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標題: | 動態式脊椎固定系統的穩定程度對植入節與鄰近節活動度與椎間核壓力影響 Effects of Spinal Dynamic Stabilizer Constraints on the Stability and Intradiscal Pressure of Bridged and Adjacent Disc |
作者: | Chi-Wen Wang 王奇文 |
指導教授: | 王兆麟 |
關鍵字: | 動態式脊椎固定系統,活動度,椎間核壓力,生物力學, dynamic stabilization system,range of motion,intradiscal pressure,biomechanics, |
出版年 : | 2010 |
學位: | 碩士 |
摘要: | Summary of Background Data: Laminectomy with screw-rod fixation is a common surgical procedure for unstable spinal column and assorted spinal disorders. The fixation provides strong stabilization at the cost of spinal normal motion. The immobilization of fused motion segment may induce the motion compensation at the adjacent level and then cause early degeneration. The dynamic stabilization system, a flexible spinal fixation device, is designed to preserve the normal spinal motion and avoid adjacent level degeneration. However, cases of adjacent level degeneration after dynamic stabilization are reported, which indicates the current stabilization system may still be too rigid. The ultimate flexibility for the dynamic stabilization system is not yet concluded. The purpose of this study is to find the variation of motion compensation and intradiscal pressure (IDP) in adjacent motion segment at different extent of fixation constraint.
Materials and methods: Eight 4-level lumbar motion segments were dissected from 6-month old pigs. A home-made dynamic spinal stabilizer was designed to control the range of motion (ROM) of the implanted motion segment. This stabilizer is able to control the ROM of motion segment by adjusting the block and shaft for linear and rotary constraints. The ROM of total and individual level of intact and injured lumbar spine under 6 Nm flexion and extension pure moment were first calculated from the motion of flags attached to the vertebrae. The injury was created by damaging the mid level bilateral facet joints and surrounding ligaments. After the injury, the injury level was implanted by a tradition rigid fixation device. Then, an angular displacement controlled rotation was applied to find the individual level ROM. The magnitude of angular rotation is the one of total ROM recorded at injury condition. The difference of ROM of mid level at injury and rigid fixed conditions was divided into 9 internals. Then, the home-made dynamic stabilizer was implanted to tune the ROM of mid level to these 9 intervals at the same displacement controlled rotation. The ROM and IDP in mid and adjacent cranial level of all setting were recorded. Results: During the flexion, after the facet injury, the ROM of mid level increased from 4.0 (SD 0.8) to 8.0 (SD 2.3) degree, but the ROM of adjacent level remained similar. The loading conditions for the rigid and the 9 stabilization constraints were 17.2 (SD 3.4) and 9.7 (SD 1.2) degree for flexion and extension angular displacement control. After the rigid fixation, the ROM of mid level decreased to 2.4 (SD 0.7) degree, but the ROM of adjacent level was compensated (i.e., increased) to 6.7 (SD 1.7) degree. As the ROM of mid level increased with the loose of stabilizer, the ROM of adjacent level decreased. It was found that, the ROMs of mid level and adjacent level were similar when the stabilizer was set from 40% to 80% looseness. During the extension, the trend was similar to the one during extension, except that the ROMs of mid level and adjacent level were similar when the stabilizer was set from 30% to 60% looseness. For an intact motion segment, the IDP of mid level and adjacent level were 0.86 (SD 0.79) bar and 0.98 (SD 1.73) bar during 6 Nm extension, and were 6.29 (SD 2.61) bar and 6.27 (SD 1.12) bar during 6 Nm flexion. The injury of posterior elements significantly increased the IDP of injury level to 6.18 (SD 2.81) bar (p=0.003) during 6 Nm extension, but less affected the IDP of adjacent level. The posterior injury did not affect the IDP of injury level and adjacent level during flexion. The rigid fixation reduced the IDP of implanted level and adjacent level of injured spinal column to 1.59 (SD 0.94) bar (p=0.002) and 1.78 (SD 1.89) bar (p=0.752) at the same extension deformation. However, the rigid fixation increased the IDP of implant level and adjacent level of injured spinal column to 8.22 (SD 3.83) bar (p=0.506) and 13.41 (SD 9.77) bar (p=0.046) at the same flexion deformation. Compared to the rigid fixation system, the dynamic spinal stabilization at all constraint level did not affect the IDP during the extension motion. However, the stabilization system did reduce the IDP of adjacent level when the constraint was set from 20% to 90% looseness during the flexion motion. Conclusions: This study proved the concept of tuning a dynamic spine stabilizer to be feasible. The degree of motion compensation of adjacent level is contradicted to the looseness of dynamic stabilizer. We found the optimal looseness to be from 40% to 80% for flexion and from 30% to 60% for extension. Otherwise, the dynamic stabilizer can both reduce the elevated IDP of implanted level due to injury during extension, and the elevated IDP of adjacent level due to rigid fixation during flexion. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46192 |
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顯示於系所單位: | 醫學工程學研究所 |
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