請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/6798完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 鄭守夏 | |
| dc.contributor.author | Yi-Jing Kuo | en |
| dc.contributor.author | 郭奕靚 | zh_TW |
| dc.date.accessioned | 2021-05-17T09:18:20Z | - |
| dc.date.available | 2017-09-17 | |
| dc.date.available | 2021-05-17T09:18:20Z | - |
| dc.date.copyright | 2012-09-17 | |
| dc.date.issued | 2012 | |
| dc.date.submitted | 2012-07-17 | |
| dc.identifier.citation | 中文部分
中央健康保險局(2005)。全民健康保險慢性病連續處方箋調劑作業要點,健保醫字第84001242 號。 中央健康保險局(2006a)。慢性病範圍。2012年5月01日,取自: http://www.nhi.gov.tw/webdata/webdata.aspx?menu=18&menu_id=683&webdata_id=444&WD_ID=761 中央健康保險局(2006b)。全民健康保險費用協定委員會第112次委員會議-中央健康保險局醫療費用支出情形報告。2012年1月10日,取自: http://www.nhi.gov.tw/resource/Webdata/Attach_5741_1_112次業務報告.doc 中央健康保險局(2011)。挑戰2025 糖尿病醫療國際論壇, http://www.nhi.gov.tw/epaper/ItemDetail.aspx?DataID=2667&IsWebData=0&ItemTypeID=7&PapersID=227&PicID= 中華民國糖尿病協會(2007)。台灣糖尿病宣言。2012年4月10日,取自: http://www.endo-dm.org.tw/dia/dia_worldword.asp 世界衛生組織(2012)。2012年4月10日,取自: http://www.who.int/en/ 台灣食品藥物管理局(2010),第二型糖尿病治療藥物梵帝雅(Avandia)加強警語說明,藥物食品安全週報,第254期。 台灣醫療改革基金會(2009)。憑慢性病處方箋領藥每人每年最多可省 6,480 元慢性病患聰明就醫領藥不可不知。2012年5月10日,取自: http://www.thrf.org.tw/Page_Show.asp?Page_ID=927 全民健康保險慢性病連續處方箋調劑作業要點(1999)。 全民健康保險醫療辦法(2009)。 羊儀珊(2008)。高血壓病患開立慢性病連續處方箋對醫療利用的影響。國立陽明大學醫務管理研究所碩士論文。 何蘊芳、林慧玲、蔡瑜珍、邱士峰、 賴玉花、何富蕙、林芬如等人(2006)。門診患者對慢性病連續處方箋的認知。台灣醫學, 10(5), 578-585。 李姝慧(2010)。糖尿病連續處方箋對醫療照護結果品質之影響評估--以中部某醫學中心為例。中國醫藥大學醫務管理學研究所碩士論文。 林世崇(2010)。糖尿病治療的新策略。台灣醫界,53(9),16-23。 76 周麗芳、陳曾基(1999)。評析全民健保慢性病連續處方箋措施。台灣醫界, 42(10), 45-51。 莊秋金 (2004)。高血壓病患使用慢性病連續處方箋對高血壓門診醫療利用之影響。國立陽明大學衛生研究所碩士論文。 陳立佳、曾如慧 (2008)。全民健康保險降血糖藥物之用藥型態及使用評估。行政院衛生署中央健康保險局委託研究計劃。 陳鴻儀 (2004)。釋出慢性病連續處方箋可行機制之研究調查--病人之觀點。行政院衛生署九十三年度科技研究發展計畫報告,10-11。 黃美玲(2001)。門診部分負擔對老年民眾醫療利用影響之研究。國立台灣大學會計學研究所碩士論文。 黃展偉、黃國晉、楊偉勛(2010)。2010年美國糖尿病學會臨床指引摘要。家庭醫學與基層醫療,25(8),298-304。 黃碧玉 (2007)。糖尿病患者使用慢性病連續處方箋對門診醫療利用之影響。國立台灣大學公共衛生學院衛生政策與管理研究所碩士論文。 董千儀、林慧玲、林昌誠、林素真、何藴芳等人 (2008)。民眾對醫院與社區藥局慢性病連續處方調劑服務的觀感。台灣醫學, 12(6),635-643。 衛生署統計室網站 (2012)。2012年4月10日,取自: http://www.doh.gov.tw/CHT2006/DM/DM2_p01.aspx?class_no=117&now_fod_list_no=4146&level_no=1&doc_no=38031 蔡明足、翁林仲、蔡維河、蔡景耀、周歆凱、林敬恆(2008)。台灣地區糖尿病患及其視網膜病變的醫療資源耗用。台灣公共衛生雜誌,27(2), 101-08。 蔡佳玲 (2009)。慢性病連續處方箋之成效評估-以資料探勘技術探討未開立慢性病連續處方之決定因子。中正大學資訊管理研究所碩士論文。 謝永宏、劉孟基、徐俊生、陳偉智、陳俊源 (2010)。國內外藥物回收計畫及執行計畫報導。藥學雜誌,26(1), 82-87。 蘇浩然 (2011)。健保藥價調整在不同藥品市場競爭特質下對於處方型態之影響: 以口服降血糖用藥長期分析。台灣大學健康政策與管理研究所碩士論文。 龔佩珍、呂嘉欣、蔡文正 (2007)。基層醫師釋出慢性病連續處方箋之意願及相關因素。台灣公共衛生雜誌,26(1), 26-37。 77 英文部分 American Diabetes Association. (2012a). Diabetes basics, Retrieved from http://www.diabetes.org/diabetes-basics/diabetes-statistics/ American Diabetes Association. (2012b). Standards of Medical Care in Diabetesd--2012. Diabetes Care, 35. Adrade, S. E., Kahler, K. H., Frech, F., & Chan A. (2006). Methods for evalution of adherence and persistence using automated databases. Pharmacoepidemiology and Drug Safty, 15, 565-547. Asche, C., LaFleur, J., & Conner, C. (2011). A Review of Diabetes Treatment Adherence and the Association with Clinical and Economic Outcomes. Clinical Therapeutics, 33(1), 74-109. Balkrishnan, R., Rajagopalan, R., & Camacho, F. T. (2003). Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: A longitudinal cohort study. Clinical Therapeutics, 25, 2958–2971. Bloom, D. E., Cafiero, E.T., Jane-Llopis, E., Abrahams-Gessel, S., Bloom, L.R., Fathima, S., Feigl, A.B., Gaziano, T., Mowafi, M., Pandya, A., Prettner, K., Rosenberg, L., Seligman, B., Stein, A., & Weinstein, C. (2011). The Global Economic Burden of Non-communicable Diseases. Boulton, A. J., Vinik, A. I., Arezzo, J.C., Bril, V., Feldman, E. L., Freeman, R., Malik, R. A., Maser, R. E., Sosenko, J. M., & Ziegler, D. (2005). Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care, 28, 956. Centers for Disease Control and Prevention. (2011). National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. Cheng, S. H., Chiang, T. L. (1997). The effect of universal health insurance on health care utilization. JAMA, 278, 89-93. Colombi, A. M., Yu-Isenberg, K., Priest, J. (2008). The effects of health plan copayments on adherence to oral diabetes medication and health resource utilization. Journal of Occupational and Environmental Medicine, 50,535–541. Cowper, P. A., Weinberger, M., & Hanlon, J. T. (1998). The cost-effectiveness of a clinical pharmacist intervention among elderly outpatients. Pharmacotherapy, 78 18, 327-332. De Smet, P. A. G. M., & Dautzenberg, M. (2004). Repeat Prescribing--Scale, Problems and Quality Management in Ambulatory Care Patients. Drugs, 64 (16), 1779-1800. DiPiro, J. T., Talbert, R. L., Yee, G. C., Matzke, G. R., Wells, B. G., & Posey, L. M.. (2008). Pharmacotherapy (7th ed.). United States of America: McGraw-Hill Companies. Ellis, S. L., Carter, B. L., & Malone, D. C. (2000). Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: the IMPROVE study. Impact of Managed Pharmaceutical Care on Resource Utilization and Outcomes in Veterans Affairs Medical Centers. Pharmacotherapy, 20, 1508-1516. FDA, (2011) FDA Drug Safety Communication: Updated Risk Evaluation and Mitigation Strategy (REMS) to Restrict Access to Rosiglitazone-containing Medicines including Avandia, Avandamet, and Avandaryl. Retrieved from http://www.fda.gov/Drugs/DrugSafety/ucm255005.htm Fong, D. S., Aiello, L. P., Ferris, F. L. 3rd, & Klein, R. (2004). Diabetic retinopathy. Diabetes Care, 27. Fowler, M. J. (2011). Microvascular and Macrovascular Complications of Diabetes. Clinical Diabetes, 29. Gardner, C. D., Kiazand, A., Alhassan, S., Kim, S., Stafford, R. S., Balise, R. R., Kraemer, H. C., & King, A. C. (2007). Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA, 297. Hanlon, J. T., Weinberger, M., & Samsa, G. P. (1996). A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly outpatients with polypharmacy. American Journal of Medicine, 100, 428-437. Harris, C. M., & Dajda, R. (1996). The scale of repeat prescribing. The British Journal of General Practice, 46, 649-653. Hepke, K. L., Martus, M. T., & Share, D. A. (2004). Costs and utilization associated with pharmaceutical adherence in a diabetic population. American Journal of Managed Care, 10, 144-151. 79 Hepler, C. D., & Strand, L. M. (1990). Opportunities and responsibilities in pharmaceutical care. American Journal of Hospital Pharmacy, 47, 533-543. Hogan, P., Dall, T., & Nikolov, P. (2003). Economic costs of diabetes in the US in 2002. Diabetes Care, 26, 917–932. Jameson, J. P., & VanNoord, G. R. (2001). Pharmacotherapy consultation on polypharmacy patients in ambulatory care. The Annals of Pharmacotherapy, 35, 835-840. Kleinman, N. L., Schaneman, J. L., Lynch, W. D. (2008). The association of insulin medication possession ratio, use of insulin glargine, and health benefit costs in employees and spouses with type 2 diabetes. Journal of Occupational and Environmental Medicine, 50, 1386–1393. Krska, J., Cromarty, J. A., & Arris, F. (2001). Pharmacist-led medication review in patients over 65: a randomized, controlled trial in primary care. Age Ageing, 30, 205-211. Laing, S. P., Swerdlow, A. J., Slater, S. D., Burden, A. C., Morris, A., Waugh, N. R., Gatling, W., Bingley, P. J., & Patterson, C. C. (2003). Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes. Diabetologia, 46, 760–765. Lau, D. T., & Nau, D. P. (2004). Oral antihyperglycemic medication nonadherence and subsequent hospitalization among individuals with type 2 diabetes. Diabetes Care, 27, 2149-2153. Lawrence, D. B., Ragucci, K. R., & Long, L. B. (2006). Relationship of oral antihyperglycemic (sulfonylurea or metformin) medication adherence and hemoglobin A1c goal attainment for HMO patients enrolled in a diabetes disease management program. Journal of Managed Care Pharmacy., 12, 466-471. Lehto, S., Ronnemaa, T., Pyorala, K., & Laakso, M. (1996). Predictors of stroke in middle-aged patients with non-insulin-dependent diabetes. Stroke, 27, 63–68. Leung, G. M., & Lam, K. S. L. (2006). Diabetic complications and their implications on health care in AsiaDiabetic complications and their implications on health care in Asia. Hong Kong Medical Journal, 6, 61-68. Lin, C. C., Lai, M. S., Syu, C. Y., Chang, S. C., & Tseng, F. Y. (2005). Accuracy of diabetes dignosis in health insurance claims in Taiwan. Journal of the Formosan Medical Association, 104,157-63. 80 Lowe, C. J., Raynor, D. K., & Purvis, J. (2000). Effects of a medicine review and education programme for older people in general practice. British Journal of Clinical Pharmacology, 50, 172-175. National Collaborating Centre for Chronic Conditions. (2008). Type 2 diabetes: national clinical guideline for management in primary and secondary care (update). London: Royal College of Physicians. Parsons, L. S. (2001). Reducing bias in a propensity score matched-pair sample using greedy matching techniques. In: Proceedings of the Twenty-Sixth Annual SASR Users Group International Conference. Cary, NC: SAS Institute Inc, 2001. Paterson, A. D., Rutledge, B. N., Cleary, P. A., Lachin, J. M., & Crow, R. S. (2007). The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study. Diabetes Care, 30, 2107–2112. Schillinger, D., Piette, J., Grumbach, K., Wang, F., Wilson, C., Daher, C., & Bindman, A. B. (2003). Closing the loop: physician communication with diabetic patients who have low health literacy. Archives of Internal Medicine, 163(1), 83. Sellors, J., Kaczorowski, J., & Sellors, C. (2003). A randomized controlled trial of a pharmacist consultation program for family physicians and their elderly patients. Canadian Medical Association Journal, 169, 17-22. Shenolikar, R. A., Balkrishnan, R., & Camacho, F. T. (2006). Comparison of medication adherence and associated health care costs after introduction of pioglitazone treatment in African Americans versus all other races in patients with type 2 diabetes mellitus: A retrospective data analysis. Clinical Therapeutics., 28, 1199-1207. Straand, J., & Rokstad, K. S. (1999). Elderly patients in general practice: diagnoses, drugs and inappropriate prescriptions: a report from the More & Romsdal Prescription Study. Family Practice, 16, 380-388. Whiting, D. R., Guariguata, L., Weil, C., & Shaw, J. (2011). IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Atlas, 94, 311-21. WHO Media Centre. (2012). Fact sheet No. 312 'Diabetes'. Retrived April 10, 2011, from http://www.who.int/mediacentre/factsheets/fs312/en/index.html Wild, S., Sicree, R., Roglic, G., King, H., & Green, A. (2004). Global Prevalence of 81 Diabetes-Estimates for the year 2000 and projections for 2030. Diabetes Care, 27 (5). Wolf, M. S., Gazmararian, J. A., Baker, D. W. (2005). Health literacy and functional health status among older adults. Archives of Internal Medicine, 165, 1946-52. World Economic Forum. (2011). From Burden to “Best Buys”: Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income Countries | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/6798 | - |
| dc.description.abstract | 背景 依據衛生署統計資料,台灣糖尿病盛行率約4.3%,估計共約有100萬名糖尿病病人。健保局一年花在糖尿病上的費用達184億元,醫療負擔相當驚人。慢性病的治療與控制需要長期而持續地就醫用藥。為加強對慢性疾病病人的照顧,健保局自1995年起大力推動慢性病連續處方箋制度。
目的 本研究旨在評估慢性病連續處方箋所造成健康照護與醫療資源耗用影響。 方法 本研究利用2003-2005年健保資料庫糖尿病特殊需求檔,將口服糖病用藥穩定之第二型糖尿病人分為無慢箋組、間歇慢箋組與持續慢箋組,以無慢箋組之特性對另外兩組進行傾向分數配對,以配對後三組比較不同慢箋使用特性族群之醫療資源耗用情形與健康照護結果。 結果 配對後樣本無慢箋組、間歇慢箋組、持續慢箋組各16560人。連續處方箋使用對健康照護結果影響部分,以糖尿病相關急診與住院次數做為健康照護結果指標,結果無慢箋組次數最多,間歇慢箋組次之,持續慢箋組最少,亦即持續慢箋組有最佳之健康照護結果 (p<0.01)。醫療資源耗用部分,以糖尿病相關/總醫療花費、糖尿病相關/門診醫療花費與糖尿病相關/門診就診次數為指標皆顯示持續慢箋組有最少之花費,間歇慢箋組次之,無慢箋組最多 (p<0.01)。 結論 糖尿病人使用慢性病連續處方箋,有較佳的健康照護結果,且有較低的醫療資源耗用,皆未見明顯的負面影響。 | zh_TW |
| dc.description.abstract | According to the statistics of the Department of Health, the prevalence of diabetes is about 4.3% in Taiwan and there are about 1 million diabetes patients. For taking care of chronic disease patients, the Bureau of National Health Insurance implemented the prescription refill policy. However, diabetes has been a heavy burden of the health care system in Taiwan. This research is conducted to evaluate the impacts prescription refills has on the health care resources utilization and the health care outcome in Taiwan. We use the NHI claims data from 2003-2005, identifying different prescription-refill-usage characteristics into 3 groups: the sustain-use group, the intermittent-use group, and the never-use group. We choose the never-use group as the control group and select the intervention group from the sustain-use and the intermittent-use group by propensity score matching to construct a comparable matching group. The total sample size is 49680 (16560 each group). Subsequently, we take a generalized equation estimate (GEE) approach to compare the likelihood of the health care resources utilization and the health care outcome among the three groups. While using the diabetes related hospitalization and emergency utilization as the indictors of the health care outcome, the frequency are the sustain-use < the intermittent-use < the never-use group (p<0.01). On the other hand, the health care resources utilization is sustain-use < the intermittent-use< the never-use group (p<0.01) as well. That is, diabetes patients who using prescription refills have better health care outcome and lower health care resources utilization in Taiwan. | en |
| dc.description.provenance | Made available in DSpace on 2021-05-17T09:18:20Z (GMT). No. of bitstreams: 1 ntu-101-R99848007-1.pdf: 1084121 bytes, checksum: ea5deead77a6e010fa0d17848a86081e (MD5) Previous issue date: 2012 | en |
| dc.description.tableofcontents | 致謝 ............................................................... II
中文摘要 .......................................................... III ABSTRACT ........................................................ IV 目錄 ................................................................ V 第一章 緒論 ...................................................... 1 第一節 研究背景 ............................................................................................................................ 1 第二節 研究動機與問題 ................................................................................................................. 2 第三節 研究目的與重要性 ............................................................................................................. 2 第二章 文獻回顧 .................................................. 3 第一節 糖尿病簡介......................................................................................................................... 3 (一) 糖尿病的診斷 .................................................................................................................. 3 (二) 糖尿病相關併發症 .......................................................................................................... 4 (三) 糖尿病流行病學 .............................................................................................................. 5 (四) 糖尿病治療目標 .............................................................................................................. 6 (五) 糖尿病治療藥物 .............................................................................................................. 7 第二節 慢性病連續處方箋政策 ..................................................................................................... 9 第三節 國外連續處方箋相關研究 ................................................................................................. 9 (一) 連續處方箋制度 ............................................................................................................ 10 (二) 連續處方箋與健康照護結果 ........................................................................................ 11 (三) 連續處方箋與醫療資源耗用 ........................................................................................ 11 (四) 連續處方箋與調劑順從度 ............................................................................................ 12 第四節 國內連續處方箋相關研究 ............................................................................................... 13 (一) 連續處方箋使用行為 .................................................................................................... 13 (二) 連續處方箋與健康照護結果 ........................................................................................ 13 (三) 連續處方箋與醫療資源利用 ........................................................................................ 13 第五節 小結 .................................................................................................................................. 15 第三章 研究材料與方法 ........................................... 16 第一節 研究架構 .......................................................................................................................... 16 第二節 資料處理流程................................................................................................................... 18 第三節 變項定義 .......................................................................................................................... 26 第四節 研究假說 .......................................................................................................................... 32 第五節 統計分析 .......................................................................................................................... 33 第四章 研究結果 ................................................. 34 VI 第一節 配對前後樣本特質 ............................................................................................................ 34 (一)整體糖尿病人基本資料 ........................................................................................................ 34 (二)連續處方箋分組後樣本特性描述 ........................................................................................ 36 (三)配對後樣本特性描述 ............................................................................................................ 38 (四)配對前後特性比較 ................................................................................................................ 39 第二節 多變項分析 ........................................................................................................................ 54 (一)連續處方箋對健康照護結果影響 ........................................................................................ 54 (二)連續處方箋對醫療資源耗用影響 ........................................................................................ 54 (三)其他發現 ................................................................................................................................ 54 第五章 討論 ..................................................... 64 第一節 研究設計與方法討論 ........................................................................................................ 64 第二節 研究結果討論 .................................................................................................................... 67 第三節 研究限制 ............................................................................................................................ 72 第六章 結論與建議 ............................................... 73 第一節 結論 .................................................................................................................................... 73 第二節 政策與未來研究建議 ........................................................................................................ 74 參考文獻 ........................................................... 75 中文部分 ........................................................................................................................................... 75 英文部分 ........................................................................................................................................... 77 附錄 ............................................................... 82 | |
| dc.language.iso | zh-TW | |
| dc.title | 慢性病連續處方箋影響評估-以第二型糖尿病人為例 | zh_TW |
| dc.title | The Evaluation of Prescription Refills for Chronic Diseases: The Case of Type II Diabetes Care | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 100-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 楊銘欽,黃文鴻 | |
| dc.subject.keyword | 連續處方箋,醫療資源耗用,健康照護結果,糖尿病,傾向分數配對, | zh_TW |
| dc.subject.keyword | prescription refill,health care resources utilization,health care outcome,diabetes,propensity score matching, | en |
| dc.relation.page | 106 | |
| dc.rights.note | 同意授權(全球公開) | |
| dc.date.accepted | 2012-07-17 | |
| dc.contributor.author-college | 公共衛生學院 | zh_TW |
| dc.contributor.author-dept | 健康政策與管理研究所 | zh_TW |
| 顯示於系所單位: | 健康政策與管理研究所 | |
文件中的檔案:
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-101-1.pdf | 1.06 MB | Adobe PDF | 檢視/開啟 |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。
