請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/48482完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 邱銘章(Ming-Chang Chiu) | |
| dc.contributor.author | Mei-Yuan Lin | en |
| dc.contributor.author | 林鎂媛 | zh_TW |
| dc.date.accessioned | 2021-06-15T06:58:38Z | - |
| dc.date.available | 2011-02-20 | |
| dc.date.copyright | 2011-02-20 | |
| dc.date.issued | 2011 | |
| dc.date.submitted | 2011-01-27 | |
| dc.identifier.citation | Reference
Chinese reference 黃俊豪 (2006)。『老化對於噪音環境中傾聽言語時大腦活化之影響:以功能性磁振攝影研究中樞型老年性聽障』(未發表之碩士論文)。台北：台灣大學醫學院臨床醫學研究所碩士論文。 English reference Ashburner, J. (2007). A fast diffeomorphic image registration algorithm. Neuroimage, 38(1), 95-113. Ashburner, J., & Friston, K. (2000). Voxel-based morphometry--the methods. Neuroimage, 11(6), 805-821. Baddeley, A. (1992). Working memory. Science, 255(5044), 556. Benton, A. L., & Hamsher, K. d. (1978). Multilingual Aphasia Examination. Iowa City: AJA associates. Binder, J. (2002). Wernicke aphasia: a disorder of central language processing. Neurological foundations of cognitive neuroscience, 175-238. Binder, J., Frost, J., Hammeke, T., Bellgowan, P., Springer, J., Kaufman, J., et al. (2000). Human temporal lobe activation by speech and nonspeech sounds. Cerebral Cortex, 10(5), 512. Binder, J., Frost, J., Hammeke, T., Cox, R., Rao, S., & Prieto, T. (1997). Human brain language areas identified by functional magnetic resonance imaging. Journal of Neuroscience, 17(1), 353. Binder, J. R., Desai, R. H., Graves, W. W., & Conant, L. L. (2009). Where Is the Semantic System? A Critical Review and Meta-Analysis of 120 Functional Neuroimaging Studies. Cerebral Cortex, 19(12), 2767-2796. Binder, J. R., & Price, C. (2001). Functional Neuroimaging of Language Handbook of functional neuroimaging of cognition,187-252. Cambridge, Mass: The MIT Press. Bolger, D., Perfetti, C., & Schneider, W. (2005). Cross cultural effect on the brain revisited: Universal structures plus writing system variation. Human Brain Mapping, 25(1), 92-104. Booth, J., Burman, D., Meyer, J., Gitelman, D., Parrish, T., & Mesulam, M. (2002). Modality independence of word comprehension. Human Brain Mapping, 16(4), 251-261. Booth, J., Lu, D., Burman, D., Chou, T., Jin, Z., Peng, D., et al. (2006). Specialization of phonological and semantic processing in Chinese word reading. Brain research, 1071(1), 197-207. Bunce, D., Anstey, K., Christensen, H., Dear, K., Wen, W., & Sachdev, P. (2007). White matter hyperintensities and within-person variability in community-dwelling adults aged 60-64 years. Neuropsychologia, 45(9), 2009-2015. Burke, D., MacKay, D., Worthley, J., & Wade, E. (1991). On the tip of the tongue: What causes word finding failures in young and older adults?* 1. Journal of memory and language, 30(5), 542-579. Cabeza, R., Anderson, N., Locantore, J., & McIntosh, A. (2002). Aging gracefully: compensatory brain activity in high-performing older adults. Neuroimage, 17(3), 1394-1402. Cabeza, R., Daselaar, S., Dolcos, F., Prince, S., Budde, M., & Nyberg, L. (2004). Task-independent and task-specific age effects on brain activity during working memory, visual attention and episodic retrieval. Cerebral Cortex, 14(4), 364. Calautti, C., Naccarato, M., & Jones, P. (2007). The relationship between motor deficit and hemisphere activation balance after stroke: a 3T fMRI study. Neuroimage, 34, 322-331. Catani, M., Howard, R., Pajevic, S., & Jones, D. (2002). Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage, 17(1), 77-94. Chee, M., O'Craven, K., Bergida, R., Rosen, B., & Savoy, R. (1999). Auditory and visual word processing studied with fMRI. Human Brain Mapping, 7(1), 15-28. Chee, M., Weekes, B., Lee, K., Soon, C., Schreiber, A., Hoon, J., et al. (2000). Overlap and dissociation of semantic processing of Chinese characters, English words, and pictures: evidence from fMRI. Neuroimage, 12(4), 392-403. Chen, T., Chen, Y., Cheng, T., Hua, M., Liu, H., & Chiu, M. (2009). Executive dysfunction and periventricular diffusion tensor changes in amnesic mild cognitive impairment and early Alzheimer's disease. Human Brain Mapping, 30(11), 3826-3836. Craik, F. I. M., & Salthouse, T. A. (2008). The handbook of aging and cognition. New York: Psychology Press. Davis, S., Dennis, N., Daselaar, S., Fleck, M., & Cabeza, R. (2007). Que PASA? The posterior anterior shift in aging. Cerebral Cortex, 18(5), 1201-1209. Frackowiak, R., Friston, K., & Frith, C. (2003). An overview of speech comprehension and production Human Brain Function, 2nd edn (pp. 517-529). New York: Academic Press. Friedman, L., Stern, H., Brown, G., Mathalon, D., Turner, J., Glover, G., et al. (2008). Test¡Vretest and between site reliability in a multicenter fMRI study. Human Brain Mapping, 29(8), 958-972. Frost, J., Binder, J., Springer, J., Hammeke, T., Bellgowan, P., Rao, S., et al. (1999). Language processing is strongly left lateralized in both sexes: Evidence from functional MRI. Brain, 122(2), 199. Grady, C., Maisog, J., Horwitz, B., Ungerleider, L., Mentis, M., Salerno, J., et al. (1994). Age-related changes in cortical blood flow activation during visual processing of faces and location. Journal of Neuroscience, 14(3), 1450. Grady, C., Springer, M., Hongwanishkul, D., Mcintosh, A., & Winocur, G. (2006). Age-related changes in brain activity across the adult lifespan. Journal of Cognitive Neuroscience, 18(2), 227-241. Gutchess, A., Welsh, R., Hedden, T., Bangert, A., Minear, M., Liu, L., et al. (2005). Aging and the neural correlates of successful picture encoding: frontal activations compensate for decreased medial-temporal activity. Journal of Cognitive Neuroscience, 17(1), 84-96. Hickok, G., & Poeppel, D. (2007). The cortical organization of speech processing. Nature Reviews Neuroscience, 8(5), 393-402. Horwitz, B., Rumsey, J., & Donohue, B. (1998). Functional connectivity of the angular gyrus in normal reading and dyslexia. Proceedings of the National Academy of Sciences of the United States of America, 95(15), 8939. Howard, D., Patterson, K., WISE, R., Brown, W., FRISTON, K., WEILLER, C., et al. (1992). The cortical localization of the lexicons: Positron emission tomography evidence. Brain, 115(6), 1769. Johnson, S., Saykin, A., Flashman, L., McAllister, T., O Jile, J., Sparling, M., et al. (2001). Similarities and differences in semantic and phonological processing with age patterns of functional MRI activation. Aging, Neuropsychology, and Cognition, 8(4), 307-320. Kuo, W., Yeh, T., Duann, J., Wu, Y., Ho, L., Hung, D., et al. (2001). A left-lateralized network for reading Chinese words: a 3 T fMRI study. Neuroreport, 12(18), 3997. Liebenthal, E., Desai, R., Ellingson, M., Ramachandran, B., Desai, A., & Binder, J. (2010). Specialization along the left superior temporal sulcus for auditory categorization. Cerebral Cortex, 20(12), 2958-2970. Liu, L., Deng, X. X., Peng, D. L., Cao, F., Ding, G. S., Jin, Z., et al. (2009). Modality- and Task-specific Brain Regions Involved in Chinese Lexical Processing. Journal of Cognitive Neuroscience, 21(8), 1473-1487. Lustig, C., Snyder, A. Z., Bhakta, M., O'Brien, K. C., McAvoy, M., Raichle, M. E., et al. (2003). Functional deactivations: Change with age and dementia of the Alzheimer type. Proceedings of the National Academy of Sciences of the United States of America, 100(24), 14504-14509. Madden, D., Langley, L., Denny, L., Turkington, T., Provenzale, J., Hawk, T., et al. (2002). Adult Age Differences in Visual Word Identification: Functional Neuroanatomy by Positron Emission Tomography* 1. Brain and cognition, 49(3), 297-321. Madden, D., Turkington, T., Coleman, R., Provenzale, J., DeGrado, T., & Hoffman, J. (1996). Adult age differences in regional cerebral blood flow during visual word identification: Evidence from H215O PET. Neuroimage, 3(2), 127. Madden, D. J., Turkington, T. G., Provenzale, J. M., Denny, L. L., Langley, L. K., Hawk, T. C., et al. (2002). Aging and attentional guidance during visual search: Functional neuroanatomy by positron emission tomography. [Article]. Psychology and Aging, 17(1), 24-43. McGeown, W., Shanks, M., Forbes-McKay, K., & Venneri, A. (2009). Patterns of brain activity during a semantic task differentiate normal aging from early Alzheimer's disease. Psychiatry Research: Neuroimaging, 173(3), 218-227. Meltzer, C., Zubieta, J., Brandt, J., Tune, L., Mayberg, H., & Frost, J. (1996). Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology, 47(2), 454. Morrell, C., Gordon-Salant, S., Pearson, J., Brant, L., & Fozard, J. (1996). Age-and gender-specific reference ranges for hearing level and longitudinal changes in hearing level. Journal of the Acoustical Society of America, 100(4), 1949-1970. Neilson, K., Douville, K., Seidenberg, M., Woodard, J., Miller, S., & Franczak, M. (2006). Age- related functional recruitment for famous name recognition: an event-related fMRI study. Neurobiology of aging, 27, 1494-1504. Price, C., Thierry, G., & Griffiths, T. (2005). Speech-specific auditory processing: where is it? Trends in cognitive sciences, 9(6), 271-276. Price, C. J. (2010). The anatomy of language: a review of 100 fMRI studies published in 2009 Year in Cognitive Neuroscience 2010, 1191 (1), 62-88 Raz, N. (2005). The aging brain observed in vivo: Differential changes and their modifiers. Cognitive neuroscience of aging: Linking cognitive and cerebral aging, 19-57. New York: Oxford University Press. Raz, N., Lindenberger, U., Rodrigue, K., Kennedy, K., Head, D., Williamson, A., et al. (2005). Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. Cerebral Cortex, 15(11), 1676. Rorden, C., & Brett, M. (2000). Stereotaxic display of brain lesions. Behav Neurol, 12(4), 191-200. Sandstrom, C., Krishnan, S., Slavin, M., Tran, T., Doraiswamy, P., & Petrella, J. (2006). Hippocampal atrophy confounds template-based functional MR imaging measures of hippocampal activation in patients with mild cognitive impairment. American Journal of Neuroradiology, 27(8), 1622. Springer, J., Binder, J., Hammeke, T., Swanson, S., Frost, J., Bellgowan, P., et al. (1999). Language dominance in neurologically normal and epilepsy subjects: a functional MRI study. Brain, 122(11), 2033. Tan, L., Laird, A., Li, K., & Fox, P. (2005). Neuroanatomical correlates of phonological processing of Chinese characters and alphabetic words: A meta analysis. Human Brain Mapping, 25(1), 83-91. Tan, L., Spinks, J., Gao, J., Liu, H., Perfetti, C., Xiong, J., et al. (2000). Brain activation in the processing of Chinese characters and words: a functional MRI study. Human Brain Mapping, 10(1), 16-27. Tan, L. H., Laird, A. R., Li, K., & Fox, P. T. (2005). Neuroanatomical correlates of phonological processing of Chinese characters and alphabetic words: a meta-analysis. Human Brain Mapping, 25(1), 83-91. Verhaeghen, P. (2003). Aging and vocabulary score: a meta-analysis. Psychology and Aging, 18(332-339). Vigneau, M., Beaucousin, V., Herve, P., Duffau, H., Crivello, F., Houde, O., et al. (2006). Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing. Neuroimage, 30(4), 1414-1432. Walter, B., Blecker, C., Kirsch, P., Sammer, G., Schienle, A., Stark, R., et al. (2003). MARINA: an easy to use tool for the creation of MAsks for Region of INterest Analyses. Wernicke, C. (1874). Der aphasische symptomencomplex. Cohn & Weigert Breslau. Wingfield, A. (1996). Cognitive factors in auditory performance: context, speed of processing, and constraints of memory. Journal of the American Academy of Audiology, 7(3), 175. Xiao, Z., Zhang, J., Wang, X., Wu, R., Hu, X., Weng, X., et al. (2005). Differential activity in left inferior frontal gyrus for pseudowords and real words: an event-related fMRI study on auditory lexical decision. Human Brain Mapping, 25(2), 212-221. Yendiki, A., Greve, D., Wallace, S., Vangel, M., Bockholt, J., Mueller, B., et al. (2010). Multi-site characterization of an fMRI working memory paradigm: Reliability of activation indices. Neuroimage, 53(1),119-131. Zou, K., Greve, D., Wang, M., Pieper, S., Warfield, S., White, N., et al. (2005). Reproducibility of Functional MR Imaging: Preliminary Results of Prospective Multi-institutional Study Performed by Biomedical Informatics Research Network1. Radiology, 237(3), 781. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/48482 | - |
| dc.description.abstract | 人與人溝通的過程中，語言是最為常用的一種傳遞工具，透過'聽'而獲得成功的理解，此歷程包含了對語音的接收辨認及對語意的理解判斷，本研究旨在探討聽覺理解歷程於大腦皮質活化的情形，本研究又分為兩部份，第一部分是透過中文和日文之比較初探語音和語意歷程的相同與相異之處，建基於對語言系統的了解，進一步探究在時間脈絡下，老化可能帶來的影響，過去行為研究指出正常老化所導致的詞彙知識缺損並不明顯，但於功能性磁振造影研究中普遍發現，老化可能帶來腦區活化的程度下降，同時藉由額葉或其他較高階處理的區域之活化上升來補償以維持功能，然而老化於聽覺語意歷程之影響的實證研究仍相當缺乏，此為第二部分之研究動機。本研究使用功能性磁振造影及聽覺語意判斷作業，以感興趣區域(Regions of interest)的方式分析，並於研究二中同時控制大腦皮質萎縮的影響。本研究之研究一發現，在左側顳頂葉(temporoparietal regions)，包括緣上回(supramarginal gyrus)以及背側的額葉額下回(dorsal portion of inferior frontal gyrus)所形成的語音迴路在中日文語言系統中有差異，也證實語意處理在跨語言特性時活化情形較為接近。研究二結果顯示，在表現維持相同水準的情況下，老年組在負責語言知覺處理的左側上顳葉回(superior temporal gyrus)呈現顯著的功能下降，但在額葉或負責語音及語意歷程的區域並無明顯補償效應；同時，老年組於語意作業的行為表現在反應速度上有明顯下降，且與多處大腦皮質的萎縮呈負相關。本研究結果顯示，支持過去行為研究的結果，正常老化對語音處理或語意知識的功能影響不大，但語意判斷之反應慢化，且上顳葉回在行為表現未受影響之前即出現功能的降低，可能代表語音知覺的改變。 | zh_TW |
| dc.description.abstract | The aim of this study was to investigate the patterns of cortical activation during auditory semantic processing using fMRI and the effects of aging on this network. We reviewed current research for cortical activation patterns of auditory semantic processing and summarized relevant neuroimaging models of aging that showed consistent compensatory pattern of age-related changes in brain activity. We first examined similarities and differences in auditory phonological and semantic processing between Chinese and Japanese language. Based on language networks from younger population, we then examined compensatory pattern for auditory semantic processing in healthy elderly participants. We applied functional MRI and ROI analysis to investigate the activation patterns of language-related regions in healthy young and old participants. Young Japanese participants showed greater activation in temporoparietal regions including left supramarginal gyrus and left dorsal portion of inferior gyrus compared to young Taiwanese participants during speech perception processing of their respective languages. Japanese and Chinese language elicited similar activity in the semantic network, especially in the angular gyrus, middle temporal gyrus and the ventral portion of inferior frontal gyrus. In terms of aging effects, elderly Japanese adults had decreased left superior temporal gyrus activation compared to the younger Japanese, suggesting an initial change in the semantic language network. In addition, a general slowing during semantic judgment associated with the volumetric decline was observed. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T06:58:38Z (GMT). No. of bitstreams: 1 ntu-100-R96227206-1.pdf: 4382292 bytes, checksum: b35fd1852598ed463467d2e488fdee8f (MD5) Previous issue date: 2011 | en |
| dc.description.tableofcontents | CONTENTS
Chapter 1 introduction 1 Auditory Language Processing 2 Chinese Auditory Semantic Processing 6 Semantic Processing and Aging 11 Chapter 2 Methods 19 Participants 19 Neuropsychological Screening 21 fMRI Session 21 Image Acquisition 23 Image Analysis 24 fMRI Preprocessing 24 ROI Analysis 25 Atrophy measurement 28 Statistical Analysis 30 Chapter 3 Results 32 Study1 32 Study2 39 Chapter 4 Discussion 45 References 59 Appendix 67 | |
| dc.language.iso | en | |
| dc.subject | 功能性磁振造影 | zh_TW |
| dc.subject | 老化 | zh_TW |
| dc.subject | 聽覺 | zh_TW |
| dc.subject | 語音及語意歷程 | zh_TW |
| dc.subject | 中日文比較 | zh_TW |
| dc.subject | aging | en |
| dc.subject | phonological processing | en |
| dc.subject | semantic processing | en |
| dc.subject | Chinese | en |
| dc.subject | Japanese | en |
| dc.subject | fMRI | en |
| dc.title | 以功能性磁振造影初探聽覺語言歷程:
中日語言比較及老化影響 | zh_TW |
| dc.title | The Neural Correlates of Auditory Language Processing between Chinese and Japanese and the Effects of Aging:
A Preliminary Investigation Using fMRI | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 99-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 張玉玲(Yu-LingChang) | |
| dc.subject.keyword | 聽覺,語音及語意歷程,中日文比較,老化,功能性磁振造影, | zh_TW |
| dc.subject.keyword | phonological processing,semantic processing,Chinese,Japanese,fMRI,aging, | en |
| dc.relation.page | 67 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2011-01-27 | |
| dc.contributor.author-college | 理學院 | zh_TW |
| dc.contributor.author-dept | 心理學研究所 | zh_TW |
| 顯示於系所單位： | 心理學系 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-100-1.pdf 未授權公開取用 | 4.28 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。