., Peter, J. V. (2008). Toxicology of the newer neonicotinoid insecticides: Imidacloprid poisoning in a human. Clinical Toxicology, 45(5), 485-486. doi:10.1080/15563650701338229 Duzguner, V., Erdogan, S. (2012). Chronic exposure to imidacloprid induces inflammation and oxidative stress in the liver central nervous system of rats. Pesticide Biochemistry and Physiology, 104(1), 58-64. doi:10.1016/j.pestbp.2012.06.011 FAO. (2017a). INTERGOVERNMENTAL GROUP ON TEA. FAO. (2017b). Report of the Working Group on Maximum Residue Level. Forrester, M. B. (2014). Neonicotinoid insecticide exposures reported to six poison centers in Texas. Hum Exp Toxicol, 33(6), 568-573. doi:10.1177/0960327114522500 Gupta, M., Shanker, A. (2009). Fate of imidacloprid and acetamiprid residues during black tea manufacture and transfer into tea infusion. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 26(2), 157-163. doi:10.1080/02652030802363782 Harada, K. H., Tanaka, K., Sakamoto, H., Imanaka, M., Niisoe, T., Hitomi, T., . . . Koizumi, A. (2016). Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics. PLoS One, 11(1), e0146335. doi:10.1371/journal.pone.0146335 Hirano, T., Yanai, S., Omotehara, T., Hashimoto, R., Umemura, Y., Kubota, N., . . . Hoshi, N. (2015). The combined effect of clothianidin and environmental stress on the behavioral and reproductive function in male mice. J Vet Med Sci, 77(10), 1207-1215. doi:10.1292/jvms.15-0188 Ikenaka, Y., Fujioka, K., Kawakami, T., Ichise, T., Bortey-Sam, N., Nakayama, S. M. M., . . . Ishizuka, M. (2018). Contamination by neonicotinoid insecticides and their metabolites in Sri Lankan black tea leaves and Japanese green tea leaves. Toxicol Rep, 5, 744-749. doi:10.1016/j.toxrep.2018.06.008 Kathage, J., Castanera, P., Alonso-Prados, J. L., Gomez-Barbero, M., Rodriguez-Cerezo, E. (2018). The impact of restrictions on neonicotinoid and fipronil insecticides on pest management in maize, oilseed rape and sunflower in eight European Union regions. Pest Manag Sci, 74(1), 88-99. doi:10.1002/ps.4715 Kim, B. M., Park, J.-S., Choi, J.-H., Abd El-Aty, A. M., Na, T. W., Shim, J.-H. (2012). Residual determination of clothianidin and its metabolites in three minor crops via tandem mass spectrometry. Food Chemistry, 131(4), 1546-1551. doi:10.1016/j.foodchem.2011.09.134 Klein, S., Cabirol, A., Devaud, J. M., Barron, A. B., Lihoreau, M. (2017). Why Bees Are So Vulnerable to Environmental Stressors. Trends Ecol Evol, 32(4), 268-278. doi:10.1016/j.tree.2016.12.009 Liao, Ching-Liang(2010).Taiwan cha sheng ching. Taipei: Yang-Chin Book Co., Ltd. Publishing. Luiking, Y. C., Engelen, M. P., Deutz, N. E. (2010). Regulation of nitric oxide production in health and disease. Curr Opin Clin Nutr Metab Care, 13(1), 97-104. doi:10.1097/MCO.0b013e328332f99d Nobuhiko Hoshi, Tetsushi Hirano, Takuya Omotehara, Junko Tokumoto,a Yuria Umemura, Youhei Mantani, Takashi Tanida, Katsuhiko Warita, Yoshiaki Tabuchi, Toshifumi Yokoyama, and Hiroshi Kitagawab. (2014). Insight into the mechanism of reproductive dysfuntion caused by neonicotinoid pesticides The Pharmaceutical Society of Japan, Vol. 37, No. 9, 1439–1443. Phua, D. H., Lin, C. C., Wu, M.-L., Deng, J.-F., Yang, C.-C. (2009). Neonicotinoid insecticides: an emerging cause of acute pesticide poisoning. Clinical Toxicology, 47(4), 336-341. doi:10.1080/15563650802644533 Toor, H. K., Sangha, G. K., Khera, K. S. (2013). Imidacloprid induced histological and biochemical alterations in liver of female albino rats. Pestic Biochem Physiol, 105(1), 1-4. doi:10.1016/j.pestbp.2012.10.001 Xu Wang, A. A., Qinghua Wu,Fang Qiao, Irma Ares, María-Rosa Martínez-Larrañaga, Zonghui Yuan, and María-Aránzazu Martínez1. (2017). Mechanism of Neonicotinoid Toxicity: Impact on Oxidative Stress and Metabolism. Annual Review of Pharmacology and Toxicology, 58:471-507. doi:10.1146/annurev- | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/73095 | - |
dc.description.abstract | 茶是世界上消費量第二大的飲料。雖然日本以其綠茶而聞名,台灣也有享譽全球的茶,如烏龍茶、紅茶、和高山茶。隨著飲茶的普及,茶葉在食品安全的議題也逐漸被重視。過去的研究顯示,茶葉在食品安全的議題也逐漸被重視;飲茶的潛在風險逐漸增加。在台灣,新菸鹼類已成為茶葉種植中最重要的殺蟲劑之一。但是,我們對茶葉中的新菸鹼類農藥殘留物了解甚少。新菸鹼類是一種系統性的殺蟲劑,已知對環境有不利的影響,並導致蜜蜂不育以及土壤和水污染。利用液相層析質譜儀(LC / MS-MS)來分析台灣產量排名前十二的鄉鎮所產之茶葉,來評估新菸鹼類殘留物及其是否有代謝產物殘留的可能性。並使用日本、歐盟、和中國的最大殘留標準(MRL)與之前日本茶葉殘留的研究(n = 39)進行比較。此研究結果表明,台灣樣本檢測到的新菸鹼類頻率較低,而代謝物殘留值相近於日本茶葉樣本。雖然在台灣茶樣品中未檢出賽果培,但檢出賽果培的代謝產物N-dc-dh-thiacloprid,可能具有新菸鹼類代謝產物殘留的隱患。台灣和日本的茶葉樣品都沒有超出該國所定的最大殘留量標準,但兩國所檢出之亞滅培及益達胺殘留量皆不符合歐盟標準。此研究反映各國最大農藥殘留料標準不同,可能在茶葉進出口上有所影響,新菸鹼類代謝產物在未來的研究中也應被重視。 | zh_TW |
dc.description.abstract | Tea is the second most consumed beverage in the world. While Japan is famous for its green tea, Taiwan has many varieties, such as oolong, black tea, and mountain teas, which are also world-renowned. As the popularity of tea increases, food safety has been considered. Studies have indicated that there is a growing concern of pesticide residue in food and insecticides residue in tea. In Taiwan, neonicotinoids have become one of the most significant insecticides used in tea cultivation. Neonicotinoid is a major insecticide known to have adverse environmental effects and have contributed to infertility in bees as well as soil and water pollution. However, little is known of neonicotinoid residues in tea. The aim of this study is to evaluate the possibility of neonicotinoids and their metabolites residues remaining in tea. 12 tea samples collected from the highest tea producing townships in Taiwan were analyzed by liquid chromatography-mass spectroscopy (LC/MS-MS). The results using maximum residue level (MRL) standards from Taiwan, Japan, the European Union, and China were compared with the previous study of Japanese tea (n=39). Our findings show that Taiwanese samples have a lower frequency of neonicotinoids while the median level of metabolites is higher than that of Japanese samples. Although thiacloprid was not detected in Taiwanese tea samples, its metabolite N-descyano-dehydro-thiacloprid was expressed, suggesting a hidden risk of neonicotinoids in tea. The levels of neonicotinoids in both Taiwanese and Japanese tea samples do not exceed their domestic MRL standards, whereas the levels of acetamiprid and imidacloprid do not meet the European Union standard. This study concludes that different residue standards among countries may affect export and import of tea and that metabolites residue in tea leaves should be a concern in a further study. | en |
dc.description.provenance | Made available in DSpace on 2021-06-17T07:17:17Z (GMT). No. of bitstreams: 1 ntu-108-R06459005-1.pdf: 1955030 bytes, checksum: 0887ff232952b439c0ebd712751e394e (MD5) Previous issue date: 2019 | en |
dc.description.tableofcontents | Contents 口試委員審定書 ii 誌謝 iii Acknowledgement v 中文摘要 vii Abstract viii Contents x Comprehensive report 1 A. Introduction 1 B. Material and Method 5 C. Results 6 D. Discussion 8 E. Conclusion 15 F. Content of Implementation 16 G. General Consideration and Outlook 16 H. Limitations 21 Reference 22 Appendix-1 Neonicotinoids banned regulation from European Union- imidacloprid 39 Appendix-2 Neonicotinoids banned regulation from European Union- clothianidin 49 Appendix-3 Neonicotinoids banned regulation from European Union- thiamethoxam 61 Figures Figure 1. Classification of neonicotinoids (Taiwan Agricultural Chemicals and Toxic Substances Research Institute, 2018) 25 Figure 2. Five main tea production areas (in orange) in Taiwan 26 Figure 3. Five main tea production prefectures in Japan 27 Figure 4. The analysis of method. 28 Figure 5. Compare each neonicotinoid with Japan and Taiwan tea residue and MRLs of Japan, Taiwan, European Union (EU), and China. Japan source from The Ministry of Agriculture, Forestry and Fisheries of Japan (MAFF), 2017. 29 Figure 6. The country acts on neonicotinoids in the world. 30 Figure 7. The risk assessment of neonicotinoids residue. 31 Figure 8. The scheme of idea for technology application. 32 Tables Table 1. The list of Taiwan tea samples 33 Table 2. LOD and LOQ data of target neonicotinoids and related metabolites 34 Table 3. Compare concentrations (ng/g ww) and the % frequencies of detection of neonicotinoids in tea leaves from Taiwan and Japan 35 Table 4 Comparison of Neonicotinoids metabolites detection in Japan and Taiwan tea leaves 36 Table 5. The MRLs (mg/kg) of neonicotinoids pesticide in tea 37 Table 6. Major courses that help with research. 38 | |
dc.language.iso | en | |
dc.title | 新菸鹼類農藥在台灣與日本茶葉中殘留之比較 | zh_TW |
dc.title | Comparisons of neonicotinoids residue in tea leaves from Taiwan and Japan | en |
dc.type | Thesis | |
dc.date.schoolyear | 107-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 姜至剛(Chih-Kang Chiang),蕭寧馨(Ning-Sing Shaw),王淑珍(Shu-Jen, Wang) | |
dc.subject.keyword | 茶,新菸鹼類農藥, | zh_TW |
dc.subject.keyword | Tea,Neonicotinoids, | en |
dc.relation.page | 71 | |
dc.identifier.doi | 10.6342/NTU201901342 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2019-07-12 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 國際三校農業生技與健康醫療碩士學位學程 | zh_TW |
顯示於系所單位: | 國際三校農業生技與健康醫療碩士學位學程 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-108-1.pdf 目前未授權公開取用 | 1.91 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。