寡聚乙二醇在鈉離子存在下的辨識行為：以夾鎖法合成相關車輪烷與環連體

Abstract

第一章 本實驗室先前發表了利用固態Diels-Alder反應來合成車輪烷，進一步的希望利用不同大環分子與分子辨識單元之間的鍵結強弱與尺寸，以及封鎖基團反應性的差異，透過自我編排的方式在固態條件下進行複雜車輪烷的合成。 第二章 我們利用鈉離子模板進行寡聚乙二醇分子結構的辨識，並以夾鎖法合成相對的[2]車輪烷和[2]環連體，成功地在超分子化學領域增加了一種新的辨識系統與合成內鎖分子的方法。

Chapter 1 The efficient synthesis of asymmetrical rotaxanes with different macrocycles and stoppers remains to be a challenged task in the field of supramolecular chemistry. Recently, we report a solvent-free stoppering approach, which allows the efficient interlocking of few macrocycles in the form of [2]rotaxanes. Combining the concept of self-sorting, we plan to construct an asymmetrical [3]rotaxane, in which two macrocycles in different sizes are interlocked efficiently by their corresponding stoppers through a simple solvent-free reaction. Chapter 2 Recently, we demonstrated that the threading of oligo(ethylene glycol) units into bis-para-xylyl[26]crown-6 (BPX26C6) via Na+ ion template is possible. Herein, we reported that a macrocycle generated from a diamine and a dialdehyde can de “clipped” onto oligo(ethylene glycol) containing quests through the templating effect of a Na+ ion.