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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 簡國龍(Chien Kuo-Liong) | |
| dc.contributor.author | Yin-Cheng Hsieh | en |
| dc.contributor.author | 謝穎成 | zh_TW |
| dc.date.accessioned | 2021-06-15T11:26:36Z | - |
| dc.date.available | 2016-09-01 | |
| dc.date.copyright | 2016-08-26 | |
| dc.date.issued | 2016 | |
| dc.date.submitted | 2016-08-18 | |
| dc.identifier.citation | 1. NIH. Who Is at Risk for a Stroke? In: NIH National Heart L, and Blood Institute, editor.; 2015.
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J Periodontol 2000;71(10):1554-60. 53. Loos BG, Craandijk J, Hoek FJ, Wertheim-van Dillen PM, van der Velden U. Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol 2000;71(10):1528-34. 54. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000;101(16):1899-906. 55. Khlgatian M, Nassar H, Chou HH, Gibson FC, 3rd, Genco CA. Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cells. Infect Immun 2002;70(1):257-67. 56. Chun YH, Chun KR, Olguin D, Wang HL. Biological foundation for periodontitis as a potential risk factor for atherosclerosis. J Periodontal Res 2005;40(1):87-95. 57. Firatli E. The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years. J Periodontol 1997;68(2):136-40. 58. Glaser C, Matzko M, Reiser M. [Chronic infections of the skeletal system. Their imaging diagnosis]. Radiologe 2000;40(6):547-56. 59. Joshipura KJ, Wand HC, Merchant AT, Rimm EB. Periodontal disease and biomarkers related to cardiovascular disease. J Dent Res 2004;83(2):151-5. 60. Skoog T, Dichtl W, Boquist S, Skoglund-Andersson C, Karpe F, Tang R, et al. Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J 2002;23(5):376-83. 61. Angeli F, Verdecchia P, Pellegrino C, Pellegrino RG, Pellegrino G, Prosciutti L, et al. Association between periodontal disease and left ventricle mass in essential hypertension. Hypertension 2003;41(3):488-92. 62. Desvarieux M, Demmer RT, Rundek T, Boden-Albala B, Jacobs DR, Jr., Papapanou PN, et al. Relationship between periodontal disease, tooth loss, and carotid artery plaque: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke 2003;34(9):2120-5. 63. Leivadaros E, van der Velden U, Bizzarro S, ten Heggeler JM, Gerdes VE, Hoek FJ, et al. A pilot study into measurements of markers of atherosclerosis in periodontitis. J Periodontol 2005;76(1):121-8. 64. Wang CH, Li SH, Weisel RD, Fedak PW, Dumont AS, Szmitko P, et al. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation 2003;107(13):1783-90. 65. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (1). N Engl J Med 1992;326(4):242-50. 66. Fichtlscherer S, Breuer S, Schachinger V, Dimmeler S, Zeiher AM. C-reactive protein levels determine systemic nitric oxide bioavailability in patients with coronary artery disease. Eur Heart J 2004;25(16):1412-8. 67. Persson GR, Mancl LA, Martin J, Page RC. Assessing periodontal disease risk: a comparison of clinicians' assessment versus a computerized tool. J Am Dent Assoc 2003;134(5):575-82. 68. Pussinen PJ, Jousilahti P, Alfthan G, Palosuo T, Asikainen S, Salomaa V. Antibodies to periodontal pathogens are associated with coronary heart disease. Arterioscler Thromb Vasc Biol 2003;23(7):1250-4. 69. Pussinen PJ, Nyyssonen K, Alfthan G, Salonen R, Laukkanen JA, Salonen JT. Serum antibody levels to Actinobacillus actinomycetemcomitans predict the risk for coronary heart disease. Arterioscler Thromb Vasc Biol 2005;25(4):833-8. 70. Mattila KJ, Valle MS, Nieminen MS, Valtonen VV, Hietaniemi KL. Dental infections and coronary atherosclerosis. Atherosclerosis 1993;103(2):205-211. 71. Ramesh A, Soroushian S, Ganguly R. Coincidence of calcified carotid atheromatous plaque, osteoporosis, and periodontal bone loss in dental panoramic radiographs. Imaging Sci Dent 2013;43(4):235-43. 72. Joshipura KJ, Hung HC, Rimm EB, Willett WC, Ascherio A. Periodontal disease, tooth loss, and incidence of ischemic stroke. Stroke 2003;34(1):47-52. 73. Almog DM, Horev T, Illig KA, Green RM, Carter LC. Correlating carotid artery stenosis detected by panoramic radiography with clinically relevant carotid artery stenosis determined by duplex ultrasound. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94(6):768-73. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/49392 | - |
| dc.description.abstract | 背景介紹
此研究將探討牙周局部感染指標與頸部動脈鈣化的關聯。 方法： 此觀察性研究於收集於2011年9月15日-至2012年9月15日台大醫院牙科看診之病人接受全口放射影像攝影(PR)共(2106人次)挑選有台大醫院就診之病歷（642人占30.4%）。以環口放射線攝影檢視：齒槽骨破壞程度、缺齒數、根尖牙周炎、齲齒指數(DMF index)與頸部動脈鈣化之關聯。 結果 :於全口放射片影像上,齒槽骨破壞程度中度比輕微於頸部動脈鈣化之OR值為0.48(95%信賴區間 0.27~0.85)，重度比輕微於得到頸部動脈鈣化上OR值為0.50(95%信賴區間 0.15~1.63) P值=0.039。 結論:臺大醫院病人有口腔感染狀態會增加頸部動脈鈣化的風險，齒槽骨破壞程度輕微，落齒數越高及有根尖牙周炎者，於全口放射影像中發現頸部動脈鈣化風險越高。 | zh_TW |
| dc.description.abstract | INTRODUCTION:
This study aim to investigate the relationships between the severity of periodontal disease , tooth status on carotid artery calcification. METHODS: Based on a cross-sectional study, a total of 2106 dental panoramic graphs (PR)s was selected from National Taiwan University Hospital from sept.15th 2011 to sept.15th 2012. Dental panoramic radiographs (PR) were used to exam the alveolar bone loss , Tooth loss , and apical peritonitis ,Decayed, Missing, And Filled Teeth (DMF index), were used to define the severity of periodontal disease. RESULTS:IN examine paranoiac radiography, the Moderate degree of Alveolar Bone Loss compare with slight degree’s had carotid artery calcification, The Odds Raito is about 0.48 (95% CI 0.27 to 0.85), the Severe degree compare with slightly degree had crotid artery calcification ,the Odds Raito is 0.50 (95% CI 0.15 ~ 1.63) P value = 0.039. CONCLUSIONS: In NTUH patients, with oral infection (with slightly Alveolar Bone Loss ,Tooth loss and apical peritonitis ) had high risk presenting carotid artery calcification in examine PR. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T11:26:36Z (GMT). No. of bitstreams: 1 ntu-105-R99847021-1.pdf: 11954200 bytes, checksum: 6d4173bf3ef411c2fe32766da2056518 (MD5) Previous issue date: 2016 | en |
| dc.description.tableofcontents | 1 實習單位簡介 1
1.1 實習單位提供資源與限制 2 2 背景 3 2.1 頸動脈鈣化與腦中風 3 2.2 環口放射線攝影 4 2.3 頸部動脈鈣化與牙周病 4 2.4 我國牙周疾病嚴重程度抽樣調查 5 2.5 造成口腔感染的因素 5 2.6 牙周疾病 7 2.7 根尖牙周炎 7 2.8 齒槽骨破壞程度 10 2.9 牙周病與心血管疾病的關聯 10 2.10 與過去研究的差異 12 3 研究方法 14 3.1 假設： 14 3.2 實驗設計： 14 3.2.1 納入條件 14 3.2.2 樣本收集流程 15 3.2.3 樣本收集方式 15 3.2.4 受試者排除條件 16 3.2.5 資料輸入類別及方式 16 3.3 資料分析 18 3.3.1 樣本計算方式 18 3.3.2 信度 19 3.3.3 描述性分析 21 3.3.4 羅吉斯迴歸分析 21 4 結果 22 4.1 研究樣本之人口學特性 22 4.2 描述性統計 22 4.2.1 年齡、性別與頸部動脈鈣化的關聯 22 4.2.2 根尖牙周炎 齒槽骨破壞程度 缺牙狀態與頸部動脈鈣化之關聯 23 4.3 羅吉斯迴歸分析 25 4.4 討論 26 4.4.1 優勢與劣勢 27 4.5 限制 29 4.6 結論 30 參考文獻 44 | |
| dc.language.iso | zh-TW | |
| dc.subject | 環口放射片攝影 | zh_TW |
| dc.subject | 齒槽骨破壞程度 | zh_TW |
| dc.subject | 根尖牙周炎 | zh_TW |
| dc.subject | 頸部動脈鈣化 | zh_TW |
| dc.subject | 牙周病 | zh_TW |
| dc.subject | 缺牙 | zh_TW |
| dc.subject | Carotid Artery Calcification | en |
| dc.subject | Alveolar Bone Loss | en |
| dc.subject | Dental panoramic radiographs | en |
| dc.subject | Tooth Loss | en |
| dc.subject | Apical Peritonitis | en |
| dc.title | 以根尖牙周炎作為口腔局部感染指標與頸部動脈鈣化相關探討 | zh_TW |
| dc.title | Apical periodontitis as the index of localized oral infection and carotid artery calcification among adults | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 104-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 鄭景暉(Jeng Jiiang-Huei) | |
| dc.contributor.oralexamcommittee | 杜裕康(Tu Yu-Kang) | |
| dc.subject.keyword | 頸部動脈鈣化,牙周病,環口放射片攝影,缺牙,根尖牙周炎,齒槽骨破壞程度, | zh_TW |
| dc.subject.keyword | Carotid Artery Calcification,Alveolar Bone Loss,Apical Peritonitis,Tooth Loss,Dental panoramic radiographs, | en |
| dc.relation.page | 51 | |
| dc.identifier.doi | 10.6342/NTU201603253 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2016-08-18 | |
| dc.contributor.author-college | 公共衛生學院 | zh_TW |
| dc.contributor.author-dept | 公共衛生碩士學位學程 | zh_TW |
| 顯示於系所單位： | 公共衛生碩士學位學程 | |
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