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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 施文彬 | |
dc.contributor.author | Yen-Ting Chen | en |
dc.contributor.author | 陳彥廷 | zh_TW |
dc.date.accessioned | 2021-06-16T09:21:26Z | - |
dc.date.issued | 2017 | |
dc.date.submitted | 2017-06-28 | |
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[2] Lindsay R.G., Bruce A.S., and Gutteridge I.F., “Keratoconus associated with continual eye rubbing due to punctal agenesis.” Cornea. 19(4), 567-569 (2000). [3] McMonnies C.W. “Mechanisms of rubbing-related corneal trauma in keratoconus.”Cornea. 28(6), 607-615 (2009). [4] Balasubramanian S.A., Pye D.C., and Willcox M.D., “Effects of eye rubbing on the levels of protease, protease activity and cytokines in tears: relevance in keratoconus” Clin Exp Optom. 16, 54–59 (2002). [5] McMonnies C.W., “Abnormal rubbing and keratectasia.” Eye Contact Lens 33(6 Pt 1), 265-271 (2007). [6] Sugar J., Macsai M.S., “What causes keratoconus?” Cornea. 31(6), 716-719 (2012). [7] Kurita Y., Kempf R., Iida Y., Okude J., Kaneko M., Mishima HK., Tsukamoto H., Sugimoto E., Katakura S., Kobayashi K., and Kiuchi Y.,” Contact-based stiffness sensing of human eye.” IEEE Trans Biomed Eng. 55(2 Pt 1), 739-745 (2008). [8] Bryant M.R., and McDonnell P.J.,” Constitutive laws for biomechanical modeling of refractive surgery.” J Biomech Eng. 118(4), 473-481 (1996). [9] Barros R.C., Van Kooten T.G., and Veeregowda D.H., “Investigation of Friction-induced Damage to the pig cornea.” Ocul Surf. 13(4), 315-320 (2015). [10] Lam A.K., Hon Y., Leung L.K., and Lam D.C., “Repeatability of a novel corneal indentation device for corneal biomechanical measurement.” Ophthalmic Physiol 35(4), 455-461 (2015). [11] Shaw A.J., Collins M.J., Davis B.A., and Carney L.G., “Eyelid pressure and contact with the ocular surface.” Invest Ophthalmol Vis Sci. 51(4), 1911-1917 (2010). [12] Johnson C.S., Mian S.I., Moroi S., Epstein D., Izatt J., and Afshari N.A., “Role of corneal elasticity in damping of intraocular pressure.” Invest Ophthalmol Vis Sci. 48(6), 2540-2544 (2007). [13] Johnson K. L., “Contact mechanics”, (1985). [14] Greenwood J. A., and Tabor D., “The Friction of Hard Sliders on Lubricated” Proc. Phys. Soc. 71, 989 (1958). [15] Dintwa E., Tijskens E., and Ramon H., “On the accuracy of the Hertz model to describe the normal contact of soft elastic spheres” Granular Matter 10(3), 209-221 (2008). [16] Brizmer V., Kligerman Y., and Etsion I., “The effect of contact conditions and material properties on the elasticity terminus of a spherical contact” International Journal of Solids and Structures 43(18–19), 5736–5749 (2006). [17] Adams M. J., Briscoe B. J., and Johnson S. A., “Friction and lubrication of human skin” Tribology Letters 26(3), pp. 239–253 (2007). [18] Barros R.C., Van Kooten T.G., and Veeregowda D.H., ”Investigation of Friction-induced Damage to the Pig Cornea.” Ocul Surf. 13(4), 315-320 (2015). [19] Kennedy E., and Duma S., “The effects of the extraocular muscles on eye impact force-deflection and globe rupture response.” J Biomech. 41(16), 3297-3302 (2008). [20] Kennedy E. et al., “The Effects of the Extraocular Muscles on Eye Impact Force-Deflection and Globe Rupture Response” J Biomech 41 (16), 3297-3302 (2008). [21] James F. D., and James W. P., “Society for Experimental Mechanics “, 6-1-6-62 (1989). [22] Rachel A. T.; and Zeike A. T., “Photoelastic materials and methods for tissue biomechanics applications.” Opt. Eng. 54(8), 081208 (2015). [23] James F. D., and James W. P., “Manual on experimental stress analysis” (1989). [24] Robert C. S., “A stress-optic law for photoelastic analysis of orthotropic composites.”Experimental Mechanics 10, 210-215 (1970). [25] Zandman F., “Photoelastic effect of the living eye.” Experimental Mechanics 6(5), 19A-22A (1966). [26] Buzard K., “Photoelasticity of the human cornea” [27] Elsheikh A., Alhasso D., and Rama P. “Biomechanical properties of human and porcine corneas.” Exp Eye Res. 86(5), 783-790, (2008). [28] Mills E.W., Smith S.H., Forrest J.C., Aberle E.D., and Judge M.D. “Effects of early post-mortem ageing on intramuscular collagen stability, yield and composition.” Meat Sci. 25(2), 133-141, (1989). | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/59359 | - |
dc.description.abstract | 眼角膜在生活當中所承受的外力有眨眼睛、揉眼睛以及突然的外力衝擊,而揉眼睛是一種很常見的行為,且對於眼睛有相當大的傷害。長期揉眼睛之下可能會造成結膜炎,更嚴重可能會造成角膜組織病變造成圓錐角膜,而導致視力受損更甚亦有可能造成失明。所以,為了更明確的量化揉眼睛對於眼球的傷害,本論文以豬眼睛模擬人眼,探討揉眼睛深度對於眼睛受力的大小和眼睛的變形及所對應的眼壓值進行進一步的探討。所設計的儀器可同時得到靜態揉眼睛的外力、眼壓、接觸面積以及體積變化的資訊。並以數學模型以及有限元素模擬軟體來輔佐證明實驗的可信度。數學模型以小變形模型Hertz contact 為基礎,並且加入眼皮及淚膜對於應力以及壓力分布的影響。此外,本論文中參考真人揉眼睛設計了動態揉眼睛的實驗設備模擬真實揉眼睛的情況,並利用假手指模型進行實驗並探討揉眼睛速度在不同揉眼睛深度之下對於眼角膜的眼睛受力大小和眼內壓值的改變。最後再利用光彈法分析眼角膜上在靜態及動態揉眼之下的應力分布情況,並試著找出最大的應力及所在位置。 | zh_TW |
dc.description.abstract | Cornea always endures the external forces by blinking eyes, rubbing eyes and external strike in ordinary life. If rubbing eyes is a habitual behavior, it will cause the huge damage to the eyes. After a long period of time, it may lead to keratitis, keratoconus and corneal tissue lesions. Even more seriously, it will become visually impaired and blind. In order to quantize the damage of rubbing eyes specifically, the research uses the porcine eyes to simulate the human eyes. To study the eyes deformation, bearing external force and the change of IOP by controlling the rubbing eyes’ depth. So that the device in static experiment can observe the IOPs, the force, the contact area, and the change of volume in the same time. The mathematic model and computer aided simulation software are also used to improve the reliability of the experiment. The mathematic model applies the small deformation based on Hertz contact theory, and the effect of eyelid and tear film are considered in it that we can get the distribution of shear stress and pressure. In addition, the device in dynamic experiment is used to simulate the true condition of eye-rubbing by using rubbing speed from human. So that the IOPs and force are observed in different rubbing depth and speed by using the artificial finger. Finally, the photoelastic method is used to analyze the stress distribution in static and dynamic test that the maximum stress can be found. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T09:21:26Z (GMT). No. of bitstreams: 1 ntu-106-R04522519-1.pdf: 6274100 bytes, checksum: 56bf118833a2d0a2827ffb11d7ca6aa0 (MD5) Previous issue date: 2017 | en |
dc.description.tableofcontents | 口試委員會審定書 ...........................................................................................................#
謝誌 ................................................................................................................................... i 中文摘要.......................................................................................................................... ii ABSTRACT .................................................................................................................... iii CONTENTS .................................................................................................................... iv LIST OF FIGURES......................................................................................................... vi LIST OF TABLES........................................................................................................... xi Chapter 1 Introduction..............................................................................................1 1.1 Background.....................................................................................................1 1.2 Literature review of eye-rubbing and keratoconus.........................................3 1.3 Motivation.......................................................................................................5 Chapter 2 Static Surface Traction on Cornea .........................................................7 2.1 Introduction.....................................................................................................7 2.2 The mathematic model ...................................................................................9 2.3 Experimental setup .......................................................................................13 2.4 The semi-sphere testing ................................................................................15 2.5 The finger testing..........................................................................................21 2.6 Discussion.....................................................................................................26 2.7 Numerical simulation....................................................................................31 Chapter 3 Dynamic Rubbing-Eye...........................................................................35 3.1 Introduction...................................................................................................35 3.2 Experimental setup, parameter tests, and results..........................................36 3.3 Discussion.....................................................................................................43 Chapter 4 Stress on Cornea ....................................................................................46 4.1 Introduction...................................................................................................46 4.2 Stress pattern testing.....................................................................................49 4.3 Discussion.....................................................................................................53 Chapter 5 Conclusion and Future work ................................................................56 REFERENCE ..................................................................................................................58 | |
dc.language.iso | zh-TW | |
dc.title | 揉眼睛動作對於眼角膜的力學分析 | zh_TW |
dc.title | Cornea stress analysis while eye-rubbing | en |
dc.type | Thesis | |
dc.date.schoolyear | 105-2 | |
dc.description.degree | 碩士 | |
dc.contributor.coadvisor | 施博仁 | |
dc.contributor.oralexamcommittee | 王一中,黃博浩,劉建豪,蔡燿全 | |
dc.subject.keyword | 揉眼睛,角膜,接觸力學,眼壓, | zh_TW |
dc.subject.keyword | eye-rubbing,cornea,IOP,Contact mechanics, | en |
dc.relation.page | 60 | |
dc.identifier.doi | 10.6342/NTU201701186 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2017-06-29 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
顯示於系所單位: | 機械工程學系 |
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