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請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/70660
完整後設資料紀錄
DC 欄位值語言
dc.contributor.advisor張弘潔(HUNG-CHIEH CHANG)
dc.contributor.authorJaylynn Ellingtonen
dc.contributor.author艾珍琳zh_TW
dc.date.accessioned2021-06-17T04:34:04Z-
dc.date.available2021-02-23
dc.date.copyright2021-02-23
dc.date.issued2021
dc.date.submitted2021-02-18
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dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/70660-
dc.description.abstractIntroduction: The ancillary effects of school-based policies implemented during the COVID-19 pandemic in Taiwan in protecting children aged 3-19 from other respiratory infections, including influenzas and enterovirus, has been mostly obscured.

Objective: In this study, the collateral benefits of Taiwan’s Ministry of Education COVID-19 school-based prevention regulations are evaluated in terms of protecting children from both severe influenza and enterovirus infections with severe complications.
Data Source: Secondary data used in this investigation was obtained from the Taiwan Centers for Disease Control for the period from January 2018 to June 2020.

Methodology: This was a natural experiment to make a causal inference about the efficacy of the Taiwan’s Ministry of Education COVID-19 school-based prevention regulations in protecting children from influenza and enterovirus using secondary data. Scatterplots and time series plots were used to inspect the data for seasonal patterns, outliers visually, and trends in the incidence of influenza and enterovirus, respectively. Unpaired t-tests were used to examine whether the difference in the mean number of influenza and enterovirus cases in the pre-intervention and post-intervention period was significantly different. An interrupted time-series regression based on the level change impact model and Poisson regression for counts was fitted to determine whether Taiwan’s Ministry of Education COVID-19 school-based prevention regulations had an impact on the number of reported cases for both diseases. Sensitivity analyses were performed to correct for overdispersion and autocorrelation.
Results: The unadjusted interrupted time series (ITS) regression models assuming a level change impact model revealed a strong and statistically significant influence of Taiwan’s Ministry of Education school-based regulations implemented during the COVID-19 pandemic on the incidence of influenza among Taiwanese children, with a reduction of 235% (relative risk (RR)= 0.0950; 95% confidence interval (CI) [0.0244– 0.2738]; p<0.05). Similarly, the incidence of enterovirus with severe complications reduced by 257% (relative risk (RR)= 0.0762; 95% confidence interval (CI) [0.0065– 0.3433]; p<0.05).
Conclusion: This study shows that after the Taiwan’s Ministry of Education COVID-19 school-based preventive measures were implemented, the severe cases of influenza and enterovirus among children aged 3 to 19 years decreased significantly, which demonstrates the effectiveness of the policies. Findings from this research are likely to revolutionize how the public perceives public health policies such as facemask use and school operation during a pandemic especially in places that lack capacity to how class online, following evidence of reductions in other respiratory illnesses among children.
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Previous issue date: 2021
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dc.description.tableofcontentsTABLE OF CONTENTS
ABSTRACT ii
TABLE OF CONTENTS iv
LIST OF FIGURES vii
LIST OF TABLES viii
CHAPTER ONE: INTRODUCTION 1
1.1 Overview 1
1.2 Case of Taiwan 1
1.3 Face Mask, Social Distancing, and Handwashing Prevention Measures 2
1.4 Preventive Policies Used to Comeback the Spread of Infectious in Taiwan 3
1.4.1 Impacts of COVID-19 Policies in Taiwan 4
1.5 Problem Statement 5
1.6 Objectives 7
1.6.1 Broad Objective 7
1.6.2 Specific Objectives 7
1.7 Research Questions 7
1.8 Study Justification 8
CHAPTER TWO: LITERATURE REVIEW 10
2.0 Introduction 10
2.1 Infectious Respiratory Diseases and Child Health 10
2.2.3 Coronavirus Disease (COVID-19) 12
2.3 Community Interventions Against a Pandemic 13
2.4 Policies in Taiwan 13
2.5 Historical Examples of Respiratory Diseases in Taiwan and Their Impact on Children 14
2.5.1 Enterovirus: History, Incidence, and Mortality in Taiwan 15
2.5.2 Influenza: History, Incidence, and Mortality in Taiwan 18
2.5.3 Severe Acute Respiratory Syndrome (SARS): History, Incidence, and Mortality in Taiwan 22
2.5.4 COVID- 19: History, Incidence, and Mortality in Taiwan 24
2.6 Interventions for Respiratory Disease Epidemics in Taiwan 27
2.6.1 Interventions for the Enterovirus Epidemic in Taiwan. 27
2.6.2 Interventions for Influenza-based Epidemics and Infections in Taiwan 27
2.6.3 Interventions for SARS-CoV Infections in Taiwan 28
2.6.4 Interventions for the COVID-19 Pandemic in Taiwan 28
2.7 Global Face mask Policies and History of Face Masks 29
2.8 COVID-19 Policies in Taiwan (MOE COVID-19 Regulations). 32
CHAPTER THREE: METHODOLOGY 35
3.0 Introduction 35
3.1 Setting and Study Population 35
3.2 Study Design 36
3.2.1 Natural experimental study design 36
3.2.2 Interrupted Time-Series Study Design 37
3.3 Data Source 37
3.4 Statistical and Data Analysis Procedures (ITS) 38
3.4.1 Intervention 38
3.4.2 The outcome 38
3.4.3 Evaluation of the Health Impact of the Intervention (MOE school-based guidelines) 39
3.4.4 Descriptive and Exploratory Data Analyses 39
3.4.5 Regression modeling 40
3.4.5 Sensitivity analysis 41
3.5 Statistical Analysis Software and Data availability 41
3.6 Ethical Considerations 41
3.7 Expected Applications 41
CHAPTER FOUR: RESULTS 43
4.0 Introduction 43
4.1 COVID-19 Policy Analysis 43
4.1 Exploratory Data Analysis 47
4.1.1 Descriptive Analysis 47
CHAPTER FIVE: DISCUSSION 61
5.0 Introduction 61
5.1 The Role of School Based Policies Implemented During COVID-19 61
5.2 Study implications 67
5.2.1 The Importance of Examining COVID-19 Policies' Effects on Children and Schools 68
5.2.2 Taiwan's Ministry of Education's 'Guidelines for University and College Preventative Measures against COVID-19' 69
5.2.3 Brief International Comparison 70
5.3 Study Strengths 71
5.4 Study Limitations 72
5.5 Recommendations for Future Work 72
CHAPTER SIX: CONCLUSIONS AND RECOMMENDATIONS 74
6.0 Introduction 74
6.1 Conclusion 74
6.2 Recommendations 75
REFERENCES 77
dc.language.isoen
dc.subjectInfluenzazh_TW
dc.subjectschool pandemic operation guidelineszh_TW
dc.subjectCOVID-19zh_TW
dc.subjectTaiwanzh_TW
dc.subjectEnteroviruszh_TW
dc.subjectschool-based policieszh_TW
dc.subjectunadjusted interrupted time series (ITS) regression modelszh_TW
dc.title台灣3至19歲兒童COVID-19 預防措施之附帶效益的間斷時間序列分析zh_TW
dc.titleInterrupted Time Series Analysis of the Ancillary Benefits of COVID-19 Prevention Measures in Children Aged 3 to 19 Years in Taiwanen
dc.typeThesis
dc.date.schoolyear109-1
dc.description.degree碩士
dc.contributor.oralexamcommittee林先和(Hsien-Ho Lin),張齡尹(LING-YIN CHANG)
dc.subject.keywordEnterovirus,Influenza,unadjusted interrupted time series (ITS) regression models,school-based policies,school pandemic operation guidelines,COVID-19,Taiwan,zh_TW
dc.relation.page90
dc.identifier.doi10.6342/NTU202100725
dc.rights.note有償授權
dc.date.accepted2021-02-18
dc.contributor.author-college公共衛生學院zh_TW
dc.contributor.author-dept全球衛生碩士/博士學位學程zh_TW
顯示於系所單位:全球衛生學位學程

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