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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 詹長權(Chang-Chuan Chan) | |
dc.contributor.author | Yen-Jou Lin | en |
dc.contributor.author | 林燕柔 | zh_TW |
dc.date.accessioned | 2021-06-16T17:26:57Z | - |
dc.date.available | 2022-08-15 | |
dc.date.copyright | 2012-09-17 | |
dc.date.issued | 2012 | |
dc.date.submitted | 2012-08-16 | |
dc.identifier.citation | 1. 台灣電力公司, http://www.taipower.com.tw/.
2. Bohm MC: Capture-ready power plants-Options, technologies and economics. 2006. 3. Rubin ES, Kalagnanam JR, Frey HC, Berkenpas MB: Integrated environmental control modeling of coal-fired power systems. J Air Waste Manage 1997, 47(11):1180-1188. 4. 行政院環保署: 空氣品質模式支援中心,國內全國性排放清冊(Taiwan Emission Data System, TEDS)7.1版之2007年固定污染源排放量推估資料, http://ivy2.epa.gov.tw/air-ei/Default.asp. 5. 經濟部工業局: 台灣工業用地供給與服務資訊網, http://idbpark.moeaidb.gov.tw/index.asp. 6. Brunekreef B, Holgate ST: Air pollution and health. Lancet 2002, 360(9341):1233-1242. 7. Wang XH, Bi XH, Sheng GY, Fu JM: Chemical composition and sources of PM10 and PM2.5 aerosols in Guangzhou, China. Environ Monit Assess 2006, 119(1-3):425-439. 8. Riedl MA: The effect of air pollution on asthma and allergy. Curr Allergy Asthm R 2008, 8(2):139-146. 9. Rosenlund M, Forastiere F, Porta D, De Sario M, Badaloni C, Perucci CA: Traffic-related air pollution in relation to respiratory symptoms, allergic sensitisation and lung function in schoolchildren. Thorax 2009, 64(7):573-580. 10. USEPA: Integrated science assessment for particulate matter (Final Report). EPA/600/R-08/139F 2009:1-2228. 11. Querol X, Viana M, Alastuey A, Amato F, Moreno T, Castillo S, Pey J, de la Rosa J, de la Campa AS, Artinano B et al: Source origin of trace elements in PM from regional background, urban and industrial sites of Spain. Atmos Environ 2007, 41(34):7219-7231. 12. LungUSA: Toxic Air: The Case for Cleaning Up Coal-fired Power Plants. American Lung Association 2011. 13. Cheng CM, Hack P, Chu P, Chang YN, Lin TY, Ko CS, Chiang PH, He CC, Lai YM, Pan WP: Partitioning of Mercury, Arsenic, Selenium, Boron, and Chloride in a Full-Scale Coal Combustion Process Equipped with Selective Catalytic Reduction, Electrostatic Precipitation, and Flue Gas Desulfurization Systems. Energ Fuel 2009, 23:4805-4816. 14. Huggins F, Goodarzi F: Environmental assessment of elements and polyaromatic hydrocarbons emitted from a Canadian coal-fired power plant. Int J Coal Geol 2009, 77(3-4):282-288. 15. Meij R, Winkel HT: The emissions of heavy metals and persistent organic pollutants from modern coal-fired power stations. Atmos Environ 2007, 41(40):9262-9272. 16. Nordberg GF, Fowler B.A., Nordberg M., Friberg L.T.: Handbook on the toxicology of metals Boston: Academic Press 2007. 17. IARC: Arsenic and arsenic compounds. Iarc Monographs on the Evaluation of Carcinogenic Risks to Humans 2004, 84:41-93. 18. ATSDR: Public Health Statement: Arsenic. Division of Toxicology and Environmental Medicine 2007:1-10. 19. Chang MJ, Walker K, McDaniel RL, Connell CT: Impaction collection and slurry sampling for the determination of arsenic, cadmium, and lead in sidestream cigarette smoke by inductively coupled plasma-mass spectrometry. J Environ Monitor 2005, 7(12):1349-1354. 20. IARC: Mercury and Mercury Compounds. Iarc Monographs on the Evaluation of Carcinogenic Risks to Humans 1993, 58:239. 21. Zahir F, Rizwi SJ, Haq SK, Khan RH: Low dose mercury toxicity and human health. Environ Toxicol Phar 2005, 20(2):351-360. 22. Liu J, Zheng BS, Aposhian HV, Zhou YS, Chen ML, Zhang AH, Waalkes MP: Chronic arsenic poisoning from burning high-arsenic-containing coal in Guizhou, China. Environ Health Persp 2002, 110(2):119-122. 23. Ranft U, Miskovic P, Pesch B, Jakubis P, Fabianova E, Keegan T, Hergemoller A, Jakubis M, Nieuwenhuijsen MJ, Grp ES: Association between arsenic exposure from a coal-burning power plant and urinary arsenic concentrations in Prievidza District, Slovakia. Environ Health Persp 2003, 111(7):889-894. 24. Wilhelm M, Pesch B, Wittsiepe R, Jakubis P, Miskovic P, Keegan T, Nieuwenhuijsen MJ, Ranft U: Comparison of arsenic levels fingernails with urinary As species as biomarkers of arsenic exposure in residents living close to a coal-burning power plant in Prievidza District, Slovakia. J Expo Anal Env Epid 2005, 15(1):89-98. 25. Chiang WF, Yang HJ, Lung SCC, Huang S, Chiu CY, Liu IL, Tsai CL, Kuo CY: A comparison of elementary schoolchildren's exposure to arsenic and lead. J Environ Sci Heal C 2008, 26(3):237-255. 26. Chen CY, Yu HW, Zhao JJ, Li B, Qu LY, Liu SP, Zhang PQ, Chai ZF: The roles of serum selenium and selenoproteins on mercury toxicity in environmental and occupational exposure. Environ Health Persp 2006, 114(2):297-301. 27. 行政院環保署: 固定污染源管制,有害空氣污染物. 2012. 28. Jayasekher T: Aerosols near by a coal fired thermal power plant: chemical composition and toxic evaluation. Chemosphere 2009, 75(11):1525-1530. 29. Agrawal P, Mittal A, Prakash R, Kumar M, Singh TB, Tripathi SK: Assessment of Contamination of Soil due to Heavy Metals around Coal Fired Thermal Power Plants at Singrauli Region of India. B Environ Contam Tox 2010, 85(2):219-223. 30. Ghosh S, Chatterjee T, Saha T, Mukherjee A: Genotoxicity assessment of soil contamination: a case study from Farakka coal-fired power plant in eastern India. THE NUCLEUS 2012, 55:45-50. 31. Hu SW, Chan YJ, Hsu HT, Wu KY, ChangChien GP, Shie RH, Chan CC: Urinary levels of 1-hydroxypyrene in children residing near a coal-fired power plant. Environ Res 2011, 111(8):1185-1191. 32. 內政部: 內政部戶政司全球資訊網, http://www.ris.gov.tw/zh_TW/web/guest. 33. WHO: World Health Organization, Biological Monitoring of Chemical Exposure in the Workplace. Vol 1. 1996. 34. 陳家揚: 液相層析/質譜儀的基質效應與因應之道. CHEMISTRY (The Chinese Chemical Society, Taipei) 2007, 65(2):151-155. 35. TEPA: 行政院環保署環境檢驗所, 空氣中粒狀污染物金屬檢測方法, 感應耦合電漿質譜儀 (NIEA A305.10C). 2009. 36. TEPA: 行政院環保署環境檢驗所, 環境檢驗檢量線製備及查核指引 (NIEA-PA103). In.; 2004. 37. TEPA: 行政院環保署環境檢驗所, 環境檢驗方法偵測極限測定指引 (NIEA-PA107). 2004. 38. TEPA: 行政院環保署環境檢驗所, 水中金屬及微量元素檢測方法—感應耦合電漿質譜法 (NIEA-W313.51B). 2009. 39. TEPA: 行政院環保署環境檢驗所, 環境檢驗品管分析執行指引 (NIEA-PA104). 2004. 40. 行政院環保署, 空氣品質監測網 http://taqm.epa.gov.tw/taqm/zh-tw/default.aspx. 41. Lakes Environmental, Wind Rose Plots for Meteorological Data http://www.weblakes.com/products/wrplot/index.html. 42. 台灣颱風資訊中心, http://typhoon.ws/. 43. ESRI: Environmental System Research Institute, Inc., ArcGIS 10, http://www.esri.com/software/arcgis/arcgis-for-desktop/free-trial.html. 44. 交通部運輸研究所: 交通路網數值地圖, http://www.iot.gov.tw/ct.asp?xItem=154948&ctNode=1091. 45. 內政部國土測繪中心: 通用版電子地圖查詢圖台, http://emap.nlsc.gov.tw/gis/. 46. 中部某鋼鐵廠: http://www.dragonsteel.com.tw/default.htm. 47. Lee RE, Crist HL, Riley AE, MacLeod KE: Concentration and size of trace metal emission from a power plant, a steel plant, and cotton gin. Environmental Science and Technology 1975, 9(7):623-647. 48. Dimitrova SV: Metal sorption on blast-furnace slag. Water Res 1996, 30(1):228-232. 49. 賴順安, 李文智: 鋼鐵廠煙道排放多環芳香烴化合物及金屬元素之特徵. 國立成功大學環境工程學系碩士論文 1999. 50. 經濟部工業局: http://www.moeaidb.gov.tw/. 51. Basha CA, Bhadrinarayana NS, Anantharaman N, Begum KMMS: Heavy metal removal from copper smelting effluent using electrochemical cylindrical flow reactor. J Hazard Mater 2008, 152(1):71-78. 52. Basta NT, McGowen SL: Evaluation of chemical immobilization treatments for reducing heavy metal transport in a smelter-contaminated soil. Environ Pollut 2004, 127(1):73-82. 53. Navas-Acien A, Umans JG, Howard BV, Goessler W, Francesconi KA, Crainiceanu CM, Silbergeld EK, Guallar E: Urine arsenic concentrations and species excretion patterns in American Indian communities over a 10-year period: the Strong Heart Study. Environ Health Perspect 2009, 117(9):1428-1433. 54. Hsueh YM, Huang YL, Huang CC, Wu WL, Chen HM, Yang MH, Lue LC, Chen CJ: Urinary levels of inorganic and organic arsenic metabolites among residents in an arseniasis-hyperendemic area in Taiwan. J Toxicol Env Heal A 1998, 54(6):431-444. 55. 古伯文, 孫建峰, 吳竹蘭, 甯孝真: 重金屬毒物尿液篩檢 財團法人長庚紀念醫院林口醫學中心臨床病理科 2004:1-2. 56. Stankovic S, Jovic M: Health risks of heavy metals in the mediterranean mussels as seafood. Environ Chem Lett 2012, 10(2):119-130. 57. Yenisoy-Karakas S, Tuncel SG: Geographic patterns of elemental deposition in the Aegean region of Turkey indicated by the lichen, Xanthoria parietina (L.) Th. Fr. Sci Total Environ 2004, 329(1-3):43-60. 58. Kim Y, Lee BK: Association between urinary arsenic and diabetes mellitus in the Korean general population according to KNHANES 2008. Sci Total Environ 2011, 409(19):4054-4062. 59. Castano A, Sanchez-Rodriguez JE, Canas A, Esteban M, Navarro C, Rodriguez-Garcia AC, Arribas M, Diaz G, Jimenez-Guerrero JA: Mercury, lead and cadmium levels in the urine of 170 Spanish adults: A pilot human biomonitoring study. Int J Hyg Envir Heal 2012, 215(2):191-195. 60. McKelvey W, Jeffery N, Clark N, Kass D, Parsons PJ: Population-Based Inorganic Mercury Biomonitoring and the Identification of Skin Care Products as a Source of Exposure in New York City. Environ Health Persp 2011, 119(2):203-209. 61. Seiwert M, Conrad A, Becker K, Hunken A, Schulz C, Kolossa-Gehring M: The German Environmental Survey for Children (GerES IV): Socio-Economic Status and Exposure to Pollutants. Epidemiology 2008, 19(6):S250-S250. 62. Brulle RJ, Pellow DN: Environmental justice: Human health and environmental inequalities. Annu Rev Publ Health 2006, 27:103-124. 63. 邊瑋緒, 詹長權: 六輕離島工業區周界之懸浮微粒及附近居民尿中As、Hg濃度之評估研究. 國立台灣大學職業醫學與工業衛生研究所碩士論文 2011. 64. 林右翎, 詹長權: 火力發電廠周界空氣微粒與兒童尿中As、Hg濃度之評估研究. 國立台灣大學職業醫學與工業衛生研究所碩士論文 2010. 65. Lee KH, Chung EK, Moon JS, Nam SW, Lee MY, Son BS: Assessment of human biomonitoring and DNA microarray analysis in the vicinity population on an industrial complex. Mol Cell Toxicol 2011, 7(3):207-219. 66. Querol X, Alastuey A, Rodriguez S, Plana F, Ruiz CR, Cots N, Massague G, Puig O: PM 10 and PM2.5 source apportionment in the Barcelona Metropolitan area, Catalonia, Spain. Atmos Environ 2001, 35(36):6407-6419. 67. Kulshrestha A, Satsangi PG, Masih J, Taneja A: Metal concentration of PM2.5 and PM10 particles and seasonal variations in urban and rural environment of Agra, India. Sci Total Environ 2009, 407(24):6196-6204. 68. USEPA: National Ambient Air Quality Standards (NAAQS). http://wwwepagov/air/criteriahtml, 2006. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/64024 | - |
dc.description.abstract | 背景:根據國內外文獻指出,燃煤火力發電廠會排放大量之砷、汞污染物,並且附著在懸浮微粒上,直接或間接危害人體健康。在台灣之電力供應逾兩成仰賴台中燃煤火力發電廠,伴隨之污染物排放量亦高,但這些污染物對附近居民之暴露狀況的研究仍然有限。本研究之目的係針對燃煤火力發電廠排放之砷及汞,評估與電廠不同距離周邊居民尿中砷、汞濃度之差異並探討其與空氣濃度之關係。
方法:本研究以台中燃煤火力發電廠為主,根據距離及上下風定義高(HE)、低暴露區(LE),分別為五公里內之鄰近社區HE1、下風處社區HE2和五公里外之上風處社區LE2;隨機選取273位20-65歲之社區居民,以問卷調查方式收集居民的個人資料、與金屬暴露相關因子;並收集兩次尿液樣本(2009年與2011年),以感應耦合電漿質譜儀(ICP-MS)測定尿中砷、汞濃度。此外亦利用Harvard Impactor進行高、低暴露區空氣懸浮微粒PM10和PM2.5採樣,PM10中之砷濃度則同樣透過ICP-MS分析。所取得之資料先採用Student’s t test、ANOVA、ANCOVA來判斷生物偵測和環境偵測在區域間之差別,另以複迴歸模式來探討在進一步控制干擾因子之後,區域間是否仍然有差異。 結果:本研究所選取之273位居民中男性有125位、女性有148位;平均年齡為43.55±12.64歲;平均居住年數為28.94±17.13年;有83位在HE1、115位在HE2、75位在LE2。這些居民於2011年之尿砷幾何平均濃度分別為HE1:87.35 (2.58) μg/g creatinine、HE2:65.48 (2.28) μg/g creatinine、LE2:57.28 (2.18) μg/g creatinine;尿汞幾何平均濃度則分別為HE1:1.78 (2.16) μg/g creatinine、HE2:1.04 (2.05) μg/g creatinine、LE2:0.88 (2.04) μg/g creatinine。在距離電廠較近區域、年齡較高、居住年數較久和教育程度較低之居民尿中砷濃度有顯著較高之情形;在距離電廠較近區域、女性、年齡較高、教育程度較低、無抽菸、和食用大部分當地生產魚肉之居民尿中汞濃度有顯著較高之情形。經ANCOVA及複迴歸模式校正干擾因子之後,HE1居民之尿中As、Hg濃度仍有顯著高於其他兩社區居民。空氣懸浮微粒採樣結果顯示,受影響風向時高暴露區PM10中之砷濃度顯著高於低暴露區之趨勢,平均濃度分別為。HE1:1.45±0.68 ng/m3、HE2:2.49±0.96 ng/m3、LE2:0.76±0.27 ng/m3。 結論:居住於燃煤火力發電廠半徑五公里內高暴露區居民之尿中砷、汞濃度顯著高於五公里外之低暴露區居民。 | zh_TW |
dc.description.abstract | Background:Previous studies have shown coal-fired power plants emitted arsenic (As) and mercury (Hg) into environment but studies on the extent of human exposures to these pollutants in their surrounding areas are limited. This study aimed to use the biological markers of urine arsenic and mercury to evaluate adult’s exposures to As and Hg living near a big coal-power plant in Taiwan and identify personal and environmental factors associated with the exposures.
Methods:Based on wind direction and distance to a coal-fired power plant, our study areas includes two downwind high exposure areas (HE1 and HE2) within 5 km radius of the power plant, and a upwind low exposure area (LE2) outside the 5 km radius of the power plant. A total of 273 adults, aged 20 to 65 years, were randomly sampled from the HE and LE areas. Personal information and potential metal-related exposure factors were collected by questionnaire. The first morning urine specimen was collected twice form each person in 2009 and 2011, and the levels of urinary As and Hg were determined by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Ambient PM10 and PM2.5 were sampled by Harvard Impactor, and arsenic in PM10 was analyzed by ICP-MS. The bio-monitoring and ambient air sampling data in these different areas were compared by Student’s t test, ANOVA and ANCOVA. Multiple regressions were applied to determine difference in urine As and Hg among areas adjusting for personal factors. Results:Among the 273 adults aged at 43.55±12.64 years that were in this study, there are 125 males and 148 females, and in 83 subjects in HE1, 115 subjects HE2 and 75 subjects in LE2. The geometric means of urinary As were 87.35 (2.58) μg/g creatinine in HE1, 65.48 (2.28) μg/g creatinine in HE2, and 57.28 (2.18) μg/g creatinine in LE2, respectively, for study subjects in 2011. The geometric means of urinary Hg were 1.78 (2.16) μg/g creatinine in HE1, 1.04 (2.05) μg/g creatinine in HE2, and 0.88 (2.04) μg/g creatinine in LE2, respectively. Urinary As and Hg levels in HE1 were significantly higher than those in LE2. Higher urinary As levels were associated with subject’s distance to power plant, age, length of residence, and lack of education. Higher Hg levels were associated with subject’s distance to the power plant, gemder (female), age, lower education, non-smoking status and consumption of local fish. After adjusted for those confounders by ANCOVA and multiple regression, levels of urinary As and Hg in HE1 were still significantly higher than those in HE2 and LE2. The concentrations of As in PM10 were 1.45±0.68 ng/m3 in HE1, 2.49±0.96 ng/m3 in HE2, 0.76±0.27 ng/m3 in LE2, respectively. Conclusion:Adult residents living within 5 km radius of a coal-fired power plant had significantly higher urinary As and Hg concentrations than those living beyond 5 km radius. | en |
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dc.description.tableofcontents | 摘要......I
ABSTRACT......III 目錄......V 圖目錄......VIII 表目錄......IX 第一章、前言......1 1.1 研究背景......1 1.2 文獻回顧......6 1.2.1 懸浮微粒及其健康效應......6 1.2.2 重金屬砷、汞及其健康效應......7 1.2.3 燃煤火力發電廠周邊居民砷、汞暴露之生物偵測......10 1.2.4 燃煤火力發電廠周界砷、汞濃度之環境監測......11 1.3 研究目的......13 第二章、材料與方法......14 2.1 研究設計與架構......14 2.2 燃煤火力發電廠周界成人暴露及基本資料之收集......17 2.2.1 研究對象......17 2.2.2 問卷資料收集......20 2.2.3 尿液檢體收集......20 2.3 尿液中As、Hg濃度之分析......21 2.3.1 儀器設備、實驗耗料與試劑......21 2.3.2 試劑配製-1(分析2009年不含汞之尿液樣本)......22 2.3.3 試劑配製-2(分析2011年含汞之尿液樣本)......23 2.3.4 尿液中As、Hg分析步驟與方法......24 2.3.5 品質保證與品質控制......28 2.4 燃煤火力發電廠周界空氣品質測站之氣象資料分析......30 2.4.1 線西測站與沙鹿測站......30 2.4.2 線西測站與沙鹿測站之歷年盛行風向......30 2.4.3 線西測站與沙鹿測站之座標定位......32 2.5 燃煤火力發電廠周界空氣懸浮微粒採樣與As、Hg分析......36 2.5.1 空氣懸浮微粒採樣時間......36 2.5.2 空氣懸浮微粒採樣地點......36 2.5.3 空氣懸浮微粒採樣時期於研究地區之盛行風向......37 2.5.4 空氣懸浮微粒採樣與微粒中As之濃度分析方法......37 2.6 數據整理及統計分析......38 第三章、研究結果......40 3.1 燃煤火力發電廠周界成人暴露資料......40 3.1.1 居住於燃煤火力發電廠附近三社區居民之基本資料描述......40 3.1.2 居住於燃煤火力發電廠附近三社區居民之尿中As、Hg濃度......44 3.1.3 干擾因子與尿中As、Hg濃度之分布......48 3.1.4 ANCOVA分析尿中As、Hg濃度之結果......54 3.1.5 複迴歸模式分析尿中As、Hg濃度之結果......55 3.2 空氣懸浮微粒採樣與微粒中As之結果......57 3.2.1 空氣懸浮微粒採樣時期之盛行風向......57 3.2.2 空氣懸浮微粒採樣時期於研究地區之受影響風向......60 3.2.3 空氣懸浮微粒採樣濃度及微粒中As濃度之分布......64 第四章、結果討論......66 4.1 居民尿中As、Hg濃度分布之討論......66 4.2 與國內、外尿中As、Hg濃度研究之比較......69 4.3 空氣懸浮微粒採樣結果之討論......71 4.4 空氣微粒中之As及居民尿中As濃度之討論......72 4.5 研究限制......73 第五章、結論與建議......75 參考文獻......76 附錄一、尿液中重金屬分析之ICP-MS上機標準作業程序......81 附錄二、空氣PM採樣工具設備及標準操作流程......87 | |
dc.language.iso | zh-TW | |
dc.title | 燃煤火力發電廠周遭地區成人尿中砷及汞濃度之研究 | zh_TW |
dc.title | Urinary Levels of Arsenic and Mercury in Adults Living near a Coal-fired Power Plant | en |
dc.type | Thesis | |
dc.date.schoolyear | 100-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 黃耀輝(Yaw-Huei Hwang),胡素婉(Suh-Woan Hu),許惠悰(Hui-Tsung Hsu) | |
dc.subject.keyword | 燃煤火力發電廠,尿液砷,尿液汞,PM10,暴露評估, | zh_TW |
dc.subject.keyword | Coal-fired power plant,Urinary arsenic,Urinary mercury,PM10,Exposure assessment, | en |
dc.relation.page | 91 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2012-08-16 | |
dc.contributor.author-college | 公共衛生學院 | zh_TW |
dc.contributor.author-dept | 職業醫學與工業衛生研究所 | zh_TW |
顯示於系所單位: | 職業醫學與工業衛生研究所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
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ntu-101-1.pdf 目前未授權公開取用 | 2.98 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。