請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/52874完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 季瑋珠(Wei-Chu Chie) | |
| dc.contributor.author | Ya-Chi Guo | en |
| dc.contributor.author | 郭雅琦 | zh_TW |
| dc.date.accessioned | 2021-06-15T16:31:47Z | - |
| dc.date.available | 2018-09-14 | |
| dc.date.copyright | 2015-09-14 | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2015-08-13 | |
| dc.identifier.citation | 1.中華民國102年死因統計。台灣：行政院衛生署，2013。
2.台灣癌症登計年報。台灣：行政院衛生署，2011。 3.Isenring E, Bauer J, Capra S. The scored Patient generated Subjective Global Assessment (PG-SGA) and its association with quality of life in ambulatory patients receiving radiotherapy. Eur J Clin Nutr 2003;57(2):305-9. 4.Ravasco P, Monteiro-Grillo I, Vidal PM, et al. Nutritional deterioration in cancer: the role of disease and diet. Clin Oncol 2003;15:443-50. 5.Ravasco P, Monteiro-Grillo I, Vidal PM, et al. Cancer: disease and nutrition are key determinants of patients’ quality of life. Support Care Cancer 2004; 12:246-52. 6.Garth AK, Newsome CM, Simmance N, et al. Nutritional status, nutrition practices and post-operative complications in pa¬tients with gastrointestinal cancer. J Hum Nutr Diet 2010;23:393-401. 7.Segura A, Pardo J, Jara C, et al. An epidemiological evaluation of the prevalence of malnutrition in Spanish patients with locally advanced or metastatic cancer. Clin Nutr 2005;24:801-14. 8.Slaviero KA, Read JA, Clarke SJ, et al. Baseline nutritional assessment in advanced cancer patients receiving palliative chemotherapy. Nutr Cancer 2003;46:148-57. 9.凃美瑜：大腸直腸癌住院病患之營養狀況評估與飲食型態之研究。碩士論文。台南科技大學。台南2007。 10.Bozzetti F; SCRINIO Working Group. Screening the nutritional status in oncology: a preliminary report on 1,000 outpatients. Support Care Cancer 2009;17:279-84. 11.Ollenschläger G, Viell B, Thomas W, Konkol K, Bürger B. Tumor anorexia: causes, assessment, treatment. Recent Results Cancer Res 1991;121:249-59. 12.Shim H, Cheong JH, Lee KY, et al. Perioperative nutritional status changes in gastrointestinal cancer patients. Yonsei Med J 2013;54(6):1370-6. 13.Ravasco P, Monteiro- Grillo I, Vidal PM, et al. Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head Neck 2005;27:659-68. 14.Dewys WD, Begg C, Lavin PT, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern cooperative oncology group. Am J Med 1980;69:491-7. 15.Horsley P, Bauer J, Gallagher B. Poor nutritional status prior to peripheral blood stem cell transplantation is associated with increased length of hospital stay. Bone Marrow Transplant 2005;35:1113-6. 16.WHO. World Cancer Report 2014. Available at: http://apps.who.int/bookorders/anglais/detart1.jsp?codlan=1&codcol=76&codcch=31. Accessed May 26,2015. 17.Davis MP, Walsh D. Treatment of nausea and vomiting in advanced cancer. Support Care Cancer 2000;8:444-52. 18.Sun Y, Zhang B, Han Y, et al. Survey of cachexia in digestive system cancer patients and its impact on clinical outcomes. Zhonghua Wei Chang Wai Ke Za Zhi 2014;17(10):968-71. 19.Thoresen L, Frykholm G, Lydersen S, et al. Nutritional status, cachexia and survival in patients with advanced colorectal carcinoma. Different assessment criteria for nutritional status provide unequal results. Clin Nutr 2013;32(1):65-72. 20.Fearon K, Strasser F, Anker SD, et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol 2011;12:489-95. 21.謝美玲、石明煌、楊福麟：營養篩檢工具在臨床護理的應用。志為護理 2009;8:65-72。 22.Arrowsmith H. A critical evaluation of the use of nutrition screening tools by nurses. Br J Nurs 1999–2000;8:1483-90. 23.Detsky AS, McLaughlin JR, Baker JP, et al. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr 1987;11:8-13. 24.Ottery FD. Definition of standardized nutritional assessment and interventional pathways in oncology. Nutrition 1996;12:S15-9. 25.Malnutrition advisory group. BAPEN: British Association for Parenteral and Enteral Nutrition 2003. 26.Kondrup J, Allison SP, Elia M, et al. ESPEN guidelines for nutrition screening 2002. Clin Nutr 2003;22(4):415-21. 27.Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: the mini nutritional assessment as part of the geriatric evaluation. Nutr Rev 1996;54:S59-65. 28.Massa E, Madedddu C, Lusso MR, et al. Evaluation of the effectiveness of treatment with erythropoietin on anemia, cognitive functioning and functions studied by comprehensive geriatric assessment in elderly cancer patients with anemia related to cancer chemotherapy. Crit Rev Oncol Hematol 2006;57:175-82. 29.Kubrak C, Jensen L. Critical evaluation of nutrition screening tools recommended for oncology patients. Cancer Nurs 2007;30(5):E1-6. 30.Abe Vicente M, Barão K, Silva TD, et al. What are the most effective methods for assessment of nutritional status in outpatients with gastric and colorectal cancer? Nutr Hosp 2013;28(3):585-91. 31.Niezgoda H, Pater J. A validation study of the domains of the core EORTC quality of life questionnaire. Qual Life Res 1993;2:319-25. 32.Cella D, Cherin E. Quality of life during and after cancer treatment. Compr Ther 1988;14:69-75. 33.Testa MA, Simonson DC. Assessment of quality of life outcomes. N Engl J Med 1996;334:835-40. 34.Wasserman TH, McDonald A. Quality of life: The patient’s end point. Int J Radiat Oncol Biol Phys 1995;33:965-6. 35.Zhan L. Quality of life: conceptual and measurement issues. J Adv Nurs 1992;17(7):795-800. 36.The Taiwan WHOQOL Group. Introduction to the development of the WHOQOL-Taiwan version. Chinese Journal of Public Health 2000;19:315-24. 37.Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85(5):365-76. 38.Whistance RN, Conroy T, Chie W, et al. Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer. Eur J Cancer 2009;45(17):3017-26. 39.Capra S, Ferguson M, Ried K. Cancer: impact of nutrition intervention outcome – nutrition issues for patients. Nutrition 2001;17:73-80. 40.Lizdenis P, Birutis J, Čelkienė et al. Short-term results of quality of life for curatively treated colorectal cancer patients in Lithuania. Medicina (Kaunas) 2015;51(1):32-7. 41.Silander E, Nyman J, Bove M, et al. Impact of prophylactic percutaneous endoscopic gastrostomy on malnutrition and quality of life in patients with head and neck cancer: a randomized study. Head Neck 2012;34(1):1-9. 42.Ravasco P, Monteiro-Grillo I, Vidal PM, et al. Dietary Counseling Improves Patient Outcomes: A Prospective, Randomized, Controlled Trial in Colorectal Cancer Patients Undergoing Radiotherapy. J Clin Oncol 2005;23(7):1431-8. 43.Lis CG, Gupta D, Lammersfeld CA, Markman M, Vashi PG. Role of nutritional status in predicting quality of life outcomes in cancer – a systematic review of the epidemiological literature. Nutrition Journal 2012;11: 27. 44.Tian J, Chen ZC, Hang LF. The effects of nutrition status of patients with digestive system cancers on prognosis of the disease. Cancer Nurs 2008;31:462-7. 45.Andreyev HJ, Norman AR, Oates J, et al. Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies? Eur J Cancer 1998;34:503-9. 46.Ravasco P, Monteiro-Grillo I, Camilo M. Individualized nutrition intervention is of major benefit to colorectal cancer patients: long-term follow-up of a randomized controlled trial of nutritional therapy1–3. Am J Clin Nutr 2012;96:1346-53. 47.Barbosa LRLS, Lacerda-Filho A, Barbosa LCLS. Immediate preoperative nutritional status of patients with colorectal cancer: a warning. Arq Gastroenterol 2014;51(4):331-6. 48.Braga M, Ljungqvist O, Soeters P, et al. ESPEN Guidelines on Parenteral Nutrition: surgery. Clin Nutr 2009;28:378-86. 49.Weimann A, Braga M, Harsanyi L, et al. ESPEN Guidelines on Enteral Nutrition: Surgery including organ transplantation. Clin Nutr 2006;25:224-44. 50.Arends J, Bodoky G, Bozzetti F, et al. ESPEN guidelines on enteral nutrition: non-surgical oncology. Clin Nutr 2006;25:245-59. 51.O'Gorman P, McMillan DC, McArdle CS. Impact of weight loss, appetite, and the inflammatory response on quality of life in gastrointestinal cancer patients. Nutr Cancer 1998;32:76-80. 52.Gupta D, Lis CG, Granick J, et al. Malnutrition was associated with poor quality of life in colorectal cancer: a retrospective analysis. J Clin Epidemiol 2006;59:704-9. 53.Roza AM, Shizgal HM. The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass. Am J Clin Nutr 1984;40:168-82. 54.Nitenberg G, Raynard B. Nutritional support of the cancer patient: issues and dilemmas. Crit Rev Oncol Hematol 2000;34:137-68. 55.Tremblay A, Sevigny J, Leblanc C, et al. The Reproducibility of A 3-Day Dietary Record. Nutr Res 1983;3:819-30. 56.Osoba D, Rodrigues G, Myles J, et al. Interpreting the significance of changes in health-related quality-of-life scores. J. Clin. Oncol 1998;16:139-44. 57.Heo M, Impact of subject attrition on sample size determinations for longitudinal cluster randomized clinical trials. J Biopharm Stat 2014;24(3):507-22. 58.Beaver ME, Matheny KE, Roberts DB, et al. Predictors of weight loss during radiation therapy. Otolaryngol Head Neck Surg 2001;125(6):645-8. 59.許鈺喬：營養介入對台灣地區乳癌、頭頸癌、結腸直腸癌患者營養狀況及生活品質之影響。碩士論文。輔仁大學。台北 2011。 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/52874 | - |
| dc.description.abstract | 題目：個人化營養支持對於大腸直腸癌病患手術後營養狀態、生活品質之影響。
目的：藉由早期個人化之營養支持與長期追蹤、比較病患其生理指標、生活品質與營養狀態之差異，以評估營養介入之成效。 方法：本研究為前瞻性、隨機分派之對照臨床試驗研究，於2014年9月至2015年5月期間共收取84名罹患大腸直腸癌之受試者，分為營養介入組（實驗組）與常規照護組（控制組），各有42名受試者。受試者於手術治療並開始腸道進食後，經隨機分派分組行初次營養教育介入訪視並評估其營養狀態與收集生活品質相關問卷（EORTC QLQ - C30、EORTC QLQ - CR29）等，於初訪後第一個月以及第三個月進行後續資料收集，以評估個人化的營養支持對於大腸直腸癌病患後續之營養與生活品質相關成效。 結果：於營養狀態方面，營養介入組（實驗組）之第一個月與第三個月的營養狀態皆顯著優於常規照護組（控制組）；生活品質方面，在EORTC QLQ - C30問卷部份，受試者於第一個月追蹤發現其身體功能（Physical functioning）、疲勞感（Fatigue）與財務困難（Financial difficulties）等項目，營養介入組（實驗組）皆顯著優於常規照護組（控制組），於第三個月追蹤發現其身體功能（Physical functioning）、角色功能（Role functioning）、認知功能（Cognitive functioning）、疲勞感（Fatigue）、呼吸困難（Dyspnoea）、腹瀉（Diarrhoea）與財務困難（Financial difficulties）等項目，營養介入組（實驗組）皆顯著優於常規照護組（控制組）；在EORTC QLQ - CR29問卷部份，受試者於第一個月追蹤發現其血便與黏液便情形（Blood and mucus in stool）、排便頻率（Stool frequency）以及因治療而掉髮情形（Hair loss）等項目，營養介入組（實驗組）皆顯著優於常規照護組（控制組），於第三個月追蹤發現其體重（Weight）、血便與黏液便情形（Blood and mucus in stool）、解尿疼痛（Dysuria）、腹痛（Abdominal pain）與口乾（Dry mouth）等項目，營養介入組（實驗組）皆顯著優於常規照護組（控制組）。 結論：適時、適切與持續的個人化營養介入對於大腸直腸癌經手術切除病灶之受試者而言，能顯著提升攝食量而達到其自身營養需求，並能改善營養狀態與生活品質。 | zh_TW |
| dc.description.abstract | Study title: Impact of individualized nutritional support in patients with colorectal cancer after surgery.
Objectives: To investigate the impact early individualized nutritional support on long-term physiological, quality of life (QoL), and nutritional outcomes in patients with colorectal cancer after surgery. Methods: In this prospective randomized clinical trial that was carried out between September 2014 to May 2015, patients who were diagnosed colorectal cancer and underwent surgery (n=84), were randomly arranged in a 1:1 ratio to receive either individualized nutritional counseling (interventional group, n=42), or usual care (control group, n=42). Nutritional intake (diet history), status (Patient-Generated Subjective Global Assessment), and QoL (EORTC QLQ - C30, QLQ - CR29) were evaluated at baseline and after one month and three months of surgery. Results: At the one month and the three month followed ups, two groups were compared with nutritional status were significant improved in interventional group (p = 0.0352 and p < .0001). There were significant differences in EORTC QLQ - C30 scores and QLQ - CR29 scores between two groups in physical functioning (p= 0.0020), fatigue (p= 0.0002), financial difficulties (p= 0.0042), blood and mucus in stool (p< .0001), stool frequency (p= 0.0045) and hair loss (p= 0.0039) at the one month followed up. Besides, at the three months followed up, there were significant differences in EORTC QLQ - C30 scores and QLQ - CR29 scores between two groups in physical functioning (p= 0.0085), role functioning (p= 0.0043), cognitive functioning (p= 0.0062), fatigue (p= 0.0426), dyspnea (p= 0.0012), diarrhea (p= 0.0121), financial difficulties (p= 0.0331), weight (p< .0001), blood and mucus in stool (p< .0001), dysuria (p= 0.0358), abdominal pain (p= 0.0213) and dry mouth (p= 0.0002). Conclusions: Early, timely and continuous individualized nutritional intervention was the key to the improvement of nutritional outcomes and quality of life to the patients with colorectal cancer after surgery. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T16:31:47Z (GMT). No. of bitstreams: 1 ntu-104-R01847005-1.pdf: 2968644 bytes, checksum: 2b168ae291a2506470d49f6370277862 (MD5) Previous issue date: 2015 | en |
| dc.description.tableofcontents | 誌謝....................................... i
摘要....................................... ii Abstract................................... iv 目錄....................................... I 圖目錄......................................IV 表目錄.......................................V 第一章 導論.................................1 第一節 實習單位特色與簡介.....................1 第二節 研究動機..............................3 第三節 研究目的..............................4 第四節 研究族群..............................5 第二章 文獻探討..............................7 第一節 大腸直腸癌相關流行病學探討..............7 第二節 營養狀況篩檢工具.......................8 第三節 生活品質評估工具.......................10 第四節 近期相關研究...........................12 第三章 研究方法..............................15 第一節 研究設計..............................15 第二節 研究架構..............................16 第三節 研究假說..............................17 第四節 研究工具..............................17 第五節 樣本數計算............................18 第六節 隨機分派..............................18 第七節 研究變數..............................18 第八節 統計方法..............................19 第九節 倫理..................................20 第四章 研究結果..............................24 第一節 受試者基本資料描述性統計................24 第二節 受試者營養狀態指標.....................25 第三節 受試者生活品質指標.....................30 第四節 重複測量..............................39 第五章 討論..................................71 第一節 受試者營養狀態指標......................71 第二節 生活品質指標...........................74 第三節 多重比較...............................77 第四節 研究限制...............................78 第六章 結論與建議.............................79 第一節 結論..................................79 第二節 建議..................................79 參考文獻.......................................80 附錄...........................................87 附錄一 飲食回憶記錄表............................87 附錄二 食物標準份數模型與圖鑑.....................88 附錄三 Patient-Generated Subjective Global Assessment 量表.....................................90 附錄四 EORTC QLQ - C30(version 3)台灣中文版......91 附錄五 EORTC QLQ - CR29台灣中文版................93 附錄六 人體試驗委員會審查結果通知書................95 附錄七 受訪者同意書..............................96 | |
| dc.language.iso | zh-TW | |
| dc.subject | 營養 | zh_TW |
| dc.subject | 生活品質 | zh_TW |
| dc.subject | 大腸直腸癌 | zh_TW |
| dc.subject | 手術 | zh_TW |
| dc.subject | PG - SGA | zh_TW |
| dc.subject | Nutrition | en |
| dc.subject | Quality of life | en |
| dc.subject | colorectal cancer | en |
| dc.subject | PG - SGA | en |
| dc.subject | surgery | en |
| dc.title | 個人化營養支持對於大腸直腸癌病患手術後營養狀態、生活品質之影響 | zh_TW |
| dc.title | Impact of Individualized Nutritional Support in
Patients with Colorectal Cancer After Surgery | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 103-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 劉仁沛,柯威旭(Wei-Hsu Ko) | |
| dc.subject.keyword | 營養,生活品質,大腸直腸癌,手術,PG - SGA, | zh_TW |
| dc.subject.keyword | Nutrition,Quality of life,colorectal cancer,surgery,PG - SGA, | en |
| dc.relation.page | 99 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2015-08-13 | |
| dc.contributor.author-college | 公共衛生學院 | zh_TW |
| dc.contributor.author-dept | 公共衛生碩士學位學程 | zh_TW |
| 顯示於系所單位： | 公共衛生碩士學位學程 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-104-1.pdf 未授權公開取用 | 2.9 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。