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DC 欄位值語言
dc.contributor.advisor吳恩賜(Oon-Soo Goh)
dc.contributor.authorChe-Yu Chouen
dc.contributor.author周哲宇zh_TW
dc.date.accessioned2021-06-17T06:05:21Z-
dc.date.available2020-03-05
dc.date.copyright2019-03-05
dc.date.issued2019
dc.date.submitted2019-01-18
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dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/71642-
dc.description.abstractGreater prosocial behavior in older than younger adults, such as in financial donations, has been suggested to stem from increased empathy with age. We considered, however, that young and older prosocial decisions might also reflect motivations apart from empathy such as other more self-oriented reasons. In this present study, young and older adults underwent an fMRI experiment in which they apportioned real money to others during decision phases of hypothetical scenarios. Scenarios included opportunities to be prosocial, make typical purchases, or were neutral scenarios not typically requiring exchange of money. Participants’ decided amounts were then selectively adjusted in feedback on scenario outcomes and self-report on emotional reactions assessed. As expected, older adults apportioned more money than younger adults in prosocial scenarios. However, young adults reported greater magnitudes of emotional reactions than older adults. Age modulated scenario decision neural processing with a ventral to dorsal in the medial prefrontal cortex. These regions evinced lower neural activity to prosocial than purchase or neutral scenarios in older than younger adults, whereas younger adults were reversed. Critically, lower VMPFC activity was associated with more prosocial money apportioned and greater personal distress scores more in older adults, but with greater empathy concern more in younger adults. These findings suggest that young adults may not be less empathetic than older adults during financial prosocial decision. Moreover, other motivational psychological mechanisms might underlie older adult prosocial behaviors apart from general empathy.en
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dc.description.tableofcontentsAcknowledgement I
中文摘要 II
Abstract III
Introduction 1
● Difficulties in associating age-related greater prosocial behavior with greater empathy 1
● Prosocial processing engages differential brain areas in young and older adults 5
● Differential self- and other-oriented motivations account for prosocial behavior and medial prefrontal processing in young and older adult 6
Methods 8
● Participant 8
● Stimuli and materials 8
● Procedure 11
● Behavioral Analysis 12
● Image acquisition 13
● fMRI Data processing and Analysis 14
Result 18
● Older adults appropriate more money than younger adults in prosocial scenarios 18
● Higher amounts of money appropriated associated with personal distress in old but with greater empathy and higher financial income in young 18
● Higher frontal neural responses to prosocial choices in younger than older adults 19
● Lower neural responses in regions of interest associated with greater personal distress and greater prosocial money appropriated in older adults 19
● Younger adults showed greater reward response during -NT50 PUR than -NT$50 PRO in ER phase 20
● Visual regions modulated emotion reaction in both young and old 21
Discussion 22
References 30
Figures
Figure 1. Example trial of monetary appropriation task (MAT) 42
Figure 2. Bar plots of mean amounts of money appropriated during MD phase for young and older adults 43
Figure 3. Scatterplots of correlation between corrected prosocial MMA and questionnaires 44
Figure 4. Whole brain activation during age interacted with scenario 45
Figure 5. Scatterplots of correlation between neural responses in region-a, region-b, and corrected prosocial MMA, and IRI-PD scores 46
Figure 6. Mean emotion reactions and brain activity during the ER phase 47
Supplementary Figures and Table
Figure 1. Scatter plots of relations between emotion reaction and monetary adjustment distance 48
Figure 2. Brain regions sensitive to the change of money regulation manipulated by parametric contrasts 49
Table 1. Detail situations of the four scenarios in the monetary appropriation task (MAT) 50
Table 2. ANOVA table of MD scenarios and age group 53
Table 3. Post-hoc group t-test by scenarios for MD phase 54
Table 4. Summary of questionnaires score of young and old participants 55
Table 5. Regression models of within group behavioral money appropriated interaction parameter estimates with age and questionnaires 56
Table 6. ANOVA table of ROIs interacted with age groups and scenarios 57
Table 7. Brain activation table of age and scenario interaction during MD phas 58
Table 8. ANOVA table of age and MD phase ROI estimate interaction 59
Table 9. Post-hoc group t-test by scenarios for MD ROI estimate values 60
Table 10. ANOVA table of age and ER phase monetary adjustment levels interaction during PRO and PUR scenarios 61
Table 11. Categorical post-hoc t-test of age difference in ER phase during PRO and PUR scenario 62
Table 12. Brain activation table during ER phase 63
Table 13. Mediation analysis table between signal parameter estimate and the amount of money appropriated using IRI-PD score as mediator in ROI region-a (ROI-a) and region-b (ROI-b) 65
dc.language.isoen
dc.title前額葉皮質參與親社會行為中「自我」與「他人」相關之處理的年齡差異zh_TW
dc.titleDifferential medial prefrontal engagement associated with
self- and other-processing during older and younger adult prosocial behaviors
en
dc.typeThesis
dc.date.schoolyear107-1
dc.description.degree碩士
dc.contributor.oralexamcommittee吳建德(Chien-Te Wu),張玉玲(Yu-Ling Chang)
dc.subject.keyword老化,認知功能,親社會行為,同理心,功能性磁振造影,zh_TW
dc.subject.keywordAging,cognitive function,prosocial behavior,empathy,fMRI,en
dc.relation.page65
dc.identifier.doi10.6342/NTU201804353
dc.rights.note有償授權
dc.date.accepted2019-01-21
dc.contributor.author-college醫學院zh_TW
dc.contributor.author-dept腦與心智科學研究所zh_TW
顯示於系所單位:腦與心智科學研究所

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