請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/52575
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 鄭素芳(Suh-Fang Jeng) | |
dc.contributor.author | Yu-Han Su | en |
dc.contributor.author | 蘇郁涵 | zh_TW |
dc.date.accessioned | 2021-06-15T16:19:06Z | - |
dc.date.available | 2017-09-24 | |
dc.date.copyright | 2015-09-24 | |
dc.date.issued | 2015 | |
dc.date.submitted | 2015-08-17 | |
dc.identifier.citation | 1. Adams-Chapman, I., Hansen, N. I., Shankaran, S., Bell, E. F., Boghossian, N. S., Murray, J. C., . . . Stoll, B. J. (2013). Ten-year review of major birth defects in VLBW infants. Pediatrics, 132, 49-61.
2. Almeida, K. M., Dutra, M. V., Mello, R. R., Reis, A. B., & Martins, P. S. (2008). Concurrent validity and reliability of the Alberta Infant Motor Scale in premature infants. Jornal de Pediatría, 84, 442-448. 3. Ancel, P. Y., Livinec, F., Larroque, B., Marret, S., Arnaud, C., Pierrat, V., . . . Kaminski, M. (2006). Cerebral palsy among very preterm children in relation to gestational age and neonatal ultrasound abnormalities: the EPIPAGE cohort study. Pediatrics, 117, 828-835. 4. Bayley, N. (1993). Manual for the Bayley Scales of Infant Development (2nd ed.). San Antonio, Tx: Psychological Corporation. 5. Beck, S., Wojdyla, D., Say, L., Betran, A. P., Merialdi, M., Requejo, J. H., . . . Van Look, P. F. (2010). The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bulletin of the World Health Organization, 88, 31-38. 6. Blencowe, H., Cousens, S., Oestergaard, M. Z., Chou, D., Moller, A.-B., Narwal, R., . . . Lawn, J. E. (2012). National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet, 379, 2162-2172. 7. Boyle, C. A., Boulet, S., Schieve, L. A., Cohen, R. A., Blumberg, S. J., Yeargin-Allsopp, M., . . . Kogan, M. D. (2011). Trends in the prevalence of developmental disabilities in US children, 1997-2008. Pediatrics, 127, 1034-1042. 8. Brouwer, A., Groenendaal, F., van Haastert, I.-L., Rademaker, K., Hanlo, P., & de Vries, L. (2008). Neurodevelopmental Outcome of Preterm Infants with Severe Intraventricular Hemorrhage and Therapy for Post-Hemorrhagic Ventricular Dilatation. Journal of Pediatrics, 152, 648-654. 9. Bry, K., Lappalainen, U., Waffarn, F., Teramo, K., & Hallman, M. (1994). Influence of fetal gender on the concentration of interleukin-1 receptor antagonist in amniotic fluid and in newborn urine. Pediatric Research, 35, 130-134. 10. Cameron, E. C., Maehle, V., & Reid, J. (2005). The effects of an early physical therapy intervention for very preterm, very low birth weight infants: a randomized controlled clinical trial. Pediatric Physical Therapy, 17, 107-119. 11. Campbell, S. K., Gaebler-Spira, D., Zawacki, L., Clark, A., Boynewicz, K., deRegnier, R. A., . . . Zhou, X. J. (2012). Effects on motor development of kicking and stepping exercise in preterm infants with periventricular brain injury: a pilot study. Journal of Pediatric Rehabilitation Medicine, 5, 15-27. 12. Campos, J. J., Anderson, D. I., Barbu-Roth, M. A., Hubbard, E. M., Hertenstein, M. J., & Witherington, D. (2000). Travel Broadens the Mind. Infancy, 1, 149-219. 13. Chen, S. D., Lin, Y. C., Lu, C. L., & Chen, S. C. (2014). Changes in outcome and complication rates of very-low-birth-weight infants in one tertiary center in southern Taiwan between 2003 and 2010. Pediatrics and Neonatology, 55, 291-296. 14. Cho, J., & Holditch-Davis, D. (2014). Effects of perinatal testosterone on infant health, mother-infant interactions, and infant development. Biological Research for Nursing, 16, 228-236. 15. Constable, R. T., Ment, L. R., Vohr, B. R., Kesler, S. R., Fulbright, R. K., Lacadie, C., . . . Reiss, A. R. (2008). Prematurely born children demonstrate white matter microstructural differences at 12 years of age, relative to term control subjects: an investigation of group and gender effects. Pediatrics, 121, 306-316. 16. Cooke, R. W., Foulder-Hughes, L., Newsham, D., & Clarke, D. (2004). Ophthalmic impairment at 7 years of age in children born very preterm. Archives of Disease in Childhood: Fetal and Neonatal Edition, 89, F249-253. 17. Darrah, J., Hodge, M., Magill-Evans, J., & Kembhavi, G. (2003). Stability of serial assessments of motor and communication abilities in typically developing infants--implications for screening. Early Human Development, 72, 97-110. 18. Darrah, J., Redfern, L., Maguire, T. O., Beaulne, A. P., & Watt, J. (1998). Intra-individual stability of rate of gross motor development in full-term infants. Early Human Development, 52, 169-179. 19. Davis, N. M., Ford, G. W., Anderson, P. J., & Doyle, L. W. (2007). Developmental coordination disorder at 8 years of age in a regional cohort of extremely-low-birthweight or very preterm infants. Developmental Medicine and Child Neurology, 49, 325-330. 20. de Kieviet, J. F., Piek, J. P., Aarnoudse-Moens, C. S., & Oosterlaan, J. (2009). Motor development in very preterm and very low-birth-weight children from birth to adolescence: a meta-analysis. Journal of the American Medical Association, 302, 2235-2242. 21. Delucchi, K. L., Matzger, H., & Weisner, C. (2004). Dependent and problem drinking over 5 years: a latent class growth analysis. Drug and Alcohol Dependence, 74, 235-244. 22. Duncan, A. F., Watterberg, K. L., Nolen, T. L., Vohr, B. R., Adams-Chapman, I., Das, A., & Lowe, J. (2012). Effect of ethnicity and race on cognitive and language testing at age 18-22 months in extremely preterm infants. Journal of Pediatrics, 160, 966-971.e962. 23. Erikson, C., Allert, C., Carlberg, E. B., & Katz-Salamon, M. (2003). Stability of longitudinal motor development in very low birthweight infants from 5 months to 5.5 years. Acta Paediatrica, 92, 197-203. 24. Gaddlin, P. O., Finnstrom, O., Samuelsson, S., Wadsby, M., Wang, C., & Leijon, I. (2008). Academic achievement, behavioural outcomes and MRI findings at 15 years of age in very low birthweight children. Acta Paediatrica, 97, 1426-1432. 25. Goyen, T. A., & Lui, K. (2009). Developmental coordination disorder in 'apparently normal' schoolchildren born extremely preterm. Archives of Disease in Childhood, 94, 298-302. 26. Goyen, T. A., Todd, D. A., Veddovi, M., Wright, A. L., Flaherty, M., & Kennedy, J. (2006). Eye-hand co-ordination skills in very preterm infants <29 weeks gestation at 3 years: Effects of preterm birth and retinopathy of prematurity. Early Human Development, 82, 739-745. 27. Greenbaum, P. E., Del Boca, F. K., Darkes, J., Wang, C. P., & Goldman, M. S. (2005). Variation in the drinking trajectories of freshmen college students. Journal of Consulting and Clinical Psychology, 73, 229-238. 28. Grisaru-Granovsky, S., Reichman, B., Lerner-Geva, L., Boyko, V., Hammerman, C., Samueloff, A., & Schimmel, M. S. (2014). Population-based trends in mortality and neonatal morbidities among singleton, very preterm, very low birth weight infants over 16 years. Early Human Development, 90, 821-827. 29. Hintz, S. R., Kendrick, D. E., Vohr, B. R., Kenneth Poole, W., & Higgins, R. D. (2006). Gender differences in neurodevelopmental outcomes among extremely preterm, extremely-low-birthweight infants. Acta Paediatrica, 95, 1239-1248. 30. Horbar, J. D., Carpenter, J. H., Badger, G. J., Kenny, M. J., Soll, R. F., Morrow, K. A., & Buzas, J. S. (2012). Mortality and neonatal morbidity among infants 501 to 1500 grams from 2000 to 2009. Pediatrics, 129, 1019-1026. 31. Hsu, J. F., Tsai, M. H., Chu, S. M., Fu, R. H., Chiang, M. C., Hwang, F. M., . . . Huang, Y. S. (2013). Early detection of minor neurodevelopmental dysfunctions at age 6 months in prematurely born neonates. Early Human Development, 89, 87-93. 32. Imamura, T., Ariga, H., Kaneko, M., Watanabe, M., Shibukawa, Y., Fukuda, Y., . . . Fujiki, T. (2013). Neurodevelopmental outcomes of children with periventricular leukomalacia. Pediatrics and Neonatology, 54, 367-372. 33. Inder, T. E., Wells, S. J., Mogridge, N. B., Spencer, C., & Volpe, J. J. (2003). Defining the nature of the cerebral abnormalities in the premature infant: a qualitative magnetic resonance imaging study. Journal of Pediatrics, 143, 171-179. 34. International Committee for the Classification of Retinopathy of Prematurity (2005). The International Classification of Retinopathy of Prematurity revisited. Archives of Ophthalmology, 123, 991-999. 35. Isayama, T., Lee, S. K., Mori, R., Kusuda, S., Fujimura, M., Ye, X. Y., & Shah, P. S. (2012). Comparison of mortality and morbidity of very low birth weight infants between Canada and Japan. Pediatrics, 130, e957-965. 36. Janssen, A. J., Akkermans, R. P., Steiner, K., de Haes, O. A., Oostendorp, R. A., Kollee, L. A., & Nijhuis-van der Sanden, M. W. (2011). Unstable longitudinal motor performance in preterm infants from 6 to 24 months on the Bayley Scales of Infant Development--Second edition. Research in Developmental Disabilities, 32, 1902-1909. 37. Jeng, S. F., & Hsieh, W. S. (2004). Predictive Ability of Early Neuromotor Examinations on Walking Attainment in Very-Low-Birth-Weight infants at 18 Months Corrected Age. Formosan Journal of Physical Therapy, 29, 9-20. 38. Jeng, S. F., Hsu, C. H., Tsao, P. N., Chou, H. C., Lee, W. T., Kao, H. A., . . . Hsieh, W. S. (2008). Bronchopulmonary dysplasia predicts adverse developmental and clinical outcomes in very-low-birthweight infants. Developmental Medicine and Child Neurology, 50, 51-57. 39. Jeng, S. F., Yau, K. I., Chen, L. C., & Hsiao, S. F. (2000). Alberta infant motor scale: reliability and validity when used on preterm infants in Taiwan. Physical Therapy, 80, 168-178. 40. Jeng, S. F., Yau, K. I., Liao, H. F., Chen, L. C., & Chen, P. S. (2000). Prognostic factors for walking attainment in very low-birthweight preterm infants. Early Human Development, 59, 159-173. 41. Jobe, A. H., & Bancalari, E. (2001). Bronchopulmonary dysplasia. American Journal of Respiratory and Critical Care Medicine, 163, 1723-1729. 42. Johnson, S., & Marlow, N. (2006). Developmental screen or developmental testing? Early Human Development, 82, 173-183. 43. Jung, T., & Wickrama, K. A. S. (2008). An Introduction to Latent Class Growth Analysis and Growth Mixture Modeling. Social and Personality Psychology Compass, 2, 302-317. 44. Katz-Salamon, M., Gerner, E. M., Jonsson, B., & Lagercrantz, H. (2000). Early motor and mental development in very preterm infants with chronic lung disease. Archives of Disease in Childhood: Fetal and Neonatal Edition, 83, F1-6. 45. Kidokoro, H., Anderson, P. J., Doyle, L. W., Woodward, L. J., Neil, J. J., & Inder, T. E. (2014). Brain injury and altered brain growth in preterm infants: predictors and prognosis. Pediatrics, 134, e444-453. 46. Kono, Y., Mishina, J., Sato, N., Watanabe, T., & Honma, Y. (2008). Developmental characteristics of very low-birthweight infants at 18 months' corrected age according to birthweight. Pediatrics International, 50, 23-28. 47. Kusuda, S., Fujimura, M., Uchiyama, A., Totsu, S., & Matsunami, K. (2012). Trends in morbidity and mortality among very-low-birth-weight infants from 2003 to 2008 in Japan. Pediatric Research, 72, 531-538. 48. Landry, J. S., Chan, T., Lands, L., & Menzies, D. (2011). Long-term impact of bronchopulmonary dysplasia on pulmonary function. Canadian Respiratory Journal, 18, 265-270. 49. Laursen, B., & Hoff, E. (2006). Person-Centered and Variable-Centered Approaches to Longitudinal Data. Merrill-Palmer Quarterly, 52, 377-389. 50. LeCouffe, N. E., Westerbeek, E. A., van Schie, P. E., Schaaf, V. A., Lafeber, H. N., & van Elburg, R. M. (2014). Neurodevelopmental outcome during the first year of life in preterm infants after supplementation of a prebiotic mixture in the neonatal period: a follow-up study. Neuropediatrics, 45, 22-29. 51. Lekskulchai, R., & Cole, J. (2001). Effect of a developmental program on motor performance in infants born preterm. Australian Journal of Physiotherapy, 47, 169-176. 52. Leversen, K. T., Sommerfelt, K., Ronnestad, A., Kaaresen, P. I., Farstad, T., Skranes, J., . . . Markestad, T. (2011). Prediction of neurodevelopmental and sensory outcome at 5 years in Norwegian children born extremely preterm. Pediatrics, 127, e630-638. 53. Majnemer, A., Riley, P., Shevell, M., Birnbaum, R., Greenstone, H., & Coates, A. L. (2000). Severe bronchopulmonary dysplasia increases risk for later neurological and motor sequelae in preterm survivors. Developmental Medicine and Child Neurology, 42, 53-60. 54. Mansson, J., Fellman, V., & Stjernqvist, K. (2015). Extremely preterm birth affects boys more and socio-economic and neonatal variables pose sex-specific risks. Acta Paediatrica, 104, 514-521. 55. Marin Gabriel, M. A., Pallas Alonso, C. R., De La Cruz Bertolo, J., Caserio Carbonero, S., Lopez Maestro, M., Moral Pumarega, M., . . . Lora Pablos, D. (2009). Age of sitting unsupported and independent walking in very low birth weight preterm infants with normal motor development at 2 years. Acta Paediatrica, 98, 1815-1821. 56. Munck, P., Haataja, L., Maunu, J., Parkkola, R., Rikalainen, H., Lapinleimu, H., & Lehtonen, L. (2010). Cognitive outcome at 2 years of age in Finnish infants with very low birth weight born between 2001 and 2006. Acta Paediatrica, 99, 359-366. 57. Nagin, D. (2005). Group-based modeling of development. London: Harvard University Press. 58. Nuysink, J., van Haastert, I. C., Eijsermans, M. J., Koopman-Esseboom, C., Helders, P. J., de Vries, L. S., & van der Net, J. (2013). Prediction of gross motor development and independent walking in infants born very preterm using the Test of Infant Motor Performance and the Alberta Infant Motor Scale. Early Human Development, 89, 693-697. 59. Nylund, K. L., Asparouhov, T., & Muthén, B. O. (2007). Deciding on the Number of Classes in Latent Class Analysis and Growth Mixture Modeling: A Monte Carlo Simulation Study. Structural Equation Modeling: A Multidisciplinary Journal, 14, 535-569. 60. Ohlsson, A., & Jacobs, S. E. (2013). NIDCAP: a systematic review and meta-analyses of randomized controlled trials. Pediatrics, 131, e881-893. 61. Ong, L. C., Boo, N. Y., & Chandran, V. (2001). Predictors of neurodevelopmental outcome of Malaysian very low birthweight children at 4 years of age. Journal of Paediatrics and Child Health, 37, 363-368. 62. Ortinau, C., & Neil, J. (2014). The neuroanatomy of prematurity: Normal brain development and the impact of preterm birth. Clinical Anatomy, 28, 168-183. 63. Peacock, J. L., Marston, L., Marlow, N., Calvert, S. A., & Greenough, A. (2012). Neonatal and infant outcome in boys and girls born very prematurely. Pediatric Research, 71, 305-310. 64. Pin, T. W., de Valle, K., Eldridge, B., & Galea, M. P. (2010). Clinimetric properties of the alberta infant motor scale in infants born preterm. Pediatric Physical Therapy, 22, 278-286. 65. Pin, T. W., Eldridge, B., & Galea, M. P. (2010). Motor trajectories from 4 to 18 months corrected age in infants born at less than 30 weeks of gestation. Early Human Development, 86, 573-580. 66. Piper, M. C., & Darrah, J. (1994). Motor assessment of the developing infant. Philadelphia: Saunders. 67. Rüegger, C., Hegglin, M., Adams, M., & Bucher, H. U. (2012). Population based trends in mortality, morbidity and treatment for very preterm- and very low birth weight infants over 12 years. BMC Pediatrics, 12. 68. Ram, N., & Grimm, K. J. (2009). Growth Mixture Modeling: A Method for Identifying Differences in Longitudinal Change Among Unobserved Groups. International Journal of Behavioral Development, 33, 565-576. 69. Saigal, S., den Ouden, L., Wolke, D., Hoult, L., Paneth, N., Streiner, D. L., . . . Pinto-Martin, J. (2003). School-age outcomes in children who were extremely low birth weight from four international population-based cohorts. Pediatrics, 112, 943-950. 70. Sari, F. N., Eras, Z., Dizdar, E. A., Erdeve, O., Oguz, S. S., Uras, N., & Dilmen, U. (2012). Do oral probiotics affect growth and neurodevelopmental outcomes in very low-birth-weight preterm infants? American Journal of Perinatology, 29, 579-586. 71. Short, E. J., Klein, N. K., Lewis, B. A., Fulton, S., Eisengart, S., Kercsmar, C., . . . Singer, L. T. (2003). Cognitive and academic consequences of bronchopulmonary dysplasia and very low birth weight: 8-year-old outcomes. Pediatrics, 112, e359. 72. Spittle, A., Orton, J., Anderson, P., Boyd, R., & Doyle, L. W. (2012). Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants. Cochrane Database of Systematic Reviews, 12, CD005495. 73. Spittle, A. J., Doyle, L. W., & Boyd, R. N. (2008). A systematic review of the clinimetric properties of neuromotor assessments for preterm infants during the first year of life. Developmental Medicine and Child Neurology, 50, 254-266. 74. Spittle, A. J., Spencer-Smith, M. M., Cheong, J. L., Eeles, A. L., Lee, K. J., Anderson, P. J., & Doyle, L. W. (2013). General movements in very preterm children and neurodevelopment at 2 and 4 years. Pediatrics, 132, e452-458. 75. Stoelhorst, G. M., Rijken, M., Martens, S. E., van Zwieten, P. H., Feenstra, J., Zwinderman, A. H., . . . Veen, S. (2003). Developmental outcome at 18 and 24 months of age in very preterm children: a cohort study from 1996 to 1997. Early Human Development, 72, 83-95. 76. Stoinska, B., & Gadzinowski, J. (2011). Neurological and developmental disabilities in ELBW and VLBW: follow-up at 2 years of age. Journal of Perinatology, 31, 137-142. 77. Symington, A., & Pinelli, J. (2006). Developmental care for promoting development and preventing morbidity in preterm infants. Cochrane Database of Systematic Reviews, 19, CD001814. 78. Taylor, H. G., Klein, N., Minich, N. M., & Hack, M. (2000). Middle-school-age outcomes in children with very low birthweight. Child Development, 71, 1495-1511. 79. Tu, Y.-K., & Greenwood, D. C. (2012). Modern methods for epidemiology. New York: Springer. 80. van Haastert, I. C., de Vries, L. S., Helders, P. J., & Jongmans, M. J. (2006). Early gross motor development of preterm infants according to the Alberta Infant Motor Scale. Journal of Pediatrics, 149, 617-622. 81. Van Hus, J. W., Jeukens-Visser, M., Koldewijn, K., Geldof, C. J., Kok, J. H., Nollet, F., & Van Wassenaer-Leemhuis, A. G. (2013). Sustained developmental effects of the infant behavioral assessment and intervention program in very low birth weight infants at 5.5 years corrected age. Journal of Pediatrics, 162, 1112-1119. 82. Van Hus, J. W., Jeukens-Visser, M., Koldewijn, K., Van Sonderen, L., Kok, J. H., Nollet, F., & Van Wassenaer-Leemhuis, A. G. (2013). Comparing two motor assessment tools to evaluate neurobehavioral intervention effects in infants with very low birth weight at 1 year. Physical Therapy, 93, 1475-1483. 83. Van Hus, J. W., Potharst, E. S., Jeukens-Visser, M., Kok, J. H., & Van Wassenaer-Leemhuis, A. G. (2014). Motor impairment in very preterm-born children: links with other developmental deficits at 5 years of age. Developmental Medicine and Child Neurology, 56, 587-594. 84. Van Naarden Braun, K., Christensen, D., Doernberg, N., Schieve, L., Rice, C., Wiggins, L., . . . Yeargin-Allsopp, M. (2015). Trends in the prevalence of autism spectrum disorder, cerebral palsy, hearing loss, intellectual disability, and vision impairment, metropolitan atlanta, 1991-2010. PLoS One, 10, e0124120. 85. Verkerk, G., Jeukens-Visser, M., van Wassenaer-Leemhuis, A., Kok, J., & Nollet, F. (2014). The relationship between multiple developmental difficulties in very low birth weight children at 3(1/2) years of age and the need for learning support at 5 years of age. Research in Developmental Disabilities, 35, 185-191. 86. Vohr, B. R., Wright, L. L., Dusick, A. M., Mele, L., Verter, J., Steichen, J. J., . . . Kaplan, M. D. (2000). Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994. Pediatrics, 105, 1216-1226. 87. Wang, C. J., McGlynn, E. A., Brook, R. H., Leonard, C. H., Piecuch, R. E., Hsueh, S. I., & Schuster, M. A. (2006). Quality-of-care indicators for the neurodevelopmental follow-up of very low birth weight children: results of an expert panel process. Pediatrics, 117, 2080-2092. 88. Wang, M., & Bodner, T. E. (2007). Growth Mixture Modeling: Identifying and Predicting Unobserved Subpopulations With Longitudinal Data. Organizational Research Methods, 10, 635-656. 89. Wild, K. T., Betancourt, L. M., Brodsky, N. L., & Hurt, H. (2013). The effect of socioeconomic status on the language outcome of preterm infants at toddler age. Early Human Development, 89, 743-746. 90. Wood, N. S., Costeloe, K., Gibson, A. T., Hennessy, E. M., Marlow, N., & Wilkinson, A. R. (2005). The EPICure study: associations and antecedents of neurological and developmental disability at 30 months of age following extremely preterm birth. Archives of Disease in Childhood: Fetal and Neonatal Edition, 90, F134-140. 91. Wu, Y. C., Leng, C. H., Hsieh, W. S., Hsu, C. H., Chen, W. J., Gau, S. S., . . . Jeng, S. F. (2014). A randomized controlled trial of clinic-based and home-based interventions in comparison with usual care for preterm infants: effects and mediators. Research in Developmental Disabilities, 35, 2384-2393. 92. Wu, Y. T., Tsou, K. I., Hsu, C. H., Fang, L. J., Yao, G., & Jeng, S. F. (2008). Brief report: Taiwanese infants' mental and motor development--6-24 months. Journal of Pediatric Psychology, 33, 102-108. 93. Zwicker, J. G., Yoon, S. W., Mackay, M., Petrie-Thomas, J., Rogers, M., & Synnes, A. R. (2013). Perinatal and neonatal predictors of developmental coordination disorder in very low birthweight children. Archives of Disease in Childhood, 98, 118-122. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/52575 | - |
dc.description.abstract | 背景與目的:極低出生體重早產兒(出生體重<1,500公克)為動作發展遲緩的高危險族群極需早期評估與介入。過去探討早產兒早期動作發展之文獻多為單一時間點的評估並顯示群體平均的表現,少有探討可能出現次群體之動作發展變化及影響動作發展軌跡的因子。因此,本研究之目的為探究極低出生體重早產兒一歲以前之粗動作發展軌跡、其影響因子以及與日後發展之關聯。方法:本研究包括342位極低出生體重早產兒,收集其周產期與社會環境資料,並於矯正年齡4、6、9及12個月時實施阿爾伯塔嬰幼兒動作量表評估以了解其粗動作發展,及矯正年齡兩歲時實施貝萊氏嬰兒發展量表第二版之評估以了解其神經發展預後。結果:極低出生體重早產兒呈現三種粗動作發展軌跡:持續正常(55%)、逐漸變差(32%)及持續遲緩(13%)。逐漸變差軌跡與低出生體重(勝算比[95%信賴區間] = 1.1 [1.0-1.1])、男孩(勝算比[95%信賴區間] = 2.4 [1.4-3.8])、中重度慢性肺疾病(勝算比[95%信賴區間] = 2.9 [1.7-5.0])明顯相關;持續遲緩軌跡與低出生體重(勝算比[95%信賴區間] = 1.1 [1.0-1.1])、中重度慢性肺疾病(勝算比[95%信賴區間] = 5.1 [2.3-11.4])、第三四度視網膜病變(勝算比[95%信賴區間] = 7.2 [2.6-19.9])及嚴重腦傷(勝算比[95%信賴區間] = 51.5 [6.3-423.4])明顯相關(以上p < 0.05)。此外,逐漸變差軌跡可預測矯正年齡兩歲之動作遲緩(邊緣遲緩勝算比[95%信賴區間] = 3.2 [1.8-5.7]與顯著遲緩勝算比[95%信賴區間] = 20.6 [4.6-92.0])以及認知遲緩(邊緣遲緩勝算比[95%信賴區間] = 2.4 [1.4-4.3]與顯著遲緩勝算比[95%信賴區間] = 6.6 [2.1-20.8)]),而持續遲緩軌跡則可預測矯正年齡兩歲之動作遲緩(邊緣遲緩勝算比[95%信賴區間] = 8.0 [3.3-19.4]與顯著遲緩勝算比[95%信賴區間] = 83.4 [16.1-432.7])以及認知遲緩(邊緣遲緩勝算比[95%信賴區間] = 7.6 [3.0-18.9]與顯著遲緩勝算比[95%信賴區間] = 28.5 [7.8-103.5]) (以上p < 0.05)。結論:極低出生體重早產兒於一歲前之動作發展呈現多樣的軌跡,主要與周產期因子相關,並可預測矯正年齡兩歲之認知與動作發展預後。以上資料可提供早期偵測早產兒動作發展遲緩及接受早期介入之參考。 | zh_TW |
dc.description.abstract | Background and Purposes: Preterm infants with very low birth weight (VLBW, birth weight < 1,500g) are at risk of motor disorders that require early assessment and intervention. Previous studies on early motor development in preterm infants were mostly based on single time point and have relied on estimation of mean performance that the variation within group over age and the influencing factors were rarely explored. Therefore, the purposes of this study were to examine the developmental trajectories of gross motor function in VLBW preterm infants during the first year of life, to investigate the influencing factors for the motor trajectories, and to investigate the prediction of later neurodevelopmental outcome by early motor trajectories. Methods: A total of 342 VLBW preterm infants were prospectively assessed for their motor function by the Alberta Infant Motor Scales (AIMS) at 4, 6, 9 and 12 months of corrected age, and were examined for the cognitive and motor function by the Bayley Scales of Infant and Toddler Development-2nd edition (BSID-II) at two years of corrected age. Perinatal and socio-environmental factors were also collected. Results: VLBW preterm infants showed three distinct motor developmental trajectories during the first year of life: stably normal (55%), deteriorating (32%), and persistently delayed (13%). The deteriorating pattern was significantly associated with low birth body weight (odds ratio (OR) [95% confidence interval (CI)] = 1.1 [1.0-1.1]), male gender (OR [95% CI]= 2.4 [1.4-3.8]), and moderate/severe bronchopulmonary dysplasia (OR [95% CI]= 2.9 [1.7-5.0]); whereas the persistently delayed pattern was significantly associated with low birth body weight (OR [95% CI]= 1.1 [1.0-1.1]), moderate/severe bronchopulmonary dysplasia (OR [95% CI] = 5.1 [2.3-11.4]), stage III/IV retinopathy of prematurity (OR [95% CI] = 7.2 [2.6-19.9]), and major brain damage (OR [95% CI] = 51.5 [6.3-423.4]) (all p < 0.05). Furthermore, the deteriorating pattern was predictive of motor delay (borderline delay, OR [95% CI] = 3.2 [1.8-5.7]; significant delay, OR [95% CI] = 20.6 [4.6-92.0]) and mental delay (borderline delay, OR [95% CI] = 2.4 [1.4-4.3]; significant delay, OR [95% CI] = 6.6 [2.1-20.8]) at two years of corrected age; whereas the persistently delayed pattern was predictive of motor delay (borderline delay, OR [95% CI] = 8.0 [3.3-19.4]; significant delay, OR [95% CI] = 83.4 [16.1-432.7]) and mental delay (borderline delay, OR [95% CI] = 7.6 [3.0-18.9]; significant delay, OR [95% CI] = 28.5 [7.8-103.5]) at two years of corrected age (all p < 0.05). Conclusion: VLBW preterm infants manifested various motor trajectories throughout the first year of life that were mainly related to perinatal factors and were predictive of later motor and mental outcome. The results provided insightful information for early detection and intervention of motor disorders in VLBW preterm infants. | en |
dc.description.provenance | Made available in DSpace on 2021-06-15T16:19:06Z (GMT). No. of bitstreams: 1 ntu-104-R02428002-1.pdf: 1322861 bytes, checksum: 618ea3e617be2653ce439db8212a568d (MD5) Previous issue date: 2015 | en |
dc.description.tableofcontents | 誌謝……………………………………………………………………………………i
口試委員會審定書……………………………………………………………………ii 摘要………………………………………………………………………………………iii Abstract…………………………………………………………………………………v Contents…………………………………………………………………………………vii Chapter I. Introduction……………………………………………………………………1 1.1 Lifelong consequences of preterm birth with VLBW……………………………1 1.2 Early motor development in VLBW preterm infants……………………………2 1.3 Early assessment of motor function in preterm children…………………………3 1.4 Statistical methods for assessment of motor trajectory patterns…………………3 1.5 Influencing factors for motor development………………………………………5 1.6 Study purposes and hypotheses……………………………………………………7 Chapter II. Method……………………………………………………………………9 2.1 Participants………………………………………………………………………9 2.2 Assessment procedures……………………………………………………………9 2.3 Neurodevelopmental measures……………………………………………………10 2.3.1 Alberta Infant Motor Scale……………………………………………………10 2.3.2 Bayley Scales of Infant and Toddler Development-2nd Edition……………11 2.4 Statistical analysis………………………………………………………………13 Chapter III. Results……………………………………………………………………17 3.1 Study Sample……………………………………………………………………17 3.2 Gross motor development at 4, 6, 9, and 12 months of age………………………17 3.3 Model selection for motor trajectories……………………………………………18 3.4 Developmental trajectories of gross motor function in VLBW infants……………19 3.5 Influencing factors associated with motor trajectories during the first year of life………………………………………………………………………………………20 3.6 Prediction of neurodevelopmental outcome at two years of corrected age from motor trajectories during the first year of life…………………………………………21 Chapter IV. Discussion……………………………………………………………….22 Chapter V. Conclusion…………………………………………………………………27 Chapter VI. Acknowledgement………………………………………………………28 Tables and Figures……………………………………………………………………29 References……………………………………………………………………………42 Appendix………………………………………………………………………………55 | |
dc.language.iso | en | |
dc.title | 極低出生體重早產兒於一歲前之粗動作發展軌跡 | zh_TW |
dc.title | Trajectories of Gross Motor Function in Very-Low-Birth-Weight Preterm Infants during the First Year of Life | en |
dc.type | Thesis | |
dc.date.schoolyear | 103-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 吳晏慈(Yen-Tzu Wu),杜裕康(Yu-Kang Tu),陳麗秋(Li-Chiou Chen),謝武勳(Wu-Shiun Hsieh) | |
dc.subject.keyword | 早產兒,嬰兒期,動作發展,軌跡,危險因子,預後, | zh_TW |
dc.subject.keyword | preterm infants,infancy,motor development,trajectories,influencing factors,prediction, | en |
dc.relation.page | 63 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2015-08-17 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 物理治療學研究所 | zh_TW |
顯示於系所單位: | 物理治療學系所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-104-1.pdf 目前未授權公開取用 | 1.29 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。