請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/62280完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 花茂棽(Mau-Sun, Hua) | |
| dc.contributor.author | Yen-Ting Chen | en |
| dc.contributor.author | 陳妍諪 | zh_TW |
| dc.date.accessioned | 2021-06-16T13:38:22Z | - |
| dc.date.available | 2016-06-30 | |
| dc.date.copyright | 2013-07-25 | |
| dc.date.issued | 2013 | |
| dc.date.submitted | 2013-07-16 | |
| dc.identifier.citation | Chinese References
王瑋瀚、花茂棽、楊啓正、朱怡娟、鄭婷文、葉炳強 (2008)。 台灣WAIS-Ⅲ中文版算術、記憶廣度測驗及其組合估算工作記憶指數在臨床上之適用性：回溯性研究。「中華心理學刊」，50，187-199。﹝Wei-Han Wang, Mau-Sun Hua, Chi-Cheng Yang, Yi-Chuan Chu, Ting-Wen Cheng, & Ping-Keung Yip. (2008). The clinical applicability of the arithmetic, digit span subtests of the Taiwan WAIS-Ⅲ, and their composite in reflecting the working memory index: A retrospective study, Chinese Journal of Psychology, 50, 187-199.﹞ 陳榮華、陳心怡 (2002)。「魏氏成人智力量表第三版(中文版)指導手冊」。台北：中國行為科學社。﹝Chen H. Y. & Chen R. H. (2002). Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) Manual for Taiwan. Taipei, Taiwan: The Chinese Behavioral Science Corporation﹞ 彭鍾伃 (2009)。「台大數字奇偶序列測驗：台灣北部區域常模與信度效度研究」(未出版之碩士論文)。臺灣大學，台北市。﹝Chung-Yu Peng. (2009). The National Taiwan University Odd-Even Number Sequencing Test (TOENS): North Taiwan normative data and reliability and validity study (Unpublished master’s thesis). National Taiwan University, Taipei, Taiwan. English References Andreasen, N. C., OLeary, D. S., Cizadlo, T., Arndt, S., Rezai, K., Ponto, L. L. B., … Hichwa, R. D. (1996). Schizophrenia and cognitive dysmetria: A positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry. Proceedings of the National Academy of Sciences of the United States of America, 93, 9985-9990. Baddeley, A. (1992). Working memory. Science, 255, 556-559. Barrantes-Vidal, N., Aguilera, M., Campanera, S., Fatjo-Vilas, M., Guitart, M., Miret, S., …Fananas L. (2007). Working memory in siblings of schizophrenia patients. Schizophrenia Research, 95, 70-75. Bell, M. D., Lysaker, P. H., Beam-Goulet, J. L., Milstein, R. M., & Lindenmayer, J. P. (1994). Five-component model of schizophrenia: Assessing the factorial invariance of the positive and negative syndrome scale. Psychiatry Research, 52, 295-303. Berman, K. F., Doran, A. R., Pickar, D., & Weinberger, D. R. (1993). Is the mechanism of prefrontal hypofunction in depression the same as in schizophrenia - regional cerebral blood-flow during cognitive activation. British Journal of Psychiatry, 162, 183-192. Bertollo, D. N., Cowen, M. A., & Levy, A. V. (1996). Hypometabolism in olfactory cortical projection areas of male patients with schizophrenia: An initial positron emission tomography study. Psychiatry Research, 60, 113-116. Buchanan, R. W., Vladar, K., Barta, P. E., & Pearlson, G. D. (1998). Structural evaluation of the prefrontal cortex in schizophrenia. The American Journal of Psychiatry, 155, 1049-1055. Bull, R., & Johnston, R. S. (1997). Children's arithmetical difficulties: Contributions from processing speed, item identification, and short-term memory. Journal of experimental child psychology, 65, 1-24. Callicott, J. H., Egan, M. F., Mattay, V. S., Bertolino, A., Bone, A. D., Verchinksi, B., & Weinberger D.R. (2003). Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. The American Journal of Psychiatry, 160, 709-719. Cameron, A. M., Oram, J., Geffen, G. M., Kavanagh, D. J., McGrath, J. J., & Geffen, L. B. (2002). Working memory correlates of three symptom clusters in schizophrenia. Psychiatry research, 110, 49-61. Carter, C., Robertson, L., Nordahl, T., Chaderjian, M., Kraft, L., & O'Shora-Celaya, L. (1996). Spatial working memory deficits and their relationship to negative symptoms in unmedicated schizophrenia patients. Biological psychiatry, 40, 930-932. Christodoulou, C., DeLuca, J., Ricker, J. H., Madigan, N. K., Bly, B. M., Lange, G., …Ni, A.C. (2001). Functional magnetic resonance imaging of working memory impairment after traumatic brain injury. Journal of Neurology, Neurosurgery, and Psychiatry, 71, 161-168. Cleghorn, J. M., Franco, S., Szechtman, B., Kaplan, R. D., Szechtman, H., Brown, G. M., … Garnett E. S. (1992). Toward a brain map of auditory hallucinations. American Journal of Psychiatry, 149, 1062-1069. Conklin, H. M., Curtis, C. E., Katsanis, J., & Iacono, W. G. (2000). Verbal working memory impairment in schizophrenia patients and their first-degree relatives: Evidence from the digit span task. The American Journal of Psychiatry, 157, 275-277. Corsi, P. M. (1972). Human memory and the medial temporal region of the brain. Dissertation Abstracts International, 34, 891. D’Elia, L. F., Satz, P., Uchiyama, C. L., & White, T. . (1996). Color Trails Test. Professional manual. Odessa, FL: Psychological Assessment Resources. Dreisbach, G., & Haider, H. (2009). How task representations guide attention: Further evidence for the shielding function of task sets. Journal of Experimental Psychology. Learning, Memory, and Cognition, 35, 477-486. Duncan, J., & Owen, A. M. (2000). Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends in Neurosciences, 23, 475-483. Glahn, D. C., Ragland, J. D., Abramoff, A., Barrett, J., Laird, A. R., Bearden, C. E., & Velligan, D. I. (2005). Beyond hypofrontality: A quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia. Human Brain Mapping, 25, 60-69. Gold, J. M., Carpenter, C., Randolph, C., Goldberg, T. E., & Weinberger, D. R. (1997). Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia. Archives of General Psychiatry, 54, 159-165. Goldberg, T., & Gold, J. (2002). Neurocognitive functioning in patients with schizophrenia: An overview. In K. Davis, D. Charney, J. Coyle & C. Nemeroff (Eds.), Neuropsychopharmacology: The fifth generation of progress. (pp. 657-670). Philadelphia, Pa.: Lippincott Williams & Wilkins. Goldberg, T. E., Ragland, J. D., Torrey, E. F., Gold, J. M., Bigelow, L. B., & Weinberger, D. R. (1990). Neuropsychological assessment of monozygotic twins discordant for schizophrenia. Archives of General Psychiatry, 47, 1066-1072. Goldberg, T. E., & Weinberger, D. R. (1995). Thought disorder, working memory and attention: Interrelationships and the effects of neuroleptic medications. International Clinical Psychopharmacology, 10 (Suppl. 3), 99-104. Golden, C. (1978). Stroop Color and Word Test Manual (Vol. Cat. 301SOM. ). Chicago, Ill.: Stoelting Company. Green, M. F., Kern, R. S., Braff, D. L., & Mintz, J. (2000). Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the 'right stuff'? Schizophrenia Bulletin, 26, 119-136. Green, M. F., Marshall, B. D., Jr., Wirshing, W. C., Ames, D., Marder, S. R., McGurk, S., … Mintz J. (1997). Does risperidone improve verbal working memory in treatment-resistant schizophrenia? The American Journal of Psychiatry, 154, 799-804. Harms, M. P., Wang, L., Campanella, C., Aldridge, K., Moffitt, A. J., Kuelper, J., … Csernansky J. G. (2010). Structural abnormalities in gyri of the prefrontal cortex in individuals with schizophrenia and their unaffected siblings. British Journal of Psychiatry, 196, 150-157. Heaton, R. K. (1981). Wisconsin Card Sorting Test manual. Odessa, FL: Psychological Assessment Resources. Hua, M. S., Chang, S. H., & Chen, S. T. (1997). Factor structure and age effects with an aphasia test battery in normal Taiwanese adults. Neuropsychology, 11, 156-162. Hua, M. S., Chang, B. S., Lin, K. N., Yang, J. M., Lu, S. R., & Chen, H. Y. (2005). Wechsler Memory Scale (WMS), Third Edition. Taipei, Taiwan: The Chinese Behavioral Science Corporation. Huguelet, P., Zanello, A., & Nicastro, R. (2000). A study of visual and auditory verbal working memory in schizophrenic patients compared to healthy subjects. European Archives of Psychiatry and Clinical Neuroscience, 250, 79-85. Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276. Kiefer, M., Apel, A., & Weisbrod, M. (2002). Arithmetic fact retrieval and working memory in schizophrenia. Schizophrenia Research, 53, 219-227. Konishi, S., Kawazu, M., Uchida, I., Kikyo, H., Asakura, I., & Miyashita, Y. (1999). Contribution of working memory to transient activation in human inferior prefrontal cortex during performance of the Wisconsin Card Sorting Test. Cerebral Cortex, 9, 745-753. Lancon, C., Auquier, P., Nayt, G., & Reine, G. (2000). Stability of the five-factor structure of the Positive and Negative Syndrome Scale (PANSS). Schizophrenia Research, 42, 231-239. Lavie, N., Hirst, A., de Fockert, J. W., & Viding, E. (2004). Load theory of selective attention and cognitive control. Journal of Experimental Psychology. General, 133, 339-354. Lee, J., & Park, S. (2005). Working memory impairments in schizophrenia: A meta-analysis. Journal of Abnormal Psychology, 114, 599-611. Levin, H. S. (1983). Paced Auditory Serial Addition Task-revised (Unpublished manuscript). University of Texas Medical Branch at Galveston, TX: University of Texas Medical Branch at Galveston, Neurosurgery Division. Liddle, P. F. (1992). Syndromes of schizophrenia on factor analysis. The British Journal of Psychiatry : The Journal of Mental Science, 161, 861. Liddle, P. F., Friston, K. J., Frith, C. D., Hirsch, S. R., Jones, T., & Frackowiak, R. S. (1992). Patterns of cerebral blood flow in schizophrenia. The British Journal of Psychiatry : The Journal of Mental Science, 160, 179-186. Lindenmayer, J. P., Bernstein-Hyman, R., & Grochowski, S. (1994). Five-factor model of schizophrenia. Initial validation. The Journal of Nervous and Mental Disease, 182, 631-638. Liu, C. C., Chen, C. H., Hwu, H. G., Shiu, S. Y., Hua, M. S., Hwang, T. J., … Chen, W. J. (2012). Medium-term course and outcome of schizophrenia depicted by the sixth-month subtype after an acute episode. Journal of the Formosan Medical Association, 111, 265-274. Liu, S. K., Hsieh, M. H., Huang, T. J., Liu, C. M., Liu, C. C., Hua, M. S., … Hwu, H. G. (2006). Patterns and clinical correlates of neuropsychologic deficits in patients with schizophrenia. Journal of the Formosan Medical Association, 105, 978-991. MacDonald, A. W., 3rd, Cohen, J. D., Stenger, V. A., & Carter, C. S. (2000). Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science, 288, 1835-1838. Marder, S. R., Davis, J. M., & Chouinard, G. (1997). The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: Combined results of the North American trials. The Journal of Clinical Psychiatry, 58, 538-546. Mass, R., Schoemig, T., Hitschfeld, K., Wall, E., & Haasen, C. (2000). Psychopathological syndromes of schizophrenia: Evaluation of the dimensional structure of the positive and negative syndrome scale. Schizophrenia Bulletin, 26, 167-177. Menon, V., Anagnoson, R. T., Mathalon, D. H., Glover, G. H., & Pfefferbaum, A. (2001). Functional neuroanatomy of auditory working memory in schizophrenia: Relation to positive and negative symptoms. Neuroimage, 13, 433-446. Miller, G. A. (1960). Plans and the structure of behavior. New York : Holt. Moscovitch, M. (1994). Cognitive resources and the dual-task interference effects at retrieval in normal people: The role of the frontal lobes and medial temporal cortex. Neuropsychology, 8, 524-534. Murphy, B. L., Roth, R. H., & Arnsten, A. F. (1997). Clozapine reverses the spatial working memory deficits induced by FG7142 in monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 16, 433-437. Nelson, H. E. (1976). A modified card sorting test sensitive to frontal lobe defects. Cortex: A Journal Devoted to The Study of The Nervous System and Behavior, 12, 313-324. Nuechterlein, K. H., Green, M. F., Kern, R. S., Baade, L. E., Barch, D. M., Cohen, J. D., … Marder, S. R. (2008). The MATRICS Consensus Cognitive Battery, part 1: Test selection, reliability, and validity. The American Journal of Psychiatry, 165, 203-213. Park, S., & Holzman, P. S. (1992). Schizophrenics show spatial working memory deficits. Archives of General Psychiatry, 49, 975-982. Peralta, V., & Cuesta, M. J. (1994). Psychometric properties of the positive and negative syndrome scale (PANSS) in schizophrenia. Psychiatry Research, 53, 31-40. Perlstein, W. M., Carter, C. S., Noll, D. C., & Cohen, J. D. (2001). Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia. The American Journal of Psychiatry, 158, 1105-1113. Perry, W., Heaton, R. K., Potterat, E., Roebuck, T., Minassian, A., & Braff, D. L. (2001). Working memory in schizophrenia: Transient 'online' storage versus executive functioning. Schizophrenia Bulletin, 27, 157-176. Pukrop, R., Matuschek, E., Ruhrmann, S., Brockhaus-Dumke, A., Tendolkar, I., Bertsch, A., & Klosterkotter, J.. (2003). Dimensions of working memory dysfunction in schizophrenia. Schizophrenia Research, 62, 259-268. Reitan, R. M., & Wolfson, D. (1993). The Halstead-Reitan Neuropsychological Test Battery: Theory and clinical interpretation. Tucson, AZ: Neuropsychological Press. Rosen, V. M., & Engle, R. W. (1997). The role of working memory capacity in retrieval. Journal of Experimental Psychology. General, 126, 211-227. Sanchez-Cubillo, I., Perianez, J. A., Adrover-Roig, D., Rodriguez-Sanchez, J. M., Rios-Lago, M., Tirapu, J., Barcelo, F. (2009). Construct validity of the Trail Making Test: Role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. Journal of the International Neuropsychological Society, 15, 438-450. Schmeichel, B. J. (2007). Attention control, memory updating, and emotion regulation temporarily reduce the capacity for executive control. Journal of Experimental Psychology. General, 136, 241-255. Selemon, L. D., Rajkowska, G., & Goldman-Rakic, P. S. (1995). Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Archives of General Psychiatry, 52, 805-818; discussion 819-820. Silver, H., Feldman, P., Bilker, W., & Gur, R. C. (2003). Working memory deficit as a core neuropsychological dysfunction in schizophrenia. American Journal of Psychiatry, 160, 1809-1816. Soutschek, A., Strobach, T., & Schubert, T. (2013). Working memory demands modulate cognitive control in the Stroop paradigm. Psychological research, 77, 333-347. Tagamets, M. A., & Horwitz, B. (2000). A model of working memory: Bridging the gap between electrophysiology and human brain imaging. Neural Networks : the Official Journal of the International Neural Network Society, 13, 941-952. Troyer, A. K., Moscovitch, M., & Winocur, G. (1997). Clustering and switching as two components of verbal fluency: Evidence from younger and older healthy adults. Neuropsychology, 11, 138-146. Twamley, E. W., Palmer, B. W., Jeste, D. V., Taylor, M. J., & Heaton, R. K. (2006). Transient and executive function working memory in schizophrenia. Schizophrenia Research, 87, 185-190. Ward, A., & Mann, T. (2000). Don't mind if I do: Disinhibited eating under cognitive load. Journal of Personality and Social Psychology, 78, 753-763. Wood, S. J., Pantelis, C., Proffitt, T., Phillips, L. J., Stuart, G. W., Buchanan, J. A., … McGorry P. D. (2003). Spatial working memory ability is a marker of risk-for-psychosis. Psychological Medicine, 33, 1239-1247. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/62280 | - |
| dc.description.abstract | 研究背景：工作記憶缺損是各類腦部疾患病人常見的功能障礙之一，近年來，工作記憶的概念愈來愈受到重視。過去研究中用來評估工作記憶的工具相當多樣，其中在國外的研究中發現魏氏成人智力測驗中的「數—字序列分測驗」具有良好的信效度與臨床實用價值。然而，國人，尤其是老年人口，對英語字母有欠熟悉，大大降低了該分測驗在台灣的實用性。雖然彭鍾伃和花茂棽在2009年發展出『台大數字奇偶序列測驗』來取代數-字序列分測驗。但由於缺乏臨床病人的研究資料佐證，此測驗在臨床實務上的應用性仍未確知。因此，本研究目的主要為：一、收集分析臨床精神分裂症病人資料，重新檢驗台大數字奇偶序列測驗的心理計量特性；二、進一步探討奇偶測驗在當前和未來實務工作方面的實用性；三、探討工作記憶與臨床症狀之相關性。實驗設計：病例對照研究法。研究場所：台大醫院精神部門診。參與者：32位精神分裂症患者及32位年齡和性別相配之健康受試者。主要結果變項：運用國內常用的工作記憶測驗了解精神分裂症患者的工作記憶缺損，並比較患者在各個測驗的表現。並以智力和其他神經心理測驗評估患者的神經認知功能。結果：患者在各種工作記憶測驗表現皆較正常對照組低，同時在奇偶測驗表現有缺損的患者，在其他工作記憶測驗上也表現出類似的缺損，但患者在中文版數—字序列分測驗之表現與其他工作記憶測驗較不一致。進一步分析比較不能完成中文版數—字序列分測驗的患者和能夠完成的患者，發現不能完成的患者在其他神經心理功能（如：記憶力、執行功能）有較多的功能缺損。工作記憶與臨床症狀無顯著相關。結論：在排除人口學因素的影響之後，精神分裂症患者確實有工作記憶功能的損傷。台大奇偶測驗擁有良好的效度亦能廣泛的運用在臨床實務上。中文版數—字序列分測驗在實務的使用上確有其限制，奇偶測驗能排除語言的影響，其後續發展與推廣確有其必要性。 | zh_TW |
| dc.description.abstract | Importance: To investigate brain function of patients with brain diseases, an efficient tool to assessing working memory (WM) function is needed. The National Taiwan University Odd-Even Number Sequencing Test (TOENS) had developed to minimize culture and linguistic bias, and the present study was thus to explore the construct validity and the practical utility of this test assessing the WM function in patients with schizophrenia. Objective: (1) Re-examining the validity of the TOENS measuring WM in patients with schizophrenia. (2) To Investigate the clinical application of the TOENS and examine the possibility of replacing the Letter-Number-Sequencing (LNS) subtest in the WAIS-IV Taiwan version. (3) Investigating the relationship between clinical symptoms and WM function. Design: Case-control study. Setting: Outpatient clinic of the Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan. Participants: Thirty-two patients with schizophrenia and demographically matched controls. Main Outcome Measures: Patients’ WM function and neurocognitive function (including general IQ, executive function, and memory function) were assessed and compare by neuropsychological tests. Results: Patients performed worse on all WM tests. Patients’ performance on LNS of the WAIS-III-Taiwan version was less consistent with the other WM tests. There were significant correlations between the TOENS and other neuropsychological tests involved frontal function. There was no significant correlation between demographic data, illness duration, clinical symptoms and the TOENS performance. Conclusions: Based on the present results, our patients generally have working memory deficits. This study confirmed that the TOENS has a good validity and indicated the TOENS can be a candidate to replace the LNS subtest of the WAIS-III Taiwan version. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-16T13:38:22Z (GMT). No. of bitstreams: 1 ntu-102-R99227205-1.pdf: 1405662 bytes, checksum: c7f0c2e6da77479e30520c3d994939e7 (MD5) Previous issue date: 2013 | en |
| dc.description.tableofcontents | INTRODUCTION 1
METHODS 7 Participants 7 Measurements 7 Procedure 10 Statistical Analyses 10 RESULTS 12 CONCLUSION 14 ACKNOWLEDGMENT 20 REFERENCES 21 Chinese References 21 English References 21 APPENDIX 29 Informed Consent Form 29 TABLES 36 | |
| dc.language.iso | en | |
| dc.subject | 神經認知 | zh_TW |
| dc.subject | 精神分裂症 | zh_TW |
| dc.subject | 工作記憶 | zh_TW |
| dc.subject | 奇偶測驗 | zh_TW |
| dc.subject | schizophrenia | en |
| dc.subject | neurocognition | en |
| dc.subject | the TOENS | en |
| dc.subject | working memory | en |
| dc.title | 台大奇偶序列測驗:評量精神分裂症患者工作記憶功能的適用性研究 | zh_TW |
| dc.title | The National Taiwan University Odd-Even Number Sequencing Test: An Alternative Measuring Working Memory in Patients with Schizophrenia | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 101-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳心怡(Chen, Hsin-Yi),劉震鐘(Chen-Chung Liu) | |
| dc.subject.keyword | 精神分裂症,工作記憶,奇偶測驗,神經認知, | zh_TW |
| dc.subject.keyword | schizophrenia,working memory,the TOENS,neurocognition, | en |
| dc.relation.page | 41 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2013-07-16 | |
| dc.contributor.author-college | 理學院 | zh_TW |
| dc.contributor.author-dept | 心理學研究所 | zh_TW |
| 顯示於系所單位： | 心理學系 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-102-1.pdf 未授權公開取用 | 1.37 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。