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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 吳應寧(Ying-Ling Wu) | |
dc.contributor.author | Hung-Chih Chou | en |
dc.contributor.author | 周宏致 | zh_TW |
dc.date.accessioned | 2021-06-16T23:00:31Z | - |
dc.date.available | 2013-08-10 | |
dc.date.copyright | 2012-08-10 | |
dc.date.issued | 2012 | |
dc.date.submitted | 2012-08-07 | |
dc.identifier.citation | [1] 林嘉勇。臺灣馬匹日本腦炎流行病學調查。國立臺灣大學臨床動物醫學研究所碩士論文,台北,17-18,2011。
[2] 張詠樂。臺灣地區馬病毒性疾病之血清學檢測。國立臺灣大學獸醫學研究所碩士論文,台北,9-15,2001。 [3] Ainsworth DM, Cheetham J. Disorders of the respiratory system. In: Reed SM, ed. Equine internal medicine. 3rd ed. Saunders Elsevier, USA, 311-313, 2010. [4] Both GW, Sleigh MJ, Cox N, Kendal AP. Antigenie drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes at key antigenic sites. Virology 48: 52-60, 1983. [5] Buonagurio DA, Nakada S, Parvin JD, Krystal M, Palese P, Fitch WM. Evolution of human influenza A viruses over 50 years: rapid, uniform rate of change in NS gene. Science 232: 980-982, 1986. [6] Britton AP, Robinson JH. Isolation of influenza A virus from a 7-day-old foal with bronchointerstitial pneumonia. Can Vet J 43: 55, 2002. [7] Chan KY, Wang CH, Wu YL. Serological survey of equine Piroplasmosis, equine granulocytic Anaplasmosis, and equine Lyme disease in Taiwan. Taiwan Vet J 36: 261-267, 2010. [8] Chapman PS, Green C, Main JPM, Taylor PM, Cunningham FM, Cook AJC, Marr CM. Retrospective study of the relationships between age, inflammation and the isolation of bacteria from the lower respiratory tract of thoroughbred horses. Veterinary Record 146: 91-95, 2000. [9] Crawford PC, Dubovi EJ, Castleman WL, Stephenson I, Gibbs EPJ, Chen L, Smith C, Hill RC, Ferro P, Pompey J, Bright RA, Medina MJ, Johnson CM, Olsen CW, Cox NJ, Klimov AI, Katz JM, Donis RO. Transmission of equine influenza virus to dogs. Science 310: 482, 2005. [10] Fang R, Min JW, Huylebroeck D, Devos R, Fiers W. Complete structure of A/Duck/Ukraine/63 influenza hemagglutinin gene: animal virus as progenitor of human H3 Hong Kong 1968 influenza hemagglutinin. Cell 25: 315–323, 1981. [11] Gorman OT, Bean WJ, Kawaoka Y, Webster RG. Evolution of the nucleoprotein gene of influenza A virus. Virology 64: 1487-1497, 1990. [12] Guo Y, Wang M, Kawaoka Y, Gorman O, Ito T, Saito T, Webster RG. Characterization of a new avian-like influenza A virus from horses in China. Virology 188: 245-255, 1992. [13] Hannant D, Mumford JA, Jessett DM. Duration of circulating antibody and immunity following infection with equine influenza virus. Veterinary Record 122: 125-128, 1988. [14] Hinshaw VS, Webster RG. The natural history of influenza A viruses. In: Beare AS, ed. Basic and applied influenza research. 1st ed. CRC, Florida, 79, 1982. [15] Kawaoka Y, Bean WJ, Webster RG. Evolution of the hemagglutinin of equine H3 influenza viruses. Virology 169: 283-292, 1989. [16] Kida H, Kawaoka Y, Naeve CW, Webster RG. Antigenic and genetic conservation of H3 influenza virus in wild ducks. Virology 159: 109-119, 1987. [17] Kida H, Shortridge KF, Webster RG. Origin of the hemagglutinin gene of H3N2 influenza viruses from pigs in China. Virology 162: 160-166, 1988. [18] Livesay GJ, Neill TO, Hannant D, Yadav MP, Mumford JA. The outbreak of equine influenza (H3N8) in the United Kingdom in 1989: diagnostic use of an antigen capture ELISA. Veterinary Record 133: 515-519, 1993. [19] Morley PS, Townsend HG, Bogdan JR, Haines DM. Descriptive epidemiologic study of disease associated with influenza virus infections during three epidemics in horses. J Am Vet Med Assoc 216: 535, 2000. [20] Mumford EL, Traub-Dargatz JL, Salman MD, Collins JK, Getzy DM, Carman J. Monitoring and detection of acute viral respiratory tract disease in horses. J Am Vet Med Assoc 213: 385-390, 1998. [21] Nakajima S, Takeuchi Y, Nakajima K. Location of the evolutionary tree of influenza H3 haemagglutinin genes of Japanese strains isolated during 1985-6 season. Epidemiol Infect 100: 301-310, 1988. [22] Nelson KM, Schram BR, McGregor MW, Sheoran AS, Olsen CW, Lunn DP. Local and systemic isotype-specific antibody responses to equine influenza virus infection versus conventional vaccination. Vaccine 16: 1306-1313, 1998. [23] Paillot R, Hannant D, Kydd JH, Daly JM. Vaccination against equine influenza: quid novi? Vaccine 24: 4047, 2006. [24] Peek SF, Landolt G, Karasin AI. Acute respiratory distress syndrome and fetal interstitial pneumonia associated with equine influenza in a neonatal foal. J Vet Intern Med 18: 132, 2004. [25] Quinlivan M, Zamarin D, Sastre AG, Cullinane A, Chambers T, Palese P. Attenuation of equine influenza viruses through truncations of the NS1 protein. Virology 79: 8431–8439, 2005. [26] Scholtissek C, Rohde W, Von HV, Rott R. On the origin of the human influenza virus subtypes H2N2 and H3N2. Virology 87: 13-20, 1978. [27] Wood J, Smith KC, Daly JM, Newton RJ. Viral infections of the equine respiratory tract. In: McGorum BC, ed. Equine respiratory medicine and surgery. 1st ed. Saunders Elsevier, China, 287-297, 2007. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/64825 | - |
dc.description.abstract | 馬流行性感冒(Equine Influenza, EI)為高接觸之傳染性疾病。馬流感病毒為正黏液病毒科(Orthomyxoviridae)之A型流行感冒病毒(Influenzavirus A),可感染所有年齡層之馬匹,其中以年輕馬較易感染。然而近十年內臺灣地區並無馬流行性感冒之流行病學調查。為了解臺灣馬匹馬流行性感冒之現況,於2010年5月至10月分別於臺灣北部(台北、桃園)、中部(新竹、苗栗、台中)、南部(高雄、屏東)和東部(花蓮、台東),採集全臺馬場217匹馬之頸靜脈血液樣本,對馬流行性感冒病毒抗體進行酵素連結免疫吸收分析(enzyme-linked immunosorbent assay, ELISA)血清學檢測。結果顯示217個樣本的陽性率約為47%(103/217),其中大部分的陽性馬場集中於北部、中部和南部。希望藉此建立臺灣馬流行性感冒之流行病學最新資料,並依據結果進行防疫策略之規劃與防治技術之研究與改進。 | zh_TW |
dc.description.abstract | Equine influenza (EI) is an acute, highly contagious disease worldwide. The EI virus belongs to the influenza virus A class of the Orthomyxoviridae family. Horses of all ages are susceptible to EI, especially foals. However, no epidemiologic evaluations of EI in Taiwan have been conducted within the past 10 years. To describe the current epidemiology of EI among horses in Taiwan, 217 samples of equine serum were collected from horses from 23 horse fields in 4 different regions of Taiwan between May and October 2010, i.e., the northern region (Taipei and Taoyuan), the central region (Hsinchu, Miaoli, and Taichung), the southern region (Kaohsiung and Pingtung), and the eastern region (Hualien and Taitung). Samples were tested by enzyme-linked immunosorbent assay (ELISA). Overall, approximately 47% (103/217) of samples were seropositive for EI. In addition, the high prevalence of EI was seen in horse fields concentrated in northern, central, and southern regions of Taiwan. We used statistical methods to analyze the seroprevalance of EI in Taiwan and assess our ELISA results. Future research should focus on delineating the epidemiology of EI. Furthermore, measures to prevent EI outbreaks should be designed and promptly implemented. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T23:00:31Z (GMT). No. of bitstreams: 1 ntu-101-R99643015-1.pdf: 2555161 bytes, checksum: 176cac9cf2b014b2ca231c5561298d38 (MD5) Previous issue date: 2012 | en |
dc.description.tableofcontents | 口試委員會審定書 #
誌謝 i 中文摘要 ii ABSTRACT iii CONTENTS iv LIST OF TABLES vi Chapter 1 Introduction 1 Chapter 2 Literature Review 3 2.1 Etiology 3 2.2 Epidemiology 3 2.3 Clinical Signs 4 2.4 Diagnosis 5 2.5 Treatment 5 2.6 Prevention 6 2.7 Potential Risk 7 2.7.1 Evolution of H3 Subtype of Influenza A Viruses 7 2.7.2 Cross-species Infection 7 2.7.3 Cases of Cross-species Infection 8 Chapter 3 Material and Methods 10 3.1 Sample Size and Selection of Horses 10 3.2 Blood Samples 11 3.3 Putative Risk Factors 11 3.4 Equine Influenza ELISA 11 3.4.1 General Information 11 3.4.2 Descriptions and Principle 12 3.4.3 Instruments 12 3.4.4 Preparation of Sample and Wash Solution 13 3.4.5 Procedure of ELISA 13 3.5 Statistical Analyses 14 Chapter 4 Results 15 Chapter 5 Discussion and Conclusion 20 REFERENCES 23 APPENDIX 26 | |
dc.language.iso | en | |
dc.title | 2010年臺灣馬匹馬流行性感冒之血清盛行率調查 | zh_TW |
dc.title | Seroprevalence of Equine Influenza in Horses in Taiwan in 2010 | en |
dc.type | Thesis | |
dc.date.schoolyear | 100-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 季昭華(Chao-Hua Chi),王金和(Ching-Ho Wang) | |
dc.subject.keyword | 流行病學,馬流行性感冒,馬, | zh_TW |
dc.subject.keyword | Epidemiology,Equine Influenza,Horse, | en |
dc.relation.page | 52 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2012-08-07 | |
dc.contributor.author-college | 獸醫專業學院 | zh_TW |
dc.contributor.author-dept | 臨床動物醫學研究所 | zh_TW |
顯示於系所單位: | 臨床動物醫學研究所 |
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