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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 邵耀華(Yio Wha Shau) | |
| dc.contributor.author | Chang Hsiang Huang | en |
| dc.contributor.author | 黃章翔 | zh_TW |
| dc.date.accessioned | 2021-06-16T23:09:30Z | - |
| dc.date.available | 2013-08-16 | |
| dc.date.copyright | 2012-08-16 | |
| dc.date.issued | 2012 | |
| dc.date.submitted | 2012-08-03 | |
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Quemada, Rheology of concentrated disperse system III, General features of proposed non-Newtonian model. Comparison with experimentaldata, Rheological Acta 17 (1978) 643–653. [28] Hoskins PR. Simulation and validation of arterial ultrasound imaging and blood flow. Ultrasound Med Biol. 2008 May;34(5):693-717. [29] Lowe GD, Lee AJ, Rumley A, Price JF, Fowkes FG. Blood viscosity and risk of cardiovascular events: the Edinburgh Artery Study. Br J Haematol. 1997 Jan;96(1):168-73. [30] Carine Guivier-Curien, ValerieDeplano, EricBertrand, JeanDominiqueSingland, FabienKoskas. Analysis of blood flow behaviour in custom stent grafts. Journal of Biomechanics 42 (2009) 1754-61. [31] J. R. Womersley. Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J Physiol. 1955 March 28; 127(3): 553-563. [32] Mills CJ, Gabe IT, Gault JH, Mason DT, et al. Pressure-flow relationships and vascular impedance in man. Cardiovasc Res. 1970 Oct;4(4):405-17. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/64944 | - |
| dc.description.abstract | 腹部主動脈瘤成因乃為動脈血管壁病變導致血管彈性疲乏，血管像氣球般向外膨脹隆起，嚴重時血管破裂，病患因出血而死亡。目前主流治療腹部主動脈血管肌瘤的方法為內套膜支架治療法，將血管支架植入血管內以阻隔病變血管來達到治療的效果。
腹部主動脈血管瘤的大小、形狀、彎曲度因人而異，而目前市售的支架主要由主體和兩側腸骨動脈所組成，支架的尺寸並無一定的標準，只要達到治療的效果其支架主體的長度可長可短。內套膜支架治療法術後其中的兩項併發症狀為： 1. 支架中形成血栓和支體栓塞。 2. 支架位移。 本研究針對上述兩項併發症狀，利用電腦模擬不同主體長度的血管支架在置入腹部主動脈瘤後其支架中的流場，進而分析主體長度的長短對支架中流場的影響，期望能找出最佳的支架尺寸設計以減少支架中血栓發生的機率和支架位移發生的情形。由模擬的結果可得到在血流減速時迴流與渦流容易形成於主體下游處而形成血栓使得支架支體栓塞，而主體長度越長的支架越容易有迴流與渦流的發生。而造成支架位移的拖力則與支架主體長度無關。 | zh_TW |
| dc.description.abstract | Abdominal aortic aneurysm (AAA) is a balloon-like bulge in an abdominal artery that may be caused by infection or congenital weakening of the connective tissue component bring about artery wall elasticity fatigue. In severe aneurysm rupture, the patient died due to bleeding .At present the mainstream treatment of AAA is Endovascular aneurysm repair (EVAR), the stent graft implantation into AAA sac and blocking lesion to achieve therapeutic effect.
The size, geometry and curvature of AAA is different from person to person. The current commercially endograft is composed of main body and iliac leg. The geometry of the stent does not have a certain standard. As long as it achieve therapeutic effect, the length of main body can be longer or shorter. The two Complications of EVAR is including： 1. Intraprosthetic thrombosis and endograft limb obstruction. 2. Device migration. This study,In response to these Complications, Analyze the Influence Of Endograft with different main body length On Blood Hemodynamic In AAA by CFD. Expect to find the best geometry design to reduce Intraprosthetic thrombosis and Device migration occurred.The results show that when blood flow deceleration, recirculation and vortex is easily formed in the downstream of main body leading to Intraprosthetic thrombosis and endograft limb obstruction. The longer length of main body, it is more easily formed. And the drag force making Device migration has nothing to do with the main body length. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-16T23:09:30Z (GMT). No. of bitstreams: 1 ntu-101-R99543080-1.pdf: 6432201 bytes, checksum: f84581a628bdfec0596b7e73d3d4045d (MD5) Previous issue date: 2012 | en |
| dc.description.tableofcontents | 誌謝 .................................................... I
中文摘要 ................................................ II 英文摘要 ............................................... III 目錄 ................................................... IV 圖表目錄 ................................................ V 第一章 導論 ............................................ 1 1-1 前言 ............................................... 1 1-2 內套膜支架治療法 ..................................... 4 1-3 文獻回顧 ............................................ 8 1-4 研究目的 ........................................... 13 第二章 血液動力學 ...................................... 14 2-1 血液流動原理 ........................................ 14 2-2 分離流、迴流、渦流與渦度 ............................. 17 2-3 拖曳力 ............................................ 20 第三章 研究方法 ....................................... 21 3-1 有限元素模型 ....................................... 21 3-2 血液性質 .......................................... 24 3-3 邊界條件 .......................................... 24 3-4 評估標準 .......................................... 25 第四章 結果與討論 ..................................... 27 4-1 支架內血液的速度場與流線圖 ........................... 27 4-2 支架內的拖曳力 ..................................... 46 4-3 討論 ............................................. 48 第五章 結論與未來展望 .................................. 55 5-1 結論 ............................................. 55 5-2 未來展望 .......................................... 56 參考文獻 ............................................... 57 | |
| dc.language.iso | zh-TW | |
| dc.title | 分析置入腹部主動脈瘤中不同尺寸的血管支架對血液動力學的影響 | zh_TW |
| dc.title | Analysis Of the Influence Of Endograft Geometry On Blood Hemodynamic In Abdominal Aortic Aneurysm | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 100-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 吳毅暉(I Hui Wu) | |
| dc.contributor.oralexamcommittee | 王崇禮,朱錦洲 | |
| dc.subject.keyword | 腹部主動脈瘤,內套膜支架治療法,血栓,栓塞,支架位移,渦流,拖曳力, | zh_TW |
| dc.subject.keyword | Abdominal aortic aneurys,Endovascular aneurysm repair,Thrombosis,Obstruction,Device migration,Vortex,Drag force, | en |
| dc.relation.page | 60 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2012-08-06 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 應用力學研究所 | zh_TW |
| 顯示於系所單位： | 應用力學研究所 | |
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