請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/54824
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 謝旭亮 | |
dc.contributor.author | Yi-Ying Lo | en |
dc.contributor.author | 羅翊郢 | zh_TW |
dc.date.accessioned | 2021-06-16T03:39:16Z | - |
dc.date.available | 2025-12-31 | |
dc.date.copyright | 2015-03-16 | |
dc.date.issued | 2015 | |
dc.date.submitted | 2015-02-24 | |
dc.identifier.citation | Alabadí, D., Gallego-Bartolomé, J., Orlando, L., García-Cárcel, L., Rubio, V., Martínez, C., Frigerio, M., Iglesias-Pedraz, J.M., Espinosa, A., Deng, X.W., and Blázquez, M.A. (2008). Gibberellins modulate light signaling pathways to prevent Arabidopsis seedling de-etiolation in darkness. Plant J. 53: 324-335.
Armstrong, G.A., Runge, S., Frick, G., Sperling, U., and Apel, K. (1995). Identification of NADPH: protochlorophyllide oxidoreductases A and B: a branched pathway for light-dependent chlorophyll biosynthesis in Arabidopsis thaliana. Plant Physiol. 108: 1505-1517. Barnes, S.A., Nishizawa, N.K., Quaggio, R.B., Whitelam, G.C., and Chua, N.H. (1996). Far-red light blocks greening of Arabidopsis seedlings via a phytochrome A-mediated change in plastid development. Plant Cell 8: 601-615. Brown, B.A., Cloix, C., Jiang, G.H., Kaisserli, E., Herzyk, P., Kliebenstein, D.J., and Jenkins, G.I. (2005). A UV-B-specific signaling component orchestrates plant UV protection. Proc. Natl. Acad. Sci. USA 102: 18225-18230. Chen, I.C., Huang, I.C., Liu, M.J., Wang, Z.G., Chung, S.S., and Hsieh, H.L. (2007). Glutathione S-transferase interacting with Far-Red Insensitive 219 is involved in phytochrome A-mediated signaling in Arabidopsis. Plant Physiol. 143: 1189-1202. Cheong, J.J., and Choi, Y.D. (2003). Methyl jasmonate as a vital substance in plants. Trends Genet. 19: 409-413. Cloix, C., Kaiserli, E., Heilmann, M., Baxter, K.J., Brown, B.A., O'Hara, A., Smith, B.O., Christie, J.M., and Jenkins, G.I. (2012). C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proc. Natl. Acad. Sci. USA 109: 16366-16370. Clough, R.C., and Vierstra, R.D. (1997). Phytochrome degradation. Plant Cell Environ. 20: 713-721. Cooley, M.B., Pathirana, S., Wu, H.J., Kachroo, P., and Klessig, D.F. (2000). Members of the Arabidopsis HRT/RPP8 family of resistance genes confer resistance to both viral and oomycete pathogens. Plant Cell 12: 663-676. De Geyter, N., Gholami, A., Goormachtig, S., and Goossens, A. (2012). Transcriptional machineries in jasmonate-elicited plant secondary metabolism. Trends Plant Sci. 17: 349-359. Deng, X.W., Minami, M., Wei, N., Wagner, D., Chu, A.M., Feldmann, K.A., and Quail, P.H. (1992). COP1, an arabidoipsis regulatory gene, encodes a protein with both a zinc-binding and a Gβ homologous domain. Cell 71: 791-801. Desnos, T., Puente, P., Whitelam, G.C., and Harberd, N.P. (2001). FHY1: a phytochrome A-specific signal transducer. Genes Dev. 15: 2980-2990. Duek, P.D., Elmer, M.V., van Oosten, V.R., and Fankhauser, C. (2004). The degradation of HFR1, a putative bHLH class transcription factor involved in light signaling, is regulated by phosphorylation and requires COP1. Curr. Biol. 14: 2296-2301. Dyachok, J., Zhu, L., Liao, F., He, J., Huq, E., and Blancaflor, E.B. (2011). SCAR mediates light-induced root elongation in Arabidopsis through photoreceptors and proteasomes. Plant Cell 23: 3610-3626. Ellis, C., and Turner, J.G. (2002). A conditionally fertile coi1 allele indicates cross-talk between plant hormone signaling pathways in Arabidopsis thaliana seeds and young seedlings. Planta 215: 549-556. Fairchild, C.D., Schumaker, M.A., and Quail, P.H. (2000). HFR1 encodes an atypical bHLH protein that acts in phytochrome A signal transduction. Gene Dev. 14: 2377-2391. Fankhauser, C., and Chory, J. (1997). Light control of plant development. Annu. Rev. Cell Dev. Biol. 13: 203-229. Favory, J.J., Stec, A., Gruber, H., Rizzini, A.O., Funk, M., Albert, A., Cloix, C., Jenkins, G.I., Oakeley, E.J., Sceidlitz, H.K., Nagy, F., and Ulm, R. (2009). Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO J. 28: 591-601. Fonseca, S., Chini, A., Hamberg, M., Adie, B., Porzel, A., Kramell, R., Miersch, O., Wasternack, C., and Solano, R. (2009). (+)-7-iso-jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate. Nat. Chem. Biol. 5: 344-350. Hiltbrunner, A., Viczian, A., Bury, E., Tscheuschler, A., Kircher, S., Toth, R., Honsberger, A., Nagy, F., Fankhauser, C., and Schafer, E. (2005). Nuclear accumulation of the phytochrome A photoreceptor requires FHY1. Curr. Biol. 15: 2125-2130. Hoecker, U., Tepperman, J.M., and Quail, P.H. (1999). SPA1, a WD-repeat protein specific to phytochrome A signal transduction. Science 284: 496-499. Holm, M., and Deng, X.W. (1999). Structural organization and interactions of COP1, a light-regulated developmental switch. Plant Mol. Biol. 41: 151-158. Holm, M., Hardtke, C.S., Gaudet, R., and Deng, X.W. (2001). Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1. EMBO J. 20: 118-127. Holm, M., Ma, L.G., Qu, L.J., and Deng, X.W. (2002). Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis. Genes Dev. 16: 1247-1259. Hsieh, H.L., and Okamoto, H. (2014). Molecular interaction of jasmonate and phytochrome A signaling. J. Exp. Bot. 65: 2847-2857. Hsieh, H.L., Okamoto, H., Wang, M., Ang, L.H., Matsui, M., Goodman, H., and Deng, X.W. (2000). FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development. Genes Dev. 14: 1958-1970. Huang, X., Ouyang, X., Yang, P., Lau, O.S., Chen, L., Wei, N., and Deng, X.W. (2013). Conversion from CUL4-based COP1–SPA E3 apparatus to UVR8–COP1–SPA complexes underlies a distinct biochemical function of COP1 under UV-B. Proc. Natl. Acad. Sci. USA 110: 16669-16674. Huang , X., Yang, P., Ouyang, X., Chen, L., and Deng, X.W. (2014). Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. PLoS Genet. 10: e1004218. Jang, I.C., Yang, J.Y., Seo, H.S., and Chua, N.H. (2005). HFR1 is targeted by COP1 E3 ligase for post-translational proteolysis during phytochrome A signaling. Genes Dev. 19: 593-602. Jefferson, R.A., Kavanagh, T.A., and Bevan, M.W. (1987). GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. EMBO J. 6: 3901-3907. Jeong, R.D., Chandra-Shekara, A.C., Barman, S.R., Navarre, D., Klessig, D.F., Kachroo, A., and Kachroo, P. (2010). Cryptochrome 2 and phototropin 2 regulate resistance protein-mediated viral defense by negatively regulating an E3 ubiquitin ligase. Proc. Natl. Acad. Sci. USA 107: 13538-13543. Jiao, Y., Lau, O.S., and Deng, X.W. (2007). Light-regulated transcriptional networks in higher plants. Nat. Rev. Genet. 8: 217-230. Kaiserli, E., and Jenkins, G.I. (2007). UV-B promotes rapid nuclear translocation of the Arabidopsis UV-B specific signaling component UVR8 and activates its function in the nucleus. Plant Cell 19: 2662-2673. Kang, C.Y., Lian, H.L., Wang, F.F., Huang, J.R., and Yang, H.Q. (2009). Cryptochromes, phytochromes, and COP1 regulate light-controlled stomatal development in Arabidopsis. Plant Cell 21: 2624-2641. Kazan, K., and Manners, J.M. (2012). JAZ repressors and the orchestration of phytohormone crosstalk. Trends Plant Sci. 17: 22-31. Kim, J., Yi, H., Choi, G., Shin, B., Song, P.S., and Choi, G. (2003). Functional characterization of Phytochrome Interacting Factor 3 in phytochrome-mediated light signal transduction. Plant Cell 15: 2399-2407. Lau, O.S., and Deng, X.W. (2012). The photomorphogenic repressors COP1 and DET1: 20 years later. Trends Plant Sci. 17: 584-593. Li, J., Li, G., Wang, H., and Deng, X.W. (2011). Phytochrome signaling mechanisms. Arabidopsis Book 9: e0148. Liu, L.J., Zhang, Y.C., Li, Q.H., Sang, Y., Mao, J., Lian, H.L., Wang, L., and Yang, H.Q. (2008). COP1-mediated ubiquitination of CONSTANS is implicated in cryptochrome regulation of flowering in Arabidopsis. Plant Cell 20: 292-306. Lorenzo, O., Chico, J.M., Sánchez-Serrano, J.J., and Solano, R. (2004). JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis. Plant Cell 16: 1938-1950. Lorenzo, O., Piqueras, R., Sanchez-Serrano, J.J., and Solano, R. (2003). ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell 15: 165-178. Luo, X.M., Lin, W.H., Zhu, S., Zhu, J.Y., Sun, Y., Fan, X.Y., Cheng, M., Hao, Y., Oh, E., Tian, M., Liu, L., Zhang, M., Xie, Q., Chong, K., and Wang, Z.Y. (2010). Integration of light- and brassinosteroid-signaling pathways by a GATA transcription factor in Arabidopsis. Dev. Cell 19: 872-883. Mathews, S., and Sharrock, R.A. (1997). Phytochrome gene diversity. Plant Cell Environ. 20: 666-671. McNellis, T.W., von Arnim, A.G., Araki, T., Komeda, Y., Mise′ra, S., and Deng, X.W. (1994a). Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional role for the multiple protein domains. Plant Cell 6: 487-500. McNellis, T.W., von Arnim, A.G., and Deng. X.W. (1994b). Overexpression of Arabidopsis COP1 results in partial suppression of light-mediated development: evidence for a light inactivable repressor of photomorphogenesis. Plant Cell 6: 1391-1400. Melotto, M., Mecey, C., Niu, Y., Chung, H.S., Katsir, L., Yao, J., Zeng, W., Thines, B., Staswick, P., Browse, J., Howe, G.A., and He, S.Y. (2008). A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein. Plant J. 55: 979-988. Moller, S.G., Ingles, P.J., and Whitelam, G.C. (2000). The cell biology of phytochrome signaling. New Phytol. 154: 553-590. Moreno, J.E., Tao, Y., Chory, J., and Ballaré, C.L. (2009). Ecological modulation of plant defense via phytochrome control of jasmonate sensitivity. Proc. Natl. Acad. Sci. USA 106: 4935-4940. Nagy, F., and Schafer, E. (2002). Phytochromes control photomorphogenesis by differentially regulated, interacting signaling pathways in higher plants. Annu. Rev. Plant Biol. 53: 329-355. Ni, M., Tepperman, J.M., and Quail, P.H. (1998). PIF3, a phytochrome-interacting factor necessary for normal photoinduced signal transduction, is a novel basic helix-loop-helix protein. Cell 95: 657-667. Oravecza, A., Baumanna, A., Mátéb, Z., Brzezinskaa, A., Molinierc, J., Oakeleyc, E.J., Ádámd, É., Schäfera, E., Nagy, F., and Ulm, R. (2006). CONSTITUTIVELY PHOTOMORPHOGENIC1 is required for the UV-B response in Arabidopsis. Plant Cell 18: 1975-1990. Osterlund, M.T., and Deng, X.W. (1998). Multiple photoreceptors mediate the light-induced reduction of GUS-COP1 from Arabidopsis hypocotyl nuclei. Plant J. 16: 201-208. Pauwels, L., Inze, D., and Goossens, A. (2009). Jasmonate-inducible gene: What does it mean? Trends Plant Sci. 14: 87-91. Peng, M., Hudson, D., Schofield, A., Tsao, R., Yang, R., Gu, H., Bi, Y.M., and Rothstein, S.J. (2008). Adaptation of Arabidopsis to nitrogen limitation involves induction of anthocyanin synthesis which is controlled by the NLA gene. J. Exp. Bot. 59: 2933-2944. Pérez, A.C., and Goossens, A. (2013). Jasmonate signalling: a copycat of auxin signalling? Plant Cell Environ. 36: 2071-2084. Porra, R.J., Thompson, W.A., and Kriedemann, P.E. (1989). Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy. Biochim. Biophys. Acta. 975: 384-394. Qi, T., Song, S., Ren, Q., Wu, D., Huang, H, Chen, Y., Fan, M., Peng, W., Ren C., and Xie, D. (2011). The Jasmonate-ZIM-Domain proteins interact with the WD-repeat/bHLH/MYB complexes to regulate jasmonate-mediated anthocyanin accumulation and trichome initiation in Arabidopsis thaliana. Plant Cell 23: 1795-1814. Quail, P.H. (2002). Phytochrome photosensory signalling networks. Nat. Rev. Mol. Cell Biol. 3: 85-93. Rafael, C., Joaquín, M., and Julio, S. (2011). Integration of low temperature and light signaling during cold acclimation response in Arabidopsis. Proc. Natl. Acad. Sci. USA 108: 16475-16480. Rizzini, L., Favory, J.J., Cloix, C., Faggionato, D., O’Hara, A., Kaiserli, E., Baumeister, R., Schäfer, E., Nagy, F., Jenkins, G.I., and Ulm, R. (2011). Perception of UV-B by the Arabidopsis UVR8 protein. Science 332: 103-106. Robson, F., Okamoto, H., Patricka, E., Harrisb, S.R., Wasternackc, C., Brearleya, C., and Turner, J.G. (2010). Jasmonate and phytochrome A signaling in Arabidopsis wound and shade responses are integrated through JAZ1 stability. Plant Cell 22: 1143-1160. Rojo, E., Titarenko, E., León, J., Berger, S., Vancanneyt, G., and Sánchez-Serrano, J.J. (1998). Reversible protein phosphorylation regulates jasmonic acid-dependent and -independent wound signal transduction pathways in Arabidopsis thaliana. Plant J. 13: 153-165. Runge, S., Sperling, U., Frick, G., Apel, K., and Armstrong, G.A. (1996). Distinct roles for light-dependent NADPH: protochlorophyllide oxidoreductases (POR) A and B during greening in higher plants. Plant J. 9: 513-523. Saijo, Y., Sullivan, J.A., Wang, H., Yang, J., Shen, Y., Rubio, V., Ma, L., Hoecker, U., and Deng, X.W. (2003). The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity. Genes Dev. 17: 2642-2647. Sassi, M., Lu, Y., Zhang, Y., Wang, F., Dhonukshe, P., Blilou, I., Dai, M., Li, J., Gong, X., Jaillais, Y., Yu, X., Traas, J., Ruberti, I., Wang, H., Scheres, B., Vernouxl, T., and Xu, J. (2012). COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1- and PIN2-dependent auxin transport in Arabidopsis. Development 139: 3402-3412. Schaller, A., and Stintzi, A. (2009). Enzymes in jasmonate biosynthesis- structure, function, regulation. Phytochemistry. 70: 1532-1538. Seo, H.S., Watanabe, E., Tokutomi, S., Nagatani, A., and Chua, N.H. (2004). Photoreceptor ubiquitination by COP1 E3 ligase desensitizes phytochrome A signaling. Genes Dev. 18: 617-622. Seo, H.S., Yang, J.Y., Ishikawa, M., Bolle, C., Ballesteros, M.L., and Chua, N.H. (2003). LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1. Nature 423: 995-999. Sheard, L.B., Tan, X., Mao, H., Withers, J., Ben-Nissan, G., Hinds, T.R., Kobayashi, Y., Hsu, F.F., Sharon, M., Browse, J., He, S.Y., Rizo, J., Howe, G.A., and Zheng, N. (2010). Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature 468: 400-405. Sheerin, D.J., Menon, C., Oven-Krockhaus, S.Z., Enderle, B., Johnen, P., Schleifenbaum, F., Stierhof, Y.D., Huq, E., and Hiltbrunner, A. (2015). Light-activated phytochrome A and B interact with members of the SPA family to promote photomorphogenesis in Arabidopsis by reorganizing the COP1/SPA complex. Advance online publication. Sibout, R., Sukumar, P., Hettiarachchi, C., Holm, M., Muday, G.K., and Hardtke, C.S. (2006). Opposite root growth phenotypes of hy5 versus hy5 hyh mutants correlate with increased constitutive auxin signaling. PLoS Genet. 2: e202. Solano, R., Stepanova, A., Chao, Q., and Ecker, J.R. (1998). Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1. Genes Dev. 12: 3703-3714. Song, S., Huang, H., Gao, H., Wang, J., Wu, D., Liu, X., Yang, S., Zhai, Q., Li, T., and Xie, D. (2014). Interaction between MYC2 and ETHYLENE INSENSITIVE3 modulates antagonism between jasmonate and ethylene signaling in Arabidopsis. Plant Cell 26: 263-279. Stacey, M.G., Hicks, S.N., and von Arnim, A. (1999). Discrete domains mediate the light-responsive nuclear and cytoplasmic localization of Arabidopsis COP1. Plant Cell 11: 349-364. Stacey, M.G., Kopp, O.R., Kim, T.H., and von Arnim, A.G. (2000). Modular domain structure of Arabidopsis COP1. Reconstitution of activity by fragment complementation and mutational analysis of a nuclear localization signal in planta. Plant Physiol. 124: 979-990. Stacey, M.G., and von Arnim, A.G. (1999). A novel motif mediates the targeting of the Arabidopsis COP1 protein to subnuclear foci. J. Biol. Chem. 17: 27231-27236. Staswick, P.E., and Tiryaki, I. (2004). The oxylipin signal jasmonic acid is activated by an enzyme that conjugates it to isoleucine in Arabidopsis. Plant Cell 16: 2117-2127. Staswick, P.E., Tiryaki, I., and Rowe, M.L. (2002). Jasmonate response locus JAR1 and several related Arabidopsis genes encode enzymes of the firefly luciferase superfamily that show activity on jasmonic, salicylic, and indole-3-acetic acids in an assay for adenylation. Plant Cell 14: 1405-1415. Subramanian, C., Kim, B.H., Lyssenko, N.N., Xu, X., Johnson, C.H., and von Arnim, A.G. (2004). The Arabidopsis repressor of light signaling, COP1, is regulated by nuclear exclusion: Mutational analysis by bioluminescence resonance energy transfer. Proc. Natl. Acad. Sci. USA 101: 6798-6802. Sullivan, J.A., and Deng, X.W. (2003). From seed to seed: the role of photoreceptors in Arabidopsis development. Dev. Biol. 260: 289-297. Thines, B., Katsir, L., Melotto, M., Niu, Y., Mandaokar, A., Liu, G., Nomura, K., He, S.Y., Howe, G.A., and Browse, J. (2007). JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling. Nature 448: 661-665. Thomma, B.P.H.J., Eggermont, K., Penninckx, I.A.M.A., Mauch-Mani, B., Vogelsang, R., Cammue, B.P.A., and Broekaert, W.F. (1998). Separate jasmonate-dependent and salicylate-dependent defense-response pathways in Arabidopsis are essential for resistance to distinct microbial pathogens. Proc. Natl. Acad. Sci. USA 95: 15107-15111. von Arnim, A.G. and Deng, X.W. (1994). Light inactivation of Arabidopsis photomorphogenic repressor COP1 involves a cell-specific regulation of its nucleocytoplasmic partitioning. Cell 79: 1035-1045. Wang, J.G., Chen, C.H., Chien, C.T., and Hsieh, H.L. (2011). FAR-RED INSENSITIVE219 modulates CONSTITUTIVE PHOTOMORPHOGENIC1 activity via physical interaction to regulate hypocotyl elongation in Arabidopsis. Plant Physiol. 156: 631-646. Wasternack, C. (2007). Jasmonates: an update on biosynthesis, signal transduction and action in plant stress response, growth and development. Ann. Bot. 100: 681-697. Wasternack, C., and Hause, B. (2002). Jasmonates and octadecanoids: signals in plant stress responses and development. Prog. Nucleic Acid Res. Mol. Biol. 72: 165-221. Wasternack, C., and Parthier, B. (1997). Jasmonate-signalled plant gene expression. Trends Plant Sci. 2: 302-307. Wu, D., Yan, Z., Chen, W., Yan, C., Huang, X., Zhang, J., Yang, P., Deng, H., Wang, J., Deng, X.W., and Shi, Y. (2012). Structural basis of ultraviolet-B perception by UVR8. Nature 484: 214-219. Xie, D.X., Feys, B., James, S., Nieto-Rostro, M., and Turner, J. (1998). COI1: An Arabidopsis gene required for jasmonate-regulated defense and fertility. Science 280: 1091-1094. Xu, D., Lin, F., Jiang, Y., Huang, X., Li, J., Ling, J., Hettiarachchi, C., Tellgren-Roth, C., Holm, M., and Deng, X.W. (2014). The RING-finger E3 ubiquitin ligase COP1 SUPPRESSOR1 negatively regulates COP1 abundance in maintaining COP1 homeostasis in dark-grown Arabidopsis seedlings. Plant Cell 26: 1981-1991. Yan, J., Zhang, C., Gu, M., Bai, Z., Zhang, W., Qi, T., Cheng, Z., Peng, W., Luo, H., Nan, F., Wang, Z., and Xie, D. (2009). The Arabidopsis CORONATINE INSENSITIVE1 protein is a jasmonate receptor. Plant Cell 21: 2220-2236. Yi, C., and Deng, X.W. (2005). COP1- from plant photomorphogenesis to mammalian tumorigenesis. Trends in Cell Biol. 15: 618-625. Yu, J.W., Rubio, V., Lee, N.Y., Bai, S., Lee, S.Y., Kim, S.S., Liu, L., Zhang, Y., Irigoyen, M.L., Sullivan, J.A., Zhang, Y., Lee, I., Xie, Q., Paek, N.C., and Deng, X.W. (2008). COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability. Mol. Cell 32: 617-630. Yu, Y., Wang, J., Zhang, Z., Quan, R., Zhang, H., Deng, X.W., Ma, L., and Huang, R. (2013). Ethylene promotes hypocotyl growth and HY5 degradation by enhancing the movement of COP1 to the nucleus in the light. PLoS Genet. 9: e1004025. Zeidler, M., Zhou, Q., Sarda, X., Yau, C.P., and Chua, N.H. (2004). The nuclear localization signal and the C-terminal region of FHY1 are required for transmission of phytochrome A signals. Plant J. 40: 355-365. Zhang, X., Zhu, Z., An, F., Hao, D., Li, P., Song, J., Yi, C., and Guo, H. (2014). Jasmonate-activated MYC2 represses ETHYLENE INSENSITIVE3 activity to antagonize ethylene-promoted apical hook formation in Arabidopsis. Plant Cell 26: 1105-1117. Zhu, Z., An, F., Feng, Y., Li, P., Xue, L., A, M., Jiang, Z., Kim, J.M., To, T.K., Li, W., Zhang, X., Yu, Q., Dong, Z., Chen, W.Q., Seki, M., Zhou, J.M., and Guo, H. (2011). Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc. Natl. Acad. Sci. USA 108: 12539-12544. Zhu, C., Gan, L., Shen, Z., and Xia, K. (2006). Interactions between jasmonates and ethylene in the regulation of root hair development in Arabidopsis. J. Exp. Bot. 57: 1299-1308. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/54824 | - |
dc.description.abstract | 植物光形態發生 (photomorphogenesis) 受光及賀爾蒙 (phytohormones) 的共同調控。先前研究指出FAR-RED INSENSITIVE 219 (FIN219) 會和CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) 進行交互作用,而COP1 在光照下會從細胞核轉移至細胞質累積;此外,即使在黑暗下,FIN219大量表現會使COP1從細胞核轉移到細胞質。FIN219/JASMONATE RESISTANT 1 (JAR1) 亦可催化 JA-isoleucine (JA-Ile) 生合成,並透過茉莉酸 (jasmonate) 訊息傳遞途徑之正調控者 CORONATINE INSENSITIVE 1 (COI1) 接收。然而,對光及茉莉酸訊息傳遞的整合研究仍未釐清透徹;另外COP1參與多種植物賀爾蒙的訊息傳遞,但是否參與在茉莉酸訊息傳遞途徑中亦是未知。故我們欲探究COP1在黑暗下的位置轉移是否透過受FIN219所調控的JA-Ile影響,並探討FIN219、COP1及COI1三者在此訊息整合中的調控關係。本研究中發現cop1-4突變體對於methyl-jasmonic acid (MeJA) 較不敏感,且COP1正調控受MeJA誘發的葉綠素生合成,並負調節花青素累積。此外,透過外表型檢測及轉錄和轉譯體表現分析得知COP1亦會參與在茉莉酸訊息傳遞途徑中,而COI1也會影響光訊息傳遞相關成員的表現。並使用共免疫沉澱法證實FIN219和COP1在黑暗下存在交互作用,且此交互作用會受到MeJA促進。另外值得注意的是MeJA的確會提升COP1在黑暗下於細胞質的累積,進而造成如光形態發生的表型。綜而言之,FIN219、COP1及COI1在光及茉莉酸訊息傳遞途徑中相輔作用,以調控植物生長發育。 | zh_TW |
dc.description.abstract | Photomorphogenic development of plants needs the integration of light and phytohormones. FAR-RED INSENSITIVE 219 (FIN219) interacted with CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) that was transferred from the nucleus to the cytoplasm in the light. Interestingly, FIN219 overexpression results in changes of COP1 subcellular localization from the nucleus to the cytoplasm even in the dark. FIN219/JASMONATE RESISTANT 1 (JAR1) catalyzes the synthesis of JA-isoleucine (JA-Ile), and JA-Ile is received by CORONATINE INSENSITIVE 1 (COI1). However, the molecular mechanism underlying the integration of light and jasmonate signaling pathways remains largely uncertain. Furthermore, COP1 has crosstalk with several phytohormones, but with jasmonate or not is still unknown. Thus, we wonder whether changes of COP1 subcellular locations from the nucleus to the cytoplasm under the dark are caused by FIN219-mediated JA-Ile. We are also interested in the relationship among FIN219, COP1 and COI1 in the integration of far-red light and jasmonate signaling. Here, we found that cop1-4 mutant is more insensitive to methyl-JA (MeJA) than Col-0. COP1 acts as a positive and a negative regulator in MeJA-promoted chlorophyll and anthocyanin accumulation, respectively. In addition, examination of phenotype, transcription and translation levels reveals that COP1 is involved in jasmonate signaling pathway and COI1 affects the protein levels of light signaling components. Furthermore, COP1 can interact with FIN219 under the dark, and this interaction is enhanced by MeJA. Strikingly, MeJA treatment can elevate the level of COP1 accumulation in the cytoplasm under the dark and result in the phenotype similar to the photomorphogenic development of seedlings. Taken together, FIN219, COP1, and COI1 coordinate far-red light and jasmonate signaling pathways, and play important roles in plant growth and development. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T03:39:16Z (GMT). No. of bitstreams: 1 ntu-104-R01b42014-1.pdf: 2834179 bytes, checksum: 008ec64a5d77a04a7b907ff21ecea678 (MD5) Previous issue date: 2015 | en |
dc.description.tableofcontents | INTRODUCTION 1
Light and Plant Photoreceptors 1 Phytochromes and FR light Signaling 2 CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) 3 FAR-RED INSENSITIVE 219 (FIN219) 5 Jasmonates and JA Synthesis 6 Jasmonate Signaling and CORNATINE INSENSITIVE1 (COI1) 7 The Crosstalk between Light and JA signaling 8 MATERIALS AND METHODS 11 Plant Materials 11 Plant Growth Conditions 11 Total Genomic DNA Isolation and Genotyping 13 Measurement of Hypocotyls and Roots 13 Chlorophyll Extraction and Quantifications 13 Anthocyanin Extraction and Quantifications 14 RNA Extraction, DNase Treatment, and Reverse Transcription 15 Total Protein Isolation and Western Blotting 15 Co-immunoprecipitation Assay 16 β-glucuronidase (GUS) Staining 17 Protoplast Isolation and Transfection 17 The Subcellular Localization of COP1 18 RESULTS 19 COP1 acts downstream of FIN219 in MeJA-mediated inhibition of hypocotyl elongation 19 COP1 positively regulates MeJA-mediated inhibition of root elongation 20 COP1 acts downstream of FIN219 and positively regulates MeJA-promoted chlorophyll synthesis in the dark and FR light. 21 COP1 negatively regulates FR light- and JA-mediated anthocyanin accumulation. 21 COP1 affects the transcript levels of JA signaling and synthesis components, especially under MeJA-treated condition. 22 COP1 is involved in jasmonate signaling pathway and COI1 affects the protein levels of light signaling components under the dark and FR light. 23 Co-immunoprecipitation assays show that there is a physical interaction between FIN219 and COP1 both in the FR light and in the dark. 25 Co-immunoprecipitation assays show that there is likely no physical interaction between FIN219 and COI1 under the dark. 25 MeJA treatment can elevate COP1 accumulation in the cytoplasm under the dark. 26 DISCUSSION 28 COP1 is involved in jasmonate signaling pathway. 28 FIN219, COP1 and COI1 participate in the network of light and jasmonate signaling pathway. 30 FIN219, COP1 and COI1 interact with each other. 32 MeJA treatment can elevate COP1 accumulation in the cytoplasm under the dark and result in a phenotype similar to photomorphogenesis. 34 Ethylene and jasmonic acid antagonistically modulate the subcellular localization of COP1. 36 Conclusions 37 FIGURES 39 Figure 1. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to different concentrations of MeJA under the dark. 39 Figure 2. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to different concentrations of MeJA under weak FR light. 40 Figure 3. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to different concentrations of MeJA under high FR light. 41 Figure 4. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to exogenous MeJA under blue light. 42 Figure 5. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to exogenous MeJA under red light. 43 Figure 6. Phenotype of wild type, fin219 and cop1 mutant seedlings in response to exogenous MeJA under white light. 44 Figure 7. COP1 acts downstream of FIN219 in MeJA-mediated inhibition of hypocotyl elongation. 45 Figure 8. COP1 positively regulates MeJA-mediated inhibition of root elongation. 46 Figure 9. COP1 acts downstream of FIN219 and positively regulates MeJA-promoted chlorophyll synthesis and negatively anthocyanin accumulation. 48 Figure 10. COP1 affects the transcript levels of JA signaling and biosynthesis components, especially under MeJA treatment. 49 Figure 11. COP1 is involved in jasmonate signaling pathway and COI1 affects the levels of light signaling components under the dark. 50 Figure 12. COP1 is involved in jasmonate signaling pathway under low FR. 51 Figure 13. Co-immunoprecipitation assays indicated physical interactions between FIN219 and COP1 under the dark with an enhancement by MeJA. 52 Figure 14. Co-immunoprecipitation assays indicated physical interactions between FIN219 and COI1 under the dark. 53 Figure 15. MeJA treatment can enrich GUS-COP1 accumulation in the cytoplasm even in the dark. 54 Figure 16. MeJA treatment can enrich ECFP-COP1 accumulation in the cytoplasm even in the dark. 56 Figure 17. A model of MeJA treatment can exclude COP1 from the nucleus to the cytoplasm under the dark. 58 Figure 18. FIN219, COP1, and COI1 coordinate far-red light and jasmonate signaling pathways in Arabidopsis. 59 TABLES 60 Table 1. The primer sequences for plant genotyping. 60 Table 2. The primer sequences for real-time PCR. 61 Table 3. The antibodies information for Western blotting. 62 REFERENCES 63 | |
dc.language.iso | en | |
dc.title | 阿拉伯芥FIN219、COP1及COI1三者在遠紅光及茉莉酸訊息傳遞途徑中之功能性探討 | zh_TW |
dc.title | Functional Studies of FIN219, COP1 and COI1 Proteins in the Integration of Far-red Light and Jasmonate Signaling in Arabidopsis | en |
dc.type | Thesis | |
dc.date.schoolyear | 103-1 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 葉開溫,鄭秋萍,吳素幸,涂世隆 | |
dc.subject.keyword | 光,茉莉酸,COP1,FIN219,COI1,阿拉伯芥幼苗發育, | zh_TW |
dc.subject.keyword | Light,Jasmonates,COP1,FIN219,COI,Arabidopsis seedling development, | en |
dc.relation.page | 75 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2015-02-24 | |
dc.contributor.author-college | 生命科學院 | zh_TW |
dc.contributor.author-dept | 植物科學研究所 | zh_TW |
顯示於系所單位: | 植物科學研究所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-104-1.pdf 目前未授權公開取用 | 2.77 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。