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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 郭鐘金(Chung-Chin Kuo) | |
dc.contributor.author | Yin-Chieh Chen | en |
dc.contributor.author | 陳映潔 | zh_TW |
dc.date.accessioned | 2021-06-17T06:01:14Z | - |
dc.date.available | 2022-03-05 | |
dc.date.copyright | 2019-03-05 | |
dc.date.issued | 2019 | |
dc.date.submitted | 2019-02-11 | |
dc.identifier.citation | Adermark, L., R. B. Clarke, M. Ericson and B. Soderpalm (2011). 'Subregion-Specific Modulation of Excitatory Input and Dopaminergic Output in the Striatum by Tonically Activated Glycine and GABA(A) Receptors.' Front Syst Neurosci 5: 85.
Albin, R. L., Young, A. B., & Penney, J. B. (1989). The functional anatomy of basal ganglia disorders. Trends in neurosciences, 12(10), 366-375. Alexander, G. E., & Crutcher, M. D. (1990). Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends in neurosciences, 13(7), 266-271. Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual review of neuroscience, 9(1), 357-381. Angulo, M. C., Rossier, J., & Audinat, E. (1999). Postsynaptic glutamate receptors and integrative properties of fast-spiking interneurons in the rat neocortex. Journal of Neurophysiology, 82(3), 1295-1302. Ariano, M. A., Wang, J., Noblett, K. L., Larson, E. R., & Sibley, D. R. (1997). Cellular distribution of the rat D4 dopamine receptor protein in the CNS using anti-receptor antisera. Brain research, 752(1-2), 26-34. Ashby, F. G., Turner, B. O., & Horvitz, J. C. (2010). Cortical and basal ganglia contributions to habit learning and automaticity. Trends in cognitive sciences, 14(5), 208-215. Atherton, J. F., Menard, A., Urbain, N., & Bevan, M. D. (2013). Short-term depression of external globus pallidus-subthalamic nucleus synaptic transmission and implications for patterning subthalamic activity. Journal of Neuroscience, 33(17), 7130-7144. Báez-Mendoza, R., & Schultz, W. (2013). The role of the striatum in social behavior. Frontiers in neuroscience, 7, 233. Barroso-Flores, J., Herrera-Valdez, M. A., Galarraga, E., & Bargas, J. (2017). Models of Short-Term Synaptic Plasticity. In The Plastic Brain (pp. 41-57). Springer, Cham. Benarroch, E. E. (2012). Effects of acetylcholine in the striatum: recent insights and therapeutic implications. Neurology, 79(3), 274-281. Benhamou, L., Bronfeld, M., Bar-Gad, I., & Cohen, D. (2012). Globus Pallidus external segment neuron classification in freely moving rats: a comparison to primates. PloS one, 7(9), e45421. Banke, T. G., Bowie, D. L. H. K., Lee, H. K., Huganir, R. L., Schousboe, A., & Traynelis, S. F. (2000). Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. Journal of Neuroscience, 20(1), 89-102. Bergman, H., Wichmann, T., Karmon, B., & DeLong, M. R. (1994). The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. Journal of neurophysiology, 72(2), 507-520. Bergstrom, D. A., & Walters, J. R. (1984). Dopamine attenuates the effects of GABA on single unit activity in the globus pallidus. Brain research, 310(1), 23-33. Beurrier, C., Congar, P., Bioulac, B., & Hammond, C. (1999). Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode. Journal of Neuroscience, 19(2), 599-609. Beurrier, C., Bioulac, B., & Hammond, C. (2000). Slowly inactivating sodium current (I NaP) underlies single-spike activity in rat subthalamic neurons. Journal of Neurophysiology, 83(4), 1951-1957. Bevan, M. D., & Wilson, C. J. (1999). Mechanisms underlying spontaneous oscillation and rhythmic firing in rat subthalamic neurons. Journal of Neuroscience, 19(17), 7617-7628. Bevan, M. D., Magill, P. J., Terman, D., Bolam, J. P., & Wilson, C. J. (2002). Move to the rhythm: oscillations in the subthalamic nucleus–external globus pallidus network. Trends in neurosciences, 25(10), 525-531. Blitz, D. M., Foster, K. A., & Regehr, W. G. (2004). Short-term synaptic plasticity: a comparison of two synapses. Nature Reviews Neuroscience, 5(8), 630. Bodden, M. E., Dodel, R., & Kalbe, E. (2010). Theory of mind in Parkinson's disease and related basal ganglia disorders: a systematic review. Movement Disorders, 25(1), 13-27. Bohnen, N. I., & Albin, R. L. (2011). The cholinergic system and Parkinson disease. Behavioural brain research, 221(2), 564-573. Bonsi, P., Cuomo, D., Martella, G., Madeo, G., Schirinzi, T., Puglisi, F., ... & Pisani, A. (2011). Centrality of striatal cholinergic transmission in basal ganglia function. Frontiers in neuroanatomy, 5, 6. Borovikova, L. V., S. Ivanova, M. Zhang, H. Yang, G. I. Botchkina, L. R. Watkins, H. Wang, N. Abumrad, J. W. Eaton and K. J. Tracey (2000). 'Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin.' Nature 405(6785): 458-462. Brittain, J. S., Sharott, A., & Brown, P. (2014). The highs and lows of beta activity in cortico‐basal ganglia loops. European Journal of Neuroscience, 39(11), 1951-1959. Calabresi, P., Picconi, B., Tozzi, A., Ghiglieri, V., & Di Filippo, M. (2014). Direct and indirect pathways of basal ganglia: a critical reappraisal. Nature neuroscience, 17(8), 1022. Cho, J. H., & Askwith, C. C. (2008). Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice. Journal of neurophysiology, 99(2), 426-441. Choi, S., & Lovinger, D. M. (1997). Decreased frequency but not amplitude of quantal synaptic responses associated with expression of corticostriatal long-term depression. Journal of Neuroscience, 17(21), 8613-8620. Coddou, C., Bravo, E., & Eugenín, J. (2009). Alterations in cholinergic sensitivity of respiratory neurons induced by pre-natal nicotine: a mechanism for respiratory dysfunction in neonatal mice. Philosophical Transactions of the Royal Society of London B: Biological Sciences, 364(1529), 2527-2535. Cooper, A. J., & Stanford, I. M. (2000). Electrophysiological and morphological characteristics of three subtypes of rat globus pallidus neurone in vitro. The Journal of Physiology, 527(2), 291-304. Cooper, A. J., & Stanford, I. M. (2001). Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABAA IPSCs in vitro. Neuropharmacology, 41(1), 62-71. Cui, G., Jun, S. B., Jin, X., Pham, M. D., Vogel, S. S., Lovinger, D. M., & Costa, R. M. (2013). Concurrent activation of striatal direct and indirect pathways during action initiation. Nature, 494(7436), 238. Deffains, M., & Bergman, H. (2015). Striatal cholinergic interneurons and cortico‐striatal synaptic plasticity in health and disease. Movement Disorders, 30(8), 1014-1025. Deffains, M., Iskhakova, L., & Bergman, H. (2016). Stop and think about basal ganglia functional organization: the pallido-striatal “stop” route. Neuron, 89(2), 237-239. Del Castillo J, Katz B (1954) Quantal components of the end-plate potential. J Physiol (Lond) 124:560–573. DeLong, M. R. (1990). Primate models of movement disorders of basal ganglia origin. Trends in neurosciences, 13(7), 281-285. DeLong, M. R., & Wichmann, T. (2007). Circuits and circuit disorders of the basal ganglia. Archives of neurology, 64(1), 20-24. DeLong, M. R., & Wichmann, T. (2015). Basal ganglia circuits as targets for neuromodulation in Parkinson disease. JAMA neurology, 72(11), 1354-1360. Deniau, J. M., Mailly, P., Maurice, N., & Charpier, S. (2007). The pars reticulata of the substantia nigra: a window to basal ganglia output. Progress in brain research, 160, 151-172. Duda, J., Pötschke, C., & Liss, B. (2016). Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's disease. Journal of neurochemistry, 139, 156-178. Fioravante, D., & Regehr, W. G. (2011). Short-term forms of presynaptic plasticity. Current opinion in neurobiology, 21(2), 269-274. Floran, B., Floran, L., Sierra, A., & Aceves, J. (1997). D2 receptor-mediated inhibition of GABA release by endogenous dopamine in the rat globus pallidus. Neuroscience letters, 237(1), 1-4. Flores, G., Hernandez, S., Rosales, M. G., Sierra, A., Martines-Fong, D., Flores-Hernandez, J., & Aceves, J. (1996). M3 muscarinic receptors mediate cholinergic excitation of the spontaneous activity of subthalamic neurons in the rat. Neuroscience letters, 203(3), 203-206. Flores‐Hernandez, J., Salgado, H., De la Rosa, V., Avila‐Ruiz, T., Torres‐Ramirez, O., Lopez‐Lopez, G., & Atzori, M. (2009). Cholinergic direct inhibition of N‐methyl‐D aspartate receptor‐mediated currents in the rat neocortex. Synapse, 63(4), 308-318. Foerde, K., & Shohamy, D. (2011). The role of the basal ganglia in learning and memory: insight from Parkinson’s disease. Neurobiology of learning and memory, 96(4), 624-636. Forsythe, I. D., Tsujimoto, T., Barnes-Davies, M., Cuttle, M. F., & Takahashi, T. (1998). Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse. Neuron, 20(4), 797-807. Gerfen, C. R., Engber, T. M., Mahan, L. C., Susel, Z. V. I., Chase, T. N., Monsma, F. J., & Sibley, D. R. (1990). D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science, 250(4986), 1429-1432. German, D. C., & Manaye, K. F. (1993). Midbrain dopaminergic neurons (nuclei A8, A9, and A10): three‐dimensional reconstruction in the rat. Journal of Comparative Neurology, 331(3), 297-309. Giocomo, L. M. and M. E. Hasselmo (2005). 'Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus.' Eur J Neurosci 22(6): 1349-1356. Gittis, A. H., Berke, J. D., Bevan, M. D., Chan, C. S., Mallet, N., Morrow, M. M., & Schmidt, R. (2014). New roles for the external globus pallidus in basal ganglia circuits and behavior. Journal of Neuroscience, 34(46), 15178-15183. Guo, J.-Z., T. L. Tredway and V. A. Chiappinelli (1998). 'Glutamate and GABA Release Are Enhanced by Different Subtypes of Presynaptic Nicotinic Receptors in the Lateral Geniculate Nucleus.' The Journal of Neuroscience 18(6): 1963-1969. Haber, S. N. (2016). Corticostriatal circuitry. Neuroscience in the 21st Century, 1-21. Hadipour Niktarash, A., Lee, H., Khan, Z. U., Smith, Y., and Wichmann, T. (2008). Effects of D2-like dopamine receptor activation on neuronal activ¬ity in substantia nigra pars reticulata and globus pallidus in monkeys. Soc. Neurosci. Abstr. 274.271. Hamani, C., Saint‐Cyr, J. A., Fraser, J., Kaplitt, M., & Lozano, A. M. (2004). The subthalamic nucleus in the context of movement disorders. Brain, 127(1), 4-20. Han, E. B., & Stevens, C. F. (2009). Development regulates a switch between post-and presynaptic strengthening in response to activity deprivation. Proceedings of the National Academy of Sciences, 106(26), 10817-10822. Hartmann-von Monakow, K., Akert, K., & Künzle, H. (1978). Projections of the precentral motor cortex and other cortical areas of the frontal lobe to the subthalamic nucleus in the monkey. Experimental brain research, 33(3-4), 395-403. Haas, H. L. and O. Selbach (2000). 'Functions of neuronal adenosine receptors.' Naunyn-Schmiedeberg's Archives of Pharmacology 362(4-5): 375-381. Hegeman, D. J., Hong, E. S., Hernández, V. M., & Chan, C. S. (2016). The external globus pallidus: progress and perspectives. European Journal of Neuroscience, 43(10), 1239-1265. Hernández, A., Ibáñez-Sandoval, O., Sierra, A., Valdiosera, R., Tapia, D., Anaya, V., ... & Aceves, J. (2006). Control of the subthalamic innervation of the rat globus pallidus by D2/3 and D4 dopamine receptors. Journal of neurophysiology, 96(6), 2877-2888. Hernández, A., Sierra, A., Valdiosera, R., Florán, B., Erlij, D., & Aceves, J. (2007). Presynaptic D1 dopamine receptors facilitate glutamatergic neurotransmission in the rat globus pallidus. Neuroscience letters, 425(3), 188-191. Hong, S., & Hikosaka, O. (2008). The globus pallidus sends reward-related signals to the lateral habenula. Neuron, 60(4), 720-729. Hormuzdi, S. G., I. Pais, F. E. N. LeBeau, S. K. Towers, A. Rozov, E. H. Buhl, M. A. Whittington and H. Monyer (2001). 'Impaired Electrical Signaling Disrupts Gamma Frequency Oscillations in Connexin 36-Deficient Mice.' Neuron 31(3): 487-495. Huang, L., Deng, M., He, Y., Lu, S., Ma, R., & Fang, Y. (2016). β‐asarone and levodopa co‐administration increase striatal dopamine level in 6‐hydroxydopamine induced rats by modulating P‐glycoprotein and tight junction proteins at the blood‐brain barrier and promoting levodopa into the brain. Clinical and Experimental Pharmacology and Physiology, 43(6), 634-643. Ibanez-Sandoval, O., Hernández, A., Florán, B., Galarraga, E., Tapia, D., Valdiosera, R., ... & Bargas, J. (2006). Control of the subthalamic innervation of substantia nigra pars reticulata by D1 and D2 dopamine receptors. Journal of neurophysiology, 95(3), 1800-1811. Jin, X., Tecuapetla, F., & Costa, R. M. (2014). Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences. Nature neuroscience, 17(3), 423. Johnson, K. A., Conn, P. J., & Niswender, C. M. (2009). Glutamate receptors as therapeutic targets for Parkinson's disease. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 8(6), 475-491. Jones, S., S. Sudweeks and J. L. Yakel (1999). 'Nicotinic receptors in the brain: correlating physiology with function.' Trends in Neurosciences 22(12):555-561. Katz, B., & Miledi, R. (1968). The role of calcium in neuromuscular facilitation. The Journal of physiology, 195(2), 481-492. Kawaguchi, Y., Wilson, C. J., & Emson, P. C. (1990). Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin. Journal of Neuroscience, 10(10), 3421-3438. Kayadjanian, N., Menétrey, A., & Besson, M. J. (1997). Activation of muscarinic receptors stimulates GABA release in the rat globus pallidus. Synapse, 26(2), 131-139. Kejian, C., H. J. Waller and D. A. Godfrey (1994). 'Cholinergic modulation of spontaneous activity in rat dorsal cochlear nucleus.' Hearing Res. 77(1–2): 168-176. Kiagiadaki, F., E. Koulakis and K. Thermos (2008). 'Dopamine (D1) receptor activation and nitrinergic agents influence somatostatin levels in rat retina.' Exp. Eye Res. 86(1): 18-24. Kirischuk, S., Clements, J. D., & Grantyn, R. (2002). Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures. The Journal of physiology, 543(1), 99-116. Kita, H., K. Oda and K. Murase (1999). 'Effects of dopamine agonists and antagonists on optical responses evoked in rat frontal cortex slices after stimulation of the subcortical white matter.' Exp Brain Res 125(3): 383-388. Kita, H. (2007). Globus pallidus external segment. Progress in brain research, 160, 111-133. Kita, H., Nambu, A., Kaneda, K., Tachibana, Y., & Takada, M. (2004). Role of ionotropic glutamatergic and GABAergic inputs on the firing activity of neurons in the external pallidum in awake monkeys. Journal of neurophysiology, 92(5), 3069-3084. Kitai, S. T., & Deniau, J. M. (1981). Cortical inputs to the subthalamus: intracellular analysis. Brain research, 214(2), 411-415. Kleppe, I. C., & Robinson, H. P. (1999). Determining the activation time course of synaptic AMPA receptors from openings of colocalized NMDA receptors. Biophysical journal, 77(3), 1418-1427. Kline, D. D., Takacs, K. N., Ficker, E., & Kunze, D. L. (2002). Dopamine modulates synaptic transmission in the nucleus of the solitary tract. Journal of Neurophysiology, 88(5), 2736-2744. Koga, E., & Momiyama, T. (2000). Presynaptic dopamine D2‐like receptors inhibit excitatory transmission onto rat ventral tegmental dopaminergic neurones. The Journal of physiology, 523(1), 163-173. Korte, M., P. Carroll, E. Wolf, G. Brem, H. Thoenen and T. Bonhoeffer (1995). 'Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.' Proceedings of the National Academy of Sciences 92(19) : 8856-8860. Kreitzer, A. C., & Malenka, R. C. (2008). Striatal plasticity and basal ganglia circuit function. Neuron, 60(4), 543-554. Lanciego, J. L., Luquin, N., & Obeso, J. A. (2012). Functional neuroanatomy of the basal ganglia. Cold Spring Harbor perspectives in medicine, a009621. Léna, C., J. P. Changeux and C. Mulle (1993). 'Evidence for 'preterminal' nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus.' J Neurosci 13(6): 2680-2688. Ligot, N., Krystkowiak, P., Simonin, C., Goldman, S., Peigneux, P., Van Naemen, J., ... & Delmaire, C. (2011). External globus pallidus stimulation modulates brain connectivity in Huntington's disease. Journal of Cerebral Blood Flow & Metabolism, 31(1), 41-46. Lim, S. A. O., Kang, U. J., & McGehee, D. S. (2014). Striatal cholinergic interneuron regulation and circuit effects. Frontiers in synaptic neuroscience, 6, 22. Lindvall, O., & Björklund, A. (1979). Dopaminergic innervation of the globus pallidus by collaterals from the nigrostriatal pathway. Brain research, 172(1), 169-173. Mallet, N., Micklem, B. R., Henny, P., Brown, M. T., Williams, C., Bolam, J. P., ... & Magill, P. J. (2012). Dichotomous organization of the external globus pallidus. Neuron, 74(6), 1075-1086. Mamad, O., Delaville, C., Benjelloun, W., & Benazzouz, A. (2015). Dopaminergic control of the globus pallidus through activation of D2 receptors and its impact on the electrical activity of subthalamic nucleus and substantia nigra reticulata neurons. PloS one, 10(3), e0119152. Manita, S., Suzuki, T., Inoue, M., Kudo, Y., & Miyakawa, H. (2007). Paired-pulse ratio of synaptically induced transporter currents at hippocampal CA1 synapses is not related to release probability. Brain research, 1154, 71-79. Mastro, K. J., Bouchard, R. S., Holt, H. A., & Gittis, A. H. (2014). Transgenic mouse lines subdivide distinct neuronal populations in the external segment of the globus pallidus. J Neurosci, 34, 2087-2099. Mauger, C., Sivan, B., Brockhaus, M., Fuchs, S., Civelli, O., & Monsma Jr, F. (1998). Development and characterization of antibodies directed against the mouse D4 dopamine receptor. European Journal of Neuroscience, 10(2), 529-537. Mesulam, M. M., Mash, D., Hersh, L., Bothwell, M., & Geula, C. (1992). Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. Journal of Comparative Neurology, 323(2), 252-268. Mikroulis, A. V., & Psarropoulou, C. (2012). Endogenous ACh effects on NMDA‐induced interictal‐like discharges along the septotemporal hippocampal axis of adult rats and their modulation by an early life generalized seizure. Epilepsia, 53(5), 879-887. Mori, F., Okada, K. I., Nomura, T., & Kobayashi, Y. (2016). The pedunculopontine tegmental nucleus as a motor and cognitive interface between the cerebellum and basal ganglia. Frontiers in neuroanatomy, 10, 109. Mrzljak, L., Bergson, C., Pappy, M., Huff, R., Levenson, R., & Goldman-Rakic, P. S. (1996). Localization of dopamine D4 receptors in GABAergic neurons of the primate brain. Nature, 381(6579), 245. Nagel, S. J., A. G. Machado, J. T. Gale, D. A. Lobel and M. Pandya (2015). 'Preserving cortico-striatal function: deep brain stimulation in Huntington's disease.' Front Syst Neurosci 9: 32. Nambu, A., & Llinas, R. (1994). Electrophysiology of globus pallidus neurons in vitro. Journal of neurophysiology, 72(3), 1127-1139. Nambu, A., Tokuno, H., & Takada, M. (2002). Functional significance of the cortico–subthalamo–pallidal ‘hyperdirect’pathway. Neuroscience research, 43(2), 111-117. Nambu, A. (2007). Globus pallidus internal segment. Progress in brain research, 160, 135-150. Nambu, A., & Tachibana, Y. (2014). Mechanism of parkinsonian neuronal oscillations in the primate basal ganglia: some considerations based on our recent work. Fro-ntiers in systems neuroscience, 8, 74 Nambu, A., Tachibana, Y., & Chiken, S. (2015). Cause of parkinsonian symptoms: firing rate, firing pattern or dynamic activity changes?. Basal Ganglia, 5(1), 1-6. Nelson, A. B., & Kreitzer, A. C. (2014). Reassessing models of basal ganglia function and dysfunction. Annual review of neuroscience, 37, 117-135. Ni, Z. G., Bouali-Benazzouz, R., Gao, D. M., Benabid, A. L., & Benazzouz, A. (2001). Time-course of changes in firing rates and firing patterns of subthalamic nucleus neuronal activity after 6-OHDA-induced dopamine depletion in rats. Brain research, 899(1-2), 142-147. Parent, A., Sato, F., Wu, Y., Gauthier, J., Lévesque, M., & Parent, M. (2000). Organization of the basal ganglia: the importance of axonal collateralization. Trends in neurosciences, 23, S20-S27. Pavlides, A., Hogan, S. J., & Bogacz, R. (2015). Computational models describing possible mechanisms for generation of excessive beta oscillations in Parkinson’s disease. PLoS computational biology, 11(12), e1004609. Perez‐Costas, E., Melendez‐Ferro, M., & Roberts, R. C. (2010). Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of neurochemistry, 113(2), 287-302. Pickel, V. M., E. E. Colago, I. Mania, A. I. Molosh and D. G. Rainnie (2006). 'Dopamine D1 receptors co-distribute with N-methyl-D-aspartic acid type-1 subunits and modulate synaptically-evoked N-methyl-D-aspartic acid currents in rat basolateral amygdala.' Neuroscience 142(3): 671-690. Pidoplichko, V. I., M. DeBiasi, J. T. Williams and J. A. Dani (1997). 'Nicotine activates and desensitizes midbrain dopamine neurons.' Nature 390(6658): 401-404. Plenz, D., & Kital, S. T. (1999). A basal ganglia pacemaker formed by the subthalamic nucleus and external globus pallidus. Nature, 400(6745), 677. Plenz, D. (2003). When inhibition goes incognito: feedback interaction between spiny projection neurons in striatal function. Trends in neurosciences, 26(8), 436-443. Querejeta, E., Alatorre, A., Ríos, A., Barrientos, R., Oviedo-Chávez, A., Bobadilla-Lugo, R. A., & Delgado, A. (2012). Striatal input-and rate-dependent effects of muscarinic receptors on pallidal firing. The Scientific World Journal, 2012. Raymond, L. A., André, V. M., Cepeda, C., Gladding, C. M., Milnerwood, A. J., & Levine, M. S. (2011). Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. Neuroscience, 198, 252-273. Redman S (1990) Quantal analysis of synaptic potentials in neurons of the central nervous system. Rice, M. E., Patel, J. C., & Cragg, S. J. (2011). Dopamine release in the basal ganglia. Neuroscience, 198, 112-137. Ríos, A., Barrientos, R., Alatorre, A., Delgado, A., Perez-Capistran, T., Chuc-Meza, E., ... & Querejeta, E. (2016). Dopamine-dependent modulation of rat globus pallidus excitation by nicotine acetylcholine receptors. Experimental brain research, 234(2), 605-616. Rommelfanger, K. S., & Wichmann, T. (2010). Extrastriatal dopaminergic circuits of the basal ganglia. Frontiers in neuroanatomy, 4, 139. Rosales, M. G., Flores, G., Hernández, S., Martínez-Fong, D., & Aceves, J. (1994). Activation of subthalamic neurons produces NMDA receptor-mediated dendritic dopamine release in substantia nigra pars reticulata: a microdialysis study in the rat. Brain research, 645(1-2), 335-337. Rossi, M. A., Fan, D., Barter, J. W., & Yin, H. H. (2013). Bidirectional modulation of substantia nigra activity by motivational state. PLoS One, 8(8), e71598. Rubin, J. E., McIntyre, C. C., Turner, R. S., & Wichmann, T. (2012). Basal ganglia activity patterns in parkinsonism and computational modeling of their downstream effects. European Journal of Neuroscience, 36(2), 2213-2228. Sacaan, A. I., J. L. Dunlop and G. K. Lloyd (1995). 'Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices.' J. Pharmacol. Exp. Ther. 274(1): 224-230. Scanziani, M., Capogna, M., Gähwiler, B. H., & Thompson, S. M. (1992). Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus. Neuron, 9(5), 919-927. Schapira, A. H., Olanow, C. W., Greenamyre, J. T., & Bezard, E. (2014). Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives. The Lancet, 384(9942), 545-555. Schmidt, R., Leventhal, D. K., Mallet, N., Chen, F., & Berke, J. D. (2013). Canceling actions involves a race between basal ganglia pathways. Nature neuroscience, 16(8), 1118. Shen, K. Z., & Johnson, S. W. (2000). Presynaptic dopamine D2 and muscarine M3 receptors inhibit excitatory and inhibitory transmission to rat subthalamic neurones in vitro. The Journal of physiology, 525(2), 331-341. Shen, K. Z. and S. W. Johnson (2008). '5-Hydroxytryptamine inhibits synaptic transmission in rat subthalamic nucleus neurons in vitro.' Neuroscience 151(4):1029-1033. Sheridan, R. D., & Sutor, B. (1990). Presynaptic M1 muscarinic cholinoceptors mediate inhibition of excitatory synaptic transmission in the hippocampus in vitro. Neuroscience letters, 108(3), 273-278. Shin, R. M., Masuda, M., Miura, M., Sano, H., Shirasawa, T., Song, W. J., ... & Aosaki, T. (2003). Dopamine D4 receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus pallidus neurons. Journal of Neuroscience, 23(37), 11662-11672. Smith, Y., & Parent, A. (1988). Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity. Brain research, 453(1-2), 353-356. Smith, Y., Bevan, M. D., Shink, E., & Bolam, J. P. (1998). Microcircuitry of the direct and indirect pathways of the basal ganglia. Neuroscience, 86(2), 353-387. Song, W. J., Baba, Y., Otsuka, T., & Murakami, F. (2000). Characterization of Ca2+ channels in rat subthalamic nucleus neurons. Journal of Neurophysiology, 84(5), 2630-2637. Soll, L. G., Grady, S. R., Salminen, O., Marks, M. J., & Tapper, A. R. (2013). A role for α4 (non-α6) nicotinic acetylcholin rereceptors in motor behavior. Neuropharma-cology, 73, 19-30 Spruston, N., Jonas, P., & Sakmann, B. (1995). Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons. The Journal of physiology, 482(2), 325-352. Sun, Y., H. J. Waller, D. A. Godfrey and A. M. Rubin (2002). 'Spontaneous activity in rat vestibular nuclei in brain slices and effects of acetylcholine agonists and antagonists.' Brain Res. 934(1): 58-68. Surmeier, D. J., Song, W. J., & Yan, Z. (1996). Coordinated expression of dopamine receptors in neostriatal medium spiny neurons. Journal of neuroscience, 16(20), 6579-6591. Surmeier, D. J., Ding, J., Day, M., Wang, Z., & Shen, W. (2007). D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons. Trends in neurosciences, 30(5), 228-235. Starr, E. R., Imbery, J. F., & Collins, S. A. (2015). Subthalamic Nucleus Cell-Specific Expression of Nicotinic Acetylcholine Receptors Uncovers Novel Basal Ganglia Microcircuits. Journal of Neuroscience, 35(30), 10645-10646. Stevens CF (1993) Quantal release of neurotransmitter and long-term potentiation. Cell 72:55–63. Stouffer, M. A., Ali, S., Reith, M. E., Patel, J. C., Sarti, F., Carr, K. D., & Rice, M. E. (2011). SKF‐83566, a D1‐dopamine receptor antagonist, inhibits the dopamine transporter. Journal of neurochemistry, 118(5), 714-720. Thongsaard, W., S. Pongsakorn, R. Sudsuang, G. W. Bennett, D. A. Kendall and C. A. Marsden (1997). 'Barakol, a natural anxiolytic, inhibits striatal dopamine release but not uptake in vitro.' Eur. J. Pharmacol. 319(2–3): 157-164. Tsien, J. Z., P. T. Huerta and S. Tonegawa (1996). 'The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory.' Cell 87(7): 1327-1338. Waldeck, R. F., Pereda, A., & Faber, D. S. (2000). Properties and plasticity of paired-pulse depression at a central synapse. Journal of Neuroscience, 20(14), 5312-5320. Waldvogel, H. J., Kim, E. H., Tippett, L. J., Vonsattel, J. P. G., & Faull, R. L. (2014). The neuropathology of Huntington’s disease. In Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease (pp. 33-80). Springer, Berlin, Heidelberg. Wickens, J. R., Alexander, M. E., & Miller, R. (1991). Two dynamic modes of striatal function under dopaminergic‐cholinergic control: Simulation and analysis of a model. Synapse, 8(1), 1-12. Wu, M., M. Shanabrough, C. Leranth and M. Alreja (2000). 'Cholinergic Excitation of Septohippocampal GABA But Not Cholinergic Neurons: Implications for Learning and Memory.' The Journal of Neuroscience 20(10): 3900-3908. Xiang, Z., Thompson, A. D., Jones, C. K., Lindsley, C. W., & Conn, P. J. (2012). Roles of the M1 muscarinic acetylcholine receptor subtype in the regulation of basal ganglia function and implications for the treatment of Parkinson's disease. Journal of Pharmacology and Experimental Therapeutics, 340(3), 595-603. Xiao, C., Shao, X. M., Olive, M. F., Griffin III, W. C., Li, K. Y., Krnjević, K., ... & Ye, J. H. (2009). Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area. Neuropsychopharmacology, 34(2), 307. Xiao, C., Miwa, J. M., Henderson, B. J., Wang, Y., Deshpande, P., McKinney, S. L., & Lester, H. A. (2015). Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus. Journal of Neuroscience, 35(9), 3734-3746. Xu-Friedman, M. A., & Regehr, W. G. (2004). Structural contributions to short-term synaptic plasticity. Physiological Reviews, 84(1), 69-85. Xu, F., & Wu, K. (2005). Guided-wave and leakage characteristics of substrate integrated waveguide. IEEE Transactions on microwave theory and techniques, 53(1), 66-73. Yajeya, J., De La Fuente, A., Criado, J. M., Bajo, V., Sánchez‐Riolobos, A., & Heredia, M. (2000). Muscarinic agonist carbachol depresses excitatory synaptic transmission in the rat basolateral amygdala in vitro. Synapse, 38(2), 151-160. Yelnik, J. (2002). Functional anatomy of the basal ganglia. Movement disorders, 17(S3), S15-S21. Yin, H. H. (2014). Action, time and the basal ganglia. Philosophical Transactions of the Royal Society of London B: Biological Sciences, 369(1637), 20120473. Zeef, D., Schaper, F., Vlamings, R., Visser-Vandewalle, V., & Temel, Y. (2011). Deep brain stimulation in Huntington’s disease: the current status. Open Neurosurg J, 4, 7-10. Zhang, L., & Warren, R. A. (2002). Muscarinic and nicotinic presynaptic modulation of EPSCs in the nucleus accumbens during postnatal development. Journal of neurophysiology, 88(6), 3315-3330. Zhou, F.-M. and J. J. Hablitz (1999). 'Dopamine Modulation of Membrane and Synaptic Properties of Interneurons in Rat Cerebral Cortex.' J. Neurophysiol. 81(3): 967-976. Zhou, F. M., Wilson, C. J., & Dani, J. A. (2002). Cholinergic interneuron characteristics and nicotinic properties in the striatum. Journal of neurobiology, 53(4), 590-605. Zucker, R. S., & Regehr, W. G. (2002). Short-term synaptic plasticity. Annual review of physiology, 64(1), 355-405. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/71466 | - |
dc.description.abstract | 基底核(basal ganglia)藉由錯綜複雜的神經網路系統與大腦皮層(cortex)做連結,由數個腦核區所組成,包含紋狀體(striatum)、視丘下核(subthalamic neucleus)、蒼白球(globus pallidus)及黑質(substantia nigra)。其主要的功能為人體運動的控制,並且在認知、行為、情感等方面上也扮演一重要的角色。而在基底核內部的神經網路可以分為直接迴路、間接迴路與超直接迴路。本篇主要探討各種神經調控物質(neuromodulator)在基底核的輸出核區:STN對外側蒼白球與內側蒼白球的調控作用。我們使用C57BL/6 mice製作大腦切片進行實驗,在視丘下核處給予電刺激,並且在小鼠的蒼白球進行whole-cell voltage clamp,分別記錄外側蒼白球與內側蒼白球的AMPAR glutamate ligand-gated channel的電流,並且加入acetylcholine、dopamine等神經修飾物質之致效劑與拮抗劑的方式,來觀察藥物對此突觸訊息傳遞之影響效果。研究結果顯示,當我們給予pair-pulse電刺激(間隔分別為100、50、20 ms,亦即約當10、20、50 Hz之刺激)時,在加入A68930 (D1 agonist)時,GPe和GPi的AMPA電流在第一下刺激(P1)的電流大小與PPR皆沒有顯著影響。同樣地用SKF83566 (D1 antagonist)檢測時,對GPe和GPi的P1大小與PPR也沒有顯著影響。而加入Quinpirole (D2 agonist)後,對GPe和GPi的P1電流皆下降2到3成,但對PPR則產生上升的趨勢。給予Eticlopride (D2 antagonist),對GPe和GPi的P1電流與PPR皆沒有顯著影響。在acetylcholine實驗中,我們發現加入carbachol (cholinergic agonist)時,對GPi做連續五下的電刺激,10、20、50 Hz等3個頻率組別的P1電流皆下降4成,且PPR皆稍微上升,但沒有上升到產生顯著差異;另外P5/P1 ratio也有上升的趨勢,但僅10 Hz、20 Hz組別上升達顯著差異(control組各為0.76、0.73,給予carbachol後約各為0.85、0.89)。另一方面,加入nicotine後,對GPe和GPi的P1大小與PPR皆沒有顯著影響,但在加入mecamylamine (nicotinic antagonist)後GPe和GPi的PPR有些微上升的趨勢,但不影響P1電流大小。然而在加入muscarine後,GPe和GPi的P1電流皆顯著下降6~7成,且PPR皆有稍微上升的現象。這些結果顯示,acetylcholine對視丘下核到GPe、GPi的glutamatergic有顯著調控突觸電流的功能,並且,在我們的實驗條件下發現可能是經由muscarine受體去作修飾調控。 | zh_TW |
dc.description.abstract | The basal ganglia are comprised of striatum, subthalamic nucleus (STN), globus pallidum and substantia nigra. They work in concert with the cortex, thalamus, and brain stem and play an important role in many different functions, including voluntary motor control, cognitive, behavior, and emotional functions. The cortico-subcortical re-entrant loops always involve basal ganglia, and can be divided into direct, indirect and hyperdirect pathways. We endeavored to investigate the effect of different neuromodulators on the Glutamatergic synaptic transmission from STN to GPe and STN to GPi, and evoked excitatory postsynaptic currents (EPSCs) separately from STN to GPe and STN to GPi in C57BL/6 mouse brain slices with whole-cell voltage-clamp technique. Pair pulse stimuli in 3 different frequencies (10、20 and 50 Hz) were applied to the STN to GPe and STN to GPi fibers, respectively, to evoke EPSCs. We found that D1 agonist (A68930) has no apparent effect on P1 amplitude and PPR in both STN-GPe and STN-GPi synaptic transmission. D1 antagonist (SKF83566) affects neither P1 amplitude nor PPR in both STN-GPe and STN-GPi. D2 agonist (Quinpirole) decreases P1 amplitude by 20~30% and slightly increases PPR in both STN-GPe and STN-GPi pathway. D2 antagonist (Eticlopride) affects neither P1 amplitude nor PPR of STN-GPe and STN-GPi. We also examined the effect of acetylcholine modulated STN-GPe and STN-GPi synaptic transmission. With a 5-pulse stimulation protocol in GPi, we found that carbachol markedly decreases P1 amplitude and slightly increases both P2/P1 and P5/P1 ratios in STN-GPi. While nicotine has no effect on both P1 amplitude and PPR in STN-GPe and STN-GPi, nicotine antagonist (mecamylamine) shows a tendency to increase PPR in both STN-GPe and STN-GPi but causes no change to P1 amplitude. Muscarine significantly decreases P1 amplitude by 60~70% and slightiy increases PPR in both STN-GPe and STN-GPi. We therefore conclude that both STN-GPe and STN-GPi AMPAergic transmissions are significantly modulated by acetylcholine via muscarinic receptor and slightly modulated by dopamine via dopamine D2 receptor. | en |
dc.description.provenance | Made available in DSpace on 2021-06-17T06:01:14Z (GMT). No. of bitstreams: 1 ntu-108-R05441014-1.pdf: 6639022 bytes, checksum: 11fa3f19229c20d28c29565b7e6fc517 (MD5) Previous issue date: 2019 | en |
dc.description.tableofcontents | 誌謝 i
摘要 ii Abstract iv 目錄 vi 圖目錄 ix 壹、導論 1 1.1 基底核 (basal ganglia) 1 1.1.1 基底核中的神經傳遞路徑 2 1.1.2 基底核中主要核區的特性 4 1.2 外側蒼白球的神經連結 10 1.2.1 傳入外側蒼白球的連結 (Afferent connections) 10 1.2.2 外側蒼白球傳出的連結 (Efferent connections) 11 1.2.3 視丘下核傳入外側蒼白球的重要性 12 1.3 突觸可塑性對突觸訊息傳遞的影響 13 1.4 視丘下核與蒼白球上的受體 14 1.5 受體的生理功能 15 1.5.1 多巴胺 (Dopamine) 15 1.5.2 乙醯膽鹼 (Acetylcholine) 16 1.6 視丘下核與蒼白球在疾病生理上和疾病治療上所扮演的角色 19 1.6.1 巴金森氏症 (Parkinson’s disease, PD) 19 1.6.2 亨丁氏舞蹈症 (Huntington’s disease, HD) 21 貳、 材料與方法 22 2.1 實驗動物 22 2.2 腦切片的製備 22 2.3 玻璃電極的製備 23 2.4 壓片器 23 2.5 細胞電生理紀錄以及電刺激 23 2.6 藥品 25 2.7 數據取得分析 28 參、 結果 29 3.1 STN-GPe和STN-GPi glutamatergic突觸電流 29 3.2 A68930對STN-GPe和STN-GPi的AMPA突觸電流沒有顯著的影響 ………………………………………..……………………………….30 3.3 SKF83566對STN-GPe和STN-GPi的AMPA突觸電流沒有顯著的影響 31 3.4 Quinpirole對STN-GPe和STN-GPi的AMPA突觸電流有輕微的抑制作用 31 3.5 Eticlopride對STN-GPe和STN-GPi的AMPA突觸電流沒有顯著的影響 32 3.6 Carbachol對STN-GPi的AMPA突觸電流有抑制性作用 33 3.7 Nicotine對STN-GPe和STN-GPi的AMPA突觸電流沒有顯著的影響……………………………………………………………………..…34 3.8 Mecamylamine對STN-GPe和STN-GPi的AMPA突觸電流沒有顯著的影響 35 3.9 Muscarine對STN-GPe和STN-GPi的AMPA突觸電流有明顯的抑制作用 36 肆、 討論 38 4.1 Dopamine的調控功能 40 4.2 Acetylcholine的調控功能 42 4.3 神經調控物質對STN-GPe和STN-GPi可能具有生理或病理上的意 義.. 45 伍、 參考資料 79 | |
dc.language.iso | zh-TW | |
dc.title | 多巴胺及乙醯膽鹼對視丘下核到外側和內側蒼白球麩胺酸突觸傳導之修飾作用 | zh_TW |
dc.title | Dopaminergic and cholinergic modulation of subthalamopallidal glutamatergic synaptic transmission | en |
dc.type | Thesis | |
dc.date.schoolyear | 107-1 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 蔡明正(Ming-Cheng Tsai),楊雅晴(Ya-Chin Yang) | |
dc.subject.keyword | 視丘下核,外側蒼白球,內側蒼白球,突觸傳遞,電生理, | zh_TW |
dc.subject.keyword | subthalamic nucleus,external globus pallidus,internal globus pallidus,synaptic transmission,electrophysiology, | en |
dc.relation.page | 97 | |
dc.identifier.doi | 10.6342/NTU201900474 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2019-02-12 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 生理學研究所 | zh_TW |
顯示於系所單位: | 生理學科所 |
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