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| ???org.dspace.app.webui.jsptag.ItemTag.dcfield??? | Value | Language |
|---|---|---|
| dc.contributor.advisor | 黃慧璧(Hui-Pi Huang) | |
| dc.contributor.author | Tzu-Chi Tai | en |
| dc.contributor.author | 戴子綺 | zh_TW |
| dc.date.accessioned | 2021-05-17T09:14:36Z | - |
| dc.date.available | 2015-08-28 | |
| dc.date.available | 2021-05-17T09:14:36Z | - |
| dc.date.copyright | 2012-08-28 | |
| dc.date.issued | 2012 | |
| dc.date.submitted | 2012-08-15 | |
| dc.identifier.citation | Chapter 1
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Falk JA, Kadiev S, Criner GJ, et al. Cardiac disease in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5:543-548. 21. Serres F, Chetboul V, Gouni V, et al. Diagnostic Value of Echo-Doppler and Tissue Doppler Imaging in Dogs with Pulmonary Arterial Hypertension. J Vet Intern Med 2007;21:1280-1289. 22. Guglielmini C, Civitella C, Diana A, et al. Serum cardiac troponin I concentration in dogs with precapillary and postcapillary pulmonary hypertension. J Vet Intern Med 2010;24:145-152. 23. Johnson L. Diagnosis of pulmonary hypertension. Clin Tech Small Anim Pract 1999;14:231-236. 24. Serres FJ, Chetboul V, Tissier R, et al. Doppler echocardiography–derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001–2005). J Am Vet Med Assoc 2006;229:1772-1778. 25. Kovacs G, Berghold A, Scheidl S, et al. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J 2009;34:888-894. 26. Kellihan HB. Pulmonary hypertension and pulmonary thromboembolism. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and the Cat, 2 ed. St. Louis: Saunders; 2010:1138-1141. 27. Steele JL, Henik RA. Pulmonary hypertension. In: King LG, ed. Textbook of Respiratory Disease in Dogs and Cats, 1 ed. St. Louis: Saunders; 2004:498-507. 28. Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 2009;30:2493-2537. 29. Gehlbach BK, Geppert E. The Pulmonary Manifestations of Left Heart Failure. Chest 2004;125:669-682. 30. Kellihan HB, Stepien RL. Pulmonary hypertension in canine degenerative mitral valve disease. J Vet Cardiol 2012;14:149-164. 31. Kitagawa H, Sasaki Y, Ishihara K, et al. Contribution of live heartworms harboring in pulmonary arteries to pulmonary hypertension in dogs with dirofilariasis. Jpn J Vet Sci 1990;52:1211-1217. 32. 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Role of the left atrium in adaptation of the heart to chronic mitral regurgitation in conscious dogs. Circ Res 1988;62:543-553. 45. Nakata H, Kado T, Fukuzaki H. Time lag between pulmonary congestion and pulmonary edema in dogs. Jpn Circ J 1986;50:433-441. 46. Delgado JF, Conde E, Sanchez V, et al. Pulmonary vascular remodeling in pulmonary hypertension due to chronic heart failure. Eur J Heart Fail 2005;7:1011-1016. 47. Aber CP, Campbell J. Significance of changes in the pulmonary diffusing capacity in mitral stenosis. Thorax 1965;20:135-145. 48. Haddad F, Doyle R, Murphy DJ, et al. Right ventricular function in cardiovascular disease, part II. Circulation 2008;117:1717-1731. 49. Noordegraaf AV, Galie N. The role of the right ventricle in pulmonary arterial hypertension. Eur Respir Rev 2011;20:243-253. 50. Gan CTJ, Lankhaar JW, Marcus JT, et al. Impaired left ventricular filling due to right-to-left ventricular interaction in patients with pulmonary arterial hypertension. American Journal of Physiology-Heart and Circulatory Physiology 2006;290:H1528-H1533. 51. D'Alonzo GE, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension. Ann Intern Med 1991;115:343-349. Chapter 2 1. Guglielmini C, Diana A, Pietra M, et al. Use of the vertebral heart score in coughing dogs with chronic degenerative mitral valve disease. J Vet Med Sci 2009;71:9-13. 2. Singh M, Johnson L, Kittleson M, et al. Bronchomalacia in Dogs with Myxomatous Mitral Valve Degeneration. J Vet Intern Med 2012;26:312-319. 3. Borgarelli M, Buchanan JW. Historical review, epidemiology and natural history of degenerative mitral valve disease. J Vet Cardiol 2012;14:93-101. 4. Detweiler DK, Patterson DF. The prevalence and types of cardiovascular disease in dogs. Ann N Y Acad Sci 1965;127:481-516. 5. Gouni V, Serres FJ, Pouchelon JL, et al. Quantification of mitral valve regurgitation in dogs with degenerative mitral valve disease by use of the proximal isovelocity surface area method. J Am Vet Med Assoc 2007;231:399-406. 6. Kittleson MD, Brown WA. Regurgitant fraction measured by using the proximal isovelocity surface area method in dogs with chronic myxomatous mitral valve disease. J Vet Intern Med 2003;17:84-88. 7. Serres FJ, Chetboul V, Tissier R, et al. Doppler echocardiography–derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001–2005). J Am Vet Med Assoc 2006;229:1772-1778. 8. Chiavegato D, Borgarelli M, D'Agnolo G, et al. Pulmonary hypertension in dogs with mitral regurgitation attributable to myxomatous valve disease. Vet Radiol Ultrasound 2009;50:253-258. 9. Carlsson C, Haggstrom J, Eriksson A, et al. Size and Shape of Right Heart Chambers in Mitral Valve Regurgitation in Small-Breed Dogs. J Vet Intern Med 2009;23:1007-1013. 10. Lord P, Hansson K, Kvart C, et al. Rate of change of heart size before congestive heart failure in dogs with mitral regurgitation. J Small Anim Pract 2010;51:210-218. 11. Atkins C, Bonagura J, Ettinger S, et al. Guidelines for the diagnosis and treatment of canine chronic valvular heart disease. J Vet Intern Med 2009;23:1142-1150. 12. Johnson L. Tracheal collapse. Diagnosis and medical and surgical treatment. Vet Clin North Am Small Anim Pract 2000;30:1253-1266. 13. Dallman M, McClure R, Brown E. Normal and collapsed trachea in the dog: scanning electron microscopy study. Am J Vet Res 1985;46:2110-2115. 14. Dallman M, McClure R, Brown E. Histochemical study of normal and collapsed tracheas in dogs. Am J Vet Res 1988;49:2117-2125. 15. Dabanoğlu I, Ocal M, Kara M. A quantitative study on the trachea of the dog. Anat Histol Embryol 2001;30:57-59. 16. Johnson L, Pollard R. Tracheal collapse and bronchomalacia in dogs: 58 cases (7/2001–1/2008). J Vet Intern Med 2010;24:298-305. 17. Carden KA, Boiselle PM, Waltz DA, et al. Tracheomalacia and tracheobronchomalacia in children and adults. Chest 2005;127:984-1005. 18. Tangner C, Hobson H. A retrospective study of 20 surgically managed cases of collapsed trachea. Vet Surg 1982;11:146-149. 19. Macready DM, Johnson LR, Pollard RE. Fluoroscopic and radiographic evaluation of tracheal collapse in dogs: 62 cases (2001–2006). J Am Vet Med Assoc 2007;230:1870-1876. 20. Harvey C, Fink E. Tracheal diameter: analysis of radiographic measurements in brachycephalic and nonbrachycephalic dogs. J Am Anim Hosp Assoc 1982;18:570-576. 21. Hammond G, Geary M, Coleman E, et al. Radiographic measurements of the trachea in domestic shorthair and Persian cats. J Feline Med Surg 2011;13:881-884. 22. Olsen LH, Haggstrom J, Petersen HD. Acquired valvular heart disease. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and the Cat, 7 ed. St. Louis: Saunders; 2010:1299-1319. 23. Le Roux A, Rademacher N, Saelinger C, et al. Value of tracheal bifurcation angle measurement as a radiographic sign of left atrial enlargement in dogs. Vet Radiol Ultrasound 2012;53:28-33. 24. Dailey ME, O'Laughlin MP, Smith RJH. Airway compression secondary to left atrial enlargement and increased pulmonary artery pressure. Int J Pediatr Otorhinolaryngol 1990;19:33-44. 25. Johnson L, Boon J, Orton EC. Clinical characteristics of 53 dogs with Doppler-derived evidence of pulmonary hypertension: 1992–1996. J Vet Intern Med 1999;13:440-447. 26. Pyle RL, Abbott J, MacLean H. Pulmonary hypertension and cardiovascular sequelae in 54 dogs. Intern J Appl Res Vet Med 2004;2:99-109. 27. Buchanan J, Bucheler J. Vertebral scale system to measure canine heart size in radiographs. J Am Vet Med Assoc 1995;206:194-199. 28. Alavi SM, Keats TE, O'Brien WM. The angle of tracheal bifurcation: its normal mensuration. Am J Roentgenol 1970;108:546-549. 29. 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Hansson K, Haggstrom J, Kvart C, et al. Reader performance in radiographic diagnosis of signs of mitral regurgitation in cavalier King Charles spaniels. J Small Anim Pract 2009;50:44-53. 36. Eom K, Moon K, Seong Y, et al. Ultrasonographic evaluation of tracheal collapse in dogs. J Vet Sci 2008;9:401-405. 37. Poteet BA. Radiology of the heart. In: Tilley LP, Smith FWJ, Oyama MA, Sleeper MM, eds. Manual of Canine and Feline Cardiology, 4 ed. St. Louis: Saunders; 2008:24-48. 38. Adamama-Moraitou KK, Pardali D, Day MJ, et al. Canine bronchomalacia: A clinicopathological study of 18 cases diagnosed by endoscopy. Vet J 2012;191:261-266. 39. De Lorenzi D, Bertoncello D, Drigo M. Bronchial abnormalities found in a consecutive series of 40 brachycephalic dogs. J Am Vet Med Assoc 2009;235:835-840. Chapter 3 1. Serres FJ, Chetboul V, Tissier R, et al. Doppler echocardiography–derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001–2005). J Am Vet Med Assoc 2006;229:1772-1778. 2. Voelkel NF, Quaife RA, Leinwand LA, et al. Right ventricular function and failure. Circulation 2006;114:1883-1891. 3. Kellihan HB, Stepien RL. Pulmonary hypertension in canine degenerative mitral valve disease. J Vet Cardiol 2012;14:149-164. 4. Guglielmini C, Civitella C, Diana A, et al. Serum cardiac troponin I concentration in dogs with precapillary and postcapillary pulmonary hypertension. J Vet Intern Med 2010;24:145-152. 5. Steele JL, Henik RA. Pulmonary hypertension. In: King LG, ed. Textbook of Respiratory Disease in Dogs and Cats, 1 ed. St. Louis: Saunders; 2004:498-507. 6. Johnson L, Boon J, Orton EC. Clinical characteristics of 53 dogs with Doppler-derived evidence of pulmonary hypertension: 1992–1996. J Vet Intern Med 1999;13:440-447. 7. Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 2009;30:2493-2537. 8. Glaus T, Soldati G, Ehrensperger F, et al. Clinical and pathological characterisation of primary pulmonary hypertension in a dog. Vet Rec 2004;154:786-789. 9. Nakamura K, Yamasaki M, Ohta H, et al. Effects of sildenafil citrate on five dogs with Eisenmenger’s syndrome. J Small Anim Pract 2011;52:595-598. 10. Schober KE, Baade H. Doppler Echocardiographic Prediction of Pulmonary Hypertension in West Highland White Terriers with Chronic Pulmonary Disease. J Vet Intern Med 2006;20:912-920. 11. Glaus TM, Tomsa K, Hassig M, et al. Echocardiographic changes induced by moderate to marked hypobaric hypoxia in dogs. Vet Radiol Ultrasound 2004;45:233-237. 12. Kitagawa H, Sasaki Y, Ishihara K, et al. Contribution of live heartworms harboring in pulmonary arteries to pulmonary hypertension in dogs with dirofilariasis. Jpn J Vet Sci 1990;52:1211-1217. 13. Kitagawa H, Sasaki Y, Ishihara K, et al. Cardiopulmonary function values before and after heartworm removal in dogs with caval syndrome. Am J Vet Res 1991;52:126-132. 14. Sasaki Y, Kitagawa H, Hirano Y. Relationship between pulmonary arterial pressure and lesions in the pulmonary arteries and parenchyma, and cardiac valves in canine dirofilariasis. J Vet Med Sci 1992;54:739-744. 15. Pyle RL, Abbott J, MacLean H. Pulmonary hypertension and cardiovascular sequelae in 54 dogs. Intern J Appl Res Vet Med 2004;2:99-109. 16. Delgado JF, Conde E, Sanchez V, et al. Pulmonary vascular remodeling in pulmonary hypertension due to chronic heart failure. Eur J Heart Fail 2005;7:1011-1016. 17. Noordegraaf AV, Galie N. The role of the right ventricle in pulmonary arterial hypertension. Eur Respir Rev 2011;20:243-253. 18. Haddad F, Doyle R, Murphy DJ, et al. Right ventricular function in cardiovascular disease, part II. Circulation 2008;117:1717-1731. 19. Berger M, Haimowitz A, Van Tosh A, et al. Quantitative assessment of pulmonary hypertension in patients with tricuspid regurgitation using continuous wave Doppler ultrasound. J Am Coll Cardiol 1985;6:359-365. 20. Serres F, Chetboul V, Gouni V, et al. Diagnostic Value of Echo-Doppler and Tissue Doppler Imaging in Dogs with Pulmonary Arterial Hypertension. J Vet Intern Med 2007;21:1280-1289. 21. Chiavegato D, Borgarelli M, D'Agnolo G, et al. Pulmonary hypertension in dogs with mitral regurgitation attributable to myxomatous valve disease. Vet Radiol Ultrasound 2009;50:253-258. 22. Buchanan J, Bucheler J. Vertebral scale system to measure canine heart size in radiographs. J Am Vet Med Assoc 1995;206:194-199. 23. Le Roux A, Rademacher N, Saelinger C, et al. Value of tracheal bifurcation angle measurement as a radiographic sign of left atrial enlargement in dogs. Vet Radiol Ultrasound 2012;53:28-33. 24. Jurcut R, Giusca S, La Gerche A, et al. The echocardiographic assessment of the right ventricle: what to do in 2010? Eur J Echocardiogr 2010;11:81-96. 25. Habib G, Torbicki A. The role of echocardiography in the diagnosis and management of patients with pulmonary hypertension. Eur Respir Rev 2010;19:288-299. 26. Rudski LG, Lai WW, Afilalo J, et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010;23:685-713. 27. Roberts JD, Forfia PR. Diagnosis and assessment of pulmonary vascular disease by Doppler echocardiography. Pulm Circ 2011;1:160-181. 28. Schwarzwald CC, Schober KE, Bonagura JD. Methods and reliability of echocardiographic assessment of left atrial size and mechanical function in horses. Am J Vet Res 2007;68:735-747. 29. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic curve. Radiology 1982;743:29-36. 30. Onyango EM. Electrocardiography may be a useful tool in the diagnosis of early mild canine heartworm disease. Acta Vet Brno 2011;80:081-085. 31. Detweiler DK, Patterson DF. The prevalence and types of cardiovascular disease in dogs. Ann N Y Acad Sci 1965;127:481-516. 32. Sisson D, Schaeffer D. Changes in linear dimensions of the heart, relative to body weight, as measured by M-mode echocardiography in growing dogs. Am J Vet Res 1991;52:1591-1596. 33. Morrison SA, Moise NS, Scarlett J, et al. Effect of Breed and Body Weight on Echocardiographic Values in Four Breeds of Dogs of Differing Somatotype. J Vet Intern Med 1992;6:220-224. 34. Kellum HB, Stepien RL. Sildenafil Citrate Therapy in 22 Dogs with Pulmonary Hypertension. J Vet Intern Med 2007;21:1258-1264. 35. Wu CC, Fan PC. Prevalence of canine dirofilariasis in Taiwan. J Helminthol 2003;77:83-88. 36. Liang S, Huang H, Wong S, et al. Prevalence of canine dirofilariasis in pet dogs from Taipei area. J Chin Soc Vet Sci 1996;22:167-174. 37. Gomberg-Maitland M, Thenappan T, Ryan JJ, et al. Cor Pulmonale. 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The functional anatomy of ventricular contraction. Circ Res 1953;1:162-170. 44. Kaul S, Tei C, Hopkins JM, et al. Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J 1984;107:526-531. 45. Forfia PR, Fisher MR, Mathai SC, et al. Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med 2006;174:1034-1041. 46. Sasaki Y, Kitagawa H, Ishihara K, et al. Improvement in pulmonary arterial lesions after heartworm removal using flexible alligator forceps. Jpn J Vet Sci 1990;52:743-752. 47. Grapsa J, Gibbs JSR, Dawson D, et al. Morphologic and Functional Remodeling of the Right Ventricle in Pulmonary Hypertension by Real Time Three Dimensional Echocardiography. Am J Cardiol 2012;109:906-913. 48. Chin KM, Rubin LJ. Pulmonary arterial hypertension. J Am Coll Cardiol 2008;51:1527-1538. 49. Dong SJ, Smith ER, Tyberg JV. Changes in the radius of curvature of the ventricular septum at end diastole during pulmonary arterial and aortic constrictions in the dog. Circulation 1992;86:1280-1290. 50. Stool EW, Mullins CB, Leshin SJ, et al. Dimensional changes of the left ventricle during acute pulmonary arterial hypertension in dogs. Am J Cardiol 1974;33:868-875. 51. Louie EK, Rich S, Levitsky S, et al. Doppler echocardiographic demonstration of the differential effects of right ventricular pressure and volume overload on left ventricular geometry and filling. J Am Coll Cardiol 1992;19:84-90. 52. Ryan T, Petrovic O, Dillon JC, et al. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 1985;5:918-924. 53. Marcus JT, Gan C, Zwanenburg JJM, et al. Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. J Am Coll Cardiol 2008;51:750-757. 54. DeMadron E, Bonagura J, O'Grady M. Normal and paradoxical ventricular septal motion in the dog. Am J Vet Res 1985;46:1832-1841. 55. Fisher MR, Forfia PR, Chamera E, et al. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 2009;179:615-621. Chapter 4 1. Sisson DD. Pathophsiology of heart failure. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and the Cat, 7 ed. St. Louis: Saunders; 2010:1143-1158. 2. Mahmud E, Raisinghani A, Hassankhani A, et al. Correlation of left ventricular diastolic filling characteristics with right ventricular overload and pulmonary artery pressure in chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol 2002;40:318-324. 3. Gan CTJ, Lankhaar JW, Marcus JT, et al. Impaired left ventricular filling due to right-to-left ventricular interaction in patients with pulmonary arterial hypertension. American Journal of Physiology-Heart and Circulatory Physiology 2006;290:H1528-H1533. 4. MacNee W, Maclay J, McAllister D. Cardiovascular injury and repair in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5:824-833. 5. Falk JA, Kadiev S, Criner GJ, et al. Cardiac disease in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5:543-548. 6. Gehlbach BK, Geppert E. The Pulmonary Manifestations of Left Heart Failure. Chest 2004;125:669-682. 7. Olsen LH, Haggstrom J, Petersen HD. Acquired valvular heart disease. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine: Diseases of the Dog and the Cat, 7 ed. St. Louis: Saunders; 2010:1299-1319. 8. Dailey ME, O'Laughlin MP, Smith RJH. Airway compression secondary to left atrial enlargement and increased pulmonary artery pressure. Int J Pediatr Otorhinolaryngol 1990;19:33-44. 9. Chaliki HP, Hurrell DG, Nishimura RA, et al. Pulmonary venous pressure: relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs. Catheter Cardiovasc Interv 2002;56:432-438. 10. Kellihan HB, Stepien RL. Pulmonary hypertension in canine degenerative mitral valve disease. J Vet Cardiol 2012;14:149-164. 11. Serres F, Chetboul V, Gouni V, et al. Diagnostic Value of Echo-Doppler and Tissue Doppler Imaging in Dogs with Pulmonary Arterial Hypertension. J Vet Intern Med 2007;21:1280-1289. 12. Guglielmini C, Civitella C, Diana A, et al. Serum cardiac troponin I concentration in dogs with precapillary and postcapillary pulmonary hypertension. J Vet Intern Med 2010;24:145-152. 13. Johnson L, Boon J, Orton EC. Clinical characteristics of 53 dogs with Doppler-derived evidence of pulmonary hypertension: 1992–1996. J Vet Intern Med 1999;13:440-447. 14. Sasaki Y, Kitagawa H, Hirano Y. Relationship between pulmonary arterial pressure and lesions in the pulmonary arteries and parenchyma, and cardiac valves in canine dirofilariasis. J Vet Med Sci 1992;54:739-744. 15. Dong SJ, Smith ER, Tyberg JV. Changes in the radius of curvature of the ventricular septum at end diastole during pulmonary arterial and aortic constrictions in the dog. Circulation 1992;86:1280-1290. 16. Santamore WP, Dell'Italia LJ. Ventricular interdependence: Significant left ventricular contributions to right ventricular systolic function. Prog Cardiovasc Dis 1998;40:289-308. 17. Pyle RL, Abbott J, MacLean H. Pulmonary hypertension and cardiovascular sequelae in 54 dogs. Intern J Appl Res Vet Med 2004;2:99-109. 18. Schober KE, Baade H. Doppler Echocardiographic Prediction of Pulmonary Hypertension in West Highland White Terriers with Chronic Pulmonary Disease. J Vet Intern Med 2006;20:912-920. 19. Serres FJ, Chetboul V, Tissier R, et al. Doppler echocardiography–derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001–2005). J Am Vet Med Assoc 2006;229:1772-1778. 20. Carlsson C, Haggstrom J, Eriksson A, et al. Size and Shape of Right Heart Chambers in Mitral Valve Regurgitation in Small-Breed Dogs. J Vet Intern Med 2009;23:1007-1013. 21. DeMadron E, Bonagura J, O'Grady M. Normal and paradoxical ventricular septal motion in the dog. Am J Vet Res 1985;46:1832-1841. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/6550 | - |
| dc.description.abstract | 呼吸系統與左右心之間複雜的交互作用，可能導致心肺疾病有較高合併發生的機率。在呼吸系統疾病下造成心臟功能與結構改變的致病機轉可能來自於肺循環血流動力學的改變與血管床重塑，另外慢性炎症反應和缺氧也可能是誘發的原因之一。左右心間高度的依存關係來自於共同擁有的心室間隔、心包囊與結構上交錯的肌纖維，而這樣密切的交互作用在右心與左心衰竭的關係上可能扮演重要的角色。本論文包含兩個部分，第一項研究包含了五十四隻無心肺症狀的健康犬隻與一百三十三隻按照紐約心臟協會分級系統修正版 (modified New York heart association functional classification) 分組的退化性二尖瓣疾病犬，透過統計胸腔放射線數位影像上從氣管到支氣管共六個部位的氣管徑與入胸處寬度比例與左右主要之氣管交叉處的夾角在不同心衰竭分級犬隻上的差異去了解氣管與支氣管塌陷和退化性二尖瓣疾病的關係。結果顯示氣管塌陷與退化性二尖瓣疾病的發生並無直接相關性，也無法證明氣管塌陷是心衰竭的危險因子之一，而氣管與支氣管僅在心臟解剖學相關位置受到壓迫，且壓迫程度與心衰竭程度相關。第二項研究中使用心臟超音波測量四十隻健康無心肺症狀犬隻與其他分別因呼吸道疾病、犬心絲蟲病與退化性二尖瓣心臟病而提升肺動脈壓力的一百六十九隻病犬，以超音波測得右心參數來評估不同病因導致的肺高壓對於右心功能之影響。結果顯示不同病因導致的肺高壓可能會造成不同程度的右心塑形，其中以心絲蟲與呼吸道疾病導致之肺動脈高壓對肺動脈與右心結構上的影響程度較為顯著。而在這三種造成肺動脈高壓的疾病間，左右心交互作用的差異可能來自於心絲蟲，呼吸道疾病以及退化性二尖瓣疾病間左右心狀態與壓力上的不同。 | zh_TW |
| dc.description.abstract | The complex interactions among respiratory system, right and left heart may lead to the high comorbidity between the cardiorespiratory diseases. The hemodynamic alteration and vascular bed remodeling of the pulmonary circulation, systemic inflammation and hypoxia are the possible pathogenesis of cardiac functional and structural changes in respiratory system disorders. Ventricular interdependence mediated through interventricular septum, pericardium sac and transmitted myofibers may play an important role in the relationship of right and left heart failure. The ratio of tracheobronchial diameters to thoracic inlet distance and the angle of tracheal bifurcation on thoracic radiographs were estimated to investigate the relationship between chronic degenerative mitral valvular disease (CDMD) and tracheobronchial collapse in 54 clinically healthy small breed dogs and 79 dogs with CDMD at different conditions of modified New York heart association functional classification. The result indicated that narrowing of trachea and bronchus in dogs with CDMD developed where the anatomical regions directly contacted with the heart and the degree of tracheobronchial compression was associated with severity of CDMD. However, the study failed to identify that trachea collapse is one of the risk factors for development CDMD and left heart failure. In the second study, the echocardiographic right indices were measured in 40 clinically healthy dogs and 169 dogs with different causes of elevated pulmonary artery pressure. The result presented that right heart indices were affected differently by chronic respiratory disorders, heartworm disease and moderate to severe CDMD; chronic respiratory disorders and heartworm disease had significant effect on the deformation of the pulmonary vascular and right ventricle. The different ventricular interdependence among the three causes of elevated pulmonary artery pressure might be attributed to the interaction between the dilated right ventricle and the different conditions of left ventricle. | en |
| dc.description.provenance | Made available in DSpace on 2021-05-17T09:14:36Z (GMT). No. of bitstreams: 1 ntu-101-R98643006-1.pdf: 1593255 bytes, checksum: 94a3de8fb9654190eb74e1d0fd5cfe73 (MD5) Previous issue date: 2012 | en |
| dc.description.tableofcontents | 口試委員會審定書 i
Acknowledgement ii Abstract iii 中文摘要 iv Table of Contents v List of Tables vi List of Figures viii Chapter 1 1 General Introduction 1 References: 8 Chapter 2 13 Luminal Diameters of Trachea and Bronchi in Small Breed Dogs with and without Chronic Degenerative Mitral Valvular Disease 13 References: 26 Chapter 3 35 Echocardiographic Assessment of Right Heart Indices in Dogs with Elevated Pulmonary Artery Pressure associated with Chronic Respiratory Disorders, Heartworm Disease and Chronic Degenerative Mitral Valvular Disease 35 Reference 53 Chapter 4 68 Summarized Discussion 68 | |
| dc.language.iso | en | |
| dc.title | 評估犬隻呼吸道與慢性心臟疾病相關性之研究 | zh_TW |
| dc.title | Evaluation of the Relationship between Canine Respiratory Disorders and Chronic Heart Disease | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 100-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 吳應寧(Ying-Ling Wu),林荀龍(Shiun-Long Lin) | |
| dc.subject.keyword | 退化性二尖瓣心臟病,氣管塌陷,肺動脈壓力,心絲蟲,呼吸道疾病,右心參數,犬隻, | zh_TW |
| dc.subject.keyword | chronic degenerative mitral valvular disease,tracheobronchial collapse,elevated pulmonary artery pressure,heartworm disease,chronic respiratory disorders,right heart indices,dog, | en |
| dc.relation.page | 73 | |
| dc.rights.note | 同意授權(全球公開) | |
| dc.date.accepted | 2012-08-15 | |
| dc.contributor.author-college | 獸醫專業學院 | zh_TW |
| dc.contributor.author-dept | 臨床動物醫學研究所 | zh_TW |
| Appears in Collections: | 臨床動物醫學研究所 | |
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| File | Size | Format | |
|---|---|---|---|
| ntu-101-1.pdf | 1.56 MB | Adobe PDF | View/Open |
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