請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/60646
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 李永凌(Yungling Leo Lee) | |
dc.contributor.author | Ming-Hung Lin | en |
dc.contributor.author | 林明弘 | zh_TW |
dc.date.accessioned | 2021-06-16T10:24:35Z | - |
dc.date.available | 2018-09-24 | |
dc.date.copyright | 2013-09-24 | |
dc.date.issued | 2013 | |
dc.date.submitted | 2013-08-16 | |
dc.identifier.citation | Benowitz NL (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiologic Reviews 18(2): 188-204.
Benowitz NL, Kuyt F and Jacob P, 3rd (1982). Circadian blood nicotine concentrations during cigarette smoking. Clinical Pharmacology and Therapeutics 32(6): 758-764. Biagini JM, LeMasters GK, Ryan PH, Levin L, Reponen T, Bernstein DI, Villareal M, Khurana Hershey GK, Burkle J and Lockey J (2006). Environmental risk factors of rhinitis in early infancy. Pediatric Allergy and Immunology 17(4): 278-284. Bliwise DL, Nekich JC and Dement WC (1991). Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population. Chest 99(3): 600-608. Bloom JW, Kaltenborn WT and Quan SF (1988). Risk factors in a general population for snoring. Importance of cigarette smoking and obesity. Chest 93(4): 678-683. Bureau of Health Promotion DoH, Taiwan. (2008). 民國97年成人吸菸行為調查. Retrieved Jan 16, 2011, from http://olap.bhp.doh.gov.tw/search/ListHealth1.aspx?menu=1&mode=12&year=97&sel=0. Bureau of Health Promotion DoH, Taiwan. (2013). Global Youth Tobacco Survey 2012. Retrieved June 21, 2013, from http://www.bhp.doh.gov.tw/bhpnet/Web/Column/ColumnContent.aspx?id=201304290001&email=cecillia1226%40bali.doh.gov.tw. Burr ML, Anderson HR, Austin JB, Harkins LS, Kaur B, Strachan DP and Warner JO (1999). Respiratory symptoms and home environment in children: a national survey. Thorax 54(1): 27-32. Buysse DJ, Reynolds CF, 3rd, Monk TH, Berman SR and Kupfer DJ (1989). The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Research 28(2): 193-213. Centers for Disease Control and Prevention US (2010a). Vital signs: current cigarette smoking among adults aged >or=18 years --- United States, 2009. MMWR. Morbidity and Mortality Weekly Report 59(35): 1135-1140. Centers for Disease Control and Prevention US (2010b). Vital signs: nonsmokers' exposure to secondhand smoke --- United States, 1999-2008. MMWR. Morbidity and Mortality Weekly Report 59(35): 1141-1146. Chan CC, Chen SC and Wang JD (1995). Relationship between indoor nicotine concentrations, time-activity data, and urine cotinine-creatinine ratios in evaluating children's exposure to environmental tobacco smoke. Archives of Environmental Health 50(3): 230-234. Chugh IM, Khanna P and Shah A (2006). Nocturnal symptoms and sleep disturbances in clinically stable asthmatic children. Asian Pacific Journal of Allergy and Immunology 24(2-3): 135-142. Corbo GM, Fuciarelli F, Foresi A and De Benedetto F (1989). Snoring in children: association with respiratory symptoms and passive smoking. British Medical Journal (Clinical Research Ed.) 299(6714): 1491-1494. Davila EP, Lee DJ, Fleming LE, LeBlanc WG, Arheart K, Dietz N, Lewis JE, McCollister K, Caban-Martinez A and Bandiera F (2010). Sleep disorders and secondhand smoke exposure in the U.S. population. Nicotine & Tobacco Research 12(3): 294-299. Davis RA, Stiles MF, deBethizy JD and Reynolds JH (1991). Dietary nicotine: a source of urinary cotinine. Food and Chemical Toxicology 29(12): 821-827. De S, Leong SC, Fenton JE, Carter SD, Clarke RW and Jones AS (2011). The effect of passive smoking on the levels of matrix metalloproteinase 9 in nasal secretions of children. American Journal of Rhinology and Allergy 25(4): 226-230. Diette GB, Markson L, Skinner EA, Nguyen TT, Algatt-Bergstrom P and Wu AW (2000). Nocturnal asthma in children affects school attendance, school performance, and parents' work attendance. Archives of Pediatrics and Adolescent Medicine 154(9): 923-928. Franklin KA, Gislason T, Omenaas E, Jogi R, Jensen EJ, Lindberg E, Gunnbjornsdottir M, Nystrom L, Laerum BN, Bjornsson E, Toren K and Janson C (2004). The influence of active and passive smoking on habitual snoring. American Journal of Respiratory and Critical Care Medicine 170(7): 799-803. Gau SF and Soong WT (1995). Sleep problems of junior high school students in Taipei. Sleep 18(8): 667-673. Gregory AM, Van der Ende J, Willis TA and Verhulst FC (2008). Parent-reported sleep problems during development and self-reported anxiety/depression, attention problems, and aggressive behavior later in life. Archives of Pediatrics and Adolescent Medicine 162(4): 330-335. Guzman-Marin R, Alam MN, Mihailescu S, Szymusiak R, McGinty D and Drucker-Colin R (2001). Subcutaneous administration of nicotine changes dorsal raphe serotonergic neurons discharge rate during REM sleep. Brain Research 888(2): 321-325. Hart CN and Jelalian E (2008). Shortened sleep duration is associated with pediatric overweight. Behavioral Sleep Medicine 6(4): 251-267. Haufroid V and Lison D (1998). Urinary cotinine as a tobacco-smoke exposure index: a minireview. International Archives of Occupational and Environmental Health 71(3): 162-168. Holmen TL, Barrett-Connor E, Holmen J and Bjermer L (2000). Health problems in teenage daily smokers versus nonsmokers, Norway, 1995-1997: the Nord-Trondelag Health Study. American Journal of Epidemiology 151(2): 148-155. Huang YS, Wang CH and Guilleminault C (2010). An epidemiologic study of sleep problems among adolescents in North Taiwan. Sleep Medicine 11(10): 1035-1042. Hughes JR, Gust SW, Skoog K, Keenan RM and Fenwick JW (1991). Symptoms of tobacco withdrawal. A replication and extension. Archives of General Psychiatry 48(1): 52-59. Hughes JR and Hatsukami D (1986). Signs and symptoms of tobacco withdrawal. Archives of General Psychiatry 43(3): 289-294. Jaehne A, Loessl B, Barkai Z, Riemann D and Hornyak M (2009). Effects of nicotine on sleep during consumption, withdrawal and replacement therapy. Sleep Medicine Reviews 13(5): 363-377. Johansson A, Ludvigsson J and Hermansson G (2008). Adverse health effects related to tobacco smoke exposure in a cohort of three-year olds. Acta Paediatrica 97(3): 354-357. Juniper EF and Guyatt GH (1991). Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clinical and Experimental Allergy 21(1): 77-83. Juniper EF, Thompson AK, Ferrie PJ and Roberts JN (1999). Validation of the standardized version of the Rhinoconjunctivitis Quality of Life Questionnaire. The Journal of allergy and clinical immunology 104(2 Pt 1): 364-369. Kurosaka F, Nakatani Y, Terada T, Tanaka A, Ikeuchi H, Hayakawa A, Konohana A, Oota K and Nishio H (2006). Current cat ownership may be associated with the lower prevalence of atopic dermatitis, allergic rhinitis, and Japanese cedar pollinosis in schoolchildren in Himeji, Japan. Pediatric Allergy and Immunology 17(1): 22-28. Lewis DA (2001). Sleep in patients with asthma and chronic obstructive pulmonary disease. Current Opinion in Pulmonary Medicine 7(2): 105-112. Leynaert B, Bousquet J, Henry C, Liard R and Neukirch F (1997). Is bronchial hyperresponsiveness more frequent in women than in men? A population-based study. American Journal of Respiratory and Critical Care Medicine 156(5): 1413-1420. Marshall NS, Almqvist C, Grunstein RR and Marks GB (2007). Predictors for snoring in children with rhinitis at Age 5. Pediatric Pulmonology 42(7): 584-591. Mitchell EA and Stewart AW (2001). The ecological relationship of tobacco smoking to the prevalence of symptoms of asthma and other atopic diseases in children: the International Study of Asthma and Allergies in Childhood (ISAAC). European Journal of Epidemiology 17(7): 667-673. Montaño-Velázquez BB, Navarrete RC, Mogica Martinez MD, Becerril-Ángeles M and Jáuregui-Renaud K (2011). Rhinomanometry in young patients with perennial allergic rhinitis with/without recent exposure to tobacco smoke. Clinical Otolaryngology 36(4): 320-324. Montgomery-Downs HE and Gozal D (2006). Snore-associated sleep fragmentation in infancy: mental development effects and contribution of secondhand cigarette smoke exposure. Pediatrics 117(3): e496-502. Morkjaroenpong V, Rand CS, Butz AM, Huss K, Eggleston P, Malveaux FJ and Bartlett SJ (2002). Environmental tobacco smoke exposure and nocturnal symptoms among inner-city children with asthma. The Journal of allergy and clinical immunology 110(1): 147-153. Moyer TP, Charlson JR, Enger RJ, Dale LC, Ebbert JO, Schroeder DR and Hurt RD (2002). Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles. Clinical Chemistry 48(9): 1460-1471. Nakata A, Takahashi M, Haratani T, Ikeda T, Hojou M, Fujioka Y and Araki S (2008). Association of active and passive smoking with sleep disturbances and short sleep duration among japanese working population. International Journal of Behavioral Medicine 15(2): 81-91. Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ and Pendergraft TB (2004). Development of the asthma control test: A survey for assessing asthma control. The Journal of allergy and clinical immunology 113(1): 59-65. Ohida T, Kaneita Y, Osaki Y, Harano S, Tanihata T, Takemura S, Wada K, Kanda H, Hayashi K and Uchiyama M (2007). Is passive smoking associated with sleep disturbance among pregnant women? Sleep 30(9): 1155-1161. Okoli CTC, Kelly T and Hahn EJ (2007). Secondhand smoke and nicotine exposure: A brief review. Addictive Behaviors 32(10): 1977-1988. Owens J (2008). Classification and epidemiology of childhood sleep disorders. Primary Care; Clinics in Office Practice 35(3): 533-546, vii. Owens JA, Maxim R, Nobile C, McGuinn M and Msall M (2000). Parental and self-report of sleep in children with attention-deficit/hyperactivity disorder. Archives of Pediatrics and Adolescent Medicine 154(6): 549-555. Paavonen EJ, Aronen ET, Moilanen I, Piha J, Rasanen E, Tamminen T and Almqvist F (2000). Sleep problems of school-aged children: a complementary view. Acta Paediatrica 89(2): 223-228. Phillips BA and Danner FJ (1995). Cigarette smoking and sleep disturbance. Archives of Internal Medicine 155(7): 734-737. Raherison C, Penard-Morand C, Moreau D, Caillaud D, Charpin D, Kopfersmitt C, Lavaud F, Taytard A and Annesi-maesano I (2007). In utero and childhood exposure to parental tobacco smoke, and allergies in schoolchildren. Respiratory Medicine 101(1): 107-117. Sabanayagam C and Shankar A (2011). The association between active smoking, smokeless tobacco, second-hand smoke exposure and insufficient sleep. Sleep Medicine 12(1): 7-11. Schatz M, Sorkness CA, Li JT, Marcus P, Murray JJ, Nathan RA, Kosinski M, Pendergraft TB and Jhingran P (2006). Asthma Control Test: Reliability, validity, and responsiveness in patients not previously followed by asthma specialists. The Journal of allergy and clinical immunology 117(3): 549-556. Singh GK and Kenney MK (2013). Rising prevalence and neighborhood, social, and behavioral determinants of sleep problems in US children and adolescents, 2003-2012. Sleep Disorders 2013: 394320. Soldatos CR, Kales JD, Scharf MB, Bixler EO and Kales A (1980). Cigarette smoking associated with sleep difficulty. Science 207(4430): 551-553. Stazi MA, Sampogna F, Montagano G, Grandolfo ME, Couilliot MF and Annesi-Maesano I (2002). Early life factors related to clinical manifestations of atopic disease but not to skin-prick test positivity in young children. Pediatric Allergy and Immunology 13(2): 105-112. Strachan DP and Cook DG (1998). Health effects of passive smoking. 5. Parental smoking and allergic sensitisation in children. Thorax 53(2): 117-123. Tsai CH, Huang JH, Hwang BF and Lee YL (2010). Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan. Respiratory Research 11: 11. Tsai PS, Wang SY, Wang MY, Su CT, Yang TT, Huang CJ and Fang SC (2005). Psychometric evaluation of the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI) in primary insomnia and control subjects. Quality of Life Research 14(8): 1943-1952. Tu X, Cai H, Gao YT, Wu X, Ji BT, Yang G, Li H, Zheng W and Shu XO (2012). Sleep duration and its correlates in middle-aged and elderly Chinese women: The Shanghai Women's Health Study. Sleep Medicine 13(9): 1138-1145. Tung KY, Wu KY, Tsai CH, Su MW, Chen CH, Lin MH, Chen YC, Wu WC and Lee YL (2013). Association of time–location patterns with urinary cotinine among asthmatic children under household environmental tobacco smoke exposure. Environmental Research 124: 7-12. Tuomi T, Johnsson T and Reijula K (1999). Analysis of nicotine, 3-hydroxycotinine, cotinine, and caffeine in urine of passive smokers by HPLC-tandem mass spectrometry. Clinical Chemistry 45(12): 2164-2172. Virkkula P, Liukkonen K, Suomalainen AK, Aronen ET, Kirjavainen T and Pitkaranta A (2011). Parental smoking, nasal resistance and rhinitis in children. Acta Paediatrica 100(9): 1234-1238. Wetter DW and Young TB (1994). The relation between cigarette smoking and sleep disturbance. Preventive Medicine 23(3): 328-334. Wetter DW, Young TB, Bidwell TR, Badr MS and Palta M (1994). Smoking as a risk factor for sleep-disordered breathing. Archives of Internal Medicine 154(19): 2219-2224. Willers S, Axmon A, Feyerabend C, Nielsen J, Skarping G and Skerfving S (2000). Assessment of environmental tobacco smoke exposure in children with asthmatic symptoms by questionnaire and cotinine concentrations in plasma, saliva, and urine. Journal of Clinical Epidemiology 53(7): 715-721. Willes SR, Fitzgerald TK, Proud D, Haley NJ and Bascom R (1998). Acute respiratory response to prolonged, moderate levels of sidestream tobacco smoke. Journal of Toxicology & Environmental Health: Part A 53(3): 193-209. Yolton K, Xu Y, Khoury J, Succop P, Lanphear B, Beebe DW and Owens J (2010). Associations between secondhand smoke exposure and sleep patterns in children. Pediatrics 125(2): e261-268. Zhang L, Samet J, Caffo B and Punjabi NM (2006). Cigarette smoking and nocturnal sleep architecture. American Journal of Epidemiology 164(6): 529-537. Zuraimi MS, Tham KW, Chew FT, Ooi PL and David K (2008). Home exposures to environmental tobacco smoke and allergic symptoms among young children in Singapore. International Archives of Allergy and Immunology 146(1): 57-65. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/60646 | - |
dc.description.abstract | 背景:台灣學童與青少年睡眠問題的盛行率約10~35%。青少年的睡眠問題已知會造成其學校表現、身心健康及行為等方面的不良影響。而二手菸暴露對於青少年睡眠品質及鼻眼過敏症狀的影響仍未有定論。
研究目的:利用結構性問卷及生物檢體的量測,探討二手菸暴露對於青少年睡眠品質及鼻眼過敏症狀的影響。 研究方法:本研究於2009年7月至2010年8月間,於北台灣七所國中及兩家醫院招募451位四至九年級之學童自願者,接受一對一面談,自填結構式問卷並留取尿液檢體。問卷中以中文版匹茲堡睡眠品質量表(PSQI)評估其睡眠狀況,以中文版鼻結膜炎生活品質問卷(RQLQ)評估其鼻眼過敏症狀,且於問卷中詳細詢問二手菸暴露情形,並測量其尿液中cotinine濃度與肌酸酐之比值(CCR)作為二手菸暴露程度的生物指標。最後利用邏輯斯迴歸及複線性迴歸模式作資料分析。 研究結果:在這451位青少年中,有氣喘病史者較無氣喘者有較高之睡眠問題盛行率(20.2% vs. 11%, P = 0.008)。在調整年齡、性別、身體質量指數、異位性皮膚炎、過敏性鼻炎、戶外運動時間、重要環境因子及青春期等可能之干擾因素後,有氣喘的青少年若尿液中CCR越高,睡眠品質不佳的危險性越大(aOR = 3.46, 95%CI = 1.20~10.0, P for trend = 0.01);目前家中有二手菸暴露者,睡眠品質不佳的危險性是家中沒有二手菸暴露者的2.69倍(95%CI 1.21~6.00);若家中有兩人以上吸菸,則睡眠品質不佳的危險性是家中無人吸菸者的4.66倍(95%CI 1.47~14.7)。在沒有氣喘的青少年中也有類似傾向,但未達統計顯著。若以性別做分層,則發現女孩氣喘者睡眠品質受二手菸暴露的影響比男孩氣喘者更大。在PSQI七個面向中,以「睡眠潛伏期」、「睡眠效率」及「日間功能障礙」受二手菸暴露的影響較大。另外,有氣喘的青少年相較於無氣喘者,前者鼻眼過敏症狀較嚴重,而二手菸暴露也會稍加重有氣喘者的鼻眼症狀(β = 0.24, 95%CI = -0.07~0.55, P for trend = 0.07),其中以「日常活動」及「眼部症狀」受二手菸暴露的影響較大。而在無氣喘的青少年中,自陳有二手菸暴露者會有較嚴重的鼻眼症狀,但其尿液CCR量測則未能呈現相同的關係。 結論:本研究發現,青少年受二手菸暴露程度越高,有睡眠問題的危險性越大,尤其是有氣喘病史者及女性。二手菸暴露對青少年之鼻眼過敏症狀亦有不良的影響。這些發現為二手菸防治提供了重要的理由。 | zh_TW |
dc.description.abstract | Background: Sleep problems during childhood and adolescence have been linked with poor school performance, somatic complaints, behavioral problems, and mental health problems. The prevalence of sleep disorders is around 10 ~ 35 % among school-aged children and adolescents in Taiwan. The association between secondhand smoke (SHS) exposure, sleep problems and rhinoconjunctivitis symptoms among adolescents is still inconsistent.
Objective: The aim of this study was to explore the impact of SHS exposure on adolescent sleep quality and rhinoconjunctivitis symptoms, based on biological specimen for exposure measurement and validated questionnaire for outcome assessment. We hypothesized that adolescents undergoing more SHS exposure would have poorer sleep quality and more severe rhinoconjunctivitis symptoms. Methods: Adolescents (n=451) aged 10~16 years were enrolled from the Genetic and Biomarkers Study for Childhood Asthma, which recruited 4-9th grade schoolchildren from 7 junior high schools and 2 hospitals in northern Taiwan from July 2009 to August 2010. All participants received face-to-face interview and completed a comprehensive questionnaire including information on demographic features, environmental factors, Chinese version of the Pittsburg Sleep Quality Index (PSQI) and Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Spot urine of each participant was collected to measure the urinary cotinine/creatinine ratio (CCR). Multiple logistic regression and multiple linear regression models were conducted for analysis. Results: Participants with asthma had higher proportion of poor sleep than those without asthma (20.2% vs. 11.0%, P=0.008). After adjustment for the potential confounders including age, sex, body mass index, atopic diseases, outdoor exercise, pubertal status, and environmental factors such as carpet use, cockroach and mold presence at home, the asthmatic children with increased urinary CCR level had higher risk of poor sleep (aOR = 3.46, 95%CI = 1.20~10.0, P for trend = 0.01). The asthmatic children with current household SHS exposure (aOR = 2.69, 95%CI = 1.21~6.00) or living with two or more smokers at home (aOR = 4.66, 95%CI = 1.47~14.7) also had poorer sleep quality. There were similar findings among non-asthmatic children despite not statistically significant. The adverse effects of SHS exposure on sleep quality were more prominent in asthmatic girls when stratified by gender. Among the 7 components of PSQI, “sleep latency”, “habitual sleep efficiency” and “daytime dysfunction” were most bothered by SHS exposure among asthmatic children. As for the rhinoconjunctivitis symptoms, participants with asthma had significantly higher scores of RQLQ than those without asthma. The asthmatic children with increased urinary CCR level seemed to have higher RQLQ overall scores than those with lowest CCR level (β = 0.24, 95%CI = -0.07~0.55, P for trend = 0.07), that implied worse rhinoconjunctivitis symptoms among asthmatic children exposed to more SHS. “Activity” and “eye symptoms” were the two domains most affected by the SHS exposure. Among the non-asthmatic children, those reported to have SHS exposure were found to have higher RQLQ overall score and the domain scores on “activity”, “sleep”, “non-hayfever symptoms” and “emotional”, even though no positive correlation between urinary CCR level and RQLQ scores. Conclusions: This study demonstrated that adolescents with more SHS exposure had higher risk to suffer from sleep problems, particularly among asthmatic children and girls. SHS exposure also showed adverse impact on the rhinoconjunctivitis symptoms in adolescents. These findings provided important clinical implication for prevention program against secondhand smoke exposure. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T10:24:35Z (GMT). No. of bitstreams: 1 ntu-102-R98846007-1.pdf: 3073320 bytes, checksum: 900149b8ae52b3b1da9e373182a3ea64 (MD5) Previous issue date: 2013 | en |
dc.description.tableofcontents | 誌謝 I
中文摘要 II ABSTRACT IV CONTENTS VII LIST OF FIGURES X LIST OF TABLES XI ABBREVIATIONS XIV CHAPTER 1. INTRODUCTION 1 CHAPTER 2. METHODS 20 2.1 PARTICIPANTS 20 2.2 PHYSICAL MEASUREMENTS 21 2.3 QUESTIONNAIRE 22 2.4 MEASUREMENT OF SECONDHAND SMOKE EXPOSURE 23 2.5 MEASUREMENT OF SLEEP QUALITY 24 2.6 MEASUREMENT OF RHINOCONJUNCTIVITIS SYMPTOMS 27 2.7 DEFINITION OF VARIABLES 30 2.8 STATISTICAL ANALYSES 31 CHAPTER 3. RESULTS 35 3.1 CHARACTERISTICS OF THE STUDY POPULATION 35 3.2 URINARY CCR LEVEL VS. SELF-REPORTED SHS EXPOSURE 36 3.3 SLEEP QUALITY MEASUREMENTS 37 3.4 SECONDHAND SMOKE EXPOSURE AND SLEEP QUALITY 37 3.5 RHINOCONJUNCTIVITIS SYMPTOMS MEASUREMENTS 41 3.6 SECONDHAND SMOKE EXPOSURE AND RHINOCONJUNCTIVITIS SYMPTOMS 42 CHAPTER 4. DISCUSSION 78 4.1 MAIN FINDINGS AND COMPARISONS WITH PREVIOUS STUDIES 78 4.1.1 Clinical characteristics of study population 79 4.1.2 Sleep problems 80 4.1.3 Secondhand smoke exposure and sleep quality 81 4.1.4 Secondhand smoke exposure and rhinoconjunctivitis symptoms 85 4.2 POSTULATED MECHANISMS 88 4.3 STUDY STRENGTHS AND LIMITATIONS 92 CHAPTER 5. CONCLUSION 99 REFERENCES 100 APPENDIX 109 APPENDIX I. THE CHINESE VERSION OF PITTSBURG SLEEP QUALITY INDEX 109 APPENDIX II. CHINESE VERSION OF THE STANDARDIZED VERSION OF THE RHINOCONJUNCTIVITIS QUALITY OF LIFE QUESTIONNAIRE 111 APPENDIX III. ASTHMA CONTROL TEST 113 | |
dc.language.iso | en | |
dc.title | 二手菸暴露對青少年睡眠品質與鼻眼過敏症狀之影響 | zh_TW |
dc.title | The Impact of Secondhand Smoke Exposure on Sleep Quality and Rhinoconjunctivitis Symptoms in Adolescents | en |
dc.type | Thesis | |
dc.date.schoolyear | 101-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 謝武勳,陳保中,高淑芬 | |
dc.subject.keyword | 二手菸,睡眠品質,鼻眼過敏,青少年,氣喘, | zh_TW |
dc.subject.keyword | secondhand smoke,sleep quality,rhinoconjunctivitis,adolescent,asthma, | en |
dc.relation.page | 113 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2013-08-16 | |
dc.contributor.author-college | 公共衛生學院 | zh_TW |
dc.contributor.author-dept | 流行病學與預防醫學研究所 | zh_TW |
顯示於系所單位: | 流行病學與預防醫學研究所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-102-1.pdf 目前未授權公開取用 | 3 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。