Please use this identifier to cite or link to this item:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/63903Full metadata record
| ???org.dspace.app.webui.jsptag.ItemTag.dcfield??? | Value | Language |
|---|---|---|
| dc.contributor.advisor | 王金和 | |
| dc.contributor.author | You-Hsin Lin | en |
| dc.contributor.author | 林祐新 | zh_TW |
| dc.date.accessioned | 2021-06-16T17:22:33Z | - |
| dc.date.available | 2013-08-20 | |
| dc.date.copyright | 2012-08-20 | |
| dc.date.issued | 2012 | |
| dc.date.submitted | 2012-08-16 | |
| dc.identifier.citation | 第六章、參考資料
黃萬居，台灣發生之雞傳染性支氣管炎。台灣畜獸會學報，1: 1-5，1958。 呂榮修，謝快樂，蔡向榮，林地發，李永林。台灣雞傳染性支氣管炎之發生與病毒分離。中華獸醫誌 19: 119-129, 1993。 謝明昌。台灣雞傳染性支氣管炎病毒之分離、病原性測定及H120疫苗保護試驗。國立台灣大學獸醫學研究所碩士論文。1993。 曾正昌。台灣雞傳染性支氣管炎病毒之病毒分離、血清型鑑定及病原性測定。國立台灣大學獸醫學研究所碩士論文。1995。 陳慧文，家禽傳染性支氣管炎病毒之序列分析、血球凝集特性及診斷方法的開發。國立臺灣大學獸醫專業學院獸醫學研究所博士論文，2010。 陳燕佩，家禽傳染性支氣管炎病毒的血清檢測及疫苗開發。國立臺灣大學獸醫專業學院獸醫學研究所碩士論文，2011。 Albassam MA, Winterfield RW, Thacker HL. Comparison of the neuropathogenicity of four strains of infectious bronchitis virus. Avian Dis 30: 468-476 1986. Alkhatib G, Briedis D. High-Level Eucaryotic In Vivo Expression of Biologically Active Measles Virus Hemagglutinin by Using an Adenovirus Type 5 Helper-Free Vector System. J Virol 62(8): 2718-2727, 1988. Andreasen JR Jr, Jackwood MW, Hilt DA. Polymerase chain reaction amplification of the genome of infectious bronchitis virus. Avian Dis 35(1): 216-220, 1991. Armesto M, Evans S, Cavanagh D, Abu-Median A, Keep S, Britton P. A recombinant avian infectious bronchitis virus expressing a heterologous spike gene belonging to the 4/91 serotype. Plos One 6(8): 1-11, 2011. Beach JR, Schalm OW. A filterable viurs, distinct from that of laryngotracheitis, the cause of a respiratory disease of chicks. Poult Sci 15: 199-206, 1936. Beatrice N, Cheman C, Francois K, Lewis S, Jane T, Kid C, Jason K, Isabelle S, Bernadette CC, Nicolas E, Sylvie vdW, Kwok-Yung Y, Ralf A. Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J Gen Virol 86: 1423-1434, 2005. Beaudette ER, Hudson CB. Cultivation of the virus of infectious bronchitis. Poult Sci 15: 199-206,1937. Bingham RW, Madge MH, Tyrrell DA. Haemagglutination by avian infectious bronchitis virus-a coronavirus. J Gen Virol 28(3): 381-390, 1975. Blissard GW, Rohrmann GF. Baculovirus diversity and molecular biology. Annu Rev Entomol 35: 127-55, 1990). Boots AM, Kusters JG, van Noort JM, Zwaagstra KA, Rijke E, van der Zeijst BA, Hensen EJ. Localization of a T-cell epitope within the nucleocapsid protein of avian coronavirus. Immunology 74(1): 8-13, 1991. Broadfoot DI, Pomeroy BS, Smith WM Jr. Effect of infectious bronchitis on egg production. J Am Vet Med Assoc 124(923): 128-130, 1954. Brown AJ, Bracewell CD. Effect of repeated infections of chickens with infectious bronchitis viruses on the specificity of their antibody responses. Vet Rec 122(9): 207-208, 1988. Bushnell LD, Brandly CA. Laryngotracheitis in chicks. Poult Sci 12: 55-60, 1933. Callison SA, Jackwood MW, Hilt DA. Infectious bronchitis virus S2 gene sequence variability may affect S1 subunit specific antibody binding. Virus Genes 19(2): 143-151, 1999. Capua I, Gough RE, Mancini M, Casaccia C, Weiss C. A 'novel' infectious bronchitis strain infecting broiler chickens in Italy. Zentralblatt fur Veterinarmedizin. Reihe B. J Vet med 41(2): 83-89, 1994. Cavanagh D. Structural polypeptides of coronavirus IBV. J Gen Virol 53: 93-103, 1981. Cavanagh D. Coronavirus IBV glycopolypeptides: size of their polypeptide moieties and nature of their oligosaccharides. J Gen Virol 64: 1187-1191. 1983. Cavanagh D. Coronavirus IBV: further evidence that the surface projections are associated with two glycopolypeptides. J Gen Virol 64: 1787-1791. 1983. Cavanagh D. Coronavirus IBV: structural characterization of the spike protein. J Gen Virol 64: 2577-2583, 1983. Cavanagh D. Severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus. Avian Pathol. 32(6): 567-582, 2003. Cavanagh D. Coronaviruses in poultry and other birds. Avian Pathol 34(6): 439-448, 2005. Cavanagh D. Coronavirus avian infectious bronchitis virus. Vet Res 38: 281-297, 2007. Cavanagh D, Davis PJ. Sequence analysis of strains of avian infectious bronchitis coronavirus isolated during the 1960s in the U.K. Arch Virol 130(3-4): 471-476. 1993. Cavanagh D, Davis PJ. Coronavirus IBV: removal of spike glycopolypeptide S1 by urea abolishes infectivity and haemagglutination but not attachment to cells. J Gen Virol 67: 1443-1448, 1986. Cavanagh D, Davis PJ, Cook JK, Li D, Kant A, Koch G. Location of the amino acid differences in the S1 spike glycoprotein subunit of closely related serotypes of infectious bronchitis virus. Avian Pathol 21(1): 33-43, 1992. Cavanagh D, Davis PJ, Darbyshire JH, Peters RW. Coronavirus IBV: virus retaining spike glycopolypeptide S2 but not S1 is unable to induce virus-neutralizing or haemagglutination-inhibiting antibody, or induce chicken tracheal protection. J Gen Virol 67: 1435-1442, 1986. Cavanagh D, Mawdeitt K, Sharma M, Drury SE, Ainsworth HL, Britton P, Gough RE. Detection of a coronavirus from turkey poults in Europe genetically related to infectious bronchitis virus in chicken. Avian Pathol 31: 81-93, 2001. Cavanagh D, Mawdeitt K, Welchman de B, Britton P, Gough RE. Coronavirus from pheasants (Phasianus colchicus) are genetically closely related to coronaviruses of domestic fowl (infectious bronchitis virus) and turkeys. Avian Pathol 31: 81-93, 2002. Cavanagh D, Naqi SA. Infectious bronchitis. In: Saif AM, Fadly YM, McDougald LR, Swayne DE, eds. Diseases of Poultry. Iowa State University Press, Ames, IA, 101-119, 2003. Chang PC, Kuo TY, Chueh LL, Wang CH. Sequencing and analysis of S1 gene of infectious bronchitis viruses isolated in Taiwan. J Chin Soc Vet Sci 24: 179-187, 1998. Chubb RC. The detection of antibody to avian infectious bronchitis virus by use of immunofluorescence with tissue sections of nephritic kidneys. Aust Vet J 63(4): 131-132, 1986. Cook J. Coronaviridae. In: Jordan F, Pattison M, Alexander D, Faragher T, eds. Poultry Diseases 5th ed. WB Saunders, New York, NY, 298–306, 2002. Corse E, Machamer CE. The cytoplasmic tails of infectious bronchitis virus E and M proteins mediate their interaction. Virology 312(1): 25-34, 2003. Crinion RA. Egg quality and production following infectious bronchitis virus exposure at one day old. Poult Sci 51(2): 582-585, 1972. Cumming RB. Infectious avian nephrosis (uraemia) in Australia. Aust Vet J 39: 145-147, 1963. Cumming RB. The control of avian infectious bronchitis/nephrosis in Australia. Aust Vet J 45(4): 200-203, 1969. Cumming RB. Studies on Australian infectious bronchitis virus. IV. Apparent farm-to-farm airborne transmission of infectious bronchitis vims. Avian Dis 14: 191-195, 1970. Cunningham CH, Stuart HO. The effect of certain chemical agents on the virus of infectious bronchitis of chickens. Am J Vet Res 7: 466-469, 1946. Cunningham CH, Stuart HO. Cultivation of the virus of infectious bronchitis of chickens in embryonated chicken eggs. Am J Vet Res 8: 209-212. 1947. Darbyshire JH. A clearance test to assess protection in chickens vaccinated against avian infectious bronchitis virus. Avian Pathol 14: 497-508, 1985. Darbyshire JH, Peters RW. Sequential development of humoral immunity and assessment of protection in chickens following vaccination and challenge with avian infectious bronchitis virus. Res Vet Sci 37(1): 77-86, 1984. Davies HA, Dourmashkin RR, Macnaughton MR. Ribonucleoprotein of avian infectious bronchitis virus. J Gen Virol 53: 67-74, 1981. Davelaar FG, Bos JVD. Ascorbic acid and infectious bronchitis infections in broilers. Avian Pathol 21: 581-589, 1992. Davelaar FG, Kouwenhoven B. Study on the local effect of eye-drop vaccination against infectious bronchitis in 1-day-old chicks with maternal antibodies. Avian Pathol 10:83-90, 1981. de Groot RJ, Luytjes W, Horzinek MC van der Zeist BA, Spaan WJ, Lenstra JA. Evidence for a coiled-coil structure in the spike proteins of coronaviruses. J Mol Biol 196: 963-966, 1987. de Haan CA, Masters PS, Shen X, Weiss S, Rottier PJ. The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology 296(1): 177-189, 2002. De Wit JJ. Detection of infectious bronchitis virus. Avian Pathol. 29(2): 71-93, 2000. Delaplane JP, Stuart HO. The modification of infectious bronchitis virus of chickens as the result of propagation in embryonated chicken eggs. Rhode Island Agric Exp Sta, Bull, 284, 1941. Delmas B, Laude H. Assembly of coronavirus spike protein into trimers and its role in epitope expression. J Virol 64(11): 5367-5375, 1990. El Houadfi M. Isolation of avian infectious bronchitis viruses in Morocco including an enterotropic variant. Vet Record 116: 445, 1985. Engelhard EK, Kam-Morgan LNW, Washburn JO, Volkman LE. The insect tracheal system: a conduit for the systemic spread of Autographa californica M nuclear polyhedrosis virus. Proc Natl Acad Sci USA 91: 3224-3227, 1994. Escutenaire S, Mohamed N, Isaksson M, Thoren P, Klingeborn B, Belak S, Berg M, Blomberg J. SYBR Green real-time reverse transcription-polymerase chain reaction assay for the generic detection of coronaviruses. Arch Virol 152(1): 41-58, 2007. Fabricant J. Studies on the diagnosis of Newcastle disease and infectious bronchitis. IV. The use of the serum neutralization test in the diagnosis of infectious bronchitis. Cornell Vet 41(1): 68-80, 1951. Falcone E, D'Amore E, Di Trani L, Sili A, Tollis M. Rapid diagnosis of avian infectious bronchitis virus by the polymerase chain reaction. J Virol Methods 64(2): 125-130, 1997. Fazakerley JK, Parker SE, Bloom F, Buchmeier MJ. The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. Virology 187(1): 178-188, 1992. Finney PM, Box PG, Holmes HC. Studies with a bivalent infectious bronchitis killed virus vaccine. Avian Pathol 19(3): 435-450. 1990. Flipsen JT, Martens JW, Van Oers MM, Vlak JM and van Lent JW. Passage of Autographa californica nuclear polyhedrosis virus through the midgut epithelium of Spodoptera exigua larvae. Virology 208: 328-335, 1995. Gallagher TM, Buchmeier MJ.. Coronavirus spike proteins in viral entry and pathogenesis. Virology 279(2): 371-374, 2001 Gelb Jr J, Jackwood MW. Infectious bronchitis. In: Swayne DE, Glisson JR, Pearson JE, Reed WM, Jackwood MW, Woolcock PR, eds. A laboratory manual for the isolation and identification of avian pathogens. The American Association of Avian Pathologists, Pennsylvania, 146-149. 2008. Godet M, Grosclaude J, Delmas B, Laude H. Major receptor-binding and neutralization determinants are located within the same domain of the transmissible gastroenteritis virus (coronavirus) spike protein. J Virol 68(12): 8008-8016, 1994. Gombold JL, Hingley ST, Weiss SR. Fusion-defective mutants of mouse hepatitis virus A59 contain a mutation in the spike protein cleavage signal. J Virol 67(8): 4504-4512 1993. Gough RE, Alexander DJ. Comparison of duration of immunity in chickens infected with a live infectious bronchitis vaccine by three different routes. Res Vet Sci 26(3): 329-332, 1979. Gough RE, Cox WJ, Wingler CE, Sharp MW, Spackman D. Isolation and identification of infectious bronchitis virus from pheasants. Vet Rec 138(9): 208-209, 1996. Gough RE, Randall CJ, Dagless M, Alexander DJ, Cox WJ, Pearson D. A 'new' strain of infectious bronchitis virus infecting domestic fowl in Great Britain. Vet Rec 130(22): 493-493, 1992. Guy JS. Turkey coronavirus is more closely related to avian infectious bronchitis virus than to mammalian coronaviruses: a review. Avian Pathol 29(3): 207-212, 2000. Haijema BJ, Volders H, Rottier PJ. Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. J Virol 78(8): 3863-3871, 2004. Hofstad MS. Avian infectious bronchitis. In Hofstad MS, Barnes HJ, Calnek BW, Reid WM, Yoder HW, eds. Diseases of Poultry, 8th ed. Iowa State University Press, Ames, 429-443, 1984. Hu YC. Baculovirus as a highly efficient expression vector in insect and mammalian cells. Acta Pharmacol Sin 26(4): 405-416, 2005. Huang YP, Wang CH. Development of attenuated vaccines from Taiwanese infectious bronchitis virus strains. Vaccine 24(6): 785-791, 2006. Ignjatovic EJ, Ashton F. Detection and differentiation of avian infectious bronchitis viruses using a monoclonal antibody-based ELISA. Avian Pathol 25(4): 721-736, 1996. Ignjatovic J, Galli L. The S1 glycoprotein but not the N or M proteins of avian infectious bronchitis virus induces protection in vaccinated chickens. Arch Virol 138(1): 117-134. 1994. Ignjatovic J, Sapats S. Identification of previously unknown antigenic epitopes on the S and N proteins of avian infectious bronchitis virus. Arch Virol 150(9): 813-1831, 2005. Jackwood MW. Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickens. J Virol Methods 138: 60-65, 2006. Johnson MA, Pooley C, Ignjatovic J, Tyack SG. A recombinant fowl adenovirus expressing the S1 gene of infectious bronchitis virus protects against challenge with infectious bronchitis virus, Vaccine 21:2730–2736, 2003. Jungherr EL, Chomiak TW, Luginbuhl RE. Immunologic differences in strains of infectious bronchitis. Proc 60th Annu Meet US Livestock Sanit Assoc 203-209, 1956. Kant A, Koch G, van Roozelaar DJ, Kusters JG, Poelwijk FA, van der Zeijst BA. Location of antigenic sites defined by neutralizing monoclonal antibodies on the S1 avian infectious bronchitis virus glycopolypeptide. J Gen Virol 73: 591-596, 1992. Kathleen L, Coelingh VW, Murphy BR, Collins PL, Lebacq-Verheyden A, Battey JF. Expression of biologically active and antigenically authentic parainfluenza Type 3 virus hemagglutinin-neuraminidase glycoprotein by a recombinant baculovirus. Virology 160: 465-472, 1987. Kim OJ, Lee DH, Lee CH. Close relationship between SARS-coronavirus and group 2 coronavirus. J Microbiol 44(1): 83-91, 2006. King DJ, Cavanagh D. Infectious bronchitis virus. In: Calnek BW, Barnes HJ, Beard CW, Reid WM, Yoder HW, eds. Diseases of poultry. 9th ed. Iowa state University Press, Ames. 471-484, 1991. Klumperman J, Locker JK, Meijer A, Horzinek MC, Geuze HJ, Rottier PJ. Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding. J Virol 68(10): 6523-6534. 1994. Koch G, Hartog L, Kant A, van Roozelaar DJ. Antigenic domains on the peplomer protein of avian infectious bronchitis virus: correlation with biological functions. J Gen Virol 71: 1929-1935, 1990. Kost TA, Condreay JP, Jarvis DL. Baculovirus as versatile vectors for protein expression in insect and mammalian cells. Nat Biotechnol 23(5): 567-575, 2005. Kuroda K, Hauser C, Rott R, Klenk HD, Doerfler W. Expression of the influenza virus haemagglutinin in insect cells by a baculovirus vector. EMBO J. 5(6): 1359-1365, 1986. Kusters JG, Jager EJ, Niesters HG, van der Zeijst BA. Sequence evidence for RNA recombination in field isolates of avian coronavirus infectious bronchitis virus. Vaccine 8(6): 605-608. 1990. Lai MM. RNA recombination in animal and plant viruses. Microbiol Rev 56(1): 61-79, 1992. Lai MM, Cavanagh D. The molecular biology of coronaviruses. Adv Virus Res 48: 1-10, 1997. Lai MMC, Holmes KV. Coronaviridae: the virus and their replication. In: Knipe DM, Howley PM, eds. Field Virology, 4th ed. Linppincott Williams & Wilkins Publisher, Philadelphia, 1163-1185, 2001. Lai MM, Patton CD, Baric RS, Stohlman SA. Presence of leader sequences in the mRNA of mouse hepatitis virus. J Virol 46(3): 1027-1033. 1983. Lee CW, Hilt DA, Jackwood MW. Typing of field isolates of infectious bronchitis virus based on the sequence of the hypervariable region in the S1 gene. J Vet Diagn Invest 15(4): 344-348, 2003. Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, Ahuja A, Yung MY, Leung CB, To KF, Lui SF, Szeto CC, Chung S, Sung JJ. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348(20): 1986-1994, 2003. Lipscomb ML, Palomares LA, Hernandez V, Ramirez OT, Kompala DS. Effect of production method and gene amplification on the glycosylationpattern of a secreted reporter protein in CHO cells. Biotechnol Prog 21: 40-49, 2005. Lister SA, Beer JV, Gough RE, Holmes RG, Jones JMW, Orton RG. Outbreaks of nephritis in pheasants (Phasianus colchicus) with a possible coronavirus aetiology. Vet Record 117: 612-613, 1985. Liu S, Kong X. A new genotype of nephropathogenic infectious bronchitis virus circulating in vaccinated and non-vaccinated flocks in China. Avian Pathol 33(3): 321-327, 2004. Lomniczi B. Biological properties of avian coronavirus RNA. J Gen Virol 36(3): 531-533, 1977. Lu YS, Shieh HK, Tsai HJ, Lin DF, Lee YL. The incidence and virus islation of infectious bronchitis in chickens in Taiwan. J Chin Soc Vet Sci 19: 119-129. 1993. Luo Z, Weiss SR. Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein. Virology 244(2): 483-494. 1998. Luque T, O’Reilly DR. Generation of baculovirus expression vectors. Mol Biotechnol 13: 153-63, 1999. MacNaughton MR. The genomes of three coronaviruses. FEBS Lett 94(2): 191-194, 1978. Maeda S, Kawai T, Obinata M, Fujiwara H, Horiuchi T, Saeki Y, SatoY , Furusawa M. Production of human α-interferon in silkworm using a baculovirus vector. Nature 315：592-594, 1985. Masters PS. Localization of an RNA-binding domain in the nucleocapsid protein of the coronavirus mouse hepatitis virus. Arch Virol 125(1-4): 141-160, 1992. Miller LK. Baculovirus as gene expression vectors. Annu Rev Microbiol 42 : 177-199, 1988. Mourez T, Vabret A, Han Y, Dina J, Legrand L, Corbet S, Freymuth F. Baculovirus expression of HCoV-OC43 nucleocapsid protein and development of a Western blot assay for detection of human antibodies against HCoV-OC43. J Virol Methods 139(2): 175-180, 2007. Naqi SA. A monoclonal antibody-based immunoperoxidase procedure for rapid detection of infectious bronchitis virus in infected tissues. Avian Dis 34(4): 893-898, 1990. Nagy E, Derbyshire JB, Dobos P, Krell PJ. Cloning and expression of NDV hemagglutinin-neuraminidase cDNA in a baculovirus expression vector system. Virology 176(2): 426-438, 1990. Naqi SA, Karaca K, Bauman B. A monoclonal antibody-based antigen capture enzyme-linked immunosorbent assay for identification of infectious bronchitis virus serotypes. Avian Pathol 22(3): 555-564, 1993. Niesters HGM, Lenstra JA, Spaan W1M, Zijderveld AJ, Bleumink-Pluym NMC, Hong F, Van Scharrenburg GJM, Horzinek MC, van der Zeijst BAM. The peplomer protein sequence of the M41 strain of coronavirus IBV and its comparison with Beaudette strains. Virus Res 5: 253-263, 1986. Okazaki K, Honda E, Kono Y. Expression of bovine herpesvirus 1 glycoprotein gIII by a recombinant baculovirus in insect cells. J Gen Virol 75: 901-904, 1994. Parsons D, Ellis MM, Cavanagh D, Cook JK. Characterisation of an infectious bronchitis virus isolated from vaccinated broiler breeder flocks. Vet Rec 131(18): 408-411, 1992. Possee RD. Cell-surface expression of influenza virus haemagglutinin in insect cells using a baculovirus vector. Virus Res 5(1): 43-59, 1986. Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green K, Tellier R, Draker R, Adachi D, Ayers M, Chan AK, Skowronski DM, Salit I, Simor AE, Slutsky AS, Doyle PW, Krajden M, Petric M, Brunham RC, McGeer AJ. Identification of severe acute respiratory syndrome in Canada. N Engl J Med 348(20): 1995-2005, 2003. Rendic D, Wilson IBH, Paschinger K. The glycosylation capacity of insect cells. Croat Chem Acta 81(1): 7-21, 2008. Riddell C. Avian Histopathology. American Association of American Pathologists, Kennett Square, PA. 1987. Rottier PJ, Welling GW, Welling-Wester S, Niesters HG, Lenstra JA, van der Zeijst BA. Predicted membrane topology of the coronavirus protein E1. Biochemistry (Mosc) 25(6): 1335-1339, 1986. Sawicki SG, Sawicki DL. Coronavirus transcription: subgenomic mouse hepatitis virus replicative intermediates function in RNA synthesis. J Virol 64: 1050-1056, 1990. Schalk AF, Hawn MC. An apparently new respiratory disease of baby chicks. J Am Vet Med Assoc 78: 413-422, 1931. Schochetman G, Stevens RH, Simpson RW. Presence of infectious polyadenylated RNA in coronavirus avian bronchitis virus. Virology 77(2): 772-782, 1977. Schultze B, Cavanagh D, Herrler G. Neuraminidase treatment of avian infectious bronchitis coronavirus reveals a hemagglutinating activity that is dependent on sialic acid-containing receptors on erythrocytes. Virology 189(2): 792-794, 1992. Seah JN, Yu L, Kwang J. Localization of linear B-cell epitopes on infectious bronchitis virus nucleocapsid protein. Vet Microbiol 75(1): 11-16. 2000. Sestak K, Zhou Z, Shoup DI, Saif LJ. Evaluation of the baculovirus-expressed S glycoprotein of transmissible gastroenteritis virus (TGEV) as antigen in a competition ELISA to differentiate porcine respiratory coronavirus from TGEV antibodies in pigs. J Vet Diagn Invest 11(3): 205-214, 1999. Shi Q. Genetic relationships of infectious bronchitis virus isolates from Mississippi broilers. Avian Dis 44:66, 2000. Shieh CK, Soe LH, Makino S, Chang MF, Stohlman SA, Lai MM. The 5'-end sequence of the murine coronavirus genome: implications for multiple fusion sites in leader-primed transcription. Virology 156(2): 321-330. 1987. Siddell S, Wege H, ter Meulen V. The structure and replication of coronaviruses. Curr Top Microbiol Immunol 99: 131-163, 1982. Smith GE, Summers MD, Fraser MJ. Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol Cell Biol 3: 2156-2165, 1983. Song CS, Lee YJ, Lee CW, Sung HW, Kim JH, Mo IP, Izumiya Y, Jang HK, Mikami T. Induction of protective immunity in chickens vaccinated with infectious bronchitis virus S1 glycoprotein expressed by a recombinant baculovirus. J Gen Virol 79: 719–723, 1998. Spaan W, Cavanagh D, Horzinek MC. Coronaviruses: structure and genome expression. J Gen Virol 69: 2939-2952, 1988. Stern DF, Sefton BM. Coronavirus proteins: structure and function of the oligosaccharides of the avian infectious bronchitis virus glycoproteins. J Virol 44(3): 804-812, 1982. Sturman LS, Holmes KV, Behnke J. Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid. J Virol 33(1): 449-462: 1980. Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M, Lam WK, Seto WH, Yam LY, Cheung TM, Wong PC, Lam B, Ip MS, Chan J, Yuen KY, Lai KN, A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348(20):77-1985. 2003. Tomley FM, Mockett AP, Boursnell ME, Binns MM, Cook JK, Brown TD, Smith GL. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. J Gen Virol 68: 2291-2298, 1987. Tweeten KA, Bulla LA, Consigli RA. Characterization of an extremely basic protein derived from granulpsis virus nucleocapsids. J Virol 33: 866-876, 1980. van Eck JH. Effects of experimental infection of fowl with EDS'76 virus, infectious bronchitis virus and/or fowl adenovirus on laying performance. Vet Q 5(1): 11-25, 1983. Van Roekel H, Clarke MK, Bullis KL, Olesiuk OM, Sperling FG. Infectious bronchitis. Am J Vet Res 12(43): 140-146, 1951. Vennema H, Godeke GJ, Rossen JW, Voorhout WF, Horzinek MC, Opstelten DJ, Rottier PJ. Nucleocapsid-independent assembly of coronavirus-like particles by co-expression of viral envelope protein genes. EMBO J 15(8): 2020-2028, 1996. Wang CH, Hong CC, Seak JC. An ELISA for antibodies against infectious bronchitis virus using an S1 spike polypeptide. Vet Microbiol 85(4): 333-342, 2002. Wang K, Kathleen M, Holtz M, Anderson K, Chubet R, Mahmoud W, Cox MMJ. Expression and purification of an influenza hemagglutinin—one step closer to a recombinant protein-based influenza vaccine. Vaccine 24(12): 2176-2185, 2006. Wang CH, Tsai CT. Genetic grouping for the isolates of avian infectious bronchitis virus in Taiwan. Arch Virol 141(9): 1677-1688, 1996. Williams AK, Wang L, Sneed LW, Collisson EW. Comparative analyses of the nucleocapsid genes of several strains of infectious bronchitis virus and other coronaviruses. Virus Res 25(3): 213-222, 1992. Winterfield RW, Hitchner SB. Etiology of an infectious nephritis-nephrosis syndrome of chickens. Am J Vet Res 23: 1273–1279, 1962. Worthington KJ, Currie RJ, Jones RC. A reverse transcriptase-polymerase chain reaction survey of infectious bronchitis virus genotypes in Western Europe from 2002 to 2006. Avian Pathol 37(3): 247-257, 2008. Yang T, Wang HN, Wang X, Tang JN, Gao R, Li J, Guo ZC, Li YL. Multivalent DNA vaccine enhanced protection efficacy against infectious bronchitis virus in chickens. J Vet Med Sci 71(12): 1585-1590. 2009. Yu L, Liu W, Schnitzlein WM, Tripathy DN, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Dis 45(2): 340-348, 2001. Zhou ML, Williams AK, Chung SI, Wang L, Collisson EW. Infectious bronchitis virus nucleocapsid protein binds RNA sequences in the 3′ terminus of the genome. Virology 217:191–199, 1996. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/63903 | - |
| dc.description.abstract | 中文摘要
於台灣所分離到的家禽傳染性支氣管炎病毒毒株當中也有數個毒株經過神經胺酸酶的處理後會表現出血球凝集 (Hemagglutination, HA)的特性。其中一台灣一型家禽傳染性支氣管炎病毒2575-5在經過神經胺酸酶處理過後會表現出血球凝集的特性，但該毒株之減毒株在神經胺酸酶處理後則不會表現出血球凝集的特性，為瞭解此血球凝集特性之改變，本實驗將減毒株之S1蛋白基因進行選殖，另將2575-5的S1蛋白基因進行點突變，並將此點突變與選殖之產物放入pFastBacHT A質體中，接著利用同源重組將在pFastBacHT A內的S1醣蛋白轉移至bacmid上並轉染Sf-9細胞產生重組之桿狀病毒，以桿狀病毒蛋白表現系統進行表現蛋白，經過繼代三代後以蔗糖梯度離心純化重組之病毒之後進行血球凝集與血球吸附試驗，經由此實驗可以表現出所欲研究之S1蛋白並且將兩者進行比較來了解該蛋白上之特定胺基酸改變是否與其血液凝集特性改變有關，且可瞭解所表現之蛋白是否與傳染性支氣管炎之S1蛋白有相同之生物特性。 | zh_TW |
| dc.description.abstract | Abstract
A Taiwan local infectious bronchitis virus strain 2575 TW-I showed hemagglutination activity after neuraminidase treatment while its attenuated strain did not. In order to investigate this altered hemagglutination activity, we cloned the S1 gene of the attenuated strain. The nucleotide differences between original and attenuated strains were mutated in the S1 gene by site direct mutation. The S1 gene in the pFastBacHT A was transferred to the bacmids in DH10Bac. The Bac-to-Bac baculovirus expressing system was used to express both wild and attenuated strain S1 proteins. After transfection and passages, the P3 stock of recombinant baculovirus was generated and purified by sucrose gradient separation. The hemagglutination (HA) activity and cell-associtaed hemadsorption (Hd) activity of the expression proteins were examined. Both recombinant baculoviruses showed Hd but no HA activities. The Hd activities can be inhibited by anti-IBV antiserum. Through this method, desired S1 protein mutant could be expressed with the baculovirus expressing system and further studied for biological activity and immunological reactivity. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-16T17:22:33Z (GMT). No. of bitstreams: 1 ntu-101-R99629007-1.pdf: 2193949 bytes, checksum: 2d1a8c9f05e489f693fdd8bdc0f8d4f2 (MD5) Previous issue date: 2012 | en |
| dc.description.tableofcontents | 目錄
口試委員審定書……………………………………………………………………...# 致謝……………………………………………………………………………………i 摘要…………………………………………………………………...………………ii Abstract……………………………………………………………………………….iii 目錄…………………………………………………………………………...………iv 表次……………………………………………………………………………….….vii 圖次…………………………………………………………………………..……...viii 第一章 序言…………………………………………………………………………..1 第二章 文獻回顧……………………………………………………………………..3 第一節 歷史背景.................................................................................................3 第二節 病毒分類.................................................................................................4 第三節 病毒之結構與功能............................ ....................................................5 2-3.1 病毒型態.............................................................................................5 2-3.2 病毒結構.............................................................................................6 2-3.2.1 IBV之病毒基因.........................................................................6 2-3.2.2棘突醣蛋白.................................................................................7 2-3.2.3封套蛋白.....................................................................................9 2-3.2.4 基質醣蛋白................................................................................9 2-3.2.5核殼蛋白.....................................................................................9 第四節 病原性與致病機製................................................................................10 2.4.1自然宿主與傳播途徑...................................................................10 2.4.2病毒傳播........................................................................................11 2.4.3病毒複製........................................................................................11 2.4.4臨床症狀與病灶...........................................................................12 第五節 病原鑑定................................................................................................13 2.5.1病毒分離.......................................................................................13 2.5.2抗原捕捉法...................................................................................14 2.5.3核酸診斷.......................................................................................14 第六節 預防與控制............................................................................................15 2.6.1活毒疫苗.......................................................................................16 2.6.2死毒疫苗.......................................................................................17 2.6.3次單位疫苗...................................................................................18 第七節 昆蟲桿狀病毒與桿狀病毒蛋白質表現系統........................................18 第三章 材料與方法....................................................................................................22 3.1 病毒株與細胞株...........................................................................................22 3.2 RNA萃取.......................................................................................................22 3.3增幅台灣一型傳染性支氣管炎病毒2575-75之S1基因...........................23 3.4點突變............................................................................................................23 3.5 傳染性支氣管炎病毒2575-75全段S1基因與點突變質體之選殖..........24 3.6 構築重組bacmid DNA.................................................................................25 3.7 轉染與重組病毒之增殖...............................................................................26 3.8 測定重組病毒力價.......................................................................................26 3.9 純化重組病毒...............................................................................................27 3.10表現重組S1蛋白........................................................................................27 3.11純化重組S1蛋白........................................................................................27 3.12重組病毒與純化後重組蛋白之蛋白質定量..............................................28 3.13以西方墨點法偵測重組S1蛋白................................................................28 3.14以免疫螢光染色法確認重組蛋白之表現..................................................30 3.15以間接型酵素連結免疫吸附試驗 (Indirect ELISA)測定重組蛋白與各型別血清之反應.....................................................................................................31 3.16測定重組蛋白之血球吸附試驗.................................................................31 3.17利用帶有禽流感病毒HA蛋白之腺病毒感染細胞進行之血球吸附試驗.........................................................................................................................32 3.18以各型別之血清針對重組病毒進行血球吸附抑制試驗.........................32 3.19以重組桿狀病毒進行血球凝集抑制試驗.................................................33 3.20重組病毒之血球凝集試驗.........................................................................33 3.21 IBV結構蛋白之醣基去除與血球凝集反應.............................................34 3.22 統計分析....................................................................................................34 第四章 結果 4.1 Bacmid DNA之重組與點突變....................................................................35 4.2重組病毒之構築、定量與純化...................................................................35 4.3重組病毒之表現與純化...............................................................................36 4.4重組S1蛋白與重組桿狀病毒之抗原性.....................................................36 4.5血球凝集試驗與血球吸附試驗...................................................................37 4.6血球吸附與血球凝集抑制試驗...................................................................38 4.7醣基去除對血球凝集之影響.......................................................................39 第五章 討論...............................................................................................................40 第六章 未來展望.......................................................................................................46 第七章參考資料.........................................................................................................47 附錄.............................................................................................................................78 | |
| dc.language.iso | zh-TW | |
| dc.subject | 血球凝集 | zh_TW |
| dc.subject | 傳染性支氣管炎 | zh_TW |
| dc.subject | 血球吸附 | zh_TW |
| dc.subject | Hemadsorption | en |
| dc.subject | Hemagglutination | en |
| dc.subject | Infectious bronchitis virus | en |
| dc.title | 傳染性支氣管炎病毒S1醣蛋白質與血球吸附、血球凝集關係之探討 | zh_TW |
| dc.title | Hemagglutination and hemadsorption activities associated with S1 glycoprotein of infectious bronchitis virus | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 100-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 鄭益謙,闕玲玲,陳秋麟 | |
| dc.subject.keyword | 血球吸附,血球凝集,傳染性支氣管炎, | zh_TW |
| dc.subject.keyword | Hemadsorption,Hemagglutination,Infectious bronchitis virus, | en |
| dc.relation.page | 84 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2012-08-16 | |
| dc.contributor.author-college | 獸醫專業學院 | zh_TW |
| dc.contributor.author-dept | 獸醫學研究所 | zh_TW |
| Appears in Collections: | 獸醫學系 | |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| ntu-101-1.pdf Restricted Access | 2.14 MB | Adobe PDF |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.