請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51955
標題: | 藥用植物抗氧化力與黃嘌呤氧化酶抑制效果之探討 Antioxidant activities and xanthine oxidase inhibitory effects of medicinal plants |
作者: | Yu-Wen Lin 林郁雯 |
指導教授: | 黃文達(Wen-Dar Huang) |
共同指導教授: | 楊棋明(Chi-Ming Yang) |
關鍵字: | 藥用植物,色素,次級代謝物,保健功效,抗氧化力, medicinal plants,pigments,secondary metabolites,health effects,antioxidant capacity, |
出版年 : | 2015 |
學位: | 碩士 |
摘要: | 隨著國人經濟水準提昇,飲食習慣改變以及運動量降低,慢性病盛行率大幅提高,對身體保健愈來愈受重視。天然藥用植物在過去被各民族用在治療疾病上,而現今許多西藥及保健食品都是從當中萃取活性成分純化或再經修飾而得。然現今雖已有針對一些已知藥用植物進行研究,但仍有許多藥用植物其保健功效尚未被討論或研究。本研究以本土具有保健潛力之藥用植物:檄樹(Morinda citrifolia L.)、破布子(Cordia dichotoma Frost. f.)、紫蘇(Perilla frutescens)、柑橘類果皮為材料,測定其色素與次級代謝物含量以及螯合亞鐵離子能力、清除DPPH自由基能力、還原能力及抑制黃嘌呤氧化酶能力等四種保健功能性測定進行關聯性分析及灰關聯分析。研究結果顯示紫蘇葉為乙醇浸泡萃取方式之最佳具抗氧化潛力的植物材料,且所有代謝物含量上皆為最高。由於浸泡液長時間貯放之故,所以酚類、類黃酮及花青素含量會減少,葉綠素的多寡成為保健功效的關鍵,其中灰關聯分析指出葉綠素a、總葉綠素及葉綠素b是影響抗氧化力最密切的植物代謝物。以植物材料植株部位而言,葉子由於富含葉綠素,因此檄樹葉及破布子葉也具有相當之潛力。另外,以柚果實不同部位去分析,得到柑橘類果實的果皮是保健功效的關鍵,進一步分析其他柑橘類果皮,發現橘子皮及檸檬皮之保健功效僅次於紫蘇葉,這可能與柑橘類果皮具許多種重要酚類及類黃酮化合物有關,因此才能擁有較好的抗氧化能力。總歸而言,在乙醇浸泡萃取物中,篩選得到了紫蘇葉、橘子皮、檸檬皮與檄樹葉等具有進一步研究潛力之植物材料,且亦有良好的保健功效,其中橘子皮、檸檬皮之應用可以解決了一些農業廢棄物問題,增加其附加價值。本研究結果可供未來醫學與食品保健研究參考,以進一步分析這些藥用植物關鍵保健成分。 With the economy standards improved, people in Taiwan have changed in eating habits and decreased physical activity, so there is a substantial increase in the prevalence of chronic diseases. It is increasingly starting to pay attention to health care. Natural medicinal plants used in the past by various ethnic groups in the treatment of disease, and many of today's medicine and health food are extracted from the active ingredient purified or re-modified derived of natural medicinal plants. Although the current study have known for a number of medicinal plants, but there are still a lot of medicinal plants whose health benefits have not yet been discussed or studied. In this study, with the health potential of local medicinal plants: noni tree (Morinda citrifolia L.), cummingcordia (Cordia dichotoma Frost f), perilla (Perilla frutescens), and citrus peels as plant material, measured pigment and secondary metabolite contents, and four kinds of health functional assay: ferrous ion chelating ability, DPPH radical scavenging, reducing power and xanthine oxidase inhibition activity, and do the correlation and grey relational analysis. Our results show that the potential ethanol extracts is perilla leaves, it is the best plant material of antioxidant activities and the supreme all metabolites content. Due to prolonged soaking solvent storage, therefore, phenols, flavonoids and anthocyanin content reduced, the amount of chlorophyll becomes critical antioxidant capacity. In the result of grey relational analysis, chlorophyll a, total chlorophyll and chlorophyll b are the greatest impact plant metabolites for antioxidant capacity. The metabolite content and antioxidant capacity of leaves will be better than other parts due to leaves rich in chlorophyll, so leaves of noni and cummingcordia therefore also become quite potential. Analysis in different parts of the pomelo fruit, we can get the key of health effects in citrus fruits is peels. Further analysis in other kinds of citus peels, we find the health effects of mandarin peels and lemon peels just behind perilla leaves, which may be due to the many important phenols and flavonoids in citrus peels. In conclusion, in the ethanol extracts, we get these plant materials: perilla leaves, mandarin peels, lemon peels, and noni leaves having the potential in further study, and also having good health benefits. Moreover, the applications of mandarin peels, lemon peels can solve some problems of agricultural waste and increase their added value. The results of this study can give some information for further analysis of medicine, food, health care research to find the key health ingredients in these medicinal plants. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51955 |
全文授權: | 有償授權 |
顯示於系所單位: | 農藝學系 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-104-1.pdf 目前未授權公開取用 | 2.75 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。