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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 賴裕和(Yeur-Hur Lai) | |
dc.contributor.author | Yen-Ju Chen | en |
dc.contributor.author | 陳彥汝 | zh_TW |
dc.date.accessioned | 2021-06-15T05:12:55Z | - |
dc.date.available | 2012-09-13 | |
dc.date.copyright | 2010-09-13 | |
dc.date.issued | 2010 | |
dc.date.submitted | 2010-07-23 | |
dc.identifier.citation | 中文文獻
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Concurrent control study of different radiotherapy for primary nasopharyngeal carcinoma: intensity-modulated radiotherapy versus conventional radiotherapy. Ai Zheng, 28(11), 1143-1148. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46511 | - |
dc.description.abstract | 鼻咽癌為台灣盛行的頭頸部腫瘤之ㄧ,其治療引起的副作用包含牙關緊閉、唾液減少及營養不良等將對病患生活帶來長期影響,隨著存活率的提升,病患同時面臨的生理、心理問題值得更深入的探討。故本研究目的為探討鼻咽癌病患於接受放射線治療後主要生理(牙關緊閉、唾液減少、營養不良)與心理(焦慮、憂鬱)之衝擊,研究採橫斷式相關性設計,以北部某醫學中心耳鼻喉科門診之個案為研究母群體,採立意取樣,經診斷為鼻咽癌且結束積極腫瘤治療介於三個月至五年內之病患納入收案,於民國98年12月30日至99年5月4日,共取得108名個案資料。研究工具以結構式問卷收集病患資料,包括基本資料表、下頜功能不全量表、口乾量表、進食困難量表、迷你營養評估量表、及醫院焦慮量表,並測量病患張口度、無刺激及有刺激之唾液流速。研究結果顯示放射線治療結束時間與牙關緊閉呈顯著相關;放射線治療劑量與口乾嚴重度呈顯著相關;牙關緊閉、口乾、進食困難、營養不良之情形與憂鬱亦呈顯著相關;營養狀態之顯著預測因子包含體重、下頜功能不全嚴重度、憂鬱及身體功能狀態,因此,臨床照護應在治療過程維持病患體重及身體功能狀態,並預防憂鬱及治療後牙關緊閉的發生,以減少治療後病患營養不良的情形;本研究亦提供臨床工作者對此議題有初步了解及實證依據,建議未來針對治療後的副作用發展有效的介入性措施,以改善病患治療後生理及心理之問題。 | zh_TW |
dc.description.abstract | Nasopharyngeal carcinoma is one of prevalent head and neck cancer in Taiwan. The complications after definitive treatments including trismus, dry mouth, and malnutrition have a long-term impact on patients’ quality of life. With the increase in survival rate, the physiological and psychological issues faced by patients need to be more concerned and explored. The purpose of the study was to explore the impact of radiotherapy on nasopharyngeal carcinoma patients' physical and psychological aspects. The physical aspect includes trismus, dry mouth, and malnutrition and the psychological aspect includes anxiety and depression. A cross-sectional study with purposive sampling was conducted at department of otolaryngology of a medical center in Northern Taiwan. The inclusion criteria for participants were diagnosed with nasopharyngeal carcinoma patients receiving radiotherapy and three mouths to five years after completion of treatments. Between December 2009 and May 2010, the eligible 108 patients were enrolled and assessed by the structured questionnaires including the form of basic information, Mandibular Function Impairment Questionnaire (MFIQ), Xerostomia Questionnaire (XQ), Mini Nutrition Assessment (MNA), Level of Eating Difficulty Scale (LEDS), Hospital Anxiety and Depression Scale (HADS). Maximal interincisor opening and salivary output measured by collecting unstimulated and stimulated whole saliva were also measured in the study. The results showed (1) there was significant correlation between the trismus and the period of time after completion of treatments. (2) there was significant correlation between the dose of the radiation and the severity of dry mouth. (3) there was significant correlation among the severity of trismus, dry mouth, malnutrition, and depression. (4) the predictors of nutrition status were body weight, the severity of mandibular function impairment, depression, and kps. Thus, it should be maintained in the treatments of patients with body weight and kps in clinical practice, and prevent depression and the occurrence of trismus after treatments to reduce malnutrition in patients. Furthermore, our results supply health providers with the knowledge and evidence base. Further researchers should develop the effective intervention for the complications of treatments to enhance patients’ physiology and psychology. | en |
dc.description.provenance | Made available in DSpace on 2021-06-15T05:12:55Z (GMT). No. of bitstreams: 1 ntu-99-R97426004-1.pdf: 570109 bytes, checksum: cda86b2c4545185f99245c580b8fd89a (MD5) Previous issue date: 2010 | en |
dc.description.tableofcontents | 中文摘要 IV
英文摘要 V 第一章 緒論 1 第一節 研究動機與重要性 1 第二節 研究目的 2 第二章 文獻查證 3 第一節 鼻咽癌及其治療 3 第二節 牙關緊閉 7 第三節 唾液減少 10 第四節 癌症病人營養狀態之相關概念 14 第五節 癌症病患之心理衝擊 18 第三章 研究方法 20 第一節 研究架構 20 第二節 研究問題 21 第三節 研究假設 22 第四節 名詞解釋及操作型定義 23 第五節 研究設計 24 第六節 研究場所及對象 25 第七節 研究工具 26 第八節 資料收集 30 第九節 資料處理及分析 31 第十節 研究倫理考量 33 第四章 研究結果 34 第一節 鼻咽癌病患之人口學特性與疾病相關資料 34 第二節 鼻咽癌病患之牙關緊閉情形 35 第三節 鼻咽癌病患之口乾情形 37 第四節 鼻咽癌病患之營養狀況 38 第五節 鼻咽癌病患之焦慮、憂鬱現況 40 第六節 鼻咽癌病患生理與心理狀態之相關性 41 第五章 討論 42 第一節 鼻咽癌患者牙關緊閉與病人特質及疾病治療之關係 42 第二節 鼻咽癌患者唾液減少與病人特質及疾病治療之關係 44 第三節 鼻咽癌患者牙關緊閉、口乾與營養不良之關係 46 第四節 鼻咽癌患者生理狀態的牙關緊閉、口乾、營養不良情形,與 心理狀態焦慮、憂鬱之關係 47 第六章 結論與建議 49 第一節 結論 49 第二節 研究限制 50 第三節 建議 51 參考文獻 52 表目錄 表一 本研究主觀、客觀測量方法 29 表二 統計分析方法 32 表三 病患基本資料 63 表四 病患疾病及治療特性 64 表五 下頜功能不全之活動及咀嚼食物困難度排序一覽表 65 表六 張口測量值、下頜功能不全嚴重度與基本屬性、疾病治療屬性之單 因子變異數分析或t檢定表 66 表七 張口測量、下頜功能不全嚴重度與顳頜關節之放射線劑量、與放射 線治療結束時間相關性 67 表八 口乾嚴重程度一覽表 68 表九 口乾嚴重度之變異數分析及t檢定 69 表十 放射線治療結束時間、腮腺放射劑量、有無刺激之唾液流速及口乾 嚴重度之相關性分析 70 表十一 迷你營養評估子題分佈一覽表 71 表十二 進食困難量嚴重度排序一覽表 74 表十三 生理狀態(營養、進食困難、口乾、下頜功能不全)與心理狀態 (焦慮、憂鬱)之相關性 75 表十四 營養之預測因子 76 圖目錄 圖一 研究架構 20 | |
dc.language.iso | zh-TW | |
dc.title | 接受放射線治療之鼻咽癌患者牙關緊閉、唾液減少與營養狀態之探討 | zh_TW |
dc.title | Trismus, Xerostomia, and Nutrition Status on Nasopharyngeal Carcinoma Patients Receiving Radiotherapy | en |
dc.type | Thesis | |
dc.date.schoolyear | 98-2 | |
dc.description.degree | 碩士 | |
dc.contributor.coadvisor | 王成平(Cheng-Ping Wang),陳淑卿(Shu-Ching Chen) | |
dc.contributor.oralexamcommittee | #VALUE! | |
dc.subject.keyword | 鼻咽癌,放射治療,牙關緊閉,口乾,營養,焦慮憂鬱, | zh_TW |
dc.subject.keyword | Nasopharyngeal Carcinoma,Radiotherapy,Trismus,Dry Mouth,Nutrition,Anxiety and Depression, | en |
dc.relation.page | 76 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2010-07-23 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 護理學研究所 | zh_TW |
顯示於系所單位: | 護理學系所 |
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