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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 黃升龍(Sheng-Lung Huang) | |
dc.contributor.author | Tuan-Shu Ho | en |
dc.contributor.author | 何端書 | zh_TW |
dc.date.accessioned | 2021-05-14T17:48:19Z | - |
dc.date.available | 2020-03-13 | |
dc.date.available | 2021-05-14T17:48:19Z | - |
dc.date.copyright | 2015-03-13 | |
dc.date.issued | 2015 | |
dc.date.submitted | 2015-02-09 | |
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dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/4833 | - |
dc.description.abstract | With the co-drawing laser-heated pedestal growth (CD-LHPG) method, various crystal fibers were developed. Ce:YAG, Ce:YSO, and Ti:sapphire crystal fibers grown in our laboratory generate broadband, continuous-wave, and near-Gaussin florescence spectra under laser diode pumping, and are suitable to be the light source of optical coherence tomography (OCT) system. The Ce:YSO crystal fiber light source has a broadband fluorescence emission in the blue wavelength range, and the OCT system based on the Ce:YSO light source can achieve a 0.6-μm axial resolution on single cell measurement, and 0.5-μm axial resolution on examination of panel devices.
The crystal fiber light source has high brightness, large numerical aperture and multi-transverse-mode, and the design rules for crystal-fiber-based OCT are much different from the commercial OCT systems with tunable lasers or pig-tailed superluminescent diodes (SLD) as light sources. In this dissertation, the issues related to the fabrication of spectral-domain and full-field OCT systems are also presented and discussed. The crystal-fiber-based OCT systems are not only capable for high-resolution structural imaging, but also suitable for functional analysis. The broadband property of crystal fiber light sources also provides a large available bandwidth for spectroscopic analysis. Their near-Gaussian lineshapes also help to reduce the crosstalk problem for time-frequency analysis. A series of OCT systems are were implemented for the study of various corneal properties, and the performances were tested with human eye models. The OCT tonometry system in our laboratory, can achieve high speed intraocular pressure measurement, and to provide information related to the corneal elasticity. With carrier-analysis-based algorithm, a full-field OCT keratometry and achieve two-dimensional curvature mapping within 6-mm diameter within 70 milliseconds. An OCT approach for characterization of absorptive thin-film materials was developed, which can obtain the thickness and optical properties of absorptive films with micrometer thickness. With the Ce:YAG and Ce:YSO crystal fiber light source, the systems are able to measure the refractive index and extinction coefficient spectra from 400 to 600 nm, and a 0.15% precision was achieved on the film thickness measurement on various absorptive films. | en |
dc.description.provenance | Made available in DSpace on 2021-05-14T17:48:19Z (GMT). No. of bitstreams: 1 ntu-104-F95941098-1.pdf: 6560994 bytes, checksum: 060c1cea9b383e818b2183e44e2fa1f8 (MD5) Previous issue date: 2015 | en |
dc.description.tableofcontents | 口試委員會審定書 i
致謝辭 ii ABSTRACT iii 中文摘要 iv CONTENTS v LIST OF FIGURES vii LIST OF TABLES xiv Chapter 1 Introduction to Optical Coherence Tomography 1 1.1 Principle of Optical Coherence Tomography 2 1.2 Signal-to-noise Ratio of Optical Coherence Tomography 7 Chapter 2 Fabrication of Broadband Crystal Fiber Light Source 10 2.1 Laser-Heated Pedestal Growth System 11 2.2 Co-drawing Laser-heated Pedestal Growth 14 2.3 Broadband Crystal Fiber Light Source 16 2.3.1 Ce:YAG Single-clad Crystal Fiber 16 2.3.2 Ti:sapphire Single-clad Crystal Fiber 19 2.3.3 Ce:YSO Single-clad Crystal Fiber 21 Chapter 3 OCT Systems based on Crystal Fiber Light Sources 27 3.1 Crystal-fiber based Spectral-domain OCT 28 3.1.1 Ti:sapphire-Crystal-fiber based Spectral-domain OCT 28 3.1.2 Ce:YAG Spectral-domain OCT 44 3.1.3 Ti:sapphire parallel SD-OCT 46 3.2 Full-field OCT 49 Chapter 4 OCT Systems for Corneal Measurements 70 4.1 OCT Tonometer and Pachymeter 71 4.1.1 OCT Tonometer with Air-puff Module 72 4.1.2 OCT Pachymeter with Yb:fiber Light Source 79 4.2 OCT Keratometer 87 4.2.1 Placido karatometer 87 4.2.2 Curvature Calculation Based on Topographic Data 90 4.2.3 Experimental Considerations of OCT Keratometer 95 Chapter 5 Spectral-domain Optical Coherence Tomography on Thin-film Characterization 114 5.1 Thin-film Optical Constant Estimation with Nonlinear Regression 115 5.1.1 Numerical Model of the Thin-film Sample 115 5.1.2 Hilbert Transform in Spectral Domain for the Phase Acquisition 117 5.1.3 Interface Signal Separation 119 5.1.4 Data Acquisition Procedure 122 5.1.5 Phase Ambiguity Issue 124 5.1.6 Gauss-Newton’s Algorithm 126 5.2 Simultaneous Characterization of Optical Constants on Thin-film Color Filter with Crystal-fiber-based SD-OCT 128 5.2.1 Substrate-incident Scheme 129 5.2.2 Experimental Result of Spectroscopic SD-OCT 130 5.2.3 Error Analysis 135 5.3 Spectroscopic FF-OCT Approach 137 5.3.1 FF-OCT with a Special-designed Mirau Objective 138 5.3.2 Experiential Result of Spectroscopic FF-OCT 139 Chapter 6 Conclusions 141 Reference 143 | |
dc.language.iso | en | |
dc.title | 基於寬頻晶體光纖元件之功能性光學同調斷層掃描術之研究 | zh_TW |
dc.title | Functional Optical Coherence Tomography Based on Broadband Crystal Fiber Light Source | en |
dc.type | Thesis | |
dc.date.schoolyear | 103-1 | |
dc.description.degree | 博士 | |
dc.contributor.oralexamcommittee | 孫家偉(Chia-Wei Sun),曾雪峰(Snow Tseng),葉秉慧(Pinghui Sophia Yeh),詹明哲(Ming-Che Chan),羅裕龍(Yu-Lung Lo) | |
dc.subject.keyword | 光學,光源,晶體,光纖,光學同調斷層掃描,材料檢測, | zh_TW |
dc.subject.keyword | optics,light source,crystal,fiber,optical coherence tomography,material characterization, | en |
dc.relation.page | 149 | |
dc.rights.note | 同意授權(全球公開) | |
dc.date.accepted | 2015-02-09 | |
dc.contributor.author-college | 電機資訊學院 | zh_TW |
dc.contributor.author-dept | 光電工程學研究所 | zh_TW |
顯示於系所單位: | 光電工程學研究所 |
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