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  1. NTU Theses and Dissertations Repository
  2. 電機資訊學院
  3. 生醫電子與資訊學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/62295
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dc.contributor.advisor林啟萬
dc.contributor.authorJian-Hao Panen
dc.contributor.author潘建豪zh_TW
dc.date.accessioned2021-06-16T13:39:19Z-
dc.date.available2020-01-01
dc.date.copyright2013-07-19
dc.date.issued2013
dc.date.submitted2013-07-15
dc.identifier.citation[1] Low back pain. Available: http://www.umm.edu/altmed/articles/low-back-000101.htm
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[8] T.-C. Chen, 'Electrophysiological Study of Pulsed Radiofrequency Treatment in Neuropathic Pain Model and Behavior Study of Long-term Implantation,' National Taiwan University, 2011.
[9] W.-T. Lin, 'The Effect of Waveform Parameters of Implantable Pulsed RadioFrequency Electrical Stimulator for Neuropathic Pain control,' National Taiwan University, 2010.
[10] A. K. RamRakhyani, S. Mirabbasi, and C. Mu, 'Design and Optimization of Resonance-Based Efficient Wireless Power Delivery Systems for Biomedical Implants,' IEEE Transactions on Biomedical Circuits and Systems, vol. 5, pp. 48-63, 2011.
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[12] L. Zhen Ning, R. A. Chinga, T. Ryan, and L. Jenshan, 'Design and Test of a High-Power High-Efficiency Loosely Coupled Planar Wireless Power Transfer System,' Industrial Electronics, IEEE Transactions on, vol. 56, pp. 1801-1812, 2009.
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[18] C.-H. Hsu, S.-B. Tseng, Y.-J. Hsieh, and C.-C. Wang, 'One-Time-Implantable Spinal Cord Stimulation System Prototype,' Biomedical Circuits and Systems, IEEE Transactions on, vol. 5, pp. 490-498, 2011.
[19] H.-W. Chiu, M.-L. Lin, C.-W. Lin, I. H. Ho, W.-T. Lin, P.-H. Fang, et al., 'Pain control on demand based on pulsed radio-frequency stimulation of the dorsal root ganglion using a batteryless implantable CMOS SoC,' Biomedical Circuits and Systems, IEEE Transactions on, vol. 4, pp. 350-359, 2010.
[20] H. W. Chiu, C. C. Lu, J. M. Chuang, W. T. Lin, C. W. Lin, M. C. Kao, et al., 'A Dual-Mode Highly Efficient Class-E Stimulator Controlled by a Low-Q Class-E Power Amplifier Through Duty Cycle.'
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[25] C.-H. Chang, 'Feasibility study of implantable pulsed-radiofrequency stimulator with verification on sciatica rat model,' Master, Institute of Biomedical Engineering, National Taiwan University, 2009.
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dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/62295-
dc.description.abstract慢性痛是現在人常見的困擾,每年損失龐大的醫療資源成本。Neuromodulation therapies如脊椎神經刺激、周邊神經刺激、腦脊髓膜內給藥系統,是其他常規治療失效時,最後的治療方法。其中植入式脈衝產生器(IPG)是近年廣為應用於治療慢性疼痛的一項技術,該電子裝置輸出低頻刺激訊號於目標神經,干擾疼痛訊號的傳遞,然而,低頻刺激容易造成病人的不適感(paraesthesia),而脈衝式射頻電刺激(PRF)屬於高頻刺激,不會造成病人不適,商用IPG也尚未應用此項技術。
本文提出一具無線供電的可無線軟體定義之脈衝射頻電刺激架構,外部控制器與植入裝置之間以醫療器材無線電頻段403MHz進行通訊,植入裝置從外部控制器接收能量與刺激參數,並且定時回覆狀態與資訊。PRF參數可以輕易由外部控制器的人機介面上更改,包含週期、脈衝寬度、載波頻率、振幅(±5V)皆能夠被設定,系統亦可輸出低頻刺激訊號。
無線電力傳輸的頻率操作於350kHz~450kHz,功率放大器在初始等待植入裝置連接時,只有約170mW功耗,距離15mm植入裝置即可獲得足夠的能量進行通訊,令外部控制器調整輸出能量。效率於10mm的距離可達40%,最大傳輸距離約為20mm。
為了讓系統成為高可靠性的植入式醫療器材,除了植入裝置有除顫保護,系統亦自行偵測錯誤,外部控制器監控功率放大器的供應電流及溫度、植入裝置監控整流電壓及溫度,當錯誤發生時,外部控制器停止傳能給植入裝置,避免系統失效,甚至危害人體組織。
zh_TW
dc.description.provenanceMade available in DSpace on 2021-06-16T13:39:19Z (GMT). No. of bitstreams: 1
ntu-102-R00945007-1.pdf: 6889379 bytes, checksum: 7034b680db133ce7998ce85d64f299ab (MD5)
Previous issue date: 2013
en
dc.description.tableofcontents口試委員審定書.....i
誌謝............ii
摘要...........iii
Abstract.......iv
圖目錄..........ix
表目錄..........xi
第一章緒論 1
1.1 研究背景 1
1.1.1 脈衝射頻電刺激 2
1.1.2 無線電力傳輸 4
1.1.3 相關應用現況 5
1.2 研究目標 7
1.3 全系統概觀 9
第二章刺激單元 11
2.1 簡介 11
2.2 材料 11
2.3 脈衝寬度控制 14
第三章 無線電力傳輸 17
3.1 無線電力系統概觀 17
3.2 材料 18
3.2.1 Wireless Power Transmitter 18
3.2.2 Wireless Power Receiver 19
3.2.3 Current Measurement 20
3.2.4 Thermal Sensing 21
3.2.5 Power Management 22
3.3 共振式電感耦合 23
3.3.1 耦合係數 24
3.3.2 品質因子 24
3.4 Power Delivery Tracking 27
3.5 Class D Power Amplifier 29
3.6 效率分析 31
第四章 軟體流程與韌體設定 39
4.1 State Diagram of Internal Device 39
4.2 Flow Chart of External Controller 40
4.3 CC430 RF Settings 41
4.3.1 Packet Definition 41
4.3.2 RF Parameters 43
第五章 結果與討論 44
5.1 Printed Curcuit Board 44
5.2 Pratical Operation 44
5.3 Output Waveform 48
5.4 Wireless Power Efficiency 52
結論 54
參考資料 55
dc.language.isozh-TW
dc.subject脈衝式射頻電刺激zh_TW
dc.subject無線電力zh_TW
dc.subject植入裝置zh_TW
dc.subjectPulsed-radiofrequencyen
dc.subjectImplantable deviceen
dc.subjectWireless poweren
dc.title具軟體定義無線傳輸介面之植入式脈衝射頻電刺激系統zh_TW
dc.titleAn Implantable Pulsed-Radiofrequency Stimulation System with Software-defined Wireless Interfaceen
dc.typeThesis
dc.date.schoolyear101-2
dc.description.degree碩士
dc.contributor.oralexamcommittee郭義松,施文彬,邱銘章,李柏磊
dc.subject.keyword脈衝式射頻電刺激,植入裝置,無線電力,zh_TW
dc.subject.keywordPulsed-radiofrequency,Implantable device,Wireless power,en
dc.relation.page57
dc.rights.note有償授權
dc.date.accepted2013-07-16
dc.contributor.author-college電機資訊學院zh_TW
dc.contributor.author-dept生醫電子與資訊學研究所zh_TW
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